Oligosaccharides

<p>Benzyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is an oligosaccharide that is synthesized from D-(+)-galactose, D-(+)-glucose and benzyl alcohol. This product can be used for the modification of saccharides and has been shown to have a high purity. It has been fluorinated at the alpha position and glycosylated with acetamidobenzoyl group. The molecular weight of this product is 378.12 g/mol. CAS No.: 53167-38-7</p>

<p>A antigen pentasaccharide Type I I, possible use in antiviral development</p>

<p>Key synthetic precursor for the synthesis of lacto-oligosaccharides</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarodecaose is reported to have potential for novel cosmeceuticals.</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Unusual lactose sulphate isolated from canine milk (beagle-Canis familiaris), which does not appear to have previously been isolated from milk or other natural sources. The structure was established by 2D NMR spectroscopy and mass spectrometry.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarotetraose is reported to have potential for novel cosmeceuticals.</p>

<p>Allyl 2,4,6-tri-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3-O-benzyl a -D -mannopyranoside is a glycosylated oligosaccharide. It is synthesized from 3,4,6 tri O acetyl 2 deoxy 2 phthalimido b D glucopyranosyl chloride and allyl alcohol by the click reaction with sodium azide in the presence of palladium catalysis. This product has been fluorinated at the 6 position of allose. The purity of this product is high and it has been modified on the saccharide chain with methyl groups at the C1 and C2 positions of glucose. Allyl 2,4,6 tri O (3 4 6 tri O acetyl 2 deoxy 2 phthalimido b D gluc</p>

<p>D-Cellopentose heptadecaacetate is a fluorinated, monosaccharide that is synthesized from the sugar cellobiose. It is an oligosaccharide and a complex carbohydrate with one of its glycosidic bonds modified by methylation. D-Cellopentose heptadecaacetate has been shown to be effective in inhibiting glycosylation reactions and can be used as a sugar substitute or for custom synthesis. This product has been shown to have high purity and is available at CAS No. 83058-38-2.</p>

<p>Milk oligosaccharide; antigen; expressed on gastric mucosa and cancer cells</p>

<p>4-O-Methyl-alpha-D-glucurono-beta-D-xylan is produced by the hydrolysis of xylan.  It can be used in studies to find new soluble chromogenic substrates for the assay of xylanases and glucanases.</p>

<p>4-Methoxyphenyl 4-O-(4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-2-O-levulinoyl-b-D-glucopyranosyl)-3,6-di-O-benzyl -2,6'-dideoxygalactopyranoside is a modification of the natural carbohydrate galactose. The sugar moiety has been methylated and glycosylated with a levulinate ester and then fluorinated. This compound is highly pure and can be synthesized on custom order.</p>

<p>GT1b (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b is one of the major gangliosides in neuronal and glial membranes, it interacts with the myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishik,i 1996), as well as for viruses, a few examples include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).</p>

<p>Lewis A trisaccharide methyl glycoside is a sugar that is synthesized by the chemical modification of an oligosaccharide. The methyl glycoside is then fluorinated and reacted with a complex carbohydrate to produce Lewis A trisaccharide methyl glycoside. It has CAS No. 186315-40-2, which identifies it as a synthetic compound. This product has high purity, and can be custom synthesized to meet your needs. It is also available in both a glycosylated and non-glycosylated form.</p>

<p>Shortest chain oligosaccharide that can be classified as a maltodextrin. A component of liquid glucose (a commercial sweetener composed of glucose, maltose, maltotriose and maltotetrose).</p>

<p>Isolated from the products of the acid reversion of D-mannose</p>

<p>The modification of this product has been completed with a high level of purity and the CAS number is 57-49-6. It is an oligosaccharide that is a complex carbohydrate. This product can be synthesized through custom synthesis and it is a synthetic product. It is classified as a monosaccharide, methylation, glycosylation, and polysaccharide. The chemical formula for this compound is C12H14O11. This compound has been fluorinated to increase its solubility in water.</p>

<p>A rare sugar, prebiotic fibre and inhibitor of α-glucosidases. It inhibits animal-, plant- and microorganism-derived α-glucosidases I. In rodent models for diabetes, it ameliorates arachidic acid-induced liver injury and reduces hepatic inflammatory markers.</p>

<p>Substrate for fucosidase; used in infant formula; improves health in infants</p>

<p>Sialyl Lewis X (SLeX) is a carbohydrate antigen, related to cell adhesion and it has been shown that inhibition of SLeX synthesis leads to decreased adhesion of trophoblast cells to endometrial epithelial cells (Collins, 2006). Sialyl Lewis X is displayed on the terminus of glycolipids that are present on the surface of white blood cells and it has been shown that SLeX has an important role in inflamation processes. The inital adhesion of white blood cells to a site of injury is mediated by E-selectins which are specific for SLeX. Cell-cell recognition between leukocytes and endothelial cells in blood is believed to occur in part through interactions between lectins and oligosaccharide ligands. SLeX is frequently expressed in human cancer cells and primary tumors. It has been demonstrated that SLeX was involved in the adhesion of tumor cells to vascular endothelium. The potential role of SLeX in the tumor metastatic process has been supported by several clinical studies (Liang, 2016).</p>