Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1566 products of "Cytoskeletal Signaling"
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SGC-AAK1-1
CAS:SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.
Formula:C21H25N5O3SPurity:99.68%Color and Shape:SolidMolecular weight:427.52CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formula:C33H34N7Na2O7PPurity:98.87%Color and Shape:SolidMolecular weight:717.63Talquetamab
CAS:Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.Color and Shape:LiquidMolecular weight:144.59 kDaDarifenacin hydrobromide
CAS:Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Formula:C28H31BrN2O2Purity:99.75% - >99.99%Color and Shape:SolidMolecular weight:505.457-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formula:C10H12N2O5SPurity:91.05%Color and Shape:White Solid PowderMolecular weight:272.28Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formula:C17H20ClNOPurity:99.32% - 99.85%Color and Shape:SolidMolecular weight:289.8TINK-IN-1
CAS:TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formula:C24H24N4O3Purity:99.4%Color and Shape:SoildMolecular weight:416.47Ref: TM-T77660
1mg39.00€2mg50.00€5mg82.00€10mg120.00€25mg236.00€50mg353.00€100mg517.00€500mg1,099.00€Glofitamab
CAS:Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.
Purity:SDS-PAGE:98.2%;SEC-HPLC:98.0%Color and Shape:LiquidMolecular weight:170.37 kDaOtelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purity:>95%Color and Shape:LiquidPamidronate Disodium
CAS:Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.Formula:C3H9NNa2O7P2Purity:99.86% - 99.93%Color and Shape:White CrystalsMolecular weight:279.03CK-666
CAS:CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.Formula:C18H17FN2OPurity:99.93%Color and Shape:SolidMolecular weight:296.34Ref: TM-T10826
1mg38.00€5mg82.00€10mg133.00€25mg266.00€50mg515.00€100mg715.00€200mg895.00€1mL*10mM (DMSO)90.00€Bisindolylmaleimide VIII acetate
CAS:Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Formula:C26H26N4O4Purity:99.27%Color and Shape:SolidMolecular weight:458.51NMS-P715
CAS:NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formula:C35H39F3N8O3Purity:99.84%Color and Shape:SolidMolecular weight:676.73ML-9
CAS:ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Formula:C15H18Cl2N2O2SPurity:99.69%Color and Shape:Crystalline SolidMolecular weight:361.29ATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formula:C25H39N9O10SPurity:98.27%Color and Shape:SoildMolecular weight:657.7Ref: TM-T10398L
1mg190.00€5mg471.00€10mg663.00€25mg1,036.00€50mg1,429.00€100mg1,830.00€200mg2,498.00€Delcasertib
CAS:Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Formula:C120H199N45O34S2Purity:99.96%Color and Shape:SolidMolecular weight:2880.28Ref: TM-T11740
1mg192.00€5mg485.00€10mg700.00€25mg1,063.00€50mg1,459.00€100mg1,963.00€1mL*10mM (DMSO)1,603.00€Fluocinolone (Acetonide)
CAS:Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Formula:C24H30F2O6Purity:99.29% - 99.82%Color and Shape:Crystals From Acetone & Hexane SolidMolecular weight:452.49Fluorofenidone
CAS:Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.Formula:C12H10FNOPurity:99.85%Color and Shape:SolidMolecular weight:203.21Ref: TM-T15300
2mg34.00€5mg49.00€10mg80.00€25mg147.00€50mg259.00€100mg371.00€200mg523.00€1mL*10mM (DMSO)54.00€Adropin (34-76) (human, mouse, rat)
CAS:Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.Formula:C190H293N55O68S2Purity:94.23% - 99.95%Color and Shape:SolidMolecular weight:4499.82Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formula:C22H28ClN7O3SPurity:99.68% - >99.99%Color and Shape:SolidMolecular weight:506.03Orbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormula:C19H24F3N5O6Purity:97.21% - 98.72%Color and Shape:SolidMolecular weight:475.42Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formula:C16H11N3Purity:99.91%Color and Shape:SolidMolecular weight:245.28Ref: TM-T12359
5mg46.00€10mg58.00€25mg92.00€50mg160.00€100mg236.00€200mg353.00€500mg580.00€1mL*10mM (DMSO)49.00€CMPD101
CAS:CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formula:C24H21F3N6OPurity:99.01% - 99.04%Color and Shape:SolidMolecular weight:466.46Spiperone
CAS:Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.Formula:C23H26FN3O2Purity:99.34% - 99.91%Color and Shape:SolidMolecular weight:395.47Zagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Purity:> 95% - >95.0% (SDS-PAGE)Color and Shape:LiquidMolecular weight:145.3 kDaGNE 2861
CAS:GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.Formula:C22H26N6O2Purity:97.03%Color and Shape:SolidMolecular weight:406.48Ref: TM-T16429
1mg40.00€2mg52.00€5mg82.00€10mg124.00€25mg245.00€50mg409.00€100mg605.00€1mL*10mM (DMSO)87.00€Danicamtiv
CAS:Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Formula:C16H20F3N5O4SPurity:99.38%Color and Shape:SolidMolecular weight:435.42Ref: TM-T15050
1mg129.00€5mg260.00€10mg430.00€25mg710.00€50mg973.00€100mg1,333.00€1mL*10mM (DMSO)286.00€ADH-1 trifluoroacetate
CAS:ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.Formula:C24H35F3N8O8S2Purity:90.08% - 99.98%Color and Shape:SolidMolecular weight:684.71Ref: TM-T1608
2mg42.00€5mg62.00€10mg89.00€25mg167.00€50mg227.00€100mg339.00€200mg482.00€1mL*10mM (DMSO)89.00€CC-99677
CAS:CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.Formula:C22H20ClN5O3SPurity:99.59%Color and Shape:SolidMolecular weight:469.94Verubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8Ref: TM-T13298
5mg52.00€10mg73.00€25mg138.00€50mg200.00€100mg284.00€200mg411.00€1mL*10mM (DMSO)52.00€RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formula:C18H17F3N4O2SPurity:99.09%Color and Shape:SolidMolecular weight:410.41Ref: TM-T12783
1mg120.00€5mg295.00€10mg447.00€25mg707.00€50mg964.00€100mg1,243.00€200mg1,693.00€1mL*10mM (DMSO)326.00€BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formula:C20H20O7Purity:96.57%Color and Shape:SolidMolecular weight:372.37Ref: TM-T14694
1mg79.00€5mg152.00€10mg215.00€25mg351.00€50mg494.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)167.00€Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formula:C22H26ClN7O2SPurity:99.59% - 99.86%Color and Shape:Pale-Yellow SolidMolecular weight:488.01IMAB027
CAS:Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.Purity:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.42 kDaA-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Ref: TM-T14069
1mg34.00€5mg63.00€10mg90.00€25mg161.00€50mg260.00€100mg416.00€500mg888.00€1mL*10mM (DMSO)95.00€Teplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Purity:SDS-PAGE:95.8%;SEC-HPLC:99.7%Color and Shape:LiquidMolecular weight:145.79 kDa(+)-Blebbistatin
CAS:(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.
Formula:C18H16N2O2Purity:99.88%Color and Shape:SolidMolecular weight:292.33ATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurity:98% - 99.98%Color and Shape:SolidMolecular weight:711.67Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurity:99.25%Color and Shape:SolidMolecular weight:537.63Ref: TM-T16130
2mg34.00€5mg54.00€10mg87.00€25mg149.00€50mg255.00€100mg384.00€200mg538.00€1mL*10mM (DMSO)64.00€Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,
Formula:C29H31N7O·CH4SO3Purity:98% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:589.71Cibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purity:SDS-PAGE:99.1%;SEC-HPLC:96.5%Color and Shape:LiquidMolecular weight:191.1 kDaN-Desmethyltamoxifen hydrochloride
CAS:N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formula:C25H28ClNOPurity:99.15%Color and Shape:SolidMolecular weight:393.95AS1949490
CAS:AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.Formula:C20H18ClNO2SPurity:99.94%Color and Shape:SolidMolecular weight:371.88Ref: TM-T14327
1mg38.00€2mg50.00€5mg84.00€10mg119.00€25mg236.00€50mg380.00€100mg555.00€1mL*10mM (DMSO)93.00€Meclofenamic acid sodium
CAS:Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Formula:C14H10Cl2NNaO2Purity:98% - 98.96%Color and Shape:SolidMolecular weight:318.14Tubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formula:C20H14ClNO2SPurity:99.05%Color and Shape:SolidMolecular weight:367.85Larazotide acetate
CAS:Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Formula:C34H59N9O12Purity:95.53% - 99.425%Color and Shape:SolidMolecular weight:785.89PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Purity:95.42%Color and Shape:SoildAbciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaBosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formula:C26H29Cl2N5O3Purity:98.98% - 99.9%Color and Shape:Yellowish-Orange Or Pink To Brownish Solid Solid PowderMolecular weight:530.45NVS-PAK1-1
CAS:NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Formula:C23H25ClF3N5OPurity:99.35%Color and Shape:SolidMolecular weight:479.93
