Oligosaccharides

<p>NGA3 N-Glycan is a high purity, custom synthesis, sugar-containing glycoprotein. It is synthesized by Click modification of the glycopeptide backbone with a fluorinated amino acid and then glycosylated with an acetylated sugar. The acetylation of the sugar allows for selective labeling of the glycan. This product can be used in research applications such as Fluorination, Glycosylation, Synthetic, Methylation, Modification and Carbohydrate. It has CAS No. 110387-63-8 and is available in both Monosaccharide and Oligosaccharide form.</p>

<p>Synthesized by the action of zinc chloride on tetra-O-acetylmannose and 1-chloro-3,4,6- tri-0-acetylmannose.  Isolated from partial acetolysates of baker's yeast mannan and Saccharomyces rouxii mannan.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarotetraose is reported to have potential for novel cosmeceuticals.</p>

<p>3-O-(2-Acetamido-2-deoxy-b-D-galactopyranosyl)-D-galactopyranose is a sugar molecule with biological properties such as lectin, terminal sugar, and carbohydrate. It is a specific sugar for the blood group B. This sugar is also used in assays for pneumococcus, which is a bacterium that can cause pneumonia. 3-O-(2-Acetamido-2-deoxy-b-D-galactopyranosyl)-D-galactopyranose is oxidized by enzymes called oxidases to form 3,4,6 -triacetamido galactose (3TAG) and 3,4,6 -triacetamido glucose (3TG). The disaccharide residues are then hydrolyzed into monosaccharides by glycoconjugates and polyvalent glycosidases.</p>

<p>Tetra-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-a-D-glucopyranosyl)-b-D-galactopyranoside is a polysaccharide that is synthesized by the methylation of 1,3,4,6-tetra-O-benzyl -2,3,4,6 tetra - O - benzyl - a - D - glucopyranoside. It can be used to modify proteins and oligosaccharides. This product is custom synthesized and has high purity.</p>

<p>Substrate for glucoamylases; derived from pullulan using pullulanase</p>

<p>This is a custom synthesis of a complex carbohydrate. The CAS number is not available and the polysaccharide has been modified. It has been glycosylated, methylated, and fluorinated. It is high purity and the sugar sequence is a custom synthesis.</p>

<p>The blood group antigen Sialyl Lewis X (SLeX) is an oligosaccharide which plays a vital role in cell-cell recognition processes. SLeX is a terminal residue on glycolipids that are present on the surface of white blood cells and plays a key role in inflamation processes (Collins, 2006). The inital adhesion of white blood cells to a site of injury is mediated by E-selectins which specifically interact with SLeX. Cell-cell recognition between leukocytes and endothelial cells in blood is believed to occur in part through interactions between lectins and oligosaccharide ligands (Munro, 1992).</p>

<p>Derived from pullulan using pullulanase</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-b-lactosyl azide is a custom synthesis of a carbohydrate that has been modified by the addition of acetyl groups to one end and the attachment of an azide group to the other. The synthesis of this compound has been completed in high purity and is available for purchase. This compound is a complex carbohydrate that is a sugar that can be modified by fluorination. It is also an oligosaccharide or polysaccharide with saccharide units.</p>

<p>1,2,3,6-Tetra-O-acetyl-4-O-[2,3,6-tri-O-acetyl-4-O-(2,3,4,6 tetra-O-acetyl bDglucopyranosyl)-bDglucopyra nosyl]-bDthioglucopyranose (1) is a sugar with the chemical formula C36H62N8O24. It was first synthesized by the group of L. W. F. Heckel in 1956 and its structure was elucidated by X. Miettinen in 1957. 1 is a complex carbohydrate with a glycosidic linkage to 4 as well as an acetate ester at position 6. The compound has been modified with methyl groups at positions 2 and 3 to form 1,2,3,6 tetra O acetyl 4 O methyl 2 O methyl 3 O methyl 6 O eth</p>

<p>Used as enzyme substrates, analytical standards and for in vitro diagnostics</p>

<p>Cellotriose is a bifunctional sugar that can be chemically converted to cellobiose and D-cellopentaose. Cellotriose is a component of cellulose, which is the most abundant biopolymer on Earth. Cellotriose is a source of chitin, which is a major component of the exoskeleton of insects and crustaceans. The molecule has been observed using atomic force microscopy to have an amphiphilic nature, in that it has both hydrophobic and hydrophilic regions. Cellotriose has been synthesized in the laboratory for use as an artificial sweetener, but it does not taste as good as sucrose because it lacks the sweetness profile. When heated, cellotriose undergoes a color change from yellow to blue-green due to its ability to form hydrogen bonds with oxygen molecules. This property can be used as a colorimetric test for cellulase activity in solutions.</p>

<p>N-Acetylneuraminic acid-OVA refers to ovalbumin that has been conjugated with N-acetylneuraminic acid (Neu5Ac), a type of sialic acid. Sialic acids are important components of glycan structures and play various roles in biological processes, such as cell-cell interactions, immune response, and pathogen recognition. Conjugation of ovalbumin with N-acetylneuraminic acid can be used as a tool to study sialic acid-mediated biological phenomena or as an immunogen to elicit a specific immune response.</p>

<p>6-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactopyranose is a disaccharide that has been shown to have anti-inflammatory activities. It contains an acetamide group and a hydroxy group. The acetamide group is substituted by a hydroxy group, which may be responsible for its anti-inflammatory activity. 6-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactopyranose has also been shown to inhibit the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNFα) and interleukin beta (ILβ).</p>

<p>Benzyl 4-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a Glycosylation product that is custom synthesized to order. It is an oligosaccharide, which is synthesized by the modification of monosaccharides with other saccharides. This product has been fluorinated and acetylated at its C4 position and methylated at its C6 position. This compound has CAS No. 18404-72-3 and can be used as a sugar in the synthesis of complex carbohydrates or as a component of polysaccharides.</p>

<p>Isolated from ivory-nut mannan hydrolysates</p>

<p>N-Acetyl-D-lactosamine (LacNAc) is a natural structural element in a variety of glycoconjugates, found in milk, urine, meconium and glyciproteins. It’s a substrate for galactosidases, fucosyltransferases, and sialyltransferases. This LacNAc is also useful as a lectin inhibitory sugar and for characterizing lectins.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-acetyl-4-O-(2,4,6-tri-O-acetyl-3-O-allyl bDgalactopyranosyl)-bDglucopyranoside is a modification of an oligosaccharide. It is a high purity and custom synthesis. This product can be found under CAS No. 807827-28-0.</p>

<p>GM1 pentasaccharide biotin (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue and biotin linked β to position 1 on the reducing glucose moiety (Ledeen, 2009). The parent ganglioside GM1 is abundant in all mammalian brains, where it covers 10%-20% of the total ganglioside mixture. It is found in epithelial membranes and is a key element for bacterial toxicity and viral infection as it is the intestinal receptor for cholera toxin the B-subunits of heat-labile toxin, rotavirus, and simian virus 40. GM1 ganglioside functions as a neurotrophic and neuroprotective compound and has been used therapeutically for diabetic and peripheral neuropathies. GM1 ganglioside also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>