Alcohols

<p>Stability Hygroscopic<br>Applications 5-(4-aminophenyl)-1,3,4-oxadiazol-2-ol (cas# 113118-47-1) is a useful research chemical.<br></p>

<p>Applications 2-Penten-4-yn-1-Ol is a useful reagent in the silver-​catalyzed cyclization of acetylenic alcohols. It is also employed in the studies related to the field of acetylenic epoxides.<br>References Pale, P., et al.: Eur. J. Org. Chem., 10109 (2000); Malinovskii, M. S., et al.: Tezisy Dokl. - Vses. Konf. Khim. Atsetilena, 5, 82 (1975)<br></p>

<p>Applications (1S)-1-(adamantan-1-yl)ethan-1-ol (cas# 138309-12-3) is a useful research chemical.<br></p>

<p>Applications 4-(1,3-thiazol-4-yl)phenol (cas# 68535-57-9) is a useful research chemical.<br></p>

<p>Applications 4,4-Dimethoxybutan-1-ol is a reactant used in the preparation of tetrahydropyranols and hydropyranooxepans.<br>References Hoffmann, R.W., et. al.: New J. Chem., 25, 102 (2001)<br></p>

<p>Applications 4-Phenoxyphenol is a porous organic material with dumbbell channels that appear throughout its structure. These channels can also host solvent molecules during crystal growth. 4-Phenoxyphenol is also part of a group of phenolic compounds that have potential apoptotic activity, which can be used in the development of new treatments for cancer therapy.<br>References Hansch, C., et al.: Bioorg. Med. Chem., 11, 617 (2003); Thomas, L., et al.: Cryst. Growth. Des., 12, 1746 (2012)<br></p>

<p>Applications M-PEG4-THIOL (cas# 52190-55-3) is a useful research chemical.<br></p>

<p>Stability Acid Sensitive<br>Applications 2-tert-Butyldimethylsilyloxyethanol (cas# 102229-10-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (3S,4R)-4-aminooxolan-3-ol (cas# 153610-14-1) is a useful research chemical.<br></p>

<p>Applications 3,5,5-Trimethyl-1-hexanol can be used as a fragrance material and a flavoring agent for food.<br>References McGinty, D., et al.: Food and Chem. Toxic., 48(Suppl. 4), S47-S50 (2010);Letizia, C. S., et al.: Food and Chem. Toxic., 38(Suppl. 3), S223-S225 (2000)<br></p>

<p>Applications 2-(Ethylamino)ethanol is used in the preparation of novel indole-2-carboxamide and 3-acetamide derivatives as antioxidant protective agents. Also used in the synthesis of novel amino acid based arginase inhibitors used towards the treatments of myocardial ischemia reperfusion injury.<br>References Oelgen, S. et al.: J. Enz. Inhib. Med. Chem., 28, 58 (2013); Van Zandt, M. et al.: J. Med. Chem., 56, 2568 (2013);<br></p>

<p>Applications 2-Ethyl-3-butyn-1-ol is used as an additive in the synthesis of liquid crystal display adhesive.<br>References Ding, A., et al.: Faming Zhuanli Shenqing 5pp. Patent 2015 CODEN:CNXXEV;<br></p>

<p>Applications Mevinolinic Acid, Monoammonium Salt can be used as reactant/reagent in process for the preparation of the Simvastatin precursor, 2,2-dimethylbutanoic acid (1S,3R,7S,8S,8aR)-8-[(3R,5R)-7-(cyclopropylamino)-3,5-dihydroxy-7-oxoheptyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, via an amidation reaction.<br>References Khanna, J., et al.: Indian, IN 184809 A1 20000930 (2000)<br></p>

<p>Applications 1-Butanol is a common chemical reagent used in biodiesel production. Also it has been used in the study the polarization of vapor-deposited 1-butanol films (1) as well as in the preparation of bioavailable CB1 antagonists (2) . Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Gavra, I. et al.: J. Chem. Phys. 2017 Mar 14;146(10):104701.2. Röver, S. et al.: J. Med. Chem. 2013 Dec 27;56(24):9874-96.<br></p>

<p>Applications 2,4,6-Triacetylphloroglucinol (cas# 2161-87-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,10-Decanediol is a substance used in the pharmaceutical study on the composition of essential oils obtained from myrrh and frankincense and their potential anticancer activities. Also used as a reagent in the biological study of modified oligonucleotide with in vivo antitumoral activity.<br>References Chen, Y., et al.: Oncol. Lett., 6, 1140 (2013); Herdewijn, P., et al.: Biomed. Health Res., 24, 182 (1998)<br></p>

<p>References Munafo, A., et al.: J. Pharma. Sci., 77, 169 (1988); Smikalia, M., et al.: Int. J. Pharmaceuticals., 405, 122 (2011); Kakubari, I., et al.: Biol. Pharma. Bull., 29, 1717 (2006);<br></p>

<p>Applications 1-(9H-Purin-6-ylamino)propan-2-ol is a reagent used for organic synthesis and also functions as a plant growth regulator.<br>References Gao, Y., et al.: J. Heterocyclic Chem., 53, 579 (2016); Oda, A., et al.: From Faming Zhuanli Shenqing (2016), CN 105503875 A 20160420; Lira, E. P.: J. Org. Chem., 33, 3355 (1968)<br></p>

<p>Applications 3-Amino-1,2-propandiol is used in the synthesis of Decarbazolyl Carvedilol (D212720), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schaefer, W.H. et al.: Drug. Metab. Dispos., 26, 958 (1998); Neugebauer, G. &amp; Neubert, P.: Eur. J. Drug. Metabol. Ph., 16, 257 (1991); Neugebauer, G. et al.: J. Cardiovasc. Pharm., 10, S85 (1987)<br></p>

<p>Applications Used in the antileishmanial activity of lipidic amino alcohols.<br>References Coimbra, E.: Chem. Biol. Drug Des. 75, 233 (2010).<br></p>

<p>Applications (S)​-​(-​)​-​1-​Phenyl-​1-​propanol is a building block used in the synthesis of inhibitors of steroid 11-β hydroxylation in the adrenal cortex related to androgen production in the fetus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zolle, I. et al.: J. med. Chem., 51, 2244 (2008);<br></p>

<p>Applications 3,5-Dimethoxybenzyl Alcohol is used in the synthesis of Resveratrol (R150000).<br></p>

<p>Applications 4-{[(p-Fluorophenyl)imino]methyl}phenol is used in the preparation of benzylacetones which promote anti-fungal activity.<br>References Sandhar, R. et al.: J. Ind. Council Chem., 22, 32 (2005);<br></p>

<p>Applications pentane-2,3-diol (cas# 42027-23-6) is a useful research chemical.<br></p>

<p>Applications Thietan-3-ol (cas# 10304-16-2) is a useful research chemical.<br></p>

<p>Applications 4-Acetamidobenzyl Alcohol is a useful research chemical, a metabolites of a blocked chloramphenicol producer.<br>References Lewis, E. A., et al.: J. Nat. Prod., 66, 62 (2003)<br></p>

<p>Stability Epimerize in solution<br>Applications 5-Hydroxy-1,3-oxathiolane-2-carboxylic Acid is used in the synthesis of potent antiviral agent (-)-2’-Deoxy-3’-thiacytidine and its enantiomer.<br>References Jin, H.L., et al.: J. Org. Chem., 60, 2621 (1995);<br></p>

<p>Applications 2-[(9Z)-9-Octadecenyloxy]-1,3-propanediol, which is an endogenous cannabinoid receptor ligand.<br>References Suhara, Y. et al.: Chem. Pharm. Bull., 48, 903 (2000);<br></p>

<p>Applications 1,11-Dodecadien-4-ol is an intermediate in the synthesis of 3-Hydroxy Sebacic Acid (H953770), which is a normal urinary 3-hydroxydicarboxylic acid metabolite and can be elevated in patients with peroxisomal disorders such as Zellweger syndrome.<br>References Bernier, F., et al.: Neurology, 59, 1406 (2002), Boekema, E., et al.: J. Biol. Chem., 282, 1 (2007), Goodacre, R., et al.: Metabolomics, 3, 231 (2007),<br></p>

<p>Applications Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.<br>References Ebeling, P., et al.: Lancet, 343, 1479 (1994); Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994); Ramachary, D.B., et al.: RSC Advances, 3, 13497-13506 (2013); Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977);<br></p>

<p>Applications Intermediate in the preparation of Trimebutine metabolites.<br></p>

<p>Applications 3-(Nitroamino)propanol is an analog of 2-(Nitroamino)ethanol (N491750), which is used in the preparation of N-alkylnitratoethyl nitramines as energetic plasticizers for explosives and propellants.<br></p>

<p>Applications (2R)-1-(9H-Purin-6-ylamino)-2-propanol is a reagent for the synthesis of tenofovir disoproxil fumarate, a medication for the treatment of hepatitis B and to prevent and treat HIV/AIDS.<br>References Yan, N., et al.: Jingxi Huagong, 31, 983 (2014); Ripin, D. H. B., et al.: Org. Process Res. Dev., 14, 1194 (2010)<br></p>

<p>Applications 4-Hexadecyloxyphenol is used as a reactant in the enzyme-mediated two-dimensional polymerization of aromatic derivatives on a Langmuir Trough.<br>References Bruno, F., et al.: Ind. Eng. Chem. Res., 34, 4009 (1995)<br></p>

<p>Applications 1,8-Octanediol is used in the synthesis of polymers polyesters and polyurethane.<br>References David, F., et al.: Biomacromolecules, 11, 690 (2010)<br></p>

<p>Applications 3-(methylamino)butan-1-ol (cas# 2704-55-4) is a useful research chemical.<br></p>

<p>Applications 2-(Methylsulfonyl)benzenemethanol is an intermediate used in the synthetic preparation of thiophene inhibitors of polo-like kinase.<br>References Emmitte, K.A., et al.: Bioorg. Med. Chem., 19, 1018 (2009);<br></p>

<p>Applications 2-Thiopheneethanol is a thiophene derivative used in the preparation of oligothiophene isothiocyanates as fluorescent markers for biopolymers. 2-Thiopheneethanol is also used in the preparation of other biologically active compounds such as the analgesic Sulfentanyl and the antithrombotic Clopidogrel Hydrogen Sulfate (C587250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Barbarella, G. et al.: J. Am. Chem. Soc., 123, 11600 (2001); Yang, Z.: Yiy. Gong., 16, 241 (1985); Lin, Z. et al.: Ship. Yu Yao., 12, 235 (2010):<br></p>

<p>Applications Dibenzosuberenol is an intermediate in the synthesis of 5H-Dibenzo[a,d]cycloheptene which itself was used in the synthesis of cyclotribenzylenes. Also functions as a calmodulin inhibitor affecting various crucial cellular processes.<br>References Schmuck, C. et al.: Synth., 5, 655 (2002); Lavoie, P.. et al.: J. Neurobio., 17, 681 (1986);<br></p>

<p>Applications 2-Ethyl-5-hexen-1-ol is used in the synthesis of phthalates as endocrine disrupters.<br>References Nuti, F., et al.: Bioorg. Med. Chem., 13, 3461 (2005); Zlotorzynska, M., et al.: J. Org. Chem., 75, 864 (2010);<br></p>

<p>Applications (2E,4E,6E)-2,4,6-Nonatrien-1-ol is an intermediate in the synthesis of (2E,4E,6E)-2,4,6-Nonatrienal which is an unsaturated aldehyde that is a natural volatile constituent of aggregation pheromones produced by male flea beetles. (2E,4E,6E)-2,4,6-Nonatrienal is also found in licorice root, one of the widely used herbs for its<br>References Zilkowski, B., et al.: J. Agr. Food Chem., 56, 4982 (2008)<br></p>

<p>Applications Ecamsule Triethanolamine is used in the preparation of sunscreens providing a UV filter.<br>References Salvador, A. et al.: Anal. Achim. Acta., 537, 15 (2005);<br></p>

<p>Applications N-Ethyl-N-butan-4-ol-nitrosamine can be used to study lack of tumorigenic effects on rat renal pelvic transitional epithelium of life-​span exposure to low doses of a bladder carcinogen<br>References Shibata, M.A., et.al.: J. Toxicol. Pathol., 6, 47-53, (1993);<br></p>

<p>Applications DL-2-Amino-1-pentanol is a useful intermediate for organic synthesis. It is used in the preparation of amino-substituted pyrimidine derivatives and other aminoethanethiol derivatives with potential antiradiation properties.<br>References Yoo, K. H., et al.: Korean J. Med. Chem., 9, 83 (1999); Fernandez, S., et al.: Synthesis, 9, 713 (1991)<br></p>

<p>Applications 2-O-Hexadecyl Glycerol is an important research chemical where chiral-phase HPLC/MS is used to identify its alkyl group.<br>References Yamashina, T., et al.: Bunseki Kagaku, 55, 643-650 (2006)<br></p>

<p>Applications 3-O-tert-Butyldimethylsilyl-cholest-5-ene-3-ol 24-(2-hydroxyisopropyl) 24-Phenyl Sulfinate is an intermediate in the preparation of Campesterol (C155360).<br></p>

<p>Applications N-Oleoyl Taurine which belongs to the class of N-Acyl Taurines were detected in beta cells of Langerhans islets causing insulin secretion results beta cell dysfunction in type 2 diabetes<br>References Aichler, M., et al.: Cell Metab., 25, 1334-1347 (2017)<br></p>

<p>Applications 2-Biphenylmethanol is a useful reactant in organic synthesis.<br>References Li, Zheng, et al.: Bioorg. &amp; Med. Chem., 25(24), 6647-6652 (2017);Shi, Guangfa, et al.: Org. Let., 18(12), 2958-2961 (2016)<br></p>

<p>Applications (E)-5-(3,5-Bis(benzyloxy)phenyl)pent-4-en-2-ol is an intermediate used in the synthesis of 4''-Hydroxycannabidiol (H824830), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 4''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>

<p>Applications 4-PROPOXYPHENOL (cas# 18979-50-5) is a useful research chemical.<br></p>

<p>Applications Used for production of peptide thioester.<br>References Gaeta, A., et al.: Bioorg. Med. Chem. Lett., 20, 4649 (2010),<br></p>

<p>Applications (1S)-1-(4-phenylphenyl)ethan-1-ol (cas# 150283-02-6) is a useful research chemical.<br></p>

<p>Applications 1,2,5-Pentanetriol is used as a modifier in the preparation of polyoxymethylene having excellent impact resistance.<br>References Byun, Gyung S., et al.: PCT Int. Appl., WO 2018074781 A1 20180426 (2018)<br></p>

<p>Applications Bis(4-diethylaminophenyl)methanol (cas# 134-91-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1,7-Heptanediol is used in the treatment of cardiovascular disease. Also used in the synthesis of nonpeptidic inhibitors of human lung tryptase.<br>References Pepys, M. et al.: Nature. 440, 1217 (2006); Burgess, L. et al.: PNAC, 96, 8348 (1999);<br></p>

<p>Applications S-(+)-2-Amino-1-propanol is an aliphatic amino alcohol shown to induce an antiproliferative effect in B16 melanoma cells. S-(+)-2-Amino-1-propanol is used in the preparation of oxazolines which are often used as ligands in homogeneous catalysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Landau, O. et al.: Cancer Lett., 69, 203 (1993); Gant, T.G. et al.: Tetrahedron, 50, 2297 (1994);<br></p>

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications cis-4-Decen-1-ol is a reactant in the synthesis of epoxyisoprostanes as antiinflammatory agents.<br>References Egger, J., et. al.: Angew. Chem. Int. Edit., 52, 5382 (2013)<br></p>

<p>Stability Air Sensitive<br>Applications Thiol-PEG2-acid (cas# 1379649-73-6) is a useful research chemical.<br></p>

<p>Applications 1-(hydroxymethyl)cyclopentan-1-ol (cas# 74397-18-5) is a useful research chemical.<br></p>

<p>Applications 4-Pentyn-1-ol is an alkyne alcohol that is used as an initiator in ring-opening polymerization reactions. 4-Pentyn-1-ol is capable of undergoing cyclosisomerization, and is also used as a reactant in the synthesis of (+)-Serinolamide A, a cannabinoid CB1 receptor agonist.<br>References Gao, Y., et al.: Tetrahedron Lett., 54, 6511 (2013); Liao, R., et al.: Proc. Nat. Acad. Sci., 107, 22523 (2010); Miranda, P., et al.: Org. Lett., 5, 1979 (2003); Xu, N., et al.: Macromol. Chem. Phys., 208, 730 (2007)<br></p>