Polycyclic Compounds

<p>Please enquire for more information about 6-Bromo-4-methoxy-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Please enquire for more information about 6-Benzyloxy-5-methoxyindole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Pentyl-1H-indole-2,3-dione is a synthetic cannabinoid that is used as a recreational drug. It has been shown to be thermally labile and can decompose at high temperatures. 1-Pentyl-1H-indole-2,3-dione is an acidic compound with a melting point of 79°C. The compound is also oxidant and therefore can react with other compounds to create new substances. This reaction can be accelerated by light or heat, which may result in the formation of hazardous products such as naphthalene.</p>

<p>Methyl (1R,2S,3S)-8-(3-Fluoropropyl)-3-(4-Iodophenyl)-8-Azabicyclo[3.2.1]Octane-2-Carboxylate is a potent dopamine receptor agonist with a high affinity for the D2 and D3 receptors in the brain. It has been shown to have antiparkinsonian effects in animal models of Parkinson's disease by increasing dopamine levels in the prefrontal cortex and striatum. This drug has also been shown to be effective in clinical studies for the diagnosis of Parkinson's disease. Methyl (1R,2S,3S)-8-(3-Fluoropropyl)-3-(4-Iodophenyl)-8-Azabicyclo[3.2.1]Octane-2-Carboxylate binds to both dopamine and serotonin receptors, which may account for its therapeutic effects on Parkinson</p>

<p>Please enquire for more information about Methyl 6-Bromo-1-Methyl-1H-Indole-2-Carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,4-Dioxo-9-(phenylmethyl)-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile is an aliphatic compound that is used in the synthesis of formaldehyde and amines. It has been shown to react with formaldehyde to produce a mixture of aliphatic amines. This reaction can be used for the production of commercial products such as dyes and pharmaceuticals.</p>

<p>4-fluoro-1-methyl-1,4-diazoniabicyclo[2.2.2]octane (ditetrafluor) is a fluorine containing compound that can be used to treat cancer cells. It is a chiral molecule with four stereoisomers, two of which are active against cancer cells and the other two are inactive. Ditetrafluor has been shown to have antiviral activity against influenza A virus by inhibiting viral replication, but it does not have any effect on the common cold virus. This drug is also able to inhibit syncytia formation in cultured cells and has been shown to be effective in treating malaria caused by Plasmodium falciparum.</p>

<p>(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is an antimicrobial agent that inhibits bacterial growth by binding to the penicillin binding protein (PBP), which prevents the synthesis of peptidoglycan. This drug has shown effectiveness against gram positive bacteria, including aerobacter aerogenes, as well as infectious diseases in wastewater treatment plants. It has also been demonstrated to be effective in experimental models of infection due to high resistance and cell signaling pathways. The reaction solution was analyzed by plasma mass spectrometry.</p>

<p>1-Methylimidazole is a compound with the molecular formula CH3N2H. It is soluble in water, but insoluble in organic solvents. 1-Methylimidazole has been found to bind to human serum and p-nitrophenyl phosphate. The fluorescence of 1-methylimidazole is quenched by hydrogen bonding interactions, which are the same as those that occur in natural compounds such as hemoglobin and chlorophyll. The nitrogen atoms on the surface of 1-methylimidazole can be detected using infrared spectroscopy. This method can also be used to analyze group P2 molecules, such as benzene, phenol, and cyclohexane.</p>

<p>3-Hydroxyisoquinoline is a non-nucleoside inhibitor of cyclic nucleotide phosphodiesterase (cNMP) that is used in the treatment of nervous system diseases. 3-Hydroxyisoquinoline has been shown to have an inhibitory effect on cyclic nucleotide phosphodiesterase and can be used for the treatment of neurological disorders such as Parkinson’s disease, Alzheimer’s disease, and epilepsy. It also has anti-inflammatory properties and can be used to treat pain. 3-Hydroxyisoquinoline has a photoelectron spectrum that peaks at 5.6 eV, with a strong absorption band at 2.1 eV due to hydrogen bonding. This compound is also able to absorb radiation in the form of light emission with an emission peak at 4.8 eV, with a maximum intensity around 830 nm and a half-life of 0.2 s. 3-Hydroxyisoquinoline is able to</p>

<p>Murralongin is a natural compound that falls under the category of sesquiterpenes, a class of terpenoids characterized by their three isoprene units. It is derived from the leaves and stems of the plant Eremophila mitchellii, a species known for its rich diversity of bioactive compounds often utilized in traditional medicine. The primary mode of action of Murralongin involves modulation of specific enzymatic pathways, potentially influencing a range of biological processes, including anti-inflammatory and antimicrobial activities.</p>

<p>2-Hydroxy-4-methylquinoline is an organic compound that has a chelate ring. It is soluble in deionized water and reacts with metal ions to form a fluorescent product. The molecule also has antibacterial activity, which may be due to its ability to inhibit the growth of bacteria by acting as a metal ion chelator. 2-Hydroxy-4-methylquinoline can react with halides and ammonium persulfate to form isomeric products, such as 4,5-dihydroxyquinoline, which have been shown to have antimicrobial properties. 2-Hydroxy-4-methylquinoline can also react with phosphorus oxychloride and alkylating agents such as chloroethane or chloroform to form substituted derivatives.</p>

<p>Please enquire for more information about Moluccanin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Methyl-1H-indole-3-carbohydrazide (MZ) is a potential anticancer drug that inhibits the growth of cancer cells. It binds to the colchicine binding site on the DNA, which prevents doxorubicin from binding and causing damage to the DNA. MZ has been shown to be effective against breast cancer and has been shown to inhibit tumor growth in mice by targeting cancer cells lines. MZ also inhibits proliferation of MDA-MB-231 cells in culture, as well as inhibiting cell cycle progression, leading to apoptosis. The molecular docking studies show that 1MZ binds to colchicine site on DNA with high affinity and specificity.</p>

<p>Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate (tBAA) is a heterocycle that has been modified to enhance its pharmacokinetic properties. Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate was designed to be metabolically stable and have a high bioavailability and isosteric properties with phosphatidylinositol, which it uses as a substrate in the catalytic cycle. This modification also increased tBAA's stability in vivo, leading to an increase in efficacy. The covalent attachment of the phenyl ring on the tertiary amine nitrogen of tBAA provides additional protection against hepatic metabolism by CYP450 enzymes, making it more potent than other compounds with similar structures that are not covalently attached to the amine group.</p>

<p>3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium is an anticoagulant compound, which is a synthetic derivative of coumarin. It is primarily sourced via chemical synthesis in laboratory settings. Its mode of action involves inhibiting the synthesis of vitamin K-dependent clotting factors, specifically factors II, VII, IX, and X. This inhibition impairs blood coagulation, leading to uncontrolled bleeding.</p>

<p>4,7,13,16,21-Pentaoxa-1,10-diazabicyclo[8.8.5]tricosane (POD) is a nitrogen containing heterocycle that is used as a fungicide and insecticide. POD has significant antifungal activity against various species of fungi such as Trichophyton mentagrophytes and Candida albicans. It also inhibits the growth of some Gram-positive bacteria such as Clostridium botulinum. The compound may be used to treat conditions associated with elevated blood pressure by inhibiting the conversion of tyrosine to dihydroxyphenylalanine (DOPA). POD forms stable complexes with metal hydroxides in the presence of water and hydrochloric acid, which are important intermediates for chemical reactions. The frequency shift of positron emission in POD is due to the electron capture during positron annihilation.</p>

<p>1,3-Dipropyl-7-methylxanthine is a xanthine compound that is structurally related to caffeine. It has been shown to have an inhibitory effect on the production of reactive oxygen species and cytosolic calcium levels in primary cells, as well as a nonselective adenosine receptor antagonist activity. It has also been shown to antagonize the effects of adenosine receptors, p2 receptors, and p2y receptors. This drug is used for the treatment of basophilic leukemia.</p>

<p>Indole-3-acetyl-L-glutamic acid is an endogenous substance that is found in plants. It is the conjugated form of indole-3-acetaldehyde and L-glutamic acid. Indole-3-acetylglutamic acid has shown to have antioxidant potential and can be used to regulate plant growth, as well as protect against environmental stresses. Indole-3-acetylglutamic acid also has a role in regulating the production of other hormones, such as ethylene and auxin, which are involved in plant growth regulation.</p>

<p>5,7-Dichloro-8-hydroxyquinoline (5,7-DC8HQ) is a mitochondrial drug that inhibits mitochondrial functions by binding to the ATP synthase. It has been shown to be effective against bacteria resistant to antimicrobial agents in vivo and also showed genotoxic activity in vitro. 5,7-DC8HQ binds to the magnesium site of the ATP synthase protein and prevents the formation of an intramolecular hydrogen bond, which leads to inhibition of ATP synthesis. This drug has also been shown to cause membrane potential depolarization in mitochondria.</p>

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<p>1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline is a chemical compound that has been used as an intermediate in the synthesis of pharmaceuticals. It is also a useful building block for the production of other chemicals. This compound is soluble in water. 1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline has shown to be a versatile and high quality reagent with many research applications.</p>

<p>Please enquire for more information about 9-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Xanthoxyletin is a coumarin, which is a type of natural organic compound commonly found in plants, particularly in the Rutaceae family. It is sourced from various plant species, including Zanthoxylum, known for their ethnobotanical uses. Xanthoxyletin functions primarily through its biochemical activity, including the inhibition of certain enzymes and modulation of cellular pathways that influence its pharmacological effects.</p>

<p>Pranferol is a phytochemical compound, which is derived from natural plant sources. It possesses unique immunomodulatory properties, affecting cellular pathways that regulate immune responses. The bioactive components in Pranferol interact with specific receptors on immune cells, modulating signaling cascades and gene expression to enhance or suppress specific immune functions depending on the physiological context.</p>

<p>3-Chloro-7-nitro-1H-indole is a chemical compound that has been shown to have antitumor activity in clinical trials. It is catalysed by the addition of chloride ions to the nitro group, yielding an aminocarbonyl intermediate. This intermediate reacts with hydrogen chloride to form a chlorinating agent that can react with DNA and protein bases. The chlorinating agent has been shown to be efficient in screening for anticancer drugs. 3-Chloro-7-nitro-1H-indole is currently being tested for efficacy against colon carcinoma cells and human colon carcinoma xenografts.</p>

<p>1,1'-Dimethyl-4,4'-bipyridinium dichloride hydrate is a bipyridine with a divalent chloride. It has been shown to have synergic effects in the presence of dextran sulfate and paraquat. This compound has good photochemical properties, which are used for wastewater treatment and surface methodology. 1,1'-Dimethyl-4,4'-bipyridinium dichloride hydrate also has toxicological studies that show it does not cause any cellular toxicity or mitochondrial membrane potential changes. It also reduces potassium dichromate toxicity in glomerular filtration rate studies. This compound can be used as an analytical method for other bipyridines.</p>

<p>Graveolone is a bioactive compound that functions as a plant defense enhancer, which is derived from certain plant species known for their antimicrobial properties. Its mode of action involves the activation of multiple signaling pathways that bolster the plant's innate immune response. By enhancing the synthesis of defensive proteins and secondary metabolites, Graveolone effectively fortifies plants against pathogenic challenges and abiotic stresses.</p>

<p>Please enquire for more information about 2-Oxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Please enquire for more information about Peuarin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Isoquinolinecarboxylic acid is a molecule with a reactive group that can form cyclic structures. It has been shown that 3-Isoquinolinecarboxylic acid is an apoptotic agent in human macrophages and induces the release of picolinic acid from these cells. This molecule also has a high affinity for α7 nicotinic acetylcholine receptors, which are present on the surface of nerve cells. 3-Isoquinolinecarboxylic acid can be synthesized by condensing picolinic acid, an aromatic aminoacid, with an appropriate amine. The synthesis of this heterocycle is catalyzed by an enzyme called quinolinate synthase. The product of this reaction is oxidized to form 3-isoquinolyl carboxylic acid. The final step in the synthesis involves the oxidative cleavage of a disulfide bond using hydrogen peroxide, yielding 3-isoquinoly</p>

<p>Tetrahydroquinoline-3-carboxylic acid is a crystalline, water-soluble compound. It is an intermediate in the synthesis of l-phenylalanine, paraformaldehyde and formaldehyde. Tetrahydroquinoline-3-carboxylic acid can be hydrolyzed to produce formic acid and hydrogen chloride. This product is also optically active and can be used as an indicator for hydroiodic acid.</p>

<p>Benazeprilat is a prodrug that is metabolized to enalaprilat, its active form. It is an inhibitor of angiotensin-converting enzyme (ACE) and has been shown to be effective in the treatment of heart failure. It has also been shown to inhibit ACE activity in vitro and in experimental models of congestive heart failure. Benazeprilat binds to the active site on the ACE molecule and inhibits the conversion of angiotensin I into angiotensin II, which causes vasoconstriction and stimulates aldosterone release from the adrenal cortex. This drug also has effects on energy metabolism by stimulating beta oxidation, which leads to increased levels of ketone bodies in blood plasma.</p>

<p>5-Bromo-1H-indole-2-carboxylic acid methyl ester is a drug that belongs to the class of carboxylates. It has been shown to inhibit the growth of tumor cells in vitro and in vivo. The antitumor activity of this compound may be due to its ability to stabilize planar indole moieties, which are cytotoxic. 5-Bromo-1H-indole-2-carboxylic acid methyl ester interacts with other molecules through intermolecular interactions and can form an indole ring system that has a trifluoromethyl group and a carboxylate group in its structure.</p>

<p>Please enquire for more information about (1-Chloroisoquinolin-4-yl)boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Boc-(3S)-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylic acid is a synthetic opioid that is chemically related to morphine. It binds to the δ opioid receptor and has a clinical development in the treatment of pain. The drug has been shown to inhibit the binding of gtpγs, which leads to the suppression of neuronal activity. Boc-(3S)-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylic acid also has low molecular weight and low toxicity.</p>

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<p>Umbelliprenin is a naturally occurring prenylated coumarin, which is primarily isolated from plants in the Apiaceae family. These plants are rich sources of various biologically active compounds. The mode of action of umbelliprenin is attributed to its ability to modulate multiple cellular pathways, including apoptosis and cell cycle arrest. This modulation is largely due to its interaction with reactive oxygen species and various signaling molecules within the cell.</p>

<p>Please enquire for more information about 1-(2-Methoxyethyl)-1H-indole-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-Bromoisoquinoline is a bifunctional alkylating agent that is used to synthesize esters and amides. It is commonly used for the synthesis of amino acids, peptides, and other biologically active molecules. 8-Bromoisoquinoline has been shown to have a synergistic effect with hydroxyalkyl carbamates, which may be due to its ability to form an ionic bond with the carboxylic acid in these compounds. This chemical can also react with nitro groups and serve as a chlorinating agent, as well as react with anions such as phosphate and acetate. 8-Bromoisoquinoline can be synthesized by reacting ethyl bromoacetate with tetrahydroisoquinolinium chloride in hydrochloric acid or isopropyl alcohol.</p>

<p>Please enquire for more information about Ethyl 7-Methoxy-1H-Indazole-3-Carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Neobyakangelicol is a phytochemical compound, which is a natural product derived from various plant species. Its source is predominantly the roots of certain medicinal plants that are known for their array of bioactive constituents. The mode of action of Neobyakangelicol primarily involves interacting with specific biochemical pathways, potentially including modulation of enzyme activity or receptor binding, which could result in diverse pharmacological effects.</p>

<p>Indole-3-acetyl-L-phenylalanine is a plant growth regulator that inhibits the transport of auxin in the plant. It is used as a regulatory agent to inhibit the growth of plants by interfering with their natural regulatory mechanisms. Indole-3-acetyl-L-phenylalanine is an effective inhibitor of auxin transport and has been shown to have an inhibitory effect on plant growth. This compound also binds to acid conjugates, which are found in plants, and blocks their ability to bind to auxin receptors, preventing them from activating the cell's responses. This inhibition leads to decreased cell division and reduced root growth.</p>