Amines

<p>2-Amino-3-fluorobenzoic acid is a covid-19 pandemic anti-infective agent that has been shown to modulate the nicotinic acetylcholine receptor. It has been shown to be effective in preventing the spread of influenza A (H1N1) and other flu strains, as well as the related H5N1 avian flu. 2-Amino-3-fluorobenzoic acid is an organofluorine compound with a five membered ring and fluorine atom in the para position. 2-Amino-3-fluorobenzoic acid binds to the ligand binding site of the acetylcholine receptor, which is found on nerve cells. The drug competitively inhibits acetylcholine's binding to this site, preventing activation of the receptor and blocking transmission of nerve impulses across synapses. This prevents muscle contraction, leading to paralysis and death from respiratory</p>

<p>3'-Aminopropionanilide is a synthetic chemical that belongs to the group of aminopropionates. It has been used as a reaction component and reagent in organic synthesis. 3'-Aminopropionanilide is a versatile building block, which can be used to synthesize complex compounds with different functions. This compound is also an intermediate in the synthesis of other chemicals, such as pharmaceuticals or agrochemicals. 3'-Aminopropionanilide has a CAS number of 22987-10-6.</p>

<p>Precusor for preparation of indinavir; a chiral ligand for asymmetric synthesis</p>

<p>Cbz-L-glutamine is a water soluble compound that is used in the synthesis of pomalidomide. It is synthesized through a stepwise amide formation from methylamine and ethylene diamine. Cbz-L-glutamine has been shown to have an inhibitory effect on cancer cells, which may be due to its ability to break down hydroxamic acids. This chemical reaction causes the release of hydrogen ions, which leads to the disruption of various cellular processes, such as DNA replication and protein synthesis. The uptake of Cbz-L-glutamine by cancer cells has been shown in tissue culture experiments.</p>

<p>5-Carboxymethoxytryptamine hydrochloride (5CMT) is a chemical compound that belongs to the group of useful building blocks. It is a versatile intermediate that can be used in the synthesis of many important compounds. 5CMT reacts with amines and alcohols to form amides and esters. It also reacts with carboxylic acids to form acid halides and anhydrides. 5CMT has been shown to be a useful scaffold in organic synthesis, as it can be converted into various derivatives. 5CMT is soluble in water, methanol, ethanol, acetone, and dichloromethane.</p>

<p>5,6-Diamino-1,3-dipropyluracil (DAU) is a synthetic drug that acts as an adenosine receptor antagonist. DAU binds to the adenosine receptors in the brain and inhibits the binding of adenosine, which may result in an anti-congestive effect. DAU has been found to be a potent inhibitor of the A2A adenosine receptor at nanomolar concentrations. This inhibition may be due to its ability to form covalent bonds with the receptor or its affinity for or blocking of agonist binding sites on the receptor. It also has been shown to have affinity for dopamine receptors, although it is not yet known if this activity contributes to its anti-congestive effects.</p>

<p>2,6-Diaminopurine hemisulfate salt is a fine chemical that can be used as a building block for research chemicals, reagents, and specialty chemicals. It has been shown to be useful in the synthesis of various types of complex compounds. 2,6-Diaminopurine hemisulfate salt is also versatile in the sense that it can be used as an intermediate in reactions or as a scaffold for chemical synthesis. This product has CAS number 69369-16-0.</p>

<p>3-Amino-4-chlorobenzoic acid is a diacid that has been shown to have strong steric interactions with manumycin and fibrinogen, which are proteins found in the human body. 3-Amino-4-chlorobenzoic acid has a carboxylate group at one end of the molecule, which can coordinate to metal ions such as chloride. The other end of the molecule contains a hydrogen atom that can form hydrogen bonds with other molecules. 3-Amino-4-chlorobenzoic acid can be synthesized by reacting 2 moles of chloroacetyl chloride with an amino acid.</p>

<p>3-Hydroxy-4-methoxyphenethylamine HCl is an amine that is found in plants. It has been shown to be a reactive compound with a carbonyl group and an amine group. 3-Hydroxy-4-methoxyphenethylamine HCl can act as a dopamine receptor agonist, causing the release of serotonin from neurons. This chemical also has anti-inflammatory properties and may be used to treat inflammatory diseases such as asthma. 3-Hydroxy-4-methoxyphenethylamine HCl may also have blood pressure lowering effects.</p>

<p>N-tert-Butoxycarbonyl tyramine is a molecule that has been shown to have anti-tuberculosis properties. It is synthesized by reacting N-Boc-tyrosine with chloroform in the presence of an acid catalyst. The reaction product is a zwitterion, which can be converted to an ionic form by treatment with mineral acids or phosphoric acid. The chloride ion is released from the molecule and reacts with phosphate ions to form hydroxyapatite, which is used as a bone substitute. This compound also has potential for use in cancer treatments due to its ability to inhibit cell proliferation and induce apoptosis in cancer cells.<br>The uptake of this drug was studied using caco-2 cells cultured on plastic membrane inserts in contact with phosphate buffered saline (PBS). The results showed that it had a high uptake rate and concentration in these cells. This compound was also found to have an inhibitory effect on phosphatase</p>

<p>[2-(1,3-Benzodioxol-5-yloxy)ethyl]amine hydrochloride is a versatile building block for organic synthesis. It can be used as a starting material for the synthesis of many complex compounds and research chemicals. This compound has been shown to have high quality, useful scaffolds, and is an excellent reagent in many chemical reactions.</p>

<p>Alkylated diphenylamines are reactive compounds that have been used as antioxidants in industrial processes. These antioxidants inhibit the propagation of oxidation reactions, which can lead to the degradation of polycarboxylic acids. Alkylated diphenylamines are usually synthesized from phenyl groups and fatty acid esters. They are also known as synthetic antioxidants and are used in a variety of industries, such as food production and textiles. Alkylated diphenylamines have been shown to react with metal hydroxides, such as magnesium oxide or sodium nitrate, to form reaction products that include alkanes and alkenes. The viscosity of these compounds is dependent on the length of their fatty acid chains; the longer the chain length, the lower the viscosity.</p>

<p>Initiates acrylamide polymerization in combination with ammonium persulfate</p>

<p>Please enquire for more information about methyl 2-nitrilo-3-methylthio-3-(phenylamino)prop-2-enoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-[(1-Methyl-1H-indol-3-yl)methyl]cyclohexanamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Use as a positive control when detecting nitroreductase activity</p>

<p>Please enquire for more information about 2-amino-4-(3,4-dimethoxyphenyl)-5-oxo-4,6,7,8-tetrahydro2H-chromene-3-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-tert-Butyl-N-(2-methyl-1-phenylpropyl)-O-(1-phenylethyl)hydroxylamine is a telechelic metathesis polymer that is soluble in organic solvents. This product has been shown to copolymerize with styrene, which can be used as a monomer. Copolymers of this product are resistant to chemical reactions and metal ion. The reaction time and temperature for this product depends on the nature of the monomers and initiator used. This substance is also able to undergo metathesis reactions, such as those involving silicon.</p>

<p>Please enquire for more information about 4-(2,5-Dimethoxyphenyl)-1,3-thiazol-2-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride is the salt form of a chemical compound that belongs to the group of acetylation agents. This chemical is highly soluble in water and is used as a reagent to acetylate amines. The industrial process for this compound begins with an acetone solution of 2,3-dihydroindene. Acetyl chloride reacts with 2,3-dithiobenzoyl chloride in an acid environment to produce 5,6-diethyl-2,3-dihydroindane. The product is treated with hydrogen chloride gas to produce 5,6-diethyl-2,3 dihydroindanamine hydrochloride. This compound has been shown to be toxic for aquatic life and can cause environmental pollution when released into the environment.</p>

<p>4-(Dimethylaminobenzylidene)rhodanine is a monosodium salt of the drug rhodanine. Rhodanine is a small-molecule, kinetically stable, and surface active agent that inhibits tumor growth by binding to sulfamoyl chloride, inhibiting the synthesis of DNA. Rhodanine has been shown to inhibit the growth of colon cancer cells in mice and human leukemia cells in vitro. This drug also inhibits the proliferation of erythrocytes and platelets. Rhodanine binds to chloride ions on cell surfaces and forms a complex with silver ions that can then be detected by electron microscopy or profiling studies using hydroxide solutions. The efficacy of 4-(dimethylaminobenzylidene)rhodanine as an anticancer agent is dependent on its concentration. A blood sample containing 4% dimethylaminobenzylidene rhodanine was found to have anti-t</p>

<p>2-Benzyltryptamine (2BT) is a synthetic substance that has been used as a research chemical in the study of the interactions between serotonergic and dopaminergic neurotransmission. In one study, 2BT was found to inhibit dopamine uptake in rat brain synaptosomes and to bind to both serotonin and dopamine receptors. 2BT has also been shown to have an affinity for melatonin receptors, which may be due to its structural similarity to melatonin.</p>

<p>5-Aminogramine is a fine chemical that is used as a versatile building block for the synthesis of complex compounds. 5-Aminoguanidine is an aminoguanidine compound that has been reported to be useful in the synthesis of reagents and speciality chemicals, such as heterocycles, polymers, and pharmaceuticals. 5-Aminoguanidine has been used as a reactant in the preparation of high quality products with various applications. It is also known to be a useful intermediate for reactions involving nucleophiles or electrophiles. Furthermore, it can be used as a scaffold for the synthesis of other compounds.</p>

<p>5-Amino-2-fluorobenzoic acid (5AFBA) is a synthetic aniline that is used as a fluoroquinolone antibiotic. 5AFBA inhibits the synthesis of trehalose, which is vital for bacterial growth. This drug also has been shown to be active against Mycobacterium tuberculosis and Mycobacterium avium complex. 5AFBA has also been shown to have antifungal properties, inhibiting the synthesis of ergosterol in the fungal cell membrane. 5AFBA can be modified by alkylation with geranyl groups or N-methylation at the amino group. These modifications have been shown to increase its antibacterial activity against Pseudomonas aeruginosa.</p>

<p>Methyl 4-aminobutyrate HCl is an ester hydrochloride that is used as a chiral auxiliary in the synthesis of aminobutyric acid. It has been shown to have cognitive enhancing effects and to increase brain levels of l-glutamic acid. Methyl 4-aminobutyrate HCl also inhibits the uptake of chloride ions into synaptic vesicles, which may be due to its ability to bind with plasma proteins. This drug has been shown to have pharmacological effects on rats when administered at a dose of 1mg/kg.</p>

<p>Please enquire for more information about 4,6-Diamino-2-nitro-m-xylene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Aminobenzamide is a drug that has been shown to be effective in the treatment of temozolomide-induced neuronal death. 3-Aminobenzamide inhibits the synthesis of ATP and blocks its binding to the atp-binding cassette transporter, which prevents the transport of this nucleotide into cells. This results in cell death due to insufficient energy metabolism and inability to repair DNA damage. 3-Aminobenzamide also increases production of reactive oxygen species, which are involved in reperfusion injury and myocardial infarcts. 3-Aminobenzamide is used as a model system for studying DNA repair and energy metabolism.</p>

<p>Please enquire for more information about Ethyl 2-(4-((5-chloro-2-methoxyphenyl)amino)-3,5-thiazolyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-N-Methylaminoethyl chloride·HCl is a nitro compound that has been programmed to inhibit PD-1. It is an inhibitor of this protein, which is involved in the regulation of immune responses. Inhibition of PD-1 can lead to an increase in T cell function and proliferation, as well as the production of cytokines. 2-N-Methylaminoethyl chloride·HCl has been shown to be a potent inhibitor of PD-1 with a Ki value of 2 nM, and it inhibits PD-L1 at concentrations up to 10 μM. This drug also inhibits resorcinol at low concentrations (0.5 μM). It is a synthetic molecule that was generated for screening purposes and does not have any other known biological activity.</p>

<p>2-Amino-3-methoxybenzoic acid hydrochloride is a synthetic monosubstituted hydroxy analog of the natural alkaloids, which are substituted with an amino group. It is produced by the demethylation of 2-amino-3-hydroxypyridine and reacts with caprolactam to form 2,6-dihydroxybenzaldehyde. It has been used in the synthesis of methoxyanthranilic acid, which is a synthetic analogue of anthranilic acid. Hydrochloric acid can be added to 2-amino-3-methoxybenzoic acid hydrochloride to produce 2,6-dihydroxybenzoyl chloride. This compound also undergoes condensation reactions with methoxyanthranilic acid to form 2,6-dimethoxybenzaldehyde.</p>

<p>N-Ethylmethylamine is a compound that is used in the preparation of fatty acid methyl esters, which are used as biomarkers for assessing lipid metabolism. It has also been shown to be an effective antimicrobial agent against bacteria, such as Pseudomonas aeruginosa and Escherichia coli. N-Ethylmethylamine interacts with membranes by binding to phospholipids and amines. The mechanism of this interaction is not fully understood, but it may be due to steric interactions or hydrogen bonding. N-Ethylmethylamine reacts with chlorine atoms in solution to form chloramines, which are more stable than free chlorine molecules. This reaction can be catalyzed by ph optimum or activated carbon. The reaction between hydrochloric acid and methyl ethyl amine produces methylamine gas, which is toxic in high concentrations.</p>

<p>Applications (αS)-α-Amino-4-nitrobenzenepropanamide (cas# 81677-61-4) is a compound useful in organic synthesis.<br></p>

<p>Applications (S)-2-(Benzylamino)propan-1-ol is a useful research chemical for the preparation of cross-benzoin products of heteroaromatic aldehydes and amino aldehydes.<br>References Haghshenas, P., et al.: J. Org. Chem., 81, 12075-83 (2016);<br></p>

<p>Applications Diaminomaleonitrile is a reagent used for the synthesis of 1,4-diazepine-2,3-dicarbonitrile dervatives. Also, it is used for the synthesis of Diaminomaleonitrile-based Schiff bases with a donor-acceptor structure and an aggregation-enhanced emission feature.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wieczorek, E., et al.: Tetrahedron Lett., 58, 758-761 (2017); Han, T., et al.: J. Mater. Chem. C Mater. Opt. Electron Devices, 4, 10430-10434 (2016);<br></p>

<p>Applications (S)-Tert-butyl 2-((tert-butoxycarbonyl)amino)-6-hydroxyhexanoate which is a biochemical marker of bone turnover for management of metabolic bone diseases.<br>References Turner, W., et al.: Biol. Psychiatry, 14, 177 (1979), Miyata, T., et al.: Kidney Int., 60, 2351 (2001), Politi, P., et al.: Neurosci. Lett., 396, 163 (2006),<br></p>

<p>Applications 4-Aminomorpholine (cas# 4319-49-7) is a useful research chemical.<br></p>

<p>Applications 5-Amino-2-chlorobenzoic Acid is a reagent in the preparation of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL.<br>References Sleebs, B.E., et al.: J. Med. Chem., 56, 5514, (2013)<br></p>

<p>Applications Sulfur Trioxide Trimethylamine Complex is a reagent that is used for the design and synthesis of Rho kinase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Takami, A., et al.: Bioorg. Med. Chem., 12, 6317 (2004);<br></p>

<p>Applications (2R,3R)-2,3-Bis(acetyloxy)butanedioic Acid Mono[(10S)-5-(aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl] Ester is an intermediate in the synthesis of Eslicarbazepine (M546510), a novel central nervous system drug.<br>References Duncan, J., et al.: Br. J. Clin. Pharmacol., 53, 123 (2002), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Coppola, G., et al.: CNS Drugs, 18, 133 (2004),<br></p>

<p>Applications Used as a reactant or reagent in preparation of N-alkyl carbamates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lazewska, D. et al.: BioMed. Chem. Let., 19, 6682 (2009);<br></p>

<p>Applications Diethylamine, can be used for the preparation of alkali metal diethylamides, generated with n-BuLi or NaH, have been used for the cleavage of ethers. Also, in combination with Lithium aluminum hydride, generates lithium tris(diethylamino)aluminum hydride, which is a useful selective reducing agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cha, J.S., et al.: J. Org. Chem., 52, 5030 (1987); Tetrahedron Lett., 32, 6903 (1991);<br></p>

<p>Applications N-tert-Butoxycarbonyl-3,4-dibenzyloxyphenylethylamine is an intermediate used in the synthesis of S-(-)-Tretoquinol Hydrochloride (T798100), which belongs to the class of adrenergic inhalants, selective β-2-adrenoreceptor agonists. S-(-)-Tretoquinol is used in the treatment of obstructive airway diseases. S-(-)-Tretoquinol is a bronchodilator.<br>References Meshi, et al.: Biochem. Pharmacol., 19, 2937 (1970), Satoh, et al.: Chem. Pharm. Bull., 19, 667 (1971),<br></p>

<p>Applications AMMONIUM IODIDE (cas# 12027-06-4) is a useful research chemical.<br></p>

<p>Stability Volatile<br>Applications Isopropylamine is an organic compound is a widely used for the synthesis of pharmaceutical and agricultural goods such as glyphosphate herbicides and as an additive for petroleum industry.<br> E0<br>References Dam, J.H. et al.: Chem. A. Eur. J., 16, 6820 (2010); Latli, B. et al.: J Labelled. Compd. Radiopharm., 48, 447 (2005); Guadry, D., et al.: Biomed. Mass. Spectro., 12, 269 (1985);<br></p>

<p>Applications Ammonium sulfide is a very useful reagent in various aspects ranging from large scale production of textile manufacture, trace metal analysis, patina to bronze, and as well as cell culture and organic reactions/synthesis. Recently it has been used as a cleaning solution in the study of semiconductor growth on indium phosphide with various metals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ferrandis, P., et al.: J. Appl. Phys., 123, 161534/1-161534/10 (2018)<br></p>

<p>Applications Triethylmethylammonium Chloride (cas# 10052-47-8) is a useful research chemical.<br></p>

<p>Applications 3-Dimethylamino-1-propyne is used as a reactant in the synthesis of quinazoline derivatives such as (2Z)-Afatinib (A355305) which may be used in the treatment of some cancers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsou, H., et. al.: J. Med. Chem., 44, 2719 (2001)<br></p>

<p>Applications 2-(Dimethylaminomethylene)cyclohexanone is an intermediate in the synthesis of 2-Pentylidenecyclohexanone (P280255), a fragrance chemical. It can also be used in the synthesis of dialkylphenols in the presence of zirconium catalyst.<br>References Tetsuo, B. et al.: Kenkyu Hokoku - Asahi Garasu Zaidan, 58, 201 (1991); Hostynek, J. J., et al.: Toxicology in Vitro, 11, 377 (1997);<br></p>

<p>Applications N-(β-Cyanoethyl)-N-(ethoxycarbonylethyl)benzylamine is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-(Dimethylamino)-1,2-propanediol is a reagent in the synthesis of 1,2-Dioleoyl-3-trimethylammonium-propane, Chloride (D484450).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Ammonium Molybdate can be used to improve efficiency of pig purine as a fertilizer<br>References Atares Real, S., et.al.: PCT Int. Appl. WO 2020225459 A1, 30, (2020);<br></p>

<p>Applications Tetrahydro-2-furanmethanamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors<br>References Lopez-Rodriguez, M. et al.: 44, 4504 (2001); Liu, G. et al.: J. Med. Chem., 50, 3086 (2007);<br></p>

<p>Applications 4-Amino-1-(diethylamino)pentane was used as a reagent in the synthesis of chromone-2-carboxamide derivatives which displayed cytotoxic activity against specific cancer cell lines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bousejra-ElGarah, F., et al.: Med. Chem. Res., 1054, pages ahead of print (2016);<br></p>

<p>Applications Tetrabutylammonium Borohydride is a strong reducing agent used in the synthesis of hyperbranched polyglycerol grafting on the surface of silica-coated nanoparticles.<br>References Panja, P. et al.: ACS Sust. Chem. Eng., 5, 4879 (2017);<br></p>

<p>Applications N,N-Diethyl(trimethylsilyl)amine is a chemical reagent with wide application in organic chemistry. Used in stereospecific addition reactions as well as in SN2 nucleophilic substitutions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bassindale, A. et al.: J. Organometal. Chem., 667, 66 (2003); Hagiwara, H. et al.: J. Chem. Soc., Perk Trans., 3, 316 (2002);<br></p>

<p>Applications Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans (1), and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Akesson B. et al.: Int Arch Occup Environ Health. 1986;57(4):297-302. 2. Roos RW. et al.: J Chromatogr. 1986 Dec 24;370(3):403-18.<br></p>

<p>Applications 2-(4-Phenoxyphenoxy)ethanamine is an intermediate in the synthesis of Fenoxycarb-d3 (F248871), a labelled form of Fenoxycarb (F248870). Fenoxycarb is a carbamate insect growth regulator by preventing immature insects from reaching maturity by mimicking juvenile hormone. Used as a standard for Pesticide detection. Fenoxycarb is also used in cannabis testing kits as a component of pesticide mixes (P698235).<br>References El-Saeid, M.H., et al.: J. Chem., 10, (2013); Coors, A., et al.: Environ. Toxicol. Chem., 31, 1239 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications 3-Phenylpropylamine is an compound used for the synthesis of various pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kamochi, Y., et al.: Tetrahedron. Lett., 32, 3511 (1991);<br></p>

<p>Applications Protected ε-Aminocaproic Acid (A603015). Used in the preparatiom of esters of 6-aminohexanoic acid as antibacterial agents. EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carboxy peptidase, plasmin, and plasminogen activator.<br>References Dolezal, P., et al.: Pharm. Res., 10, 1015 (1993), Vavrova, K., et al.: Curr. Med. Chem., 12, 2273 (2005), Holas, T., et al.: Bioorg. Med. Chem., 14, 7671 (2006),<br></p>

<p>Applications (3-(((2-Hydroxyethyl)(methyl)amino)methyl)phenyl)(phenyl)methanone-d3 is an intermediate in the synthesis of Nefopam-d3 (N389402), a cyclized labelled analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants.<br>References Bassett, et al.: Br. J. Pharmacol., 37, 69 (1969), Klohs, et al.: Arzneim.-Forsch., 22, 132 (1972), Hell, et al.: Drugs, 19, 249 (1980),<br></p>

<p>Applications N,N’-Di-Boc (R)-1-Azido-3-[[3-fluoro-4-(morpholin-4-yl)phenyl]amino]propan-2-yl Acetate is an intermediate used in the synthesis of N-Desacetyl-N,O-descarbonyl O-Acetyl Linezolid (D288280), which is an impurity of Linezolid (L466500); an oxazolidinone antimicrobial that inhibits bacterial mRNA translation.<br>References Brickner, S.J., et al.: J. Med. Chem., 39, 673 (1996); Ford, C.W., et al.: Antimicrob. Agents Chemother., 40, 1508 (1996); Rybak, M.J., et al.: Pharmacotherapy, 18, 456 (1998); Stevens, D.L., et al.: Clin. Infect. Dis., 34, 1481 (2002)<br></p>

<p>Applications 3-Morpholinopropylamine is a reactant used in the preparation of pyridinyl-quinazolinone derivatives as potential anti-influenza A virus compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, S., et. al.: Chem. Biol. Drug Design., (Ahead of Print) (2015)<br></p>

<p>Applications N-Isopropylcyclohexylamine is a reagent that is used in the synthesis of N3-substituted coformycin aglycon analogs that inhibit AMP deaminase or adenosine deaminase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bookser, B.C., et al.: J. Med. Chem., 43, 1495 (2000);<br></p>

<p>Applications N-(2-N’,N’-Dimethylaminoethyl)maleamic Acid (cas# 116503-79-8) is a compound useful in organic synthesis.<br></p>

<p>Applications (Z)-5-(2,3-Bis(tert-butoxycarbonyl)guanidino)-2-((tert-butoxycarbonyl)amino)pentanoic Acid is an intermediate used in the synthesis of N-​(4-​Amino-​5-​oxoheptyl)​guanidine Trifluoroacetate Salt (A633006), which is a biosynthetic intermediate in the study of saxitoxin gene cluster in cyanobacteria.<br>References Kellmann, R., et al.: Appl. Environ. Microbiol., 74, 4044 (2008)<br></p>

<p>Applications 4,5-Dimethyl-o-phenylenediamine is used in biological processes as a substrate for CobT nicotinate-mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella typhimurium LT2.<br>References Trzebiatowski, J.R., et al.: J. Biol. Chem., 272, 17662 (1997); Johnson, M.G., et al., J. Biol. Chem., 267, 13302 (1992); Cheong, C., et al.: J. Biol. Chem., 277, 41120 (2002)<br></p>

<p>Applications N-ethyl-3-phenyl-1-propanamine hydrochloride (cas# 13125-63-8) is a useful research chemical.<br></p>

<p>Applications N-Aminohexamethylenimine is a sesquiterpene lactones with anti-hepatitis C virus activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rossini, M., et al.: Lett. Drug. Des. Discov., 9, 881 (2012); Hines, R.N., et al.: J. Pharmacol. Exp. Therap., 214, 88 (1980);<br></p>

<p>Applications Tetraethylammonium Tetrafluoroborate is used in the preparation of some organic salts of fluoboric acids.<br>References Wilke-D., et al.: Ber. Dtsch Chem. Ges.; 60B, 115 (1927)<br></p>

<p>Applications 9-(2-Carboxyphenyl)-2,7-dimethyl-3,6-bis(ethylamino)xanthylium is an intermediate in the synthesis of SkQR1 (S555050), a mitochondria-targeted plastoquinone antioxidant that exhibits neuroprotective effect. Potent Mitochondrial Targeted antioxidant protecting against the anti-cancer treatment related to oxidative stress (1). Depicted positive effects on rat memory. (2)SkQRl is the substrate of multidrug resistance pump P-glycoproten (Pgp 170) and selectively protects Pgp 170-negative cells against oxidative stress (3)<br>References Fetisova EK, et al. 2010. FEBS Lett. Feb 5;584(3):562-6Stelmashook EV, 2015. Biochemistry (Mosc). May;80(5):592-5 Fetisova EK, et al. 2015. Radiat Res. Jan;183(1):64-71<br></p>

<p>Applications Cumylamine is a reactant in the preparation of anti-malarial drugs. Also used in the preparation of HCV inhibitors.<br>References Ciana, C. et al.: Bioorg. Med. Chem. Lett., 23, 658 (2013); Girijavallabhan, V. et al.: Bioorg. Med. Chem. Lett., 22, 5652 (2012);<br></p>

<p>Applications 3-(Diethylamino)-2,2-dimethylpropanol is a reactant used in the preparation of herbicides, several local anesthetics and histamine H3 receptor antagonists.<br></p>

<p>Applications 2,3-Diaminophenol<br></p>

<p>Applications (S)-3-(Allyl(methyl)amino)-1-(thiophen-2-yl)propan-1-ol is an intermediate in the syntehsis of 4-Hydroxy Duloxetine β-D-Glucuronide Sodium Salt (H941805), which is a metabolite of Duloxetine.<br>References Lantz, R.J., et al.: Drug Dispos. Metab., 31, 1142 (2003); Detke, M., et al.: J. Clin Psy., 63, 308 (2002); Bymaster, F.P., et al.: Bioorg. Med., Chem. Lett., 13, 4477 (2003);<br></p>

<p>Applications rac (Aminomethyl)ethylenediaminetetraacetic Acid tetra-(t-Butyl Ester) (cas# 1391052-55-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Diisobutylamine is a reagent used in organic synthesis including the preparation of bx7 inhibitors which may be useful in the treatment of certain cancers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simhadri, C. et al.:ACS Omega, 1, 541 (2016);<br></p>

<p>Applications 2-Amino-4,5,7,8-tetrahydro-6-(N-carbethoxy)thiazolo[5,4-d]azepine (cas# 887352-57-0) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Ethylethylenediamine<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-(4-Aminophenyl)propionic acid (cas# 2393-17-1) is a useful research chemical.<br></p>

<p>Applications N-Ethylbenzylamine is a reactant or reagent used in various organic syntheses. It is used in the preparation of CXCR4 injhibitors which are used to treat cancer metastasis and inflammation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bai, R. et al.: Eur. J. Med. Chem., 118, 340 (2016);<br></p>

<p>Applications Intermediate in the preparation of Mentane.<br>References Shutske, G., et al.: Bioorg. Med. Chem. Lett., 2, 865 (1992),<br></p>

<p>Applications 4-(Diethylamino)butylamine has been used on prostatic cancer cells and has been found to reduce the putrescine uptake inhibitory activity.<br>References Heston, W.D.W., et. al.: Biochem. Pharmacol., 36, 1849 (1987)<br></p>

<p>Applications 2-Aminobenzyl alcohol (cas# 5344-90-1) is a useful research chemical.<br></p>

<p>Applications trans-(1R,2R)-N,N’-Bismethyl-1,2-cyclohexanediamine is a useful research chemical for organic synthesis and other chemical processes.<br>References Bollenbach, M., et al.: Chem. Eur. J., 23, 13676 (2017); Thaisrivongs, D. A., et al.: Org. Lett., 18, 5780 (2016)<br></p>

<p>Applications 5-Amino-2-chloro-4-fluorobenzoic Acid is an intermediate in the synthesis of Saflufenacil-d7 (S081802). Saflufenacil-d7 is the labeled version of Saflufenacil (S081800), which is a herbicide of the pyrimidinedione chemical class used for the preplant burndown and selective preemergence dicot weed control in different field crops. It was found to inhibit protoporphyrinogen IX oxidase (PPO) enzyme.<br>References Knezevic, S., et al.: Crop Prot., 29, 148 (2010); Grossmann, K., et al.: Weed Sci., 58, 1 (2010)<br></p>

<p>Applications 10-Amino-1-decanol (cas# 23160-46-5) is a compound useful in organic synthesis.<br>References Lee, T., et al.: J. Biol. Chem., 270, 5375 (1995),<br></p>

<p>Applications (2S)-2-[[(phenylmethoxy)carbonyl]amino]-4-Pentenoic acid is a useful building block, and has been used in the regioselective preparation of nonracemic silylated amino acids.<br>References Marchand, D.; et al.: Eur. J. Org. Chem., 18, 3107 (2008).<br></p>