Terpenoids

Curcumol is a bioactive compound, which is a sesquiterpenoid alcohol primarily extracted from the rhizome of the plant Curcuma wenyujin, a member of the Zingiberaceae family. The source plant is native to parts of Asia and has been traditionally used in herbal medicine. The mode of action of Curcumol involves modulation of multiple biochemical pathways, including anti-inflammatory and antioxidant pathways. It has been observed to influence cellular signaling cascades that regulate apoptosis, cell proliferation, and angiogenesis, making it a compound of interest in oncology research.

Peduncloside II is a rare glucoside, a type of chemical compound, that is naturally derived from specific plant sources. The source of Peduncloside II is primarily the traditional medicinal plant, which has been utilized in various indigenous pharmacopeias, particularly in certain regions of Asia. It is isolated from plant tissues where it functions as a secondary metabolite.

Ginsenoside F11 is a saponin compound, which is a bioactive component derived from Panax quinquefolius, commonly known as American ginseng. This compound is extracted from the roots of the plant, where it naturally occurs as part of its complex phytochemical profile. Ginsenoside F11 acts through multiple biochemical pathways, primarily by modulating neurotransmitter systems and exhibiting antioxidant properties. It influences cellular mechanisms by interacting with specific receptors and enzymes, thereby affecting signal transduction processes.

Ginsenoside Rc is a bioactive compound, which is a triterpenoid saponin derived from the root of the Panax ginseng plant. It possesses a unique mode of action through its interaction with cell membrane receptors, influencing various signaling pathways. Among its many effects, Ginsenoside Rc modulates immune response, exhibits antioxidant properties, and can regulate glucose metabolism and cardiovascular function.

Ginkgolide M is a diterpenoid trilactone, which is a natural compound derived from the leaves of the Ginkgo biloba tree. Ginkgo biloba is an ancient plant species known for its resilient nature and traditional medicinal use. The mode of action of Ginkgolide M involves antagonism of platelet-activating factor (PAF) receptors. By this mechanism, it influences various biological processes such as platelet aggregation and inflammation, which are critical pathways in numerous physiological and pathological states.

Applications (R)-(-)-Carvone, is an antinociceptive monoterpene found as the main active constituent of essential oils obtained from plants of the genus Mentha. It is a novel agonist of TRPV1 channels. It can also be used as a chiral starting material.
References Goncalves, J.C., et al.: Cytometry part A., 83(2), 212 (2013); Liebigs ann., Chem., 403 (1993);

Linalool - synthetic grade is a versatile terpene alcohol, which is synthetically produced from petrochemicals. Its mode of action involves interacting with olfactory receptors, which contributes to its characteristic floral aroma. Additionally, linalool is involved in various biochemical transformations, often acting as an intermediate in chemical reactions due to its reactive functional groups.

3-Acetyl-beta-boswellic acid is a pentacyclic triterpenoid compound, which is derived from the resin of the Boswellia serrata tree. It exhibits significant biological activity, mainly due to its anti-inflammatory properties. The mode of action primarily involves the inhibition of 5-lipoxygenase, an enzyme crucial in the biosynthesis of leukotrienes, which are mediators in inflammatory and allergic responses. Additionally, it has been shown to modulate various signaling pathways and transcription factors involved in inflammation.

Applications Benzoylpaeoniflorin is a derivative of Paeoniflorin (P133830), a monoterpene glycoside with potential anti-inflammatory activity. Paeoniflorin inhibits monocyte phagocytosis, or the TNF-α and PGE-2 production of monocytes.
References Zhu, X. et al.: Nat. Prod. Res., 28, 301(2014); Di, W. et al.: Int. Immunopharmacol.,, 14, 172 (2012);

Isoalloalantolactone is a sesquiterpene lactone, which is a type of naturally occurring organic compound. It is derived from the roots of Inula helenium, commonly known as elecampane. This plant source is known for its historical use in traditional medicine, often utilized for its purported health benefits.

Lucidenic acid P is a triterpenoid compound, which is a bioactive metabolite isolated from Ganoderma lucidum, a medicinal mushroom known for its diverse pharmacological properties. It is primarily sourced from the fruiting bodies of this fungus, where it is present as part of a complex mixture of triterpenoids.