Amines

<p>1,5-Diaminoanthraquinone (1,5-DA) is an intermolecular hydrogen bonding compound that has been used as an optical sensor. The 1,5-DA molecule has the ability to form hydrogen bonds with chloride and sodium carbonate. This interaction can be exploited for surface-enhanced Raman spectroscopy of cell nuclei. The 1,5-DA molecule also interacts with supramolecular assemblies to produce surface-enhanced Raman scattering. In addition, 1,5-DA has a metal chelate property that allows it to bind to ferrocene carboxylic acid molecules. It can also form hydrogen bonds with vinyl alcohol molecules in multiwall carbon nanotubes. The molecular structure of 1,5-DA consists of rings containing five carbons each. These rings are linked together by amine groups and are attached to a central nitrogen atom on one end and a hydroxyl group on the other end.</p>

<p>Vasopressin 3-mercaptopropionyl-Tyr-Phe-Val-Asn-Cys-Pro-D-Arg-Gly-NH2 is a peptide hormone that is involved in the regulation of water balance and blood pressure. It is a vasoconstrictor and has been shown to have an inhibitory effect on cellular targets such as soluble guanylate cyclase, which are involved in the synthesis of cGMP. Vasopressin 3-mercaptopropionyl-Tyr-Phe-Val-Asn-Cys Pro D Arg Gly NH2 also binds to the oxytocin receptor, which may be responsible for its vasodilatory effect.</p>

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<p>2-Amino-3,5-dibromobenzonitrile is an electrophile that is used to synthesize various boronic acid derivatives. It also inhibits butyrylcholinesterase and 2-aminobenzonitrile, enhancing the activity of organophosphorus cholinesterase inhibitors. 2-Amino-3,5-dibromobenzonitrile has been shown to react with nucleophiles at the alpha position to form a stable intermediate. This reaction has been shown to be reversible in aqueous solution. The compound has been evaluated as a potential chemotherapeutic agent against cancer cells in vitro.</p>

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<p>2-Amino-5,6-dihydro-4H-benzothiazol-7-one is a thiourea that is used as a reactant in the synthesis of brominated compounds. It reacts with ethanol to form 2,5,6-triaminopyrimidine and hydrogen bromide. This reaction occurs in the presence of acid such as hydrochloric acid or acetic acid. The reflux reaction is commonly conducted at elevated temperatures and pressures.</p>

<p>2-[4-(Diethylamino)-2-hydroxybenzoyl]benzoic acid hexyl ester is a sunscreen agent that has been shown to be effective against the formation of skin cancer. This compound is a white powder that can be used as a cream or lotion and is typically applied to the skin before going out in the sun. 2-[4-(Diethylamino)-2-hydroxybenzoyl]benzoic acid hexyl ester absorbs ultraviolet radiation, preventing it from penetrating the skin and causing damage. The compound also acts as an antioxidant, protecting cells from oxidative stress.</p>

<p>2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide is a carboxamide analog of dibucaine. It is synthesized from chloroacetyl chloride and isatin in the presence of sodium hydroxide. The synthesis has been scaled to an industrial level. 2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide has been shown to have analgesic properties, similar to those of dibucaine. Radiolysis of this compound gives a carboxylic acid and a heterocyclic ring product.</p>

<p>4-Amino-5-methoxy-2-methylbenzenesulfonic acid is a compound that has been used as an additive to analytical reagents in order to improve their sensitivity. This compound is used as the sodium salt, which is water soluble and has a high degree of reproducibility. 4-Amino-5-methoxy-2-methylbenzenesulfonic acid has also been used for the validation of analytical methods, including calibration and cytotoxicity testing. The validation procedure includes colorants, spectra analysis, impurities, and solvents.</p>

<p>5-Chloro-2-nitrodiphenylamine is a synthetic dyestuff that belongs to the class of acridones. It can be used as an anti-epileptic drug, although it has not been approved for this use in any country. 5-Chloro-2-nitrodiphenylamine is manufactured by reacting a 6-carboxylic acid with an organic solvent and ammonolysis. This chemical is also known as 6'-chloroacridone and is used in the production of dyes and pigments. The manufacturing process produces impurities such as chloride, which must be removed by evaporation. Nitro groups are introduced during the manufacturing process to improve the dye's stability and color fastness under light exposure.</p>

<p>5-Aminopyridine-3-carboxylic acid (5APC) is a structural analog of nicotinic acid that has been shown to have anti-inflammatory effects. 5APC inhibits the production of inflammatory cytokines, such as IL-10 and IL-17, by inhibiting the activation of NFκB and MAPK pathways. This drug also has significant inhibitory activities against dextran sulfate sodium (DSS)-induced acute colitis in experimental models. 5APC is thought to act by interrupting the assembly of p38 mitogen activated protein kinase (MAPK) and nuclear factor kappa B (NFκB) signaling complexes.</p>

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<p>4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol sulfate dihydrate (benserazide) is a cholinergic agent that has been shown to increase the release of acetylcholine by acting as an agonist at nicotinic receptors. It increases the amount of acetylcholine released in the brain and can be used for the treatment of Alzheimer's disease. Benserazide has also been shown to have a depressant effect on the respiratory system, which can be beneficial for lung diseases. This drug also has anti-inflammatory properties and can inhibit growth factor synthesis.</p>

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<p>cis-4-Aminocyclohexanecarboxylic acid methyl ester hcl is a chemical compound that is used in research and industry. It is an efficient isomer of 4-aminocyclohexanecarboxylic acid methyl ester hydrochloride. cis-4-Aminocyclohexanecarboxylic acid methyl ester hcl has been used as a model for the study of glimepiride, an insulin secretagogue, and has been shown to be active against Toxoplasma gondii.</p>

<p>4-Amino-3-methoxypyridine (4AMMP) is a naturally occurring amino acid that can be found in the nuclei of innervated tissues. It is an inhibitor of the enzyme tyrosine hydroxylase and inhibits the synthesis of catecholamines. The concentration of 4AMMP in blood was measured by radioactivity. This agent has been used for studies on the thalamic nucleus and cortex, as well as for measuring catecholamine levels in tissue homogenates.</p>

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<p>Vasopressin is a peptide hormone that regulates water balance. It is synthesized in the hypothalamus and stored in the posterior pituitary gland, from where it is released when blood pressure falls. Vasopressin binds to V1 receptors in the kidney and vascular smooth muscle cells, causing vasoconstriction and increased blood pressure. Vasopressin also stimulates phosphatidic acid synthesis and hypotension, which are mediated through V2 receptors. Vasopressin has been found to be effective against cardiac arrest and myocardial infarction in animals. This drug has also been shown to stimulate the paraventricular nucleus of the hypothalamus and inhibit sympathetic activity in ganglia.</p>

<p>N-Methoxymethyl-N-(trimethylsilylmethyl)benzylamine is a chiral, electron deficient reagent that reacts with aldehydes and boronic esters to form products with high chemical yields. This compound can be used as a catalyst for acylation reactions, such as the synthesis of p-nitrophenol. N-Methoxymethyl-N-(trimethylsilylmethyl)benzylamine is synthesized by the reaction of trifluoroacetic acid and an amine, followed by chloroformate displacement. The product is then reacted with acylating agents in the presence of catalysts.</p>

<p>3-(Boc-amino)pyridine is a glycine derivative with a trigonal, chelate ring. It can be hydrolyzed by acid to form 3-aminopyridine. 3-(Boc-amino)pyridine has been shown to react with trimethyltin chloride to form an intramolecular complex in the presence of alkyllithiums. This reaction proceeds through lithiation and methylation of the carboxyl group of 3-(Boc-amino)pyridine. The interaction between 3-(Boc-amino)pyridine and trimethyltin chloride forms an antiaromatic six membered ring that resembles a benzene molecule.</p>

<p>Desmopressin is a synthetic analogue of vasopressin, which is used to treat disorders associated with insufficient secretion of vasopressin. It has been shown that desmopressin binds to the vasopressin V2 receptor subtype and stimulates the release of arginine-vasopressin in corticotropin-releasing hormone (CRH)-treated rat pituitary cells. This stimulation was mediated by a residue on the Cys1,b-cyclohexyl residue. The binding of desmopressin to this site was demonstrated in vitro using binding experiments on rat brain synaptosomes. Desmopressin has also been shown to stimulate ovulation in rats and humans, and it has been shown to be effective for treating nocturnal enuresis in children.</p>

<p>Tetra-n-propylammonium hydrogen sulfate (TPAS) is a pharmaceutical dosage that consists of tetra-n-propylammonium ions and hydrogen sulfate anions. It has a diameter of about 2 nm, and can be detected by fluorescence techniques. TPAS has shown to have pharmacologic activities, including the ability to react with hydrogen fluoride in solution to form a precipitate that can be used as a sample preparation reagent. TPAS also has been shown to produce dehydrating effects on chloride in an alicyclic system.</p>

<p>1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a lipid molecule that can induce phase transition in aqueous solutions. DLPE is an active ingredient in nonsteroidal anti-inflammatory drugs and has been shown to inhibit the activity of enzymes such as cyclooxygenase and lipoxygenase. DLPE also inhibits the growth of infectious organisms such as Escherichia coli and HIV by inhibiting receptor activity. DLPE binds to receptors on the surface of cells, which prevents these cells from releasing inflammatory cytokines.</p>

<p>5-Amino-2-methoxyisonicotinic acid is a carboxylic acid that is used in the synthesis of aminopyridines. The compound can be synthesized from formamidine acetate and diethyl dicarbonate. This process involves lithiation, followed by addition of an amine and finally conversion to the desired product with formamidine acetate. 5-Amino-2-methoxyisonicotinic acid can also be synthesized from formamide and diethyl ether. 5-Amino-2-methoxyisonicotinic acid is an analog of 2,4,6-trimethylaniline and has been shown to have similar properties to this compound, including strong basicity.</p>

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<p>Intermediate in the synthesis of bictegravir</p>

<p>2-Bromoethylamine HBr is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-bromoethylamine. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine HBr has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives. It also has the ability to form body tissue (e.g., papillary) and can be used as an experimental model for studying necrosis.</p>

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<p>N-Methyl-N-boc-aminopropan-3-ol is a fine chemical with CAS No. 98642-44-5 that is used in the synthesis of complex compounds, as a reagent for research chemicals, and as a speciality chemical. It is also used in the synthesis of versatile building blocks, reaction components and scaffolds. N-Methyl-N-boc-aminopropan-3-ol has a high quality and can be used as a versatile intermediate or a useful scaffold.</p>

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<p>4-Aminoacetophenone is an inhibitor of the enzyme acetylcholinesterase and it is used as an insecticide. It inhibits the enzyme by forming hydrogen bonding interactions with the active site. The inhibition of this enzyme leads to paralysis and death in insects. 4-Aminoacetophenone has been shown to have anti-cancer effects in vitro, which may be due to its ability to inhibit glycoside hydrolases and amine oxidases that are involved in cancer development. The compound also has a thermal expansion coefficient that is comparable to other polymers used in drug delivery systems.</p>

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<p>4-Aminobenzocyclobutene is a monomer that can be used as a crosslinker. It has been shown to have magnetic properties and is soluble in organic solvents such as dioxane and dichloromethane. 4-Aminobenzocyclobutene readily reacts with paraformaldehyde to form the corresponding paraformaldehyde resin, which is insoluble in water and can be used for the preparation of coatings or adhesives. The hydrosilylation reaction between 4-aminobenzocyclobutene and 3-chloropropyl trimethoxysilane leads to the formation of an aminosilane resin, which exhibits a low water absorption rate and high thermal expansion coefficient. This material can also be used for coating or adhesive applications.</p>

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<p>Caerulein is a hormone that has been shown to have cardiotoxic effects. It is a potent agent that stimulates the release of pancreatic enzymes and causes an increase in the concentration of glucose in blood plasma. Caerulein ammonium salt is used as a pharmacological agent for the treatment of acute pancreatitis and other inflammatory diseases, such as myocardial infarct and infectious diseases. The compound has also been shown to be effective in experimental models of infectious diseases, such as acute pancreatitis.</p>

<p>4-(Phenylazo)diphenylamine is a phenylazodiphenyl amine that is soluble in nonpolar solvents. It has been used as a dye for the detection of heavy metals, such as mercury and lead. This compound can be synthesized by trimerization of nitrobenzene with ammonia and phenol in acidic conditions. 4-(Phenylazo)diphenylamine has been used for the detection of chloride ions, boron nitride, or other impurities in pharmaceutical products due to its high sensitivity.</p>

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<p>Fmoc-4-(Boc-amino)-L-phenylalanine is a useful building block, which is used in the synthesis of complex compounds and research chemicals. It is also a reaction component in the synthesis of compounds. Fmoc-4-(Boc-amino)-L-phenylalanine has CAS No. 174132-31-1 and can be used as a versatile building block to produce high quality reagents.</p>

<p>(2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamideacetate (BAP) is a skin care product that can be applied topically to the skin. BAP is an amino acid derivative that has been shown in clinical studies to hydrate the skin. It acts as a humectant and binds to water molecules, thus increasing the moisture content of the skin. This product also has antioxidant and anti-inflammatory properties, as well as anti-aging effects. BAP is often used in cosmetic products for its film forming properties and ability to form polymeric films on the surface of cells.</p>

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<p>DL-3-Amino-3-phenylpropionic acid is an amino acid that is synthesized by the reaction of malonic acid and ethyl ester. This compound is a competitive inhibitor of the enzyme pyruvate carboxylase and inhibits this enzyme in the conversion of pyruvic acid to acetyl CoA, which plays a key role in metabolism. DL-3-Amino-3-phenylpropionic acid has been shown to inhibit the growth of bacteria such as Escherichia coli, Salmonella typhimurium and Staphylococcus aureus. The inhibition of pyruvate carboxylase by DL-3-Amino-3-phenylpropionic acid prevents the production of acetaldehyde from pyruvate, which is toxic to cells.</p>