Oligosaccharides

Used as enzyme substrates, analytical standards and for in vitro diagnostics

<p>The blood group B type III/IV linear trisaccharide is a synthetic oligosaccharide. The methylation of the saccharide and click modification of the polysaccharide molecule allow for fast, efficient synthesis. This product has been custom synthesized to be free of impurities, high in purity, and available in glycosylation form. It can be modified with fluorination or other modifications to meet your needs.</p>

<p>2-O-(2-O-(a-D-Mannopyranosyl)-a-D-mannopyranosyl)-a-D-mannopyranose is an oligosaccharide that is synthesized by the glycosylation of a D-mannose with 2,3,4,6-tetra‑O‑benzoyl‑beta‑D‑glucuronic acid. This product is available in custom synthesis and can be modified to order. It has been shown to be highly pure and can be used for a variety of applications including glycosylation reactions, methylations, fluorinations, click modifications, and complex carbohydrate studies.</p>

<p>GA1-ganglioside is also known as asialo-GM1 ganglioside. Autoimmune responses to GA1 ganglioside and high titers of anti-GA1 antibodies have been associated with neuromotor disorders, such as, motor neuron disease, multifocal motor neuropathy, and Guillain-Barré syndrome (Kolter, 2006). Anti-GA1 antibodies are also associated with Borrelia burgdorferi infection and Lyme disease (Djellaoui, 2016).</p>

Monofucosyl (1-3)-iso-lacto-N-octaose is an HMO oligosaccharide.

<p>D-Maltose monohydrate is a glycosylation product of maltose. It is a complex carbohydrate that has been methylated, fluorinated, and modified with Click chemistry. D-Maltose monohydrate has the CAS number of 3647-20-3 and can be custom synthesized to meet your specifications. This product is free from endotoxins and can be made in high purity.</p>

<p>The structure of GD2-oligosaccharide-sp-biotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) with two sialic acids linked (β-2,3/β-2,8) to the central galactose residue and biotin attached to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy.</p>

<p>Blood group antigen conjugated to spacer and biotin</p>

<p>Lewis Y-O-(CH2)8-biotin is a carbohydrate with the chemical formula (CHO)(CO)3OH. It is a methylated and glycosylated oligosaccharide that has been custom synthesized for use in biotechnology applications. Lewis Y-O-(CH2)8-biotin has been fluorinated at the C5 position to improve its stability and prevent hydrolysis, which may be due to its high purity. This carbohydrate is not commercially available and must be custom synthesized.</p>

<p>Fleetamine is a piperidine compound that has been shown to be an inhibitor of the enzyme glycosylation. Inhibitors of glycosylation are useful for treating diseases such as diabetes and Alzheimer's disease. It is thought that Fleetamine may inhibit human glycosylating enzymes, such as glucosyl transferase, which catalyzes the addition of a glucose molecule to a protein. This inhibition prevents the formation of oligosaccharides and glycoconjugates, which are necessary for proper functioning of cells.</p>

<p>Non-reducing disaccharide; mildly sweet energy source; protein stabilizer</p>

Heparin is a complex carbohydrate that has been modified by the addition of a sugar and a sulfate group. It is used in the treatment of thrombosis, deep vein thrombosis, pulmonary embolism, and other blood clots. Heparin disaccharide IV-S disodium salt (HDS) is an intravenous form of heparin that consists of sodium salts of two saccharides: heparin disaccharide and sodium disulfate. HDS has been shown to be more potent than unfractionated heparin in animal models, as well as being more effective in preventing clot formation in humans. This drug also exhibits less frequent side effects such as skin rash, itching, or hives.

<p>Sialyllacto-N-fucopentaose VI is a synthetic, high-purity, complex carbohydrate that has been modified with methylation and fluorination. It is a glycosylate oligosaccharide with a molecular weight of about 4500. Sialyllacto-N-fucopentaose VI can be custom synthesized to order and is available in both powder and solid forms.</p>

<p>Glycyl-monosialyllacto-N-neohexose I is a monosaccharide that is used as a building block in the synthesis of complex carbohydrates. It is custom synthesized and purified to high purity. This product can be fluorinated and methylated, which allows for the attachment of glycosyl groups. Glycyl-monosialyllacto-N-neohexose I is also a sugar with a CAS number. It has an average molecular weight of 137.14 g/mol and is made up of three atoms: carbon, hydrogen, and oxygen.</p>

<p>NGA2F Glycan is a complex carbohydrate that is synthesized by the enzymatic transfer of an N-acetylgalactosamine (GalNAc) residue to a serine or threonine residue on protein. It is modified with methylation, Click modification, and fluorination. NGA2F Glycan has two binding sites for 2-AB labelled monosaccharides. The glycosylation site is located at the non-reducing end of the molecule, while the oligosaccharide site is located at the reducing end of the molecule.</p>

A3 Glycan, 2-AB labelled is a complex carbohydrate. It is synthesized by the methylation and glycosylation of the A3 sugar, which is a monosaccharide. The A3 Glycan, 2-AB labelled has a CAS No. of 711-81-2 and is a synthetic oligosaccharide with high purity. Its chemical formula is C6H8O5N2O2 and its molecular weight is 192.19 g/mol. The A3 Glycan, 2-AB labelled has an MW of 192.19 g/mol and an MW of 643 Da (1). It also contains one saccharide unit that consists of two bonded monosaccharides: fructose and glucose. A3 Glycan, 2-AB labelled CAS No.: 711-81-2 Molecular Formula: C6H8O5N2O2 Mole

<p>GloboH-pentanyl backbone for incorporation onto peptide or conjugated to protein</p>

<p>Thiocellotetraose is a glycosylation product of cellulose. It is a complex carbohydrate that is similar to other saccharides. Thiocellotetraose can be obtained by methylation, click modification, and fluorination. The monosaccharide units in thiocellotetraose are glucose and mannose. This product can be custom synthesized to meet your specific requirements for purity and CAS number.</p>

<p>Glucomannan oligosaccharides are modified polysaccharides of plant origin. They are not digested in the small intestine and are instead fermented by the large intestine to produce short-chain fatty acids. This is a novel approach to weight control. The modified monosaccharide backbone provides for a more complex carbohydrate than found in other dietary fibers, and this complex carbohydrate is resistant to digestion by mammalian enzymes. Glucomannan oligosaccharides can be used as a replacement for high-calorie sweeteners in many food applications and as a bulk laxative.</p>

Food additive; soil suspension polymer in detergents; thickening agent