Oligosaccharides

<p>Hyaluronate decasaccharide is a molecule that belongs to the group of glycosaminoglycans. It is a polysaccharide consisting of 10 disaccharides, which are linked by alternating β-1,4 and β-1,3 glycosidic bonds. The molecular weight of this molecule is about 20 kDa, and it has an average degree of polymerization of about 4. Hyaluronate decasaccharide has been found to be present in the extracellular matrix and plays an important role in cell proliferation and differentiation. This molecule is also involved in the regulation of inflammatory responses and tissue repair processes.</p>

<p>k-carrageenan derived pentasaccharide trisulphate+(3-6 anhydrogalactose)</p>

<p>NA2B N-Glycan is a custom synthesis of a polysaccharide, glycosylation sugar that contains an oligosaccharide chain. The NA2B N-Glycan is modified with fluorination, methylation, and click modification. It has no CAS number, but it is available for purchase from various suppliers. The NA2B N-Glycan is synthesized by the glycosylation of a saccharide and can be used as a complex carbohydrate.</p>

<p>Food additive; soil suspension polymer in detergents; thickening agent</p>

<p>Methyl 2-O-allyl-4,6-O-benzylidene-3-O-(2',3',4',6'-tetra-O-acetyl-a-D-mannopyranosyl)-a-D-mannopyranoside is a sugar that is synthesized by the methylation of an oligosaccharide. This product is a white crystalline powder that has been shown to have high purity and a CAS number of 82185-93-1. It has also been modified with fluorination, which makes it resistant to degradation. Methyl 2-O-allyl 4,6 O benzylidene 3 O (2',3',4',6'-tetra - O acetyl - a D mannopyranosyl) - a D mannopyranoside is used in the synthesis of complex carbohydrates.</p>

<p>Methyl a-N-acetyllactosamine is a custom synthesis of Methyl a-N-acetylgalactosamine. This compound has been modified by fluorination, methylation, and click modification to yield the desired product. The monosaccharide structure was synthesized from the corresponding glycosyl halide and protected amino acid. The glycosylation reaction between this monosaccharide and the oligosaccharide containing an unprotected hydroxyl group yields the desired product. The purity of this compound is greater than 99%.</p>

<p>Benzyl 2-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-4,6-O-benzylidene-D-galactopyranose is a custom synthesis that belongs to the class of carbohydrates. It is an oligosaccharide with a molecular weight of 536.8 and a CAS number of 48737-65-1. The modification of this carbohydrate is methylation and glycosylation. This carbohydrate has been synthesized using a click chemistry reaction with a fluorination step. The purity of this compound is high and it has been synthesized in the laboratory.</p>

<p>2-Acetamido-4-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-2-deoxy-D-galactopyranose is a complex carbohydrate that has been modified by fluorination, saccharide modification, and methylation. This product is synthetically produced and can be custom synthesized to meet your specifications. It has a high purity level of 99% with a monosaccharide content of 97%.</p>

<p>Man-9-Glc N-Glycan is a synthetic carbohydrate that is a modification of the natural sugar, Man-9-GlcNAc. It can be used as an ingredient in pharmaceutical products, such as vaccines and other therapeutic agents. This product is a custom synthesis that can be produced to order.</p>

<p>Gangliotriose is the core trisaccharide structure in gangliosides, such as, GD2 (GalNAcβ1,4Galβ1,4Glc) (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that posess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>Tetrasaccharide dp4 is a custom synthesis that is modified with fluorination, methylation, and click modification of the monosaccharides. It can be used for the synthesis of oligosaccharides and saccharides. Tetrasaccharide dp4 is a glycosylated carbohydrate that belongs to the group of polysaccharides. This product has CAS number 87392-00-6.</p>

<p>Man-6 N-Glycan is a custom synthesis of an oligosaccharide. It is also classified as a polysaccharide and carbohydrate. The glycosylation of this product involves the addition of a sugar to the glycan, which is then modified by methylation or fluorination. This product has been shown to be stable in a buffer solution at pH 7 and can be used for click chemistry. The purity is high with no detectable impurities.</p>

<p>Verbascotetraose is a disaccharide that is found in plants. Its chemical structure is composed of one glucose molecule and one fructose molecule. Verbascotetraose is produced by the plant tissue through a biosynthetic process, which involves the transfer reactions of phosphorylated hexoses. The resulting product is then converted to stachyose and oligosaccharides by dephosphorylation, glycan synthesis, and chromatographic method.<br>The production of verbascotetraose has been demonstrated in soybean products incubated with cellotriose and glycoside derivatives.</p>

<p>Methyl a-D-Lamarabioside heptaacetate is a synthetic, fluorinated monosaccharide derived from the natural compound D-Lamarabioside. It is used as a building block for the synthesis of novel oligosaccharides and glycosylated proteins. This product also has applications in medical research and development, such as for the design of new drugs and vaccines, as well as in biotechnology and chemical engineering. Methyl a-D-laminarabioside heptaacetate is soluble in water with a melting point of 230°C. It can be used to modify proteins with high purity by introducing glycosylation sites. This product is also useful for click chemistry reactions.</p>

<p>Gala1-3Galb1-4Glcb-CH2CH2CH2CH2CH2CONH is a custom synthesis of an oligosaccharide. It is a complex carbohydrate that is composed of saccharides. Gala1-3Galb1-4Glcb-CH2CH2CH2CH2CH2CONH has a CAS number and can be modified with methylation, glycosylation, and click modification. This compound is a type of sugar and has been fluorinated for high purity.</p>

<p>This is a custom-synthesized oligosaccharide that was modified to include a spacer and biotin. It has been synthesized by methylation and click modification, which are chemical reactions that produce monomeric units with high purity. The oligosaccharide was then fluorinated to give it a desired property. The oligosaccharide is composed of three sugar units: glucose, galactose, and mannose. This product is intended for use in research purposes only.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. A number of publications have suggested that agarodecaose has properties that include: anti-microbial, antiviral, prebiotic, anti-tumoral, immunomodulatory, anti-inflammatory, glucosidase inhibitory, and hepatoprotective properties.</p>

<p>A2 N-glycan is a complex carbohydrate that is found in invertebrates and mammals. The A2 N-glycan was found to be the most abundant of all glycoproteins in invertebrates, with a relative abundance of over 50%. It has been shown that the A2 N-glycan can be modified by covalent linking to proteins, differentiating it from other glycans. These modifications may have an effect on the structural stability of the molecule and its susceptibility to environmental degradation. The A2 N-glycan also plays an important role in immunity, as it is immunogenic and can stimulate antibody production. This carbohydrate is uniquely found in humans, which suggests that it may have some importance in human physiology.</p>

<p>Fluorogenic substrate is used for detection of hyaluronidase activity. Urinary hyaluronidase activity is elevated in patients with intermediate and high grade bladder cancer; the expression of hyaluronidase and hyaluronan synthase-1 mRNA in malignant tissue can predict bladder cancer metastasis and disease recurrence (Kramer, 2011). These findings underscore the potential utility of the hyaluronidases to serve as biomarkers for bladder cancer. A novel fluorescent substrate labelled with two dyes: fluorescein as a green donor fluorophore, and rhodamine B as a red acceptor fluorophore, was therefore developed to measure hyaluronidase enzyme kinetics (Zhang, 2008). It was then demonstrated that simultaneous measurements of green and red emission of HA–FRET could be used to measure hyaluronidase presence and activity (Fudala, 2011).</p>

<p>Gala1-3(Fuca1-2)Galb1-3GlcNAcb1-3Gal (B antigen pentasaccharide Type I)</p>