Building Blocks

[(2-Chlorophenyl)amino]carbonitrile is a model complex that has been studied extensively for its ability to form coordination complexes with anion radicals. The compound was synthesized by reacting cyanamide and the desired chloroaromatic compound in acid conditions. This reaction is a one-step method that can be used to generate many different types of models, which may be reused after they are generated. [(2-Chlorophenyl)amino]carbonitrile has also been shown to react efficiently with molecular orbitals, making it a useful tool for understanding the effect of various functional groups on the stability of metal-containing complexes.

5-Iodo-1-methyluracil is a synthetic pyrimidine nucleoside that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by interacting with the enzyme thymidine kinase, which is required for the conversion of thymine to uracil. 5-Iodo-1-methyluracil also interacts with adenosine deaminase, which converts adenosine to inosine. The activated form of 5-Iodo-1-methyluracil can be transformed into cytotoxic compounds by metathesis reactions, such as those involving carbonyl groups or activated esters. This compound is often used in assays to detect hypervalent iodine compounds.

N-Cycloheptyl-N-ethylamine is a synthetic compound that has been shown to inhibit the tyrosine kinase enzyme. This inhibition prevents the transmission of signals from the receptor to the inside of the cell, which may be responsible for the reduction in inflammation, immunosuppression, and cancer. N-Cycloheptyl-N-ethylamine is being developed as an anti-inflammatory drug for use in autoimmune diseases and cardiovascular diseases. It also has been shown to have anti-cancer properties by inhibiting pyrimidine synthesis in cancer cells.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Azatricyclo[6.3.1.0,4,12]dodeca-1(12),4,6,8,10-pentaene is a synthetic compound that has been shown to have antiviral properties and is being investigated as an agent for the treatment of inflammatory diseases. 2-Azatricyclo[6.3.1.0,4,12]dodeca-1(12),4,6,8,10-pentaene binds to bromodomains in the nucleus and prevents the virus from interacting with it by competitively inhibiting its binding site on the DNA strand. This prevents transcription of genes and therefore inhibits viral replication. The mechanism of action of 2-azatricyclo[6.3.1.0,4,12]dodeca-1(12),4,6,8,10-pentaene has not yet been elucidated

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

(2R,5R)-2,5-Dimethylpyrrolidine HCl ee is a chiral molecule that is the active form of 2,5-dimethypyrrolidine hydrochloride. It is a colorless solid with a melting point of 87 °C. The substance has the chemical formula C4H9NHCl and molecular weight of 206.75 g/mol. It can be classified as an asymmetric compound because it does not have an equal number of atoms on each side of its plane of symmetry. (2R,5R)-2,5-Dimethylpyrrolidine HCl ee has been shown to have antihypertensive properties in rats and rabbits. It also has been used for the treatment of essential tremor and Parkinson's disease. This drug is characterized by being flammable and soluble in ethanol and diethyl ether but insoluble in water. Recrystallized (2R,5R)-

Furan-3-carbohydrazide is a gaseous molecule with an electron configuration of 5s2p3d1. This molecule has a molecular weight of 102.06 and refractivity of 1.5. Furan-3-carbohydrazide has two optical isomers, one with a dipole moment of 1.9 debye and the other with a dipole moment of 3.2 debye, as well as two different electronic structures: five-membered and six-membered. The five-membered electronic structure is more stable than the six-membered electronic structure because it has lower energy levels for the electrons in the orbitals. Furan-3-carbohydrazide is an exothermic molecule that can be synthesized by reacting pyrrole and thiourea in the presence of hydrazine hydrate.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-[(Pyridin-3-ylmethyl)-amino]-ethanol is the methanol analogue of the coordination compound 2-[(pyridin-2-ylmethyl)-amino]-ethanol. The molecule has a chain structure, with two coordination bonds and a total of six atoms. It is a dimeric molecule that can be polymerized to form polymers. The structure is metallic with antiferromagnetic coupling between the two metal centers, which can be assembled into larger structures. This compound interacts with other molecules at the coordinated sites where it binds. Magnetism results from the unpaired electron spins on each metal center and from spin-spin interactions between these centers.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Chlorobenzene-1,3-dicarbaldehyde is a reactive molecule that can be used in organic synthesis. It reacts through an oxidative dimethylamino process to form 2-chloroacetic acid. This molecule is soluble in solvents such as butoxy, chloroform, and acetone. It has substituents at the 2 and 3 positions, which are fluoro and alkylthio groups. The photocyclization of this molecule results in substitution at the 5 position with chloro or trimethylsilyl groups.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold