Sterols

<p>Polyphyllin B (Formosanin C) is a natural saponin compound, which is derived from the rhizomes of plants in the genus Paris, particularly Paris polyphylla. Known for its biological activity, Polyphyllin B functions primarily by disrupting cellular membranes and inducing apoptosis in cancer cells through various signaling pathways, including the mitochondrial pathway. This mechanism is attributed to its ability to interfere with cancer cell proliferation and promote cell death, making it a compound of interest in oncological research.</p>

<p>Betamethasone is a potent anti-inflammatory agent that belongs to the group of corticosteroids. It is used in the treatment of a number of inflammatory diseases, such as allergic states, dermatologic disorders and gastrointestinal disorders. This drug binds to glucocorticoid receptors inhibiting inflammatory signals whilst promoting anti-inflammatory signals.</p>

<p>Segesterone is a synthetic progestin, which is a chemically engineered hormone analogue. It is synthesized from steroid precursors, specifically designed to mimic the naturally occurring hormone progesterone. Segesterone acts primarily through binding to progesterone receptors, exerting its effects by modulating gene expression related to reproductive processes. This mechanism inhibits ovulation, alters cervical mucus to prevent sperm penetration, and modifies the endometrial lining to reduce the likelihood of implantation.</p>

<p>Androsta-1,4,6-triene-3,17-dione is a steroidal aromatase inhibitor, which is a synthetic compound derived from modifications of naturally occurring steroid structures. Its mode of action involves the inhibition of the aromatase enzyme. Aromatase catalyzes the conversion of androgens into estrogens, a critical step in the biosynthesis of estrogens. By inhibiting this enzyme, Androsta-1,4,6-triene-3,17-dione effectively reduces estrogen levels, which can be of particular interest in research environments exploring the role of estrogens in various biological processes.</p>

<p>Epibrassinolide is a plant growth regulator, which is a synthetic analog of brassinosteroids derived from natural plant steroids. It exerts its effects through modulating gene expression and activating signaling pathways that enhance cell elongation, division, and differentiation. Additionally, Epibrassinolide plays a crucial role in improving a plant's tolerance to environmental stresses such as drought, salinity, and temperature extremes. It is widely used in agricultural research and practices to boost crop yield and quality. Researchers apply Epibrassinolide to study its potential in promoting growth, increasing resistance to pathogens, and enhancing overall plant vitality. Its applications extend to various plant species, where it is utilized to explore genetic expressions and physiological adaptations in response to its regulatory effects.</p>

<p>Please enquire for more information about Teasterone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Polyphyllin D is a natural compound, which is a steroidal saponin extracted from the rhizome of Paris polyphylla, a traditional Chinese medicinal plant. It exhibits significant biological activities and has garnered interest for its potential therapeutic applications. Polyphyllin D exerts its effects primarily through the disruption of cellular processes, including the induction of apoptosis, modulation of the cell cycle, and inhibition of angiogenesis. It achieves these actions by influencing multiple molecular pathways, such as the mitochondrial apoptotic pathway and autophagy regulation.</p>

<p>Dioscin is a steroidal saponin, which is a naturally occurring compound found in various plants, notably in species such as Dioscorea nipponica and Dioscorea zingiberensis. These plants belong to the yam family, which are well-regarded for their medicinal properties. The mode of action of dioscin involves modulation of various biochemical pathways, including the suppression of inflammatory cytokines and inhibition of cancer cell proliferation. Additionally, dioscin has been shown to promote apoptosis in cancer cells through the activation of caspases and disruption of mitochondrial function.</p>

<p>Cholesterol is a complex lipid molecule, which is an essential component of cell membranes in animals. It is primarily synthesized in the liver, though it can also be obtained from dietary sources such as meat, dairy, and eggs. Cholesterol's mode of action involves its incorporation into the phospholipid bilayer of cell membranes, where it modulates fluidity and structural integrity, impacting membrane protein function and cellular signaling pathways.</p>

<p>Coumestrol-9-methyl ether is a synthetic estrogen analogue, which is derived from coumestrol, a naturally occurring phytoestrogen found in various plant sources such as soybeans and clover. This compound is synthesized through chemical modification to enhance its stability and bioactivity, differing from its naturally occurring counterpart by the addition of a methyl group.</p>

<p>Bufalin is a bufadienolide compound, which is a type of steroid derived primarily from toad venom, specifically from the skin and parotid venom glands of the toad species Bufo gargarizans. Its mode of action involves the inhibition of Na+/K+-ATPase, an enzyme critical for maintaining the electrochemical gradient across cell membranes. By disrupting this gradient, Bufalin affects cellular ion homeostasis and induces apoptosis in various cancer cell lines.</p>

<p>Equilenin is a steroidal estrogen, which is a type of naturally occurring hormone. It is derived primarily from the urine of pregnant mares and belongs to the class of conjugated equine estrogens. In terms of its mode of action, equilenin functions by binding to estrogen receptors in various tissues, thereby modulating gene expression and influencing cellular activity. This interaction supports the management of estrogen deficiencies in postmenopausal women and can influence the regulation of certain metabolic processes.</p>

<p>Protodioscin is a steroidal saponin, which is a naturally occurring glycoside. It is predominantly sourced from the plant Tribulus terrestris but can also be found in other medicinal plants such as Dioscorea species. The mode of action of protodioscin involves its ability to influence the levels of dehydroepiandrosterone (DHEA) and other hormones, potentially affecting physiological functions related to vitality and performance.</p>

<p>Saponins are naturally occurring glycosides, which are compounds sourced primarily from various plant species, including legumes, herbs, and certain vegetables. These compounds are characterized by their unique structure, comprising a hydrophobic aglycone linked to hydrophilic sugar moieties. This dual nature endows saponins with surfactant-like properties, allowing them to interact with both hydrophilic and hydrophobic molecules.</p>

<p>Composed of Lanosterol (~65%), dihydrolanosterol, agnosterol,dihydroagnosterol.Extracted from wool.</p>

<p>Coumestrol is a phytoestrogen compound, which is a naturally occurring compound found in a variety of plants, such as soybeans, clover, and alfalfa. It is derived from the metabolic processes within these plants. Coumestrol exhibits estrogenic activity, acting as an agonist for estrogen receptors. This biological activity enables coumestrol to mimic the action of endogenous estrogens, thereby influencing estrogen-responsive pathways.</p>

<p>Phytoestrogen with anti-cancer properties</p>

<p>Gracillin is a steroidal saponin, which is a bioactive compound derived from the plant genus Dioscorea. This natural product is characterized by its complex glycoside structure, where a sugar moiety is attached to a steroid-like aglycone. The mode of action of Gracillin involves its interaction with cellular membranes, leading to increased cell membrane permeability. This action is thought to disrupt normal cellular functions, making it a compound of interest for studying membrane dynamics.</p>

<p>Please enquire for more information about Erizimoside including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pabulenol is an innovative biopolymer, which is synthesized from renewable plant-based resources through advanced biotechnological methods involving enzymatic polymerization. With its unique molecular structure, Pabulenol exhibits specific mode of action by facilitating biodegradation under ambient conditions, catalyzed by naturally occurring microbes. The polymer’s intrinsic ability to break down into non-toxic byproducts makes it an exceptional choice for sustainable environmental applications.</p>

<p>7-Dehydrostigmasterol is a phytosterol, which is a type of steroid alcohol derived from plant sources, particularly within the metabolic pathway of various sterols. This compound acts as an intermediate in the biosynthesis of other phytosterols, functioning within key enzymatic conversion processes that are part of the larger sterol metabolic network.</p>

<p>Pseudoprotodioscin is a bioactive saponin compound, which is primarily derived from various plant sources, including members of the genus Tribulus. The compound is part of a larger family of steroidal saponins known for their diverse biological activities. Its mode of action includes influencing cellular pathways through modulation of enzyme activity and interaction with steroid hormone receptors, contributing to its bioactivity.</p>

<p>Betamethasone enol aldehyde Z isomer is a synthetic corticosteroid, which is derived from modifications of the naturally occurring glucocorticoid, cortisol. Its structure has been altered to enhance anti-inflammatory and immunosuppressive potency. As a Z isomer, it exhibits specific stereochemistry, potentially affecting its pharmacokinetics and interactions at the molecular level.</p>

<p>Estradiol is a synthetic or naturally occurring form of estrogen, predominantly sourced from ovarian secretions in females. It performs its mode of action by binding to estrogen receptors, ERα and ERβ, subsequently regulating gene expression and modulating various biological processes including reproductive system development, bone density maintenance, and cardiovascular function.</p>

<p>Betamethasone is a synthetic corticosteroid, which is an analogue of a glucocorticoid sourced from adrenal cortex hormones. Its mode of action involves modulating the immune response by inhibiting the release of substances in the body that cause inflammation. This is achieved through its binding affinity to glucocorticoid receptors, leading to transcriptional changes that suppress pro-inflammatory cytokine production and other mediators of inflammation.</p>

<p>Cholesterol 3-sulfate sodium salt is a fine chemical that is used as a versatile building block and reagent. It is a useful intermediate that can be used in the synthesis of complex compounds, speciality chemicals, and reaction components. Cholesterol 3-sulfate sodium salt can be used to synthesize cholesterol derivatives. This compound has been shown to have high reactivity with nucleophiles and can be used as a building block for other organic compounds. The CAS number for Cholesterol 3-sulfate sodium salt is 2864-50-8.</p>

<p>Lanosterol - 90% is a sterol compound, which is a biochemical precursor to steroids. It is derived from various animal and plant sources, typically synthesized through the enzymatic conversion of squalene. Lanosterol functions through a significant role in the biosynthetic pathway of cholesterol and other essential sterols. This involves the cyclization process, where lanosterol is metabolized into cholesterol through a series of reactions catalyzed by specific enzymes.</p>

<p>Plant hormone</p>

<p>8'-Hydroxyformononetin is a phytoestrogen compound, which is derived from plant sources, particularly from legumes, including red clover and soy. As a naturally occurring isoflavone, it falls within the class of flavonoids, a group of polyphenolic compounds with varied biological activities. Its mode of action primarily involves binding to estrogen receptors, where it can mimic or modulate the action of estrogen in the body. This interaction can result in either estrogenic or anti-estrogenic effects, depending on the presence of endogenous estrogen and other factors within the target tissues.</p>

<p>24-epi-Castasterone is a brassinosteroid, which is a class of plant steroids, often extracted from various plant tissues synthesized in small quantities. This compound is primarily derived from plant sources such as seeds, pollen, and young vegetative tissues. It functions by binding to specific receptor kinases on plant cell membranes, thereby initiating a cascade of intracellular signaling that regulates gene expression. These pathways are crucial for the modulation of plant growth and development processes.</p>

<p>Deoxy miroestrol is a phytoestrogen compound, which is primarily sourced from the root of the Pueraria mirifica plant, indigenous to Thailand. Its mode of action involves mimicking the biological activity of estrogen by binding to estrogen receptors in the body. This estrogenic activity is due to its structural similarity to estrogens naturally produced in the body, allowing it to interact with estrogen receptors and modulate their activity.</p>

<p>Please enquire for more information about Ganoderenic acid B including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Dehydroepiandrosterone is a steroid hormone and a metabolic intermediate in the biosynthesis of androgen and estrogen sex steroids, which is derived from cholesterol in the adrenal glands, gonads, and brain. Acting primarily as a prohormone, it facilitates the synthesis of active steroid hormones by serving as a precursor molecule that undergoes enzymatic conversion into potent androgens like testosterone and dihydrotestosterone, as well as estrogens such as estradiol within peripheral tissues.</p>

<p>Dioscin is a type of steroidal saponin, which is a naturally occurring glycoside. It is primarily derived from various plant sources, including members of the Dioscorea family, such as wild yam species. Dioscin exhibits its biological activity through modulation of multiple molecular pathways, notably exhibiting anti-inflammatory, antioxidative, and antiproliferative effects.</p>

<p>Betamethasone valerate EP Impurity D is a synthetic steroid compound, specifically an impurity of betamethasone valerate. This impurity is typically derived from the chemical synthesis processes associated with the production of betamethasone valerate. It serves as a reference standard in the analytical and pharmaceutical research fields.</p>

<p>Estetrol (E4) is a naturally occurring estrogen, which is synthesized by the human fetal liver. It acts as a selective estrogen receptor modulator with a unique mode of action differentially impacting various tissues. Estetrol selectively binds to estrogen receptors, thereby facilitating a range of estrogenic activities. Interestingly, it exhibits modest estrogenic effects on both the endometrium and breast tissue, reducing potential risks typically associated with hormone therapies.</p>

<p>Ophiopogonin B is a steroidal saponin compound, which is primarily derived from the root tubers of the plant Ophiopogon japonicus. This plant source, commonly used in traditional Chinese medicine, contributes to the compound's extraction. Ophiopogonin B exhibits a multifaceted mode of action, primarily recognized for its biological activities, including antioxidant, anti-inflammatory, and cardioprotective effects.</p>

<p>Testosterone-impurity K is a chemical compound that belongs to the category of impurities identified during the synthesis and formulation of testosterone-related pharmaceuticals. It is typically sourced from the by-products of testosterone synthesis and is crucial for ensuring the purity and efficacy of the final testosterone product. The mode of action of Testosterone-impurity K primarily involves serving as a reference standard or analytical benchmark to identify and quantify impurities present in testosterone preparations.</p>

<p>Marinobufagenin is a bufadienolide compound, which is isolated from the skin and parotid glands of toads, primarily those belonging to the Bufo genus. This compound is characterized by its ability to inhibit Na⁺/K⁺-ATPase, an enzyme crucial for maintaining the electrochemical gradients of sodium and potassium ions across the cell membrane. By inhibiting this enzyme, Marinobufagenin disrupts ion homeostasis, which can lead to increased intracellular calcium concentrations in cardiac muscle cells. This action enhances the force of cardiac contraction, conferring potent cardiotonic effects.</p>

<p>Formononetin-7-acetate is a naturally-derived isoflavonoid, which is a product of acetylation of formononetin, predominantly sourced from red clover and other leguminous plants. Its mode of action involves mimicking the effects of estrogens by binding to estrogen receptors, though with less potency than endogenous estrogens. This interaction may lead to modulation of various estrogen-mediated physiological processes.</p>

<p>Otophylloside B is a naturally occurring triterpenoid saponin, which is a secondary metabolite derived from the roots of the plant **Ophiorrhiza pumila**. This compound is characterized by its complex glycosidic structure, featuring a unique arrangement of sugar moieties attached to its aglycone core. The mode of action of Otophylloside B involves modulation of cellular pathways, particularly influencing apoptosis and cell cycle regulation. Its structure allows interaction with specific cellular receptors, leading to potential inhibition of tumor growth and metastasis.</p>

<p>Pregna-4,8-diene-3,20-dione is a synthetic corticosteroid, which is an analog of naturally occurring hormones produced by the adrenal cortex. This compound is synthesized through complex chemical pathways utilizing steroidal intermediates to produce a substance with potent biological activity. The mode of action of Pregna-4,8-diene-3,20-dione involves its ability to alter the transcription of certain genes by binding to glucocorticoid receptors. This interaction induces the synthesis of proteins that inhibit the inflammatory response and suppress the immune system.</p>

<p>3,9-Di-O-methylcoumestrol is a synthetic coumestan derivative, which is primarily derived or synthesized from various plant sources that produce isoflavonoids and related compounds. As a type of phytoestrogen, it exhibits selective estrogen receptor modulating activity, interacting with estrogen receptors in a manner similar to endogenous hormones but with distinctive affinity and specificity. This mode of action suggests it could influence estrogen-responsive pathways, making it of particular interest in fields like endocrinology and pharmacology.</p>

<p>gamma-Bufotalin is a bufadienolide compound, which is a type of steroid. It is sourced from toad venom, specifically from the parotoid glands of toads belonging to the Bufonidae family. This compound exhibits its mode of action primarily through inhibition of cellular ion pumps, particularly the Na⁺/K⁺-ATPase, leading to an increase in intracellular calcium levels. This mechanism induces apoptosis in certain cancer cell lines, providing a potential pathway for therapeutic intervention.</p>

<p>Ophiopogonin D is a steroidal glycoside, which is a secondary metabolite sourced from the plant Ophiopogon japonicus. This compound is characterized by its presence in the roots, commonly referred to as radix Ophiopogonis, and is part of the broader group of ophiopogonins. Its mode of action primarily involves exerting anti-inflammatory and antioxidant effects. Ophiopogonin D has been shown to modulate signaling pathways that influence cellular oxidative stress and inflammatory responses, which are key in various pathological conditions.</p>

<p>Asparanin B is a natural compound, which is a specialized saponin derived from the roots of asparagus plants, specifically from Asparagus officinalis. It exerts its effects through the modulation of cellular pathways, including the inhibition of cell proliferation, induction of apoptosis, and disruption of key signaling mechanisms involved in cancer development and progression. As a result, Asparanin B is being studied for its potential anticancer properties.</p>

<p>Estradiol 17-propionate is a synthetic estrogenic compound, which is derived from the natural estrogen hormone, estradiol. It is produced through chemical modification to enhance its stability and efficacy, allowing it to be studied as a model of estrogenic action in scientific research. The compound exerts its effects by interacting with estrogen receptors, initiating a cascade of transcriptional events that influence gene expression and cellular function.</p>

<p>Used to produce peptide modified lipid nanoparticles.</p>

<p>Pregnanediol 3α-O-β-D-glucuronide is a steroid conjugate, which is primarily a urinary metabolite derived from the catabolism of progesterone. It represents an important biomarker in endocrinological studies with direct relevance to reproductive biology. The compound originates in the body during the breakdown of progesterone, where it is conjugated with glucuronic acid to increase its solubility for renal excretion. This transformation allows for convenient and non-invasive monitoring of progesterone levels in clinical and research settings.</p>

<p>Halcinonide is a potent topical corticosteroid, which is a synthetically derived compound from hydrocortisone. It operates by penetrating the cell membranes and binding to cytoplasmic receptors, leading to a subsequent translocation to the nucleus where it modulates genetic expression. This action results in diminished synthesis of pro-inflammatory cytokines, thereby exerting strong anti-inflammatory, antipruritic, and vasoconstrictive effects.</p>