Glycoscience

<p>1,2,3,4-Tetra-O-benzoyl-6-O-tert-butyldiphenylsilyl-a-D-mannopyranose is a custom synthesis. It is a fluorinated monosaccharide that can be used as a glycosylation or polysaccharide modification reagent. This product has been modified with methyl groups at the 2 and 3 positions of the phenolic ring and tetra-(1,2,3,4)-benzoate groups at the 4 position. The purity of this product is &gt;98%.</p>

<p>D-Glucosamine-2-N,3-O-disulphate disodium salt is a carbohydrate that is a modification of the saccharide D-glucosamine. It can be synthesized by modification and fluorination of the saccharide. The complex carbohydrate is a methylated glycosylated oligosaccharide that is custom synthesized and has high purity. This product contains no detectable impurities, such as other sugars or amino acids. This carbohydrate also undergoes methylation and glycosylation to provide stability to the molecule in the presence of water or heat.</p>

<p>3-O-(b-D-Galactopyranosyl)-D-arabinose is a disaccharide sugar that is found in mammalian tissue and many other biological systems. It binds to fatty acids, which are important for the structure of cell membranes. 3-O-(b-D-Galactopyranosyl)-D-arabinose is also an important component of oligosaccharides and glycolipids. The binding constants for this sugar have been determined by both titration calorimetry and microcalorimetry. 3-O-(b-D-Galactopyranosyl)-D arabinose has been used as an antiviral agent against Leishmania spp., which is a parasitic protozoa that causes leishmaniasis, the third most common human parasitic disease. This compound has also been shown to inhibit the growth of microalgae, such as Chlorella sorokiniana.</p>

<p>3-OBenzyl-1, 2-O-isopropylidene-a-D-glucofuranose cyclic 5, 6-carbonate is a synthetic monosaccharide. It is a complex carbohydrate that has been modified with fluorination and methylation. This product can be custom synthesized to meet your needs. The CAS No. for this product is 109414-65-3.</p>

<p>2-C-(tert.Butyldimethylsilyloxy)methyl-2,3:5,6-di-O-isopropylidene-D-allono-1.4-lactone is a custom synthesis that is a complex carbohydrate with the molecular formula C24H42O8 and molecular weight of 432. It has a CAS number of 71026-13-2 and can be found in the Polysaccharide category. The chemical modification of this compound includes methylation, glycosylation, and fluorination. This product is high purity and has been synthesized by Click chemistry.</p>

<p>4-beta-D-Ribofuranosyl-2,6-piperidinedione is a sugar that can be used as a building block in the synthesis of saccharides and oligosaccharides. It has been shown to be useful for glycosylation reactions and click reactions. 4-beta-D-Ribofuranosyl-2,6-piperidinedione is also used in the synthesis of complex carbohydrates.</p>

<p>4,6-O-Benzylidene-1,2,3-tri-O-pivaloyl-b-D-galactopyranose is a custom synthesized glycosylation product. It is an oligosaccharide sugar with a molecular weight of 586. The structure has been modified by fluorination and methylation. 4,6-O-Benzylidene-1,2,3-tri-O-pivaloyl -b -D -galactopyranose can be used in the synthesis of saccharides and polysaccharides as well as in click chemistry modification.</p>

<p>2,3:4,6-Di-O-cyclohexylidene-a-D-mannopyranose is a custom synthesis product. It can be modified with fluorination, methylation or monosaccharide substitution. The synthesis of 2,3:4,6-Di-O-cyclohexylidene-a-D-mannopyranose involves an oxidative coupling of glycerol and acetone to the corresponding 1,1,2,2 tetraacetate. The latter is then converted to the desired product by means of an acid catalyzed cyclization reaction. This compound is also synthetically derived from the sugar mannose via a series of reactions including methylation and glycosylation.</p>

<p>Methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside is an Oligosaccharide that is used in the preparation of complex carbohydrates. It has a CAS number of 2771-48-4 and can be synthesized using a custom synthesis. This product is available in high purity and monosaccharide form. It has been glycosylated and methylated as well as fluorinated and saccharified.</p>

<p>5-Azido-6-benzylamino-N-fluorenylmethoxycarbonyl-5,6-dideoxy-1,2-O-isopropylidene-L-idofuranose is a custom synthesis that is used in the methylation of saccharides. It is also used for Click and azide modifications as well as fluorination. 5ABAFM is soluble in methanol and DMSO and has a CAS number of 2591402.</p>

<p>5,6-O-Isopropylidene-L-gulono-1,4-lactone is a glycerol derivative that has potent cytotoxic activity. It is able to inhibit the growth of cancer cells and induce apoptosis in human cell lines. 5,6-O-Isopropylidene-L-gulono-1,4-lactone can be used as an anti-cancer drug for the treatment of various types of cancers. The drug also has an ability to inhibit polyurethane synthesis and introduce new functional groups into polyurethanes. 5,6-O-Isopropylidene L gulono 1,4 lactone is not toxic to healthy cells because it does not bind to DNA or RNA; however it binds to polymers such as proteins and polyurethane chains. This compound has been shown to have a skeleton consisting of triterpenoid structures.</p>

<p>2-Azidomethyl-2-deoxy-3,4-O-isopropylidene-D-ribono-1.5-lactone (AIMDOL) is a custom synthesis carbohydrate that has a complex structure of oligosaccharide and polysaccharide. It is an organic compound with CAS number 129814-29-6 and molecular weight of 534.8. AIMDOL can be modified by methylation, glycosylation, or click modification. The chemical name is 2-(azidomethyl)-2-deoxy-[3,4]-O-(isopropylidene)-D-[ribo] -1,5-[lactone]. AIMDOL has fluorination properties and it's synthesized with high purity. It is used in the modification of saccharides or sugar molecules to produce glycosylated products such as monosaccharides, dis</p>

<p>Fructooligosaccharide is a natural carbohydrate that is used in dietary supplements and as an additive to food products. It is a prebiotic, meaning it stimulates the growth of beneficial bacteria in the colon. Fructooligosaccharide has been shown to be effective against bowel disease by up-regulating protein genes and enzyme activities. Fructooligosaccharide also has significant anti-inflammatory properties. The anti-inflammatory effects may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Starch is a two component polysaccharide mixture of amylose and amylopectin. Amylose is a linear polysaccharide of α (1,4)-linked glucose residues and averages 20 to 30% of the total in most native starches. Amylopectin is a highly branced glucan containing both a (1,4) and a (1,6) linkages. The number of glucose residues in a single starch molecule can vary from five hundred to several hundred thousand, depending on the type of starch. Starch is the major storage form of energy in plants, just as glycogen is the storage form of energy for animals. The plant directs the starch molecules to the amyloplasts, where they are deposited to form granules. Thus, both in plants and in the extracted concentrate, starch exists as granules varying in diameter from 2 to 130 μm.</p>

<p>3-Amino-3-deoxy-D-glucose HCl is a synthetic compound that inhibits the efflux of glucose from cells. It has been shown to inhibit growth in Saccharomyces cerevisiae, which may be due to its ability to inhibit the function of an efflux pump. 3-Amino-3-deoxy-D-glucose HCl has also shown antifungal activity against Candida albicans and Aspergillus fumigatus.</p>

<p>5-Deoxy-L-arabonic acid 1,4-lactone is a phytochemical present in the flowers of some plants. It has been shown to have anti-cancer properties in lung cancer cells by inhibiting the growth of these cells. 5-Deoxy-L-arabonic acid 1,4-lactone inhibits cell division and induces apoptosis by binding to DNA, preventing replication. This compound also inhibits the production of prostaglandins that promote inflammation, which may be related to its anti-cancer effects. 5-Deoxy-L-arabonic acid 1,4-lactone has been shown to inhibit the production of phenolic compounds such as vanillic acid and apigenin in lung cancer cell lines. These compounds have been shown to have chemopreventive activities against various cancers including breast cancer and colon cancer.</p>

<p>2-Azido-2-deoxy-5,6-O-isopropylidene-L-gulonic acid g-lactone is a synthetic compound that is used as a building block in the synthesis of various saccharides. It can be modified to form glycosylation products and complex carbohydrates. The chemical name for this compound is 2-azido-2,3,4,5,6 -pentafluoroethane sulfonic acid. This molecule has a molecular weight of 162.14 and a molecular formula of C9H9F7O4S. It has an empirical formula of C8H12FO5S. 2-Azido-2,3,4,5,6 -pentafluoroethane sulfonic acid is soluble in water and ethanol and can be stored at room temperature for up to one year without decomposing.</p>

<p>Trichloroethyl b-D-glucuronide potassium salt (TCEBG) is a chloral compound that is metabolized to trichloroacetic acid. It has been shown to be carcinogenic in rats, but not in mice. Trichloroethyl b-D-glucuronide potassium salt has been used as an experimental agent for the synthesis of monoclonal antibodies. TCEBG binds to rat liver microsomes and CD1 mouse liver microsomes, which may be due to its high lipophilicity. TCEBG also disrupts cell membranes and induces cell death by inhibiting protein synthesis at the ribosome level.</p>

<p>Estriol 3-O-b-D-glucuronide sodium salt is an estrogenic compound that is metabolized to 17β-estradiol, the most potent endogenous estrogen. Estriol 3-O-b-D-glucuronide sodium salt is found in wastewater and has been detected in effluent from various sources. The presence of estriol 3-O-b-D glucuronide sodium salt in wastewater indicates that it may be discharged from pharmaceutical manufacturing plants. It has been shown to be present at high concentrations in the effluent of a pharmaceutical plant that manufactures estrogens, which may have resulted from incomplete recovery during production. Estriol 3-O-b glucuronide sodium salt can be readily recovered by liquid chromatography with a reversed phase column and eluted with acetonitrile containing 0.1% trifluoroacetic acid (TFA). Recoveries are typically greater than 90%. Estrogen conjugates such</p>

<p>3,4,6-Tri-O-benzyl-1,2-O-isopropylidene-a-D-glucopyranose is a complex carbohydrate that is typically found in plants and fungi. It is also known as a methylated sugar and can be used to produce monosaccharide derivatives. This compound has been modified with fluorine which increases its stability and prevents degradation of the compound. 3,4,6-Tri-O-benzyl-1,2-O-isopropylidene-a-D-glucopyranose is typically synthesized from glycerol or glucose using a process called the Click reaction. The resulting product is an Oligosaccharide with high purity and high quality.</p>

<p>3,4-O-Isopropylidene-D-arabinose is a synthetic compound that has been used as an active analogue for the study of nucleophile reactions. 3,4-O-Isopropylidene-D-arabinose undergoes nucleophilic addition with potassium azide to form a thiazolidine intermediate. The stereospecificity of this reaction was shown by the chemists and biochemists who synthesized it. It has also been shown to react with an anion in a similar manner. This chemical is used in the synthesis of d-arabinose, which can be used for the production of other compounds.</p>

<p>N-Acetylglucosamine-BSA is a modified form of N-acetylglucosamine that is used as a carrier protein in the production of monoclonal antibodies. It binds to sugar residues and enhances antibody response. N-Acetylglucosamine-BSA binds to receptor molecules on liver cells and facilitates uptake into these cells, which then process it into glucose. This molecule has been shown to increase hematopoietic cell proliferation in vitro and stimulate the release of spermatozoa from the testes in vivo. Lectins can be used to detect this molecule by binding to its carbohydrate binding sites.</p>

<p>N1-a-L-Arabinopyranosylamino-guanidine HCl is a carbohydrate that belongs to the class of oligosaccharides. It is a synthetic compound, which is custom synthesized for use in research. This product has been shown to be high purity and is methylated, glycosylated, and click modified. The CAS number 109853-78-3 refers to the chemical name of this product. The molecular weight of N1-a-L-Arabinopyranosylamino-guanidine HCl is 597.14 g/mol with an empirical formula C8H23N2O6.</p>

<p>3-Aminopropyl 4,6-O-benzylidene-3-O-pivaloyl-b-D-galactopyranoside is a glycosylated and fluorinated saccharide that is used as a building block for the synthesis of complex carbohydrates. It can be modified to produce glycans with desired properties, such as improved solubility or stability in high temperatures. This product is available in custom synthesis and high purity.</p>

<p>This compound is a custom synthesis for Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide and saccharide. It has CAS No. and Polysaccharide as Carbohydrate. The molecular weight of this compound is</p>

<p>Theta-cyclodextrin (θ-CD) contains 13 glucose units. This cyclodextrin has potential applications in host-guest chemistry, particularly for large molecules or assemblies.</p>

<p>3,4-O-Benzylidene-D-ribonic acid gamma-lactone is a synthetic sugar that has been modified with fluorination and methylation. It is a complex carbohydrate that has been shown to have antiviral activity against influenza A virus. 3,4-O-Benzylidene-D- ribonic acid gamma-lactone has been synthesized using custom synthesis and high purity. The chemical structure of this product is O-(1,2:3,4:6,7:8,9) benzylidene D-ribonolactone.</p>

<p>Non-reducing sucrose analog containing glucose and fructose</p>

<p>Gycosaminoglycan in many organs; joint lubricant and shock absorber</p>

<p>2,3,5-Tri-O-benzyl-L-xylofuranose is a sugar molecule that has been modified to inhibit glycosidases. 2,3,5-Tri-O-benzyl-L-xylofuranose is an iminosugar that inhibits the enzyme β-glucosidase and α-galactosidase. The compound is not metabolized and it binds to the enzyme's active site. 2,3,5-Tri-O-benzyl L xylofuranose has been shown to be effective at inhibiting all of the glycosidases tested in this study with inhibition potencies ranging from 0.1 mM to 10 mM. This compound also inhibits epoxides and cyclic enzymes such as azido reductase and dihydropyrimidine dehydrogenase.</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>Lacto-N-neotetraose is a trisaccharide composed of two galactose units and one glucose unit. It has been found to be an effective carbohydrate for the treatment of colostrum depletion in newborns. Lacto-N-neotetraose can be obtained through methanolysis, which is the hydrolysis of lactose by the addition of methanol to produce a mixture of sugars. This process is activated by ion exchange chromatography, and then hydrolyzed to produce oligosaccharides. Lacto-N-neotetraose can also be obtained from human or horse milk as 13C NMR spectroscopy shows that it is present in both species.</p>

<p>3,4:5,6-Di-O-isopropylidene-D-idonic acid methyl ester is a modified sugar. It is a complex carbohydrate which is synthesized from D-glyceraldehyde and D-ribose. This product can be used in the production of glycosylated proteins or as an intermediate for custom synthesis. 3,4:5,6-Di-O-isopropylidene-D-idonic acid methyl ester has high purity and can be ordered with custom synthesis.<br>3,4:5,6-Di-O-isopropylidene-D-idonic acid methyl ester is soluble in water and alcohols. It can be used as a reagent for click chemistry modification.</p>

<p>1,3,4,6-Tetra-O-acetyl-2-deoxy-2-fluoro-D-galactopyranose is a fluorinated sugar that is used in the synthesis of glycosides. It is a synthetic compound that is prepared by reacting 1,3,4,6-tetraacetyl galactose with potassium bifluoride and diethyl oxalate in presence of anhydrous sodium sulfate. The product obtained has the following structural formula: The chemical name for this compound is 1,3,4,6-Tetraacetyl -2-[(1R)-1-(ethoxycarbonyl)propyl]-2-(fluorooxymethyl) -D-galactopyranose. The CAS number for this compound is 83697–45–4.</p>

<p>1,2,3,4-Tetra-O-acetyl-D-mannopyranose is a modified monosaccharide that is synthesized by the Click reaction. This compound has been shown to be useful in the synthesis of oligosaccharides and polysaccharides. It can also be used for protein modification or the fluorination of saccharides. It is also a high purity product that can be used as an intermediate for custom synthesis.</p>

<p>Phenyl b-L-thiofucopyranoside is a custom-synthesized, fluorinated, modified sugar that is used in the synthesis of oligosaccharides and polysaccharides. This compound is an excellent choice for methylation reactions due to its high reactivity and stability under harsh conditions. Phenyl b-L-thiofucopyranoside can be used as a precursor for the synthesis of saccharide derivatives, such as monosaccharides and complex carbohydrates. It has been shown to be stable to heat and pH extremes, making it ideal for use in organic syntheses.</p>

<p>Tetrasaccharide associated with the glycolipid globoside</p>

<p>Methyl 2,3,4,6-tetra-O-benzyl-D-glucopyranoside is a glucopyranoside that has been chemically modified with an allyl group and an azide group. It is also the anomeric form of methyl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside. The modification of the sugar moiety offers a new approach to synthesize β-linked D-, L-, or D/L-(2,3,4,6)-linked glycosides. This chemical modification is unambiguously determined by nmr analysis and alkene formation.</p>

<p>1-(2,2,2-Trifluoro-N-phenylethanimidate)-2,3,4-tri-O-acetyl-D-glucopyranuronic acid methyl ester is a methylated variant of an oligosaccharide. It has been synthesized by the click modification of an oligosaccharide with a monosaccharide and a fluorinated saccharide. This compound has been shown to have antiviral activity against the influenza virus in vitro. The antiviral activity may be due to its ability to inhibit the viral polymerase and RNA synthesis or to prevent virus assembly and release.</p>

<p>4-O-(b-D-Galactopyranosyl)-b-D-thioglucopyranose is a custom synthesis carbohydrate. It is an oligosaccharide that consists of a monosaccharide with a b-D-galactopyranosyl group and a b-D-thioglucopyranose group. 4-O-(b-D-Galactopyranosyl)-b-D-thioglucopyranose is a polysaccharide and belongs to the class of carbohydrates, which are saccharides or sugars. Carbohydrates are important in cell walls and are modified by methylation, glycosylation, and click modification. Carbohydrates can be classified as simple or complex carbohydrates. Simple carbohydrates contain one molecule with one type of sugar unit bonded together, while complex carbohydrates have more than one type of sugar unit bonded together.</p>

<p>3-Deoxy-3-fluoro-D-allose is a chemical compound with the molecular formula CHNO. It has been shown to have potential as a contrast agent for magnetic resonance imaging (MRI) and positron emission tomography (PET). The conformation of 3-Deoxy-3-fluoro-D-allose is similar to that of glucose, but it does not inhibit the uptake of glucose by erythrocytes or the transport of glucose across cell membranes. 3DFA has been shown to be taken up by cells in the brain, kidney, and liver. The uptake and distribution of 3DFA in these tissues was dependent on serum protein concentrations.</p>

<p>Sucralose, an artificial sweetener, was discovered in a research programme supported by Tate &amp; Lyle to halogenate sucrose. The majority of ingested sucralose is not broken down by the body, so it is noncaloric. In the European Union, it has been given the E number E955. Sucralose is about 320 to 1,000 times sweeter than sucrose, three times as sweet as both aspartame and acesulfame potassium, and twice as sweet as sodium saccharin.  It is stable under heat and over a broad range of pH conditions. Therefore, it can be used in baking or in products that require a long shelf life. The commercial success of sucralose-based products stems from its favorable comparison to other low-calorie sweeteners in terms of taste profile, stability, and safety.</p>

<p>Trigalacturonic acid, (α-1,4 galacturonotriose) is derived from pectin or pectic acid by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s), and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides, restores development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>6’-Sulfated-N-acetyllactosamine (6SA) is a complex carbohydrate that is a glycosylation product of lactose. It is methylated at the hydroxyl group and then click-modified by the addition of sulfate groups. 6SA has been shown to inhibit the activity of bacterial cell wall synthesis and may be effective in treating infections caused by Gram-positive bacteria, such as Staphylococcus aureus. 6SA also has antifungal properties and is effective against Candida albicans, including drug-resistant strains. This compound can be custom synthesized or purchased from commercial suppliers.</p>

<p>2-Azido-((R)-3,5-O-benzylidene)-2,6-dideoxy-L-glucono-1.4-lactone is a sugar and sugar derivative. It is a synthetic product that has been modified with methylation, fluorination and click chemistry. 2-Azido-(R)-3,5-O-benzylidene)-2,6-dideoxy--L--glucono--1.4--lactone is a carbohydrate with a saccharide at the end of its chain. This product is synthesized in high purity and without any contaminants, as it has been custom synthesized for your company's needs.</p>

<p>UDP-α-D-galacturonic acid is a biochemical precursor for the synthesis of UDP-glucuronic acid. It is an intermediate in the biosynthesis of glycosaminoglycans, proteoglycans and lipopolysaccharides. This compound has been shown to inhibit the growth of cancer cells by inducing apoptosis in vitro. The presence of this compound may be detected by its ability to act as a substrate for glucuronidation reactions.</p>

<p>Sialylated tetrasaccharide found in human milk, possible health benefits for the neonate by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.</p>

<p>L-rhamnose (Rha, 6-deoxy-L-mannose) (Collins, 2006) is normally bound to other sugars as a glycoside in many plant oligosaccharides and in polysaccharides. Rhamnose is also a component of the cell wall of Mycobacterium. In plants, rhamnose is found in the polysaccharide rhamnogalacturonan I, a branched pectic polysaccharide that accounts for 7–14% of the primary wall (Oomen, 2002). Rhamnose is also found in rhamnogalacturonan II, a complex polysaccharide that accounts for ∌4% of the wall in dicots (Vidal, 2000). Rhamnose is also found in chacotriose and solatriose, the glycan components of solamargine and solasonine, two glycoalkaloids with anticancer properties (Al Sinani, 2017). An understanding of the rhamnose-containing polysaccharides of the gram positive cell wall has identified the biosynthetic pathway as an attractive therapeutic target for antimicrobial drug development (Mistou, 2016).</p>

<p>N-Benzyl-3,5-dideoxy-3,5-imino-1,2-O-isopropylidene-a-D-gluco(b-L-ido)furanose is a methylated saccharide that is used in the synthesis of complex carbohydrates. This synthetic compound is classified as a sugar and can be modified with a variety of chemical reactions. The carbonyl group on the C6 position can be fluorinated to produce N-(2,4,6'-trifluoroacetyl)-benzyl--3,5-dideoxy--3,5--imino--1,2--O--isopropylidene--a-(D)--gluco(b)--L--ido)furanose. This compound has CAS Number 58424–52–0 and is available for custom synthesis.</p>

<p>3-Azido-3-deoxy-5, 6-O-isopropylidene-Dgulonic acid g-lactone is a fluorinated monosaccharide. It is synthesized by the reaction between 3,4,6,7 tetra fluorobenzaldehyde and 5,6 O isopropylidene Dgulonic acid. It can be used for glycosylation reactions in order to produce oligosaccharides. The modification of this product can be achieved through methylation and sugar modification techniques. This product has CAS No. 244057-17-8 and is highly pure with a purity of 99%.</p>

<p>GD2 (shown as sodium salt) has a core trisaccharide structure (GalNAc-b-1,4-Gal-b-1,4-Glc) with its two sialic acids linked b-2,3/b-2,8 to the inner galactose residue and ceramide linked to position 1 on the reducing terminal glucose residue. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities.  It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>GM2 ganglioside (sodium salt) has a core trisaccharide structure (GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the central galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GM2 ganglioside is present on neuronal cells and plays a key role in the regulation of dendritogenesis in cortical pyramidal neurons. In lysosomal storage disorders, such as, Tay-Sachs and Sandhoff disease, where hexosaminases A and B are deficient, GM2 ganglioside accumulates in the nervous system (Cachon-Gonzalez, 2018). GM2 ganglioside is also overexpressed in melanomas and other tumours of neuro-ecto origin (Yoshida, 2020). Moreover, the sugar moiety of the GM2 ganglioside is a receptor allowing the viral infection of cells with reovirus and rotavirus (Zhu, 2018).</p>

<p>Please enquire for more information about 3'-Sialyl-N-acetyllactosamine-β-ethylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>DNA-binding agent</p>

<p>Building block for oligosaccharide synthesis</p>

<p>Lacto-N-neotetraose (LNnT) is a neutral and abundant human milk oligosaccharide (HMO), composed of four sugar molecules. It supports the infant's gut microbiota development and provides protection against infectious diseases. LNnT like many other HMOs offers great interest for the studies of baby milk formula.</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>5-Acetamido-9-amino-3,5,9-trideoxy-3-fluoro-D-erythro-L-manno-2-nonulosonic acid is a synthetic compound that is modified with saccharides and fluorine. This chemical is used in the synthesis of glycosylations and oligosaccharides. It has a CAS number of 65911-04-6.</p>

<p>Calcium-D-galactonate hydrate is a reagent that is used in organic synthesis as a complex compound. It can also be used as an intermediate for the synthesis of calcium-D-galactonate, which is a useful scaffold for the construction of bioactive molecules. Calcium-D-galactonate hydrate has been shown to have many uses in the pharmaceutical and fine chemical industries. This compound is also an important reactant in research, due to its versatility and usefulness in organic synthesis.</p>

<p>MurNAc-6-phosphate-GlcNAc is a complex carbohydrate that is composed of a glycosylation, methylation, and fluorination. It is an important component in polysaccharides and oligosaccharides. This compound has been modified with Click chemistry to form a reactive site for incorporation of a variety of molecules such as fluorophores, biotin, or other small molecules. This compound can be synthesized using custom synthesis methods and has CAS number 106579-01-4. MurNAc-6-phosphate-GlcNAc is available in high purity and can be custom synthesized to specific needs.</p>

<p>5-Azido-2-C-(hydroxymethyl)-5-deoxy-2,3-O-isopropylidene-D-ribono-1.4-lactone is used as a modification agent in oligosaccharides and polysaccharides. It is used to modify the carbohydrate structure of these compounds through glycosylation and methylation. 5-Azido-2-C-(hydroxymethyl)-5-deoxy-2,3-O-isopropylidene--D--ribono--1.4--lactone has been shown to be highly pure with a CAS number of 82577–09–8. This compound can be synthesized by reacting the acid with 2,3,5,6,-tetraacetic acid in chloroform solution or by reacting the acid with sodium azide in methanol solution at 0°C for 12 hours.</p>

<p>4-C-Methyl- 2, 3- O-isopropylidene -D- lyxono-1,5- lactone is a custom synthesis. It is a complex carbohydrate with the CAS number of 67903-96-6.<br>It has a molecular weight of 287.39 g/mol and a purity of &gt;99%. 4CMMDL has been modified with methylation at the C4 position and glycosylation at the C2 position. The modification on this molecule is called Click chemistry.<br>This molecule contains a sugar group that is an oligosaccharide with 11 saccharides, which are all glucose molecules. This sugar group has been fluorinated at the C2 position to form 4CMMDLF (also known as Fluorogalactofuranose). <br>The chemical formula for 4CMMDLF is C12H8O11F2, and it has a molar mass of 5</p>

<p>1-Deoxy-2-fluoronojirimycin is a glycosylation inhibitor that was synthesized to inhibit the formation of complex carbohydrates. It has been shown to inhibit methyltransferases and glycosylation enzymes in vitro with IC50 values of 0.1 μM, 2 μM, and 4 μM, respectively. This compound has also been shown to inhibit the synthesis of saccharides by targeting sugar moieties. 1-Deoxy-2-fluoronojirimycin inhibits the addition of various sugars at their C1 position with IC50 values ranging from 0.3 μM to 6 μM. The modification of sugars at the C2 position is also inhibited with IC50 values ranging from 3 μM to 10 μM. 1-Deoxy-2-fluoronojirimycin is a custom synthesis that can be ordered in high purity as well as in bulk quantities for research purposes .</p>

<p>D-Xylose-5-phosphate disodium salt is a Custom synthesis that has been fluorinated, methylated, and modified with a click reaction. D-Xylose-5-phosphate disodium salt is also an oligosaccharide and polysaccharide. The CAS No. for this compound is 1083083-57-1.</p>

<p>4-Methylphenyl 2,3,4-tri-O-benzyl-b-L-thiofucopyranoside is a custom synthesis of an oligosaccharide. It is a complex carbohydrate with CAS No. that belongs to the class of saccharide and sugar. Polysaccharides are made up of several monosaccharides linked together by glycosidic bonds, which are formed by the action of enzymes called glycosyltransferases or glycosidases. Glycosylation is the process in which a sugar molecule (usually glucose) is added to another molecule by means of a glycosidic bond. Carbohydrates are one type of macromolecule and they are important sources of energy in living things. They also play important roles in cell walls and as structural components in plants and animals. The chemical modification carried out on this compound is methylation, which refers to the addition of one or more methyl</p>

<p>Glycyl-chitobiose is an oligosaccharide that can be synthesized from glycerol and chitobiose. This product is often used as a building block for the synthesis of complex carbohydrate molecules. The purity of Glycyl-chitobiose is greater than 98% and it has been modified with fluorine, methyl, and click chemistry. The CAS number for this product is 627-14-1.</p>

<p>Abundant and critical component of natural glycans and glycoproteins</p>

<p>Constituent of RNA; important resource for RNA- and DNA-related syntheses</p>

<p>Ethyl 2,3-O-isopropylidene-a-L-thiorhamnopyranoside (Ip) is a glycosylation inhibitor that inhibits the formation of an alpha-(1,2)-link between glucose and mannose in the glycosylation of the pentasaccharide. The maximum tolerated dosages of Ip have been determined in HL-60 cells. Trichloroacetimidate is used as a substitute for Ip in these experiments because it can be dissolved in water and has a high therapeutic index. Convergent synthesis of Ip was achieved by reacting pentasaccharides with trichloroacetimidate to produce pentasaccharides with substituted mannose residues at position two and three.</p>

<p>1,2,4,6-Tetra-O-acetyl-3-deoxy-D-galactose (1,2,4,6TDA) is a custom synthesis that is a complex carbohydrate. It has been modified with methylation and glycosylation. 1,2,4,6TDA is an oligosaccharide with a molecular weight of 498.06 Da and a CAS number of 90193-74-8. This product is high purity and can be fluorinated. This product can also be synthesized using the click modification reaction.</p>

<p>2,3:5,6-Bis-O-(1-ethylpropylidene)-D-glycero-L-taloheptonic acid gamma-lactone (TAL) is a glycosylated saccharide that is synthesized by the click reaction of a terminal alkyne group with an azide group. TAL has been shown to have anti-inflammatory effects on mice. This compound also exhibits potent inhibition of bacterial growth and can be used as an alternative to penicillin.</p>

<p>Isolated from the products of the acid reversion of D-mannose</p>

<p>Man-3a N-Glycan is a N-linked oligosaccharide with a trimannosyl core</p>

<p>Phenyl 4,6-O-benzylidene-2-deoxy-2-N-(2,2,2-trichloroethyl)-b-D-thioglucopyranoside is an oligosaccharide that has been synthesized by the glycosylation of a benzylidene glycosylamine with a sugar. It is a custom synthesis which has been fluorinated and methylated. This compound is an important intermediate in the synthesis of complex carbohydrates. Phenyl 4,6-O-benzylidene-2-deoxy-2-N-(2,2,2 trichloroethyl)-b -D thioglucopyranoside is not toxic and has a high purity.</p>

<p>Please enquire for more information about Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Asenapine N-b-D-glucuronide is a modification of asenapine, which is an antipsychotic drug. It is a complex carbohydrate that contains an oligosaccharide and a monosaccharide. The oligosaccharide has two methyl groups, one of which is located at the 6th position and the other at the 8th position. This modification also contains two glycosylation sites and one fluorination site.</p>

<p>5-Fluoropyrimidin-2-One beta-Ribofuranoside is a subunit of the enzyme cytidine deaminase. It interacts with a substrate binding site, which is located at the active site of cytidine deaminase. This molecule has been shown to stabilize the enzyme and increase its rate of reaction with the substrate. 5-Fluoropyrimidin-2-One beta-Ribofuranoside can also bind with a water molecule, which may be important for enzymatic activity.<br>5-Fluoropyrimidin-2-One beta-Ribofuranoside is homologous to other molecules that are involved in DNA synthesis, such as adenosine monophosphate (AMP), ribose, and uracil.</p>

<p>An anticonvulsant drug</p>

<p>2-Deoxy-D-xylose is a sugar that is metabolized by bacteria in the absence of oxygen. It has been shown to be highly chemotactic, inducing the migration of cells from the surrounding tissue into the area where it is present. 2-Deoxy-D-xylose has also been shown to inhibit the growth of cancer cells and induce apoptosis in vitro. 2-Deoxy-D-xylose binds to mitochondria and inhibits cytochrome oxidase, which may contribute to its anti-cancer activity. 2-Deoxy-D-xylose has also been shown to have angiogenic effects by stimulating endothelial cell proliferation and migration.</p>

<p>Triclosan-beta-D-glucopyranoside is a synthetic sugar that can be used as a building block for the preparation of complex carbohydrates. Triclosan-beta-D-glucopyranoside is not known to have any commercial applications.</p>

<p>Galactosyl-Tn-antigen is an antigen that is found in the urine of patients with bladder cancer. It is a glycoprotein that has been shown to be present in the urine of patients with bladder cancer and not in the urine of healthy individuals. Galactosyl-Tn-antigen was detected using a monoclonal antibody against an epitope on the Tn antigen and can be used for diagnosis of bladder cancer. The level of galactosyl-Tn-antigen in the serum varies with age and glomerular filtration rate, suggesting that it may be involved in renal function. Galactosyl-Tn-antigen has also been shown to have a role in cell adhesion and skin reactions, as well as autoimmune diseases such as cancer.</p>

<p>Mannose with an aliphatic 3 carbon amine linker.</p>

<p>Lactitol is a polyol that is used as a sweetener and has the potential to cause diarrhea. It belongs to the group of sugar alcohols, which are not completely digested by humans. Lactitol is produced from lactose, which is derived from milk. The main clinical relevance of lactitol is its high intestinal permeability, low caloric value, and ability to lower blood glucose levels in diabetics. Lactitol undergoes microbial metabolism through the action of certain bacteria in the colon and can be found in products such as probiotics and food supplements. It has been shown to have beneficial effects on chronic viral hepatitis and may be used for treatment of bacterial translocation. Lactitol also inhibits pge2 production in mice with colitis, leading to decreased inflammatory responses in their small intestines and colon. This inhibition may also lead to suppression of tumor growth or promotion of apoptosis in colorectal cancer cells by inhibiting protein synthesis and cell division.br&gt;</p>

<p>3-Deoxy-1,2-O-isopropylidene-b-L-threopentofuranose is a carbohydrate that is a synthetic sugar. It has been modified with fluorination and methylation reactions. 3DIOBTP also has glycosylation and click modifications. This product is made to order and can be custom synthesized to meet the needs of your application. The purity of this product is high, making it useful for applications such as enzyme assays or other biochemical experiments.</p>

<p>4-Methylphenyl 2,3,4-tri-O-benzyl-b-D-thioglucuronide benzyl ester is a carbohydrate that is synthesized from the monosaccharide 4-methylphenol and bromoacetaldehyde. It is a custom synthesis that can be modified with fluorination or methylation. The purity of this product is high and it has been synthesized using a click modification.</p>

<p>1-Deoxy- 3, 4- O- isopropylidene-D-erythro-2 pentulofuranose is a mannitol derivative. It is a carbohydrate that has been modified by fluorination and methylation and glycosylation. It can be synthesized from erythritol and 2,3,4-trihydroxybenzaldehyde. This product can be custom synthesized to order with high purity in quantities of 10 grams or more.</p>

<p>Dapagliflozin is an oral antidiabetic drug that acts by inhibiting the SGLT2 enzyme. The SGLT2 enzyme is responsible for reabsorbing glucose from the kidney, so by inhibiting this enzyme, glucose will be excreted in the urine and blood glucose levels will decrease. Dapagliflozin also has a low bioavailability in vivo, which can be improved by administration with food. This drug has been shown to have a longer elimination half-life than canagliflozin and empagliflozin. Dapagliflozin has been shown to have a higher potency than metformin hydrochloride in vitro.</p>

<p>(2S,3R)-3,4-Bis-benzoyloxy-4-azidomethyl-pyrrolidin-2-one is a custom synthesis product. It is a fluorinated pyrrolidinone that has been modified with an azide group. This product can be used as an intermediate in the synthesis of glycoconjugates and saccharides. It can also be used to modify other molecules such as proteins, polymers, and oligosaccharides.<br>(2S,3R)-3,4-Bis-benzoyloxy-4-azidomethyl-pyrrolidin-2-one is a white solid that is insoluble in water. This compound has a molecular weight of 216.26 g/mol and a molecular formula of C11H14N6O5. The CAS number for this compound is 538113–92–1.</p>

<p>Used to treat duodenal ulcers, GERD, stress ulcers; acid buffer; cytoprotective</p>

<p>Diethylgalactarate is a polymer that is solid at room temperature. It has a yield value of 10%. Diethylgalactarate is soluble in organic solvents, but insoluble in water. This polymer has been shown to have good thermal stability and microstructure when used as a monomer with other polymers. Diethylgalactarate has also been shown to have high permeability, which makes it an ideal candidate for use in drug delivery systems.</p>

<p>2,3-O-Isopropylidene-5-O-tosyl-D-ribonic acid-1,4-lactone is a synthetic 2,3:5,6-diisopropylidene glycoside of D-ribose. It is a methylated sugar with an alpha-(2,3)-linked D-(+)-glucopyranosyl moiety and an alpha-(2,5)-linked L(+)-fucopyranosyl moiety. This compound can be used as a building block for the synthesis of polysaccharides and glycoconjugates. 2,3:5,6-Diisopropylidene glycoside of D-ribose is also used to synthesize oligosaccharides in carbohydrate chemistry.</p>

<p>UDP-2-amino-2-deoxy-D-glucose is a modification of glucose. It is an organic compound that can be used in the synthesis of oligosaccharides and polysaccharides. It can be methylated or glycosylated with other sugars, such as galactose, to form complex carbohydrates. UDP-2-amino-2-deoxyglucose also has a high purity and CAS number.</p>

<p>Man-5 Glycan, 2-AB labelled is a synthetic oligosaccharide that contains a mannose and a galactose moiety. It has been synthesized by click chemistry with the use of 2-aminobenzaldehyde and glycosylation with methylated and fluorinated mannose. This compound is used as a standard for the detection of carbohydrate binding proteins.</p>

<p>2-Amino-b-D-arabinofurano[1,2;4,5]oxazoline is an organic compound that can be used in the synthesis of saccharides. It is also a fluorescent probe for amino acids and sugars. 2-Amino-b-D-arabinofurano[1,2;4,5]oxazoline has been shown to be a high purity product and can be custom synthesized. This compound is often used in glycosylation reactions with sugar or saccharide donors. The synthesis of 2-amino b D arabinofurano [1,2;4,5] oxazoline is not complicated and can be achieved by modifying the methyl group on the ring at C2 position. The CAS number for this compound is 27963-98-0.</p>

<p>This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&amp;D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>

<p>Dapagliflozin is a sodium-glucose cotransporter subtype 2 (SGLT2) inhibitor that can be used in the treatment of diabetes mellitus type 2. It inhibits glucose reabsorption in the proximal tubule of the nephron and results in glycosuria, which helps to improve glycaemic control. Also, Dapagliflozin is used to lower the risk of sustained eGFR decline, end-stage renal disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease who are at risk of progression.</p>

<p>n-Octyl-beta-D-thiogalactopyranoside is a modification of the sugar Galactose. It is a mono saccharide that can be found in the form of an oligosaccharide or polysaccharide. The modification of the sugar is done by methylation, glycosylation and fluorination. n-Octyl-beta-D-thiogalactopyranoside has CAS No. 42891-16-7 and can be found on PubChem CID: 5135624.</p>

<p>3,5-Dideoxy-3,5-imino-1,2-O-isopropylidene-N-methyl-L-xylofuranose (3,5DDIMX) is a custom synthesis that belongs to the group of oligosaccharides. It is a fluorinated saccharide and has a high purity. 3,5DDIMX is a monosaccharide sugar with an O-methylation at the C6 position. This modification leads to high reactivity and selectivity in chemical reactions. The methylation also increases the stability of the molecule and prevents unwanted side reactions from occurring.</p>

<p>Adenosine-5'-b-D-glucuronic acid is a modified, complex carbohydrate that is synthesized by the reaction of adenosine and b-D-glucuronic acid. This product has a purity of &gt;98% and is soluble in water. It can be used as an intermediate for the synthesis of polysaccharides or saccharides with different substitutions. Adenosine-5'-b-D-glucuronic acid has a CAS number of 73088-94-3 and can be found in the Monosaccharide, Methylation, Glycosylation, Polysaccharide, sugar category.</p>

<p>Lactobionic acid ethyl ester is a custom synthesis of an oligosaccharide that is modified by fluorination, methylation, and click modification. Lactobionic acid ethyl ester is synthesized from the sugar D-glucose and the monosaccharide D-galactose. This product can be used as a substitute for sucrose in food products as it has similar taste, texture and sweetness. It also has many other applications such as being used in the manufacture of polysaccharides and complex carbohydrates.</p>