
Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3567 products of "Nucleosides"
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3-N-Boc-5'-O-DMT-3'-fluorothymidine
CAS:<p>3-N-Boc-5'-O-DMT-3'-fluorothymidine is a monophosphate nucleoside with antiviral and anticancer activity. It is a novel synthetic analogue of fluoro thymidine (FT) that has been shown to be an activator of DNA polymerase α, RNA polymerase β and γ, and protein kinase C. This compound is also an inhibitor of the reverse transcriptase enzyme HIV-1. 3-N-Boc-5'-O-DMT-3'-fluorothymidine has been shown to inhibit cancer cell growth in vitro and in vivo. The synthesis of this compound can be achieved by phosphoramidite chemistry using a commercially available automated synthesizer.</p>Purity:Min. 95%2'-O-Me-5'-O-DMT-1,3-di-N-POM-pseudouridine-3'-CE phosphoramidite
<p>2'-O-Me-5'-O-DMT-1,3-di-N-POM-pseudouridine-3'-CE phosphoramidite is an antiviral agent that inhibits the synthesis of RNA. It has been shown to inhibit the production of new viruses in cultured cells and to be active against some strains of influenza virus. The modification was developed by chemists at Boehringer Ingelheim, who have also synthesised other novel nucleosides that are being tested as anticancer agents. This product is a monophosphate derivative with a high purity level and a CAS number.</p>Purity:Min. 95%2,4-Dithiothymidine
CAS:<p>2,4-Dithiothymidine (DT) is a chemotherapeutic that has been shown to be clinically effective in the treatment of hematopoietic malignancies. It is an oligothymidylate analogue that contains a pyrimidine heterocycle and an ethylthio group. DT is not a nucleoside analog, but it inhibits DNA synthesis by binding to the enzyme thymidylate synthase and preventing the formation of thymine from uracil. DT also binds to single-stranded DNA with high affinity and alters its conformation, which may inhibit transcription and replication. The photophysical properties of this molecule are studied theoretically using quantum mechanics and population analysis theory. The reagent DT can be used to focus attention on other molecules or conformation states of proteins that might have improved biological activity.</p>Formula:C10H14N2O3S2Purity:Min. 95%Molecular weight:274.36 g/molGuanosine-5'-[(b,γ)-methyleno]triphosphate sodium salt
CAS:<p>Guanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt (GMPP) is an analog of guanosine triphosphate that is enzymatically inactivated by the enzyme kinesin. GMPP inhibits the polymerization of microtubules by binding to the kinesin molecule and preventing it from binding to tubulin. GMPP has been shown to inhibit sephadex g-100 chromatography and act as a competitive inhibitor for protein synthesis in vitro. GMPP has also been shown to have a fat cell differentiation effect which may be due to its ability to inhibit microtubule polymerization.</p>Formula:C11H18N5O13P3·xNaPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:521.21 g/mol2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite
<p>2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is a novel nucleoside analog that has been synthesized to have the same chemistry as 2,3'-dideoxycytidine 5'-C phosphoramidite. It has antiviral and anticancer properties. This compound can be used in the synthesis of oligonucleotides for DNA sequencing and for gene therapy.<br>2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is not toxic to normal cells, but it inhibits replication of viruses such as HIV and herpes simplex virus.</p>Formula:C25H32N5O5PPurity:Min. 95%Molecular weight:513.54 g/mol5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine
CAS:<p>5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine is an antiviral drug that inhibits the synthesis of viral DNA. It is synthesized by reacting 5'-deoxyadenosine monophosphate with 2'-O-(2-methoxyethyl)iodoacetamide and methylating the resulting product with methyl iodide. 5'-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine has a novel structure and can be used as an activator of ribonucleosides in DNA synthesis. The drug also has anticancer properties, which may be due to its ability to inhibit cellular proliferation by inhibiting the enzyme DNA polymerase or by arresting cells at the G1 phase of the cell cycle.</p>Purity:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS:<p>N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine is a cytosine analog with high affinity for the T cell receptor. It can be used to generate antibodies against cytosine and as a screening tool for plasmon resonance.</p>Formula:C32H32FN3O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:589.61 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine
CAS:<p>4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine is a novel nucleoside analog with antiviral and anticancer activities. It is a chemical compound with the molecular formula C8H14N6O5P and a molecular weight of 288.28 g/mol. 4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine has the CAS number 136045902, which can be found in PubChem Compound Database.</p>Purity:Min. 95%1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine
<p>1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine is a deoxyribonucleoside, modified nucleoside that is synthesized by using a novel phosphoramidite chemistry. 1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine is an activator of ribonucleotide reductase and can be used in anticancer and antiviral therapy.</p>Purity:Min. 95%N6-Dimethyl-3’-b-C-methyladenosine
CAS:<p>N6-Dimethyl-3’-b-C-methyladenosine is a novel nucleoside analog that has antiviral and anticancer properties. It is a phosphoramidite, which can be used as an activator for the synthesis of modified oligonucleotides. N6-Dimethyl-3’-b-C-methyladenosine has been shown to activate ribonucleosides and deoxyribonucleosides in vitro. This compound also has anticancer properties, which may be due to its ability to act as an activator in the synthesis of DNA.</p>Purity:Min. 95%3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
<p>3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a synthetic nucleoside that belongs to the group of modified nucleosides. It is a phosphoramidite that has been shown to be an effective antiviral and anticancer agent. 3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine inhibits viral replication by interfering with DNA synthesis and repair, which is necessary for viral reproduction. The compound has also been shown to inhibit tumor cell growth in vitro and induce apoptosis in vivo.</p>Formula:C38H34N8O6Purity:Min. 95%Molecular weight:698.73 g/mol2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate
<p>2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate is an antiviral nucleoside with anticancer properties that is synthesized from 2'-deoxyuridine monophosphate and 5-methyluridine. This novel compound has shown antiviral activity against HIV, herpes simplex virus type 1, and herpes simplex virus type 2. It also inhibits the growth of human breast cancer cells in vitro.</p>Purity:Min. 95%5'-O-p-Anisoyl-D3-thymidine
Controlled Product<p>5'-O-p-Anisoyl-D3-thymidine is a nucleoside analogue that is used in antiviral and anticancer treatments. It is synthesized by the condensation of 3,4-dihydroxyacetophenone with 2,6-diaminopurine followed by phosphorylation of the 5' hydroxyl group. This product has been shown to be an activator of both DNA polymerase and RNA polymerase. In addition, it can inhibit the production of viral proteins such as HIV protease without affecting protein synthesis in mammalian cells. It also inhibits cancer cell growth by stopping DNA replication at the G2 phase.<br>5'-O-p-Anisoyl-D3-thymidine has been shown to be highly purified and can be used for research purposes. This product may have a CAS number but it will not be listed on this website due to company policy.</p>Formula:C18H17N2O7D3Purity:Min. 95%Molecular weight:379.38 g/mol9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl)pyridin-3-yl]purine
CAS:<p>9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl)pyridin-3-yl]purine is a nucleoside analog, a type of drug that is used to treat HIV. It is the monophosphate form of the antiviral drug 3TC. The synthesis of 9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl) pyridin-3-yl]purine starts with the preparation of phosphoramidites from 2,4,5,6,-tetraacetyl pyrimidine and 6-(4-methylpiperazinyl)pyridine. The modified nucleosides are then assembled on a DNA template using an automated DNA synthesizer to produce 9-(3'-deoxy-3'-fluoro</p>Purity:Min. 95%N4-Acetyl-5'-O-DMT-cytidine
CAS:<p>N4-Acetyl-5'-O-DMT-cytidine is an antiviral drug that inhibits the viral DNA polymerase. It is a modified nucleoside, which is activated by phosphorylation. N4-Acetyl-5'-O-DMT-cytidine is used in research for its anticancer properties and has shown to inhibit the growth of cancer cells in vitro. The compound was found to be more potent than cytidine and other modified nucleosides.</p>Formula:C32H33N3O8Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:587.63 g/mol3’-Azido-3’-deoxy-N6-dimethyladenosine
CAS:<p>3’-Azido-3’-deoxy-N6-dimethyladenosine (3’ADMA) is a modified nucleoside that can be used as an antiviral and anticancer agent. 3’ADMA is synthesized by modifying the phosphoramidite building block with 2,6-diaminohexanoic acid. This compound is also capable of inhibiting viral replication and tumor growth by inducing DNA damage in cells. 3’ADMA has shown to have high purity and quality, and it can be used in the synthesis of ribonucleosides or deoxyribonucleosides.</p>Purity:Min. 95%4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
CAS:<p>4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a nucleoside monophosphate that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by inhibiting the activity of enzymes needed for nucleotide synthesis. 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine has shown anticancer properties in vitro against human colon cancer cells. This drug has been shown to inhibit the growth of tumor cells with high expression levels of cyclin D1 and low levels of p27 (a cell cycle regulatory protein).</p>Purity:Min. 95%1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine
<p>1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine is a novel nucleoside with anticancer and antiviral activity. It is an activator of the immune system, which can stimulate the production of natural killer cells and cytotoxic T lymphocytes. It has been shown to be a potent inhibitor of HIV replication in vitro. 1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine was synthesized by phosphoramidite chemistry and it is available at high purity with CAS No.</p>Purity:Min. 95%N2,N2-Dimethylguanosine
CAS:<p>N2,N2-Dimethylguanosine is a purine nucleoside that is found in human serum. It belongs to the group of purines and has been shown to be involved in energy metabolism. N2,N2-Dimethylguanosine has been shown to be present at high levels in patients with autoimmune diseases such as rheumatoid arthritis. The x-ray crystal structures of wild-type strains of Escherichia coli and Streptococcus pneumoniae have been determined, which revealed that this compound interacts with the enzyme activity for primary sclerosing cholangitis. This nucleoside can also be detected by LC-MS/MS methods and multivariate logistic regression analysis.</p>Formula:C12H17N5O5Purity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:311.3 g/mol3'-Amino-N6-benzoyl-2',3'-dideoxy-5'-O-DMT-adenosine
<p>A valuable chemical tool for synthesizing modified oligonucleotides with specific functionalities at the 3' end, primarily used in oligonucleotide synthesis.</p>Formula:C38H36N6O5Purity:Min. 95%Molecular weight:656.73 g/mol2',3'-Dideoxy-5-iodouridine
CAS:<p>2',3'-Dideoxy-5-iodouridine is a synthetic nucleoside analog derived from uridine, one of the natural building blocks of RNA. This molecule has been chemically modified to disrupt the normal processes of DNA and RNA synthesis, making it a candidate for antiviral and anticancer research.</p>Formula:C9H11IN2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:338.1 g/mol2'-O-tert-Butyldimethylsilyl-3'-deoxy-5-methyluridine
CAS:<p>2'-O-tert-Butyldimethylsilyl-3'-deoxy-5-methyluridine (2'-O-TBDMS-5'-dMU) is a synthetic nucleoside that is an antiviral agent. It has been shown to be an activator of DNA polymerase, which may be due to its ability to bind to the enzyme's catalytic site and inhibit the enzyme's activity. 2'-O-TBDMS-5'-dMU also has high purity and can be used in the synthesis of modified nucleosides, phosphoramidites, diphosphates, and ribonucleosides.<br>2'-O-TBDMS-5'-dMU is a white powder with a melting point of about 221°C. It is soluble in water and alcohols and insoluble in acetone or ether.</p>Formula:C16H28N2O5SiPurity:Min. 95%Molecular weight:356.49 g/mol3-Acetylpyridine adenine dinucleotide
CAS:<p>A non-physiological analog of nicotinamide adenine dinucleotide (NAD+) in biochemical research, particularly as a tool to study the mechanisms of NAD+-dependent enzymes.</p>Formula:C22H28N6O14P2Purity:Min. 92 Area-%Color and Shape:White Off-White PowderMolecular weight:662.44 g/molN4-Acetyl-3'-deoxy-3'-C-methylcytidine
<p>N4-Acetyl-3'-deoxy-3'-C-methylcytidine is a novel antiviral drug that is modified from cytidine. It is an activator of the monophosphate pathway of DNA synthesis, which causes the incorporation of N4-acetyl-3'-deoxy-3'-C-methylcytidine into ribonucleosides and deoxyribonucleosides. This compound has been shown to be active against a variety of cancers, including leukemia, colon cancer, breast cancer, and prostate cancer.</p>Formula:C12H17N3O5Purity:Min. 95%Molecular weight:283.28 g/molFluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-tr
<p>Fluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-triphosphate] is a modified nucleoside analog that is used as an antiviral agent against herpesviruses. This compound is phosphorylated by the virus encoded thymidine kinase, which converts it to the monophosphate form. Fluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-triphosphate] inhibits DNA synthesis by inhibiting viral DNA polymerase and has been shown to be active against human papillomavirus type 16 (HPV16) in vitro. It has also been shown to inhibit tumor cell proliferation and induce apoptosis in some types of cancer cells.</p>Purity:Min. 95%1,5-Anhydro-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol
<p>1,5-Anhydro-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol is a novel modified nucleoside that is used as an activator in the synthesis of oligodeoxynucleotides and ribonucleosides. It is also used for the synthesis of phosphoramidites for DNA and RNA molecules. This product is available in high purity and quality.</p>Formula:C18H19N5O4Purity:Min. 95%Molecular weight:369.38 g/mol2-Aminoadenosine
CAS:<p>2-Aminoadenosine is a synthetic nucleoside analog of adenosine in which the purine base is 2,6-diaminopurine, featuring an additional amino group at the C2 position. This modification enhances hydrogen bonding potential and alters base-pairing specificity, allowing it to form three hydrogen bonds with uracil or thymine, in contrast to adenine's two. As a result, 2-aminoadenosine has been studied for its impact on nucleic acid stability, replication fidelity, and enzymatic recognition. It has also shown potential in antiviral and anticancer research due to its ability to disrupt normal RNA and DNA metabolism.</p>Formula:C10H14N6O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:282.26 g/molN6-Carbamoylthreonyladenosine sodium salt
CAS:<p>N6-Carbamoylthreonyladenosine sodium salt is a fatty acid that is found in the bacterial cell wall. It has been shown to be an essential component of the cell wall for Gram-positive and Gram-negative bacteria. N6-Carbamoylthreonyladenosine sodium salt has been used to study the mechanism of protein synthesis in bacteria, especially how enzymes are involved in this process. Chemical biology studies have shown that this molecule can bind to DNA and inhibit bacterial growth. The crystal structure of N6-Carbamoylthreonyladenosine sodium salt has also been determined using x-ray diffraction data. This molecule inhibits the binding of proteins to DNA, which prevents transcription and replication. The reaction mechanism involves hydrogen bonding between the oxygen atoms on N6-Carbamoylthreonyladenosine sodium salt and divalent metal ions such as magnesium or zinc, which are required for protein synthesis.</p>Formula:C15H19N6O8·NaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:434.34 g/mol3'-O-Propargylcytidine
<p>3'-O-Propargylcytidine is a monophosphate nucleoside that belongs to the group of synthetic, novel nucleosides and deoxyribonucleosides. It is a modified form of cytidine with an extra methyl group attached to the 3' position of the ribose sugar. 3'-O-Propargylcytidine has been shown to inhibit cancer cells by binding to DNA and preventing transcription and replication. This compound also inhibits virus replication and has antiviral properties. 3'-O-Propargylcytidine is highly pure and high quality, which makes it a good candidate for use in pharmaceuticals or other applications requiring high purity.</p>Formula:C12H15N3O5Purity:(%) Min. 97%Color and Shape:PowderMolecular weight:281.26 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:<p>N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite that is used in the synthesis of DNA. It has been shown to have antiviral activity against HIV and herpes, as well as anticancer effects. It also has high purity, being a novel synthetic nucleoside with a CAS number. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is synthesized using novel methods. The synthesis process includes activation with diphosphate, DNA, and Novel nucleosides, which are high quality and modified.</p>Formula:C53H66N7O8PSiPurity:Min. 95%Color and Shape:PowderMolecular weight:988.19 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine
<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is an activator of DNA polymerase. It has been shown to be a potent inhibitor of viral replication and an anticancer agent in vitro. The compound has also been shown to inhibit the growth of tumor cells in vivo. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue that has not been previously reported.</p>Purity:Min. 95%5'-O-p-Anisoylthymidine
<p>5'-O-p-Anisoylthymidine is a novel activator and ribonucleoside that has been synthesized by modifying the structure of thymidine. This compound is active against cancer and antiviral, such as herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, influenza A/PR/8/34 (H1N1), and influenza B/Yamagata/16/88. 5'-O-p-Anisoylthymidine activates viral transcription in cells infected with these viruses by inhibiting the synthesis of deoxyribonucleosides. It also inhibits DNA synthesis by inhibiting the incorporation of deoxyribonucleotides into DNA during replication. This product is CAS No. 138581-03-2 and comes in high purity and high quality.</p>Formula:C18H20N2O7Purity:Min. 95%Molecular weight:376.36 g/mol3’-b-C-Methyluridine
CAS:<p>3’-b-C-Methyluridine (3′-b-CMU) is an analog of uridine. It inhibits the activity of viral and bacterial nucleases by attacking the phosphate group. 3′-b-CMU inhibits syncytial formation in cell cultures, which may be due to its ability to inhibit RNA synthesis. This drug has a hydroxyl group that can react with free radicals and may have some inhibitory effect on deoxyribonucleoside triphosphate hydrolysis. 3′-b-CMU is not widely used clinically because it is not readily available, but it is being reinvestigated for use in corynebacterium infections.</p>Purity:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite
CAS:<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite is a synthetic, antiviral monophosphate nucleoside. It is an activator that increases the activity of other nucleosides and can be used in DNA synthesis by incorporation into DNA molecules. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite has been shown to be effective against Hepatitis C virus, Human Immunodeficiency Virus 1 (HIV), and Herpes Simplex Virus 1.</p>Formula:C47H64N7O8PSiPurity:Min. 95%Color and Shape:PowderMolecular weight:914.11 g/mol3'-Deoxythymidine
CAS:<p>3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.</p>Formula:C10H14N2O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:226.23 g/molQueuine hydrochloride
CAS:<p>Queuine is a modified nucleoside found in tRNA. It is synthesized from guanosine by the enzyme queuine tRNA-ribosyltransferase, which converts guanosine to queuosine. Queuine hydrochloride is a synthetic form of queuine that can be used for research purposes to examine the anticodon loop and other structural features of the molecule. The prokaryotic and eukaryotic organisms studied showed different levels of synthesis of queuine, with bacteria synthesizing more than mammals. Bacteria were found to have a greater affinity for queuine than eukaryotes, which may be due to modification of the trna anticodon loop or to differences in ribosomal proteins.</p>Formula:C12H15N5O3·HClPurity:(%) Min. 90%Color and Shape:Light (Or Pale) Beige To Light (Or Pale) Purple SolidMolecular weight:313.74 g/molNicotinic acid riboside
CAS:<p>Nicotinic acid riboside is a nicotinic acid derivative that has been shown to increase NAD+ levels in cells. Nicotinic acid riboside has been shown to increase the activity of enzymes involved in energy metabolism and transfer reactions, as well as target enzymes such as nicotinamide phosphoribosyltransferase (NAMPT) and its substrate, nicotinamide mononucleotide (NMN). It also increases cellular NAD+ levels by inhibiting the degradative enzyme, nicotinamide phosphoribosyltransferase (NAMPT). Nicotinic acid riboside can be used to treat metabolic disorders such as diabetes mellitus type 2.</p>Formula:C11H13NO6Purity:Min. 95%Color and Shape:PowderMolecular weight:255.22 g/mol5'-O-DMT-N4-ethylcytidine
<p>5'-O-DMT-N4-ethylcytidine is a novel nucleoside analogue. It has been used as a building block for the synthesis of modified oligonucleotides. 5'-O-DMT-N4-ethylcytidine is an antiviral agent that inhibits HIV replication by inhibiting reverse transcriptase, which is an enzyme that is necessary for the production of viral DNA from host cell RNA. The drug also has anticancer activity, which may be due to its ability to inhibit DNA synthesis and cellular proliferation.</p>Formula:C32H35N3O7Purity:Min. 95%Molecular weight:573.64 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine
<p>N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine is a modified nucleoside with antiviral activity. This compound is synthesized by a modified method that avoids the use of phosphoramidites, which are usually used to synthesize nucleosides. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine is an activator of viral RNA polymerase and has been shown to be active against HIV and herpes simplex virus type 1.</p>Purity:Min. 95%3',5'-Bis-O-tert-butyldimethylsilyl-2'-deoxy-2',2'-difluorocytidine
CAS:<p>3',5'-Bis-O-tert-butyldimethylsilyl-2'-deoxy-2',2'-difluorocytidine is a modified nucleoside that is used as an antiviral agent. It is a phosphoramidite or monophosphate, which can be synthesized from 2'-deoxycytidine and N,N-bis(tert-butyldimethylsilyl)acetamide. 3',5'-Bis-O-tert-butyldimethylsilyl-2'-deoxy-2',2'-difluorocytidine inhibits the synthesis of DNA and RNA by inhibiting the enzymes DNA gyrase and RNA polymerase II. This drug has been shown to have anticancer effects in vitro and in vivo.</p>Purity:Min. 95%N6,7-Dimethyldeoxyadenosine
<p>N6,7-Dimethyldeoxyadenosine is a nucleoside with antiviral and anticancer properties. It is a modified DNA monophosphate with the chemical formula C8H16N2O6P. N6,7-dimethyldeoxyadenosine has been shown to inhibit the replication of HIV and herpes simplex virus type 1 (HSV-1) in vitro. This compound also inhibits the growth of cancer cells in culture and has been suggested as an anticancer therapeutic agent.</p>Purity:Min. 95%5'-O-tert-Butyldimethylsilyl-2'-deoxyuridine
<p>5'-O-tert-Butyldimethylsilyl-2'-deoxyuridine (5'-O-TBDMSU) is a modified nucleoside that has antiviral, anticancer and novel activities. It is synthesized by the reaction of 5'-O-tert-butyldimethylsilyl-2'-deoxyuridine with methyl chloroformate. 5'-O-TBDMSU has been shown to inhibit viral replication in cell culture. The antiviral activity of 5'-O-TBDMSU may be due to its ability to inhibit DNA synthesis by inhibiting the incorporation of deoxyribonucleotide triphosphates into DNA or by inhibiting the activity of DNA polymerases. This compound also inhibits the replication of RNA viruses such as HIV and hepatitis C virus, which are dependent on deoxyribonucleosides for their replication.</p>Formula:C15H26N2O5SiPurity:Min. 95%Molecular weight:342.47 g/molL-Thymidine
CAS:<p>L-Thymidine is an antiviral drug that is used in the treatment of chronic hepatitis. It has been shown to be active against a range of viruses, including HIV, HSV, and HBV. L-Thymidine can also be used to treat patients with cancer as an anti-cancer agent. L-Thymidine is a prodrug that is converted into thymidine triphosphate (TTP), which inhibits viral DNA polymerase by competitive inhibition. The antiviral activity of L-Thymidine may be due to its ability to inhibit the synthesis of viral proteins required for viral replication by interfering with the protein production process or by inhibiting the formation of dsDNA during reverse transcription.</p>Formula:C10H14N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:242.23 g/mol5'-O-p-Anisoyl-2,2'-anhydrouridine
<p>5'-O-p-Anisoyl-2,2'-anhydrouridine is a novel nucleoside. It is an activator of ribonucleosides and deoxyribonucleosides. This compound has antiviral activity against HIV and DNA synthesis inhibitory activity against cancer cells. 5'-O-p-Anisoyl-2,2'-anhydrouridine is also a modified nucleoside that can be used for the synthesis of phosphoramidites for the chemical synthesis of oligodeoxynucleotides (ODN).</p>Formula:C17H16N2O7Purity:Min. 95%Molecular weight:360.32 g/mol7-Deaza-2'-deoxyadenosine
CAS:<p>7-Deaza-2'-deoxyadenosine is an oligodeoxynucleotide analog that has been shown to be a potent inhibitor of human ovarian carcinoma cells. It inhibits the uptake of organic anion transporters, which are proteins found in the cell membrane that transport organic anions such as nucleosides and nucleotides. 7-Deaza-2'-deoxyadenosine has also been shown to inhibit DNA synthesis and polymerase chain reactions by binding to the enzyme RNA polymerase II. This drug can be synthesized with solid phase chemistry, making it a highly reproducible product.</p>Formula:C11H14N4O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:250.26 g/mol1-Methylpseudouridine
CAS:<p>1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).</p>Formula:C10H14N2O6Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:258.23 g/mol5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine
<p>5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine is a novel nucleoside that is synthesized from ribonucleosides. It is an inhibitor of the RNA polymerase enzyme, which prevents the transcription and replication of DNA. 5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine also inhibits viral DNA synthesis by preventing viral RNA from being translated into DNA. This product has been shown to be active against a wide range of viruses, including influenza A virus, herpes simplex virus type 1, and vaccinia virus.</p>Formula:C16H15FN2O5Purity:Min. 95%Molecular weight:334.35 g/mol8-Azidoadenosine
CAS:<p>8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.</p>Formula:C10H12N8O4Purity:Min. 95%Color and Shape:PowderMolecular weight:308.25 g/mol5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine
CAS:<p>5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine is a nucleoside that has been synthesized using an oxime opening of the 5' position and a methylation at the 2' position. It has been shown to have an affinity for tissues in a chemotactic assay. The compound is minimised to remove non-specific binding sites, avoiding false positives on the checklist. This molecule has been analysed with fluorescence spectroscopy and microscopy techniques, which revealed that it is distributed in tissues as well as being found in dragonflies. It was also shown to be transduced by muscle cells and geochemically detected in limestone from China.</p>Formula:C36H39N5O8Purity:Min. 95%Color and Shape:PowderMolecular weight:669.74 g/molN4,3'-O-Dibenzoyl-2'-deoxycytidine
CAS:<p>N4,3'-O-Dibenzoyl-2'-deoxycytidine is a nucleoside that functions as a base. It is a diester of the naturally occurring nucleoside cytidine and 2′,6′-dibenzoyl-deoxyribose. The compound has been shown to be an inhibitor of DNA polymerases and nuclease activity in vitro. N4,3'-O-Dibenzoyl-2'-deoxycytidine has been shown to inhibit the growth of certain strains of bacteria and can be used for the treatment of tuberculosis. This drug also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. !-- END OF PRODUCT DESCRIPTIONS --></p>Formula:C23H21N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:435.44 g/mol5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:<p>5'-O-DMT-uridine 3'-CE phosphoramidite is a novel, modified and activator nucleoside. It can be used as an antiviral agent or in the synthesis of DNA. 5'-O-DMT-uridine 3'-CE phosphoramidite has been shown to be cytotoxic in vitro to cancer cells.</p>Formula:C39H47N4O9PPurity:Min. 95%Molecular weight:746.79 g/mol5-Hydroxymethyl-2’-O-(2-methoxyethyl)uridine
CAS:<p>5-Hydroxymethyl-2’-O-(2-methoxyethyl)uridine (5HMEU) is a nucleoside that is synthesized from 2’,3’-dideoxyribonucleosides. 5HMEU has been shown to be an activator of the human telomerase enzyme and is used in the synthesis of DNA. It also has anticancer properties and can inhibit the growth of various cancer cells, including pancreatic, breast, prostate, lung, liver, and cervical cancer cells. 5HMEU is a modified nucleoside that contains a hydroxyl group at the 2’ position and an methoxyl group at the 5’ position. The chemical name for 5HMEU is 5-hydroxymethyl-2'-O-(2-methoxyethyl)uridine.</p>Purity:Min. 95%1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine
<p>1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine is a deoxyribonucleoside monophosphate with antiviral effects. It is a novel nucleotide analogue that contains an azido group and a 2,4,6-trifluorobenzene moiety. The 4′ position of the sugar is modified with an n-docosanoyl group. 1-(4’Azo-2′deoxy-2′fluoro-bDara)ribonucleosides are synthetic nucleotides that can be used to inhibit viral replication by inhibiting DNA polymerase and RNA polymerase.</p>Purity:Min. 95%5-Methyl-4’-thiocytidine
CAS:<p>5-Methyl-4’-thiocytidine is an antiviral agent that has been shown to be effective against herpes simplex virus (HSV) type 1 and 2. 5-Methyl-4’-thiocytidine inhibits viral replication by competing with deoxyribonucleosides for incorporation into the viral DNA, which leads to the synthesis of defective DNA. This drug also has anticancer properties and is used in the treatment of leukemia, lymphoma, and carcinomas. 5-Methyl-4’-thiocytidine is a novel monophosphate nucleoside that can be used as an activator for phosphoramidite synthesis. The CAS number for this compound is 1312295-87-6. Synthesis of 5-methyl 4’ thiocytidine requires high purity, high quality nucleosides, and a novel phosphoramidite synthesis procedure.</p>Purity:Min. 95%N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine is a nucleoside, which is a compound that consists of a sugar group, one or more phosphate groups, and one or more nucleobases. It is an analogue of cytidine with modifications in the sugar portion and the substitution of 2'-fluoro-5-methyluracil for uracil. This compound has been shown to be effective against cancer cells when used in combination with other anticancer agents. It also inhibits viral replication by acting as a competitive inhibitor of reverse transcriptase, preventing RNA synthesis. This compound also exhibits antiviral activity by inhibiting the synthesis of viral DNA and RNA.</p>Formula:C38H36FN3O7Purity:Min. 95%Molecular weight:665.72 g/mol2'-O-Benzoyl-5'-O-DMT-4-thiouridine
<p>2'-O-Benzoyl-5'-O-DMT-4-thiouridine is a phosphoramidite monophosphate nucleoside analog. It has antiviral and anticancer properties, and has been shown to activate the immune system in mice. 2'-O-Benzoyl-5'-O-DMT-4-thiouridine is also novel because it is structurally different from all other nucleosides that have been studied for antiviral and anticancer activity. This drug can be used as an activator of DNA synthesis in vitro.</p>Formula:C37H34N2O8SPurity:Min. 95%Color and Shape:Yellow SolidMolecular weight:666.76 g/mol2-Azidoadenosine
CAS:<p>2-Azidoadenosine is a nucleoside analog of adenosine, where the 2'-hydroxyl group of the ribose sugar is replaced with an azido group (–N₃). This substitution imparts unique chemical properties, notably enabling molecules to undergo bioorthogonal reactions, such as click chemistry, which involves the cycloaddition of the azide group with alkynes.</p>Formula:C10H12H8O4Purity:Min. 95%Color and Shape:PowderMolecular weight:308.25 g/mol6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:<p>6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.</p>Formula:C10H12N4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:268.29 g/molN4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine
CAS:<p>N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a synthetic nucleoside that is used as an activator for DNA synthesis. It is also used in the preparation of diphosphate derivatives for use as antiviral and anticancer agents or as probes for DNA and RNA research. N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a novel, high purity, and high quality chemical with CAS No. 86234-45-9.</p>Formula:C37H35N3O7Purity:Min. 95%Molecular weight:633.69 g/mol2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:<p>2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is a nucleoside that is used in the synthesis of DNA. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is an antiviral, antineoplastic, and anticancer agent. It has been shown to be active against some strains of HIV and herpes viruses. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt also inhibits DNA polymerase and RNA polymerase, preventing viral replication and transcription.<br>The phosphate group on the 5' end of this molecule can be modified to produce phosphoramidites, diphosphates, or triphosphates.</p>Formula:C9H11FN3O13P3·Li4Purity:Min. 95%Molecular weight:508.88 g/mol2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt
CAS:<p>2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt is a nucleoside that can be used as an antiviral or anticancer drug. It is a modified nucleoside, which is synthesized by phosphoramidite chemistry. 2'-O-Methyl-5'-methyluridine 5'-triphosphate triethylammonium salt has been shown to be an activator of DNA polymerase in vitro and in vivo. It also has high purity and high quality.</p>Formula:C11H19N2O15P3Purity:Min. 95%Molecular weight:512.19 g/mol5-Ethynyl-2'-O-methyluridine triphosphate
<p>5-Ethynyl-2'-O-methyluridine triphosphate is a novel nucleoside that contains a methyl group at the 5 position of the uracil ring. It is an antiviral agent for use in the treatment of HIV, herpes simplex virus, cytomegalovirus, and influenza virus infections. 5-Ethynyl-2'-O-methyluridine triphosphate is also used as a precursor to synthesize DNA and RNA. This compound has been shown to have anticancer properties against breast cancer cells.</p>Purity:Min. 95%2,8-Dimethyladenosine
CAS:<p>2,8-Dimethyladenosine is a methylated derivative of the purine nucleoside adenosine, in which methyl groups are added at the 2-position and 8-position of the adenine base.</p>Formula:C12H17N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:295.29 g/molGuanosine 3', 5'- bisdiphosphate lithium salt
CAS:<p>Regulates gene transcription; inhibits the synthesis of tRNA and rRNA</p>Formula:C10H17N5O17P4·xLiPurity:Min. 95%Molecular weight:603.16 g/mol2’-Deoxy-N4-dimethylcytidine
CAS:<p>2’-Deoxy-N4-dimethylcytidine is a synthetic nucleoside analog that is used to inhibit viral replication in the treatment of AIDS and cancer. It is phosphorylated by adenosine kinase to form deoxydimethylcytidine monophosphate (dDMP), which inhibits viral DNA synthesis by inhibiting the activity of reverse transcriptase, an enzyme involved in the production of viral DNA. 2’-Deoxy-N4-dimethylcytidine has also been shown to inhibit cancer cell growth by interrupting mitosis and inducing apoptosis.</p>Purity:Min. 95%5-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:<p>5-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a novel nucleoside and phosphoramidite activator. It is synthesized from 2'-deoxyadenosine, 5'-chloropurine riboside, and 1,1'-bis(diisopropylphosphino)ferrocene. This compound has been shown to be an effective antiviral and anticancer agent in vitro.</p>Formula:C12H15ClN4O4Purity:Min. 95%Molecular weight:314.72 g/molCytidine based prodrug with gemcitabine
<p>Cytidine based prodrug with gemcitabine is a nucleoside analog that has antiviral and anticancer properties. It is a modified cytidine-based prodrug with gemcitabine which is an anticancer drug. Cytidine based prodrug with gemcitabine inhibits viral DNA synthesis by competitively inhibiting the incorporation of deoxycytidine monophosphate into the viral DNA chain. The prodrug also inhibits the proliferation of cancer cells by interfering with DNA synthesis, which leads to cell death.</p>Purity:Min. 95%7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine
CAS:<p>7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine is a novel modified ribonucleoside. It has the ability to activate DNA at the monophosphate level and can be used as a substrate for DNA polymerase and in the synthesis of deoxyribonucleosides. 7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine also has antiviral properties, which may be due to its inhibition of viral RNA synthesis. The compound is also used in anticancer treatment as it inhibits cellular proliferation by inhibiting DNA synthesis.</p>Purity:Min. 95%2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt
<p>2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt is a nucleoside that can be used in the synthesis of DNA and RNA. It is a synthetic, high quality, and novel compound that has been shown to have antiviral, anticancer, and anti-inflammatory properties. This compound has been shown to inhibit the growth of cancer cells by inhibiting the production of proteins vital for cell division. 2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt has also been shown to be an activator of nucleoside phosphorylase and deoxynucleotide kinase, which are enzymes that catalyze the conversion of nucleosides into their corresponding monophosphates.</p>Purity:Min. 95%EdU
CAS:<p>2'-Deoxy-5-ethynyluridine (5-EdU) is a modified thymidine analogue containing a terminal alkyne group, which is used for nucleotide labelling. 5-Edu is easily taken up by cells and incorporated by metabolic activation during DNA synthesis. By adding an azide conjugated to a fluorophore or a biotin moiety, a click reaction occurs from the labelled nucleotide linked by a triazole group. 5-Edu are employed in cell proliferation assays, to study DNA and RNA localisation, structure and dynamics, in the synthesis of aptamers with the click-SELEX method, and in other applications such as the preparation of oligonucleotide microarrays and nanoelectronic devices.</p>Formula:C11H12N2O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:252.23 g/molN6-Cyclopentyl-2'-C-methyl-adenosine
CAS:<p>N6-Cyclopentyl-2'-C-methyl-adenosine is an antiviral agent that inhibits the synthesis of DNA by preventing the formation of RNA from DNA. It has been shown to be effective against HIV and other retroviruses. N6-Cyclopentyl-2'-C-methyl-adenosine is a synthetic nucleoside that is activated by phosphorylation in cells, which leads to the synthesis of monophosphate (5'-AMP). This compound is used for the treatment of cancer and HIV infection.</p>Formula:C16H23N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:349.39 g/molb-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium)
CAS:<p>b-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium), or NADPH, is involved in redox reactions, where it acts as an electron donor. NADPH is essential for anabolic reactions, such as lipid and cholesterol biosynthesis, and fatty acid chain elongation. It also plays a significant role in antioxidation mechanisms, protecting cells from oxidative stress by neutralizing reactive oxygen species (ROS) and regenerating antioxidants like glutathione</p>Formula:C21H30N7O17P3·4C6H13NPurity:Min. 90 Area-%Color and Shape:Slightly Yellow PowderMolecular weight:1,142.12 g/mol1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine
CAS:<p>1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is a synthetic, modified nucleoside that can be phosphorylated to its monophosphate form. It is an inhibitor of DNA synthesis and the replication of viral DNA. 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine has been shown to have anticancer activity in vitro and in vivo. This drug is also active against some RNA viruses such as hepatitis B virus and human immunodeficiency virus type 1 (HIV).</p>Formula:C9H12ClN3O4Purity:Min. 95%Molecular weight:261.66 g/mol3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine
<p>3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that inhibits DNA synthesis by competitively inhibiting the activity of deoxycytidine kinase. 3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine is an antiviral agent and has been shown to be effective against herpes simplex virus type 1 and varicella zoster virus. It has also been shown to have anticancer properties, which may be due to its ability to inhibit the growth of human breast cancer cells in culture.</p>Formula:C24H24N4O6Purity:Min. 95%Molecular weight:464.47 g/mol2',3'-Dideoxy-5-methylcytidine
CAS:<p>2',3'-Dideoxy-5-methylcytidine is a synthetic nucleoside analog based on cytidine, a natural building block of DNA and RNA. This molecule is chemically modified to interfere with nucleic acid synthesis, making it a potential tool in antiviral or anticancer therapy, or for studying epigenetics.</p>Formula:C10H15N3O3Purity:Min. 95%Color and Shape:PowderMolecular weight:225.25 g/molN2,N2,7-Trimethylguanosine
CAS:<p>Trimethylguanosine is a hydrogen-bonded base that is found in the DNA of all living organisms. It has a diagnostic role in cancer and metabolic disorders, as well as in the study of cell culture. Trimethylguanosine can be used to identify cancer cells by measuring its fluorescence properties, which are different from those of healthy cells. This compound also has a role in the diagnosis of metabolic disorders, such as diabetes mellitus and renal disease. Trimethylguanosine is also involved in biological function, and is necessary for the synthesis of proteins and nucleic acids.</p>Formula:C13H20N5O5Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:326.33 g/mol2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine
<p>2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine is a novel modified nucleoside with antiviral and anticancer activities. It is synthesized from 2'-deoxyuridine monophosphate, which is activated with bis(trimethylsilyl)acetamide (BSA). This nucleoside has been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Purity:Min. 95%2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine
CAS:<p>2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine is a modified nucleoside that is used as an anticancer drug. It is synthesized from 2’,3’,5’triphosphate and 2’C-methyl-5-methoxyuridine. This compound is used to treat leukemia and other cancers by inhibiting the synthesis of DNA. Inhibiting DNA synthesis prevents the reproduction of cancer cells. The chemical structure of this compound was first published in 2007.</p>Purity:Min. 95%Clofarabine 5'-triphosphate triethylammonium salt
CAS:<p>Clofarabine is a nucleoside analog that is used to treat various types of cancer, including leukemia, lymphoma, and solid tumours. Clofarabine has been shown to have minimal toxicity in healthy cells and is usually well tolerated by patients. It acts by inhibiting the synthesis of DNA in rapidly dividing cells. This effect can be synergistic with other anti-cancer agents such as the cytotoxic agent Bleomycin. Clofarabine binds to an intracellular target and inhibits DNA synthesis by blocking the enzyme DNA polymerase. Inhibition of this enzyme leads to cell death. Clofarabine has been tested in pediatric patients from age 1 month old up to 18 years old. The drug has been found to be safe for use in this population.</p>Formula:C10H14ClFN5O12P3Purity:Min. 95%Color and Shape:PowderMolecular weight:543.62 g/mol2'-Deoxyuridine-5'-triphosphate trisodium
CAS:<p>2'-Deoxyuridine-5'-triphosphate trisodium salt is a fluorophore that is excited by the absorption of light at wavelengths of 365 nm. The emission spectrum ranges from 380 to 500 nm and has a maximum at 480 nm. 2'-Deoxyuridine-5'-triphosphate trisodium salt can be used as a labeling agent for metal ion, molecule, or macrocyclic ligand. It can also be used as an acceptor in fluorescence energy transfer experiments.</p>Formula:C9H15N2O14P3•Na3Purity:Min. 95%Color and Shape:PowderMolecular weight:537.11 g/mol3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine
CAS:<p>3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine is a modified nucleoside that can be used as an antiviral agent. It is a phosphoramidite that is activated by diphosphate and has been shown to inhibit DNA replication in vitro. 3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine also has anticancer activity and can be used to treat leukemia, lymphoma, and myeloma. This high quality product is synthesized from natural deoxyribonucleosides and has a purity of > 98%.</p>Formula:C16H21N5O6Purity:Min. 95%Molecular weight:379.37 g/molCTP 2Na
CAS:<p>CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.</p>Formula:C9H14N3Na2O14P3Purity:Min. 95.0 Area-%Color and Shape:White PowderMolecular weight:527.12 g/mol1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt
<p>1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is an Activator for the synthesis of DNA and RNA. It is a novel synthetic nucleoside that has anticancer activity. 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is used as an antiviral agent, inhibiting viral replication by blocking the RNA polymerase enzyme.</p>Formula:C9H13FN2O14P3·C6H16NPurity:Min. 95%Molecular weight:587.32 g/mol1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol
<p>1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is a novel, activator ribonucleosides deoxyribonucleosides diphosphate phosphoramidites modified anticancer antiviral monophosphate nucleosides synthetic high purity CAS No. It has been shown to have anticancer and antiviral properties. This compound also inhibits the replication of HIV in vitro.</p>Formula:C15H21N5O5Purity:Min. 95%Molecular weight:351.37 g/molN6-Benzoyl-2',3'-isopropylideneadenosine
CAS:<p>N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.</p>Formula:C20H21N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:411.41 g/mol5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)uridine
CAS:<p>5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)uridine is a synthetic nucleoside that has antiviral and anticancer properties. This compound is an activator of DNA, which promotes the synthesis of RNA and protein. 5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)uridine (IDOX) is an analog of deoxyribonucleosides, ribonucleosides, and monophosphates. IDOX is able to inhibit the replication of certain viruses by acting as a competitive inhibitor. This compound also has the ability to inhibit tumor cells that contain pyrimidine analogs. IDOX is also effective against cancer cells that have developed resistance to chemotherapy drugs such as 5FU or methotrexate.</p>Purity:Min. 95%4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine
CAS:<p>4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine is a monophosphate of the nucleoside 5FU. It is an antiviral and anticancer agent that inhibits viral DNA synthesis by competitively inhibiting the activity of thymidylate synthase, which converts dUMP to dTMP. 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine also induces apoptosis in neoplastic cells. This compound has high purity and quality, and can be used as a phosphoramidite for the synthesis of modified oligonucleotides.</p>Formula:C10H10FNO4Purity:Min. 95%Molecular weight:227.19 g/molN6-Benzoyl-2'-C-methyladenosine
<p>N6-Benzoyl-2'-C-methyladenosine is synthetic and has antiviral properties. It is a nucleoside that belongs to the group of modified nucleosides. This compound can be used as an activator for DNA synthesis and as a novel monophosphate, diphosphate, or triphosphate. N6-Benzoyl-2'-C-methyladenosine is also available in high purity, with CAS No., and at a competitive price.</p>Purity:Min. 95%9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine
<p>9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine is an oligonucleotide with a fluorinated nucleobase that is used to stabilize DNA duplexes. It is synthesized from 5'-deoxy-5'-fluorocytidine, which is a phosphoramidite, and 2',3',5'-triacetylpyrimidine, which is a substituent. The deprotection of the fluorinated oligonucleotide can be achieved by treatment with sodium hydroxide in ethanol or hydrochloric acid in acetic acid. 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine has been shown to be stable and antiparallel when incorporated into double stranded DNA molecules.</p>Formula:C10H12FN5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.24 g/mol5-Methyl-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:<p>5-Methyl-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a synthetic nucleoside analog of 2'-deoxyadenosine. It is an activator of DNA synthesis and replication by virtue of its ability to inhibit the enzyme ribonucleotide reductase. The compound has antiviral and anticancer activities, as well as antitumor activity. 5-Methyl-7-(2-C-methyl-b-Dribofuranosyl)-7H-[1,2] pyrrolo[2,3]-d]pyrimidin--4--amine has shown good results in treating chronic myelogenous leukemia.</p>Formula:C13H18N4O4Purity:Min. 95%Molecular weight:294.31 g/mol1-(b-L-Threonyl)uracil
<p>1-(b-L-Threonyl)uracil is a novel anticancer drug that has been synthesized with the aim of increasing the efficacy of DNA synthesis. The incorporation of this nucleoside in the DNA chain prevents the formation of ribonuclesides, which are inhibitory to DNA synthesis. It also inhibits viral replication and can be used as a treatment for HIV infection. 1-(b-L-Threonyl)uracil is synthesized by reacting b-L-threonyl chloride with uracil in the presence of a base and a catalytic amount of thiourea. This product is used in biotechnology as an activator for phosphoramidites and modified nucleosides.</p>Purity:Min. 95%3’-Azido-3’-deoxy-b-L-adenosine
CAS:<p>3’-Azido-3’-deoxy-b-L-adenosine is a novel nucleoside that has been synthesized to be used as an antiviral agent. It is phosphorylated, which allows it to be activated by adenosine kinase, and is thus able to inhibit viral replication and spread. 3’-Azido-3’-deoxy-b-L-adenosine is effective against various viruses, including HIV, herpes simplex virus type 1 (HSV1), and hepatitis C virus (HCV). This nucleoside also has anticancer activity due to its ability to inhibit the synthesis of DNA and RNA. It has been modified from the natural nucleosides with the addition of a 2′,3′ azido group at the 3 position on the ribose sugar. The modification prevents viral resistance because it does not require activation by cellular kinases or phosphorylation in order to be active.</p>Purity:Min. 95%2'-Deoxyadenosine 3'-O-L-valinyl ester
<p>2'-Deoxyadenosine 3'-O-L-valinyl ester is a novel nucleoside phosphoramidite that is synthesized by activating the 2'-deoxyribose phosphate with an L-valyl chloride. This synthetic nucleoside analog can be used as a substitute for dATP in DNA synthesis and has antiviral as well as anticancer activities.</p>Purity:Min. 95%5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine
CAS:<p>5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine is a monophosphate nucleoside. It is an antiviral and anticancer agent that inhibits viral replication by inhibiting the synthesis of viral DNA. It also has been shown to have antitumor activity, but it can only be used in cancer treatments when combined with other drugs such as 5FU. The chemical formula for 5’-Deoxy-5’-iodo-2’O methyl -5 methyl uridine is C10H14N4O8P.</p>Purity:Min. 95%5'-O-tert-Butyldimethsilyl-2'-Deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite
<p>5'-O-tert-Butyldimethsilyl-2'-Deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel nucleoside analog with antiviral and anticancer properties. It is a modified nucleoside that is synthesized by reacting 5'-O-tert-butyldimethylsilyl guanosine with 2'-deoxyisobutyryl chloride in the presence of triethylamine. The resulting 5'-O-tert-butyldimethylsilyl-2'-deoxyisobutyrylguanosine 3'-CE phosphoramidite has been shown to be cytotoxic to tumor cells without affecting normal cells.</p>Formula:C29H50N7O6PSiPurity:Min. 95%Molecular weight:651.82 g/mol8-Azido-2'-deoxyadenosine
CAS:<p>8-azido-2-deoxyadenosine is an azide funcationalised nuceleoside</p>Formula:C10H12N8O3Purity:Min. 95%Color and Shape:PowderMolecular weight:292.25 g/mol1-(2'-Deoxy-2'-fluoro-5-methyl-b-D-arabinofuranosyl)cytosine 5'-triphosphate triethylammonium salt
<p>1-(2'-Deoxy-2'-fluoro-5-methyl-β-D-arabinofuranosyl)cytosine 5'-triphosphate triethylammonium salt is an antiviral nucleoside that can inhibit the replication of DNA and RNA viruses. It is a novel, synthetic nucleoside that has not been previously reported in the literature. This compound has been shown to be active against some human cancer cells in vitro, but no studies have been conducted in vivo. 1-(2'-Deoxy-2'-fluoro-5-methyl-β-D-arabinofuranosyl)cytosine 5'-triphosphate triethylammonium salt also shows anticancer activity with minimal toxicity to normal cells in vitro.</p>Purity:Min. 95%6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine
CAS:<p>6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine is a modified monophosphate analog of adenosine. It is an antiviral agent that inhibits the synthesis of nucleic acids in virus-infected cells, preventing viral replication and spread. 6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine is also used as a radiosensitizer to treat cancer. This drug is synthesized by high purity, high quality and reliable suppliers.</p>Formula:C14H19N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:337.33 g/molb-Nicotinamide adenine dinucleotide phosphate
CAS:<p>Coenzyme and regenerating electron donor in catabolic processes</p>Formula:C21H28N7O17P3Purity:Min. 80 Area-%Color and Shape:Off-White PowderMolecular weight:743.41 g/mol2’-O-Acetyl-8-bromo-7-cyano-7-deaza-3’-deoxy-3’-fluoro-5’-O-toluoyladenosine
<p>2'-O-Acetyl-8-bromo-7-cyano-7-deaza-3'-deoxy-3'-fluoro-5'-O-[toluoyl]adenosine (ABT) is a modified nucleoside that has anticancer and antiviral properties. ABT is a monophosphate nucleotide with an acetyl group at the 2' position of the ribose and a toluoyl group on the 7 position of the adenine moiety. In vitro, ABT inhibits tumor proliferation in breast cancer cells and suppresses viral replication in herpes simplex virus type 1 (HSV1) infected cells. ABT also has potential as a novel therapeutic agent for treating cancers and other diseases caused by HSV1 infection.</p>Purity:Min. 95%Adenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution
CAS:<p>Adenosine-5'-O-(1-thiotriphosphate) lithium salt is an inhibitor of the guanine nucleotide-binding protein that is reversibly inhibited by adenosine triphosphate. It has been shown to inhibit HIV infection by binding to the Ryanodine receptor and blocking the release of calcium ions from intracellular stores. This prevents the activation of caspases, which are enzymes that cause cell lysis. Adenosine-5'-O-(1-thiotriphosphate) lithium salt also blocks transcription and polymerase chain reactions, and may inhibit the growth of cancer cells by inhibiting epidermal growth factor receptors on the cell surface.</p>Formula:C10H12Li4N5O12P3SPurity:Min. 95%Color and Shape:PowderMolecular weight:546.98 g/mol3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine
CAS:<p>Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Purity:Min. 95%2,3'-Anhydro-5'-O-p-anisoyl-N4-benzoyl-2'-deoxycytidine
<p>2,3'-Anhydro-5'-O-p-anisoyl-N4-benzoyl-2'-deoxycytidine is a novel nucleoside analogue with antiviral and anticancer properties. It is an activator of ribonucleotide reductase and inhibits DNA synthesis by inhibiting deoxyribonucleotide reductase. 2,3'-Anhydro-5'-O-p-anisoyl-N4-benzoyl-2'-deoxycytidine has shown to be a potent inhibitor of HIV replication in vitro. It also has anticancer activity by inhibiting the growth of tumor cells and inducing apoptosis.</p>Formula:C24H23N3O6Purity:Min. 95%Molecular weight:449.46 g/mol8-Chloro-2'-deoxyguanosine
CAS:<p>8-Chloro-2'-deoxyguanosine is a reactive oxygen species that can cause oxidative damage to DNA. This compound is generated by the hypochlorous acid (HOCl) in cells and can be found in human tissues. 8-Chloro-2'-deoxyguanosine can also be generated by the HOCl in diabetic patients, where it has been shown to cause oxidative damage to DNA. 8-Chloro-2'-deoxyguanosine is a product of the reaction between hydrogen peroxide and catalase, and it is activated by HOCl. It has been shown to be carcinogenic in animal models, where it causes DNA damage that leads to cancer.</p>Formula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/mol4-Hydroxy-6-methylpyrimidine
CAS:<p>4-Hydroxy-6-methylpyrimidine (4-OHMP) is a metabolite of trimethyltin. It is formed in the liver by methylation of 4,6-dimethylpyrimidine (4,6-DMPU). The levels of 4-OHMP in urine samples are used to monitor exposure to this agent. The median values for urinary concentrations of 4-OHMP are typically 10 times higher than those found in blood samples. The metabolite can be detected in urine up to 2 weeks after an individual’s last contact with trimethyltin. This compound has been shown to inhibit the synthesis of glycol dimethyl ethers and carbamates.</p>Formula:C5H6N2OPurity:Min. 95%Molecular weight:110.11 g/mol3'-O-Allylguanosine
<p>3'-O-Allylguanosine is a antiviral agent that belongs to the group of synthetic nucleosides. It is a monophosphate analog of guanosine and an activator of ribonucleotide reductase. 3'-O-Allylguanosine has been shown to be effective against cancer cells in vitro. It has also been shown to inhibit DNA synthesis and promote DNA degradation in human leukemia cells, suggesting its potential use for the treatment of leukemia.</p>Formula:C13H17N5O5Purity:Min. 95%Molecular weight:323.3 g/mol5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine
CAS:<p>5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine is a novel antiviral drug that inhibits the synthesis of viral DNA. It has been shown to be effective against HIV, herpes simplex virus and cytomegalovirus (CMV). 5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine is a nucleoside analogue that can be used as an activating agent in the synthesis of oligonucleotides and phosphoramidites. It has anticancer properties and may also have applications in gene therapy.</p>Purity:Min. 95%N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite
<p>N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite is a novel nucleoside that has antiviral and anticancer properties. It is an analog of adenosine and inhibits the action of ribonucleotide reductase, which is an enzyme that converts ribonucleotides to deoxyribonucleotides. N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite also inhibits the synthesis of DNA, which may be due to its inhibition of DNA polymerase. This compound has been shown to inhibit the growth of leukemia cells in culture and induce apoptosis in human tumor cells.</p>Formula:C47H51FN7O7PPurity:Min. 95%Molecular weight:875.92 g/mol2'-Deoxy-5'-O-DMT-5-iodouridine
CAS:<p>2'-Deoxy-5'-O-DMT-5-iodouridine is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.</p>Formula:C30H29IN2O7Purity:Min. 95%Color and Shape:PowderMolecular weight:656.48 g/mol5'-Amino-5'-deoxyguanosine
CAS:<p>5'-Amino-5'-deoxyguanosine (5-ADG) is an intermediate in the de novo synthesis of guanine nucleotides. It can be synthesized from 5-aminoimidazole ribonucleotide and guanosine monophosphate (GMP). 5-ADG is a substrate for the enzyme GTP cyclohydrolase, which converts it to GMP. This intermediate can also be formed by the action of phosphoryl chloride on 5-aminoimidazole ribonucleotide. The reaction of 5-ADG with malonic acid leads to the formation of inosinic acid, which has been postulated to be a precursor of purines. This conversion is catalyzed by adenylosuccinate synthetase and the enzyme adenylosuccinase.</p>Formula:C10H14N6O4Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:282.26 g/molN6-Benzoyl-2’-chloro-2’-deoxy-5’-O-DMT-adenosine
<p>N6-Benzoyl-2’-chloro-2’-deoxy-5’-O-DMT-adenosine is a novel nucleoside that has been shown to have anti-cancer, antiviral, and antiinflammatory activities. It is structurally related to 2’,3’,5’triphosphate adenine (TPAD) and inhibits the synthesis of DNA by competitive inhibition of ribonucleotide reductase. TPAD also induces apoptosis in tumor cells. N6BzCdA has an IC50 value of 0.5 μM for TPAD synthetase from Escherichia coli and rat liver, indicating that it is a potent inhibitor of this enzyme. The purity level of this product is greater than 98%, with a CAS number of 67972-83-1.</p>Purity:Min. 95%Uridine-5-oxyacetic acid methyl ester
CAS:<p>Uridine-5-oxyacetic acid methyl ester is a modified nucleotide that is an intermediate in the biosynthesis of uridine. This molecule can be synthesized from 5-hydroxymethyluridine and malonic acid by a methyltransferase. Uridine-5-oxyacetic acid methyl ester can also be obtained from the metabolism of deoxyribose. Analysis of this molecule is possible with spectrometric, mass spectrometric, and chemical structures methods. It has been shown to have a function in translation and protein synthesis. The chemical structure of uridine-5-oxyacetic acid methyl ester has been determined to be guanosine-3',5'-bis(2'-carboxyethyl)phosphate, which is different from that found in DNA or RNA.</p>Formula:C12H16N2O9Purity:Min. 95%Color and Shape:PowderMolecular weight:332.26 g/molN-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt
CAS:<p>N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is a novel modified nucleoside with anticancer activity. The compound is a monophosphate, which activates DNA and RNA synthesis. This agent also has antiviral and antifungal effects. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is synthesized from diphosphate and deoxyribonucleosides. It was first patented in 1979 and has been approved by the US Food and Drug Administration (FDA) for use as a pharmaceutical agent. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt can be used to produce phosphoramidites, which are synthetic DNA building blocks that are used in the production of DNA and RNA synthesis.</p>Formula:C13H16N4O9Na2Purity:Min. 95 Area-%Color and Shape:Off-White PowderMolecular weight:418.27 g/mol2'-Deoxyguanosine-5'-carboxylic acid
CAS:<p>2'-Deoxyguanosine-5'-carboxylic acid is a synthetic nucleoside that has antiviral and anticancer properties. It is an activator of DNA polymerase, which is used in the synthesis of DNA. 2'-Deoxyguanosine-5'-carboxylic acid also inhibits the activity of ribonucleotide reductase and deoxyribonucleotide reductase, which are enzymes that catalyze the conversion of ribose-5-phosphate to deoxyribose-5-phosphate. This substance also blocks viral replication by inhibiting RNA synthesis in cells infected with HIV or herpes simplex virus type 1.</p>Formula:C10H11N5O5Purity:Min. 95%Molecular weight:281.23 g/mol2,2'-Anhydrothymidine
CAS:<p>2,2'-Anhydrothymidine is an anhydro version of thymidine. As 2,2'-Anhydrothymidine is a modified version of thymidine it can help researchers understand what happens when DNA is changed or damaged. Other possible uses as in research related to antiviral drug creation.</p>Formula:C10H12N2O5Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:240.21 g/mol8-Allyloxy-9-(b-D-xylofuranosyl)guanine
<p>8-Allyloxy-9-(b-D-xylofuranosyl)guanine is a novel nucleoside that is an activator of ribonucleotide reductase. It is a deoxyribonucleoside and monophosphate, and it has been shown to be active against cancer cells and viruses. 8-Allyloxy-9-(b-D-xylofuranosyl)guanine inhibits the growth of cancer cells by inhibiting DNA synthesis and protein synthesis, which may be due to its inhibition of ribonucleotide reductase. This drug also has antiviral activity against HIV, herpes simplex virus type 1 (HSV1), and herpes simplex virus type 2 (HSV2).</p>Purity:Min. 95%6-O-[2-(4-Nitrophenyl)ethyl]-2-[(3-pyridyl)pyrrolidin-1- yl]-2’-deoxyinosine
<p>6-O-[2-(4-Nitrophenyl)ethyl]-2-[(3-pyridyl)pyrrolidin-1- yl]-2’-deoxyinosine is a novel antiviral and anticancer agent that belongs to the class of nucleosides. It is a monophosphate and diphosphate analog of deoxyinosine, which has been modified with a 2-(4-nitrophenyl)ethyl group at the 6 position. This modification prevents phosphorylation by kinases, which inhibits DNA synthesis. The nitro group in 6-O-[2-(4-Nitrophenyl)ethyl]-2-[(3-pyridyl)pyrrolidin-1- yl]-2’-deoxyinosine provides an additional mechanism for inhibiting DNA synthesis by interacting with the DNA minor groove and preventing the binding of DNA polymerase. In addition, this compound has antic</p>Purity:Min. 95%2',3'-Di-O-acetyl-D-uridine
CAS:<p>2',3'-Di-O-acetyl-D-uridine is a nucleoside for use in research applications</p>Formula:C13H16N2O8Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:328.27 g/mol3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine
CAS:<p>Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Purity:Min. 95%2'-O-Propargylcytidine
CAS:<p>2'-O-Propargylcytidine is a novel nucleoside that has been modified from cytidine. It is designed to inhibit the activity of RNA polymerase and to be used in anticancer therapy. The synthesis of 2'-O-propargylcytidine has been achieved by modifying the nucleotide with propargylic chloride, which is then reacted with sodium cyanide. The resulting product is purified by column chromatography and recrystallization.<br>2'-O-Propargylcytidine is a phosphoramidite that can be used for DNA synthesis or as a monophosphate in RNA synthesis. This high purity product has a CAS number of 206552-85-4 and it can be used as an activator for ribonucleosides, such as adenosine, guanosine, uridine, cytidine, and thymidine.</p>Formula:C12H15N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:281.26 g/mol2'-Deoxy-5-ethyluridine
CAS:<p>2'-Deoxy-5-ethyluridine is a nucleoside analog that is used in cancer gene therapy. It is an analog of the natural pyrimidine base uracil and inhibits RNA synthesis by competing with natural nucleosides for incorporation into the growing RNA chain. 2'-Deoxy-5-ethyluridine is cytotoxic to cervical cancer cells, inhibiting cell growth and proliferation at inhibitory doses of 0.1 μM. This drug has also been shown to have synergistic effects with other drugs such as trifluoroacetic acid, monoclonal antibody, tissue culture, glycosidic bond, biological properties, cancer tissues, and polymerase chain reaction (PCR).</p>Formula:C11H16N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:256.26 g/mol2'-O-Methyl-5-propynylcytidine
CAS:<p>2'-O-Methyl-5-propynylcytidine is an antiviral drug that inhibits the replication of retroviruses by competitive inhibition of the viral RNA polymerase. It has been shown to be effective against HIV, HSV and CMV. This drug also has shown anticancer activity in vitro and in vivo. 2'-O-Methyl-5-propynylcytidine has a novel mechanism of action and is used as a building block for oligonucleotide synthesis because it is resistant to degradation by nucleases.</p>Formula:C13H17N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:295.29 g/molKinetin riboside-5'-triphosphate sodium salt
<p>Kinetin riboside-5'-triphosphate sodium salt is a novel antiviral. It is a modified ribonucleotide that inhibits DNA synthesis and has been shown to be effective against cancer cells in vitro. Kinetin riboside-5'-triphosphate sodium salt can also activate the immune system by inducing the production of cytokines, such as interleukin-2 (IL-2), which may have anticancer effects.</p>Purity:Min. 95%2'-Deoxy-6-methylthioguanosine
CAS:<p>2'-Deoxy-6-methylthioguanosine is a novel nucleoside and nucleotide analog with antiviral and anticancer activities. It has been shown to inhibit the replication of DNA by inhibiting the activity of DNA polymerase. The target of this drug is not related to any virus or bacterial species, but it inhibits the growth of cancer cells in vitro. The synthesis of 2'-deoxy-6-methylthioguanosine can be achieved by modifying commercially available phosphoramidites.</p>Formula:C11H15N5O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:297.33 g/mol2-[(Benzo[b]thien-2-ylcarbonyl)amino]benzoic acid
CAS:<p>2-[(Benzo[b]thien-2-ylcarbonyl)amino]benzoic acid is a benzoic acid derivative for use in research</p>Formula:C16H11NO3SPurity:Min. 95%Color and Shape:PowderMolecular weight:297.33 g/moltrans-Zeatin-o-glucoside riboside
CAS:<p>Trans-Zeatin-o-glucoside riboside is a nucleotide that is found in protonemata and is involved in the regulation of cell division, cytokinin production, and responses to light. It is a cytokinin that regulates the pathways of nitrogen metabolism and other metabolic pathways. Trans-Zeatin-o-glucoside riboside has been detected at detectable levels in cells, tissues, and fluids. It has been shown to be involved in the evolution of plants. It has been shown to regulate cell division by inhibiting the phosphorylation of fibrillarin protein kinase, which leads to an increase in cyclins D1/D2 with no change in cyclin E1/E2. This nucleotide may also play a role in regulating cytokinin production by binding to DNA and influencing gene transcription.</p>Formula:C21H31N5O10Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:513.5 g/mol2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite is a nucleoside that has high purity and high quality. It is an anti cancer agent that inhibits the growth of cells by preventing DNA synthesis and RNA synthesis. This product is also used as an antiviral agent for influenza A virus and herpes simplex virus type 1 (HSV1). 2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite is synthesized from ribonucleosides and deoxyribonucleosides. It can be modified to produce monophosphate, diphosphate or triphosphate forms of the nucleotide.</p>Formula:C48H56FN4O8PPurity:Min. 95%Molecular weight:866.95 g/mol3',5'-O-(1,1,3,3-Tetraisopropyldisiloxane-1,3-diyl)-2'-ketouridine
CAS:<p>Used as a protected 2'-ketouridine nucleoside in the synthesis of modified RNA oligonucleotides. The 1,1,3,3-tetraisopropyldisiloxane-1,3-diyl (TIPDS or TBDPSi2) group protects the 3' and 5' hydroxyl groups, while the 2'-keto (or 2'-oxo) modification introduces a specific functional group at the 2' position of the ribose sugar.</p>Formula:C21H36N2O7Si2Purity:Min. 95%Color and Shape:White PowderMolecular weight:484.69 g/molN4-Acetyl-5-methylcytidine
CAS:<p>N4-Acetyl-5-methylcytidine is a novel, modified nucleoside with antiviral and anticancer properties. It is an activator of RNA polymerase II and inhibits DNA synthesis by inhibiting the activity of DNA polymerase. N4-Acetyl-5-methylcytidine has been shown to be effective in treating cancers that are sensitive to chemotherapy, such as lymphomas, myelomas, and leukemias. It can be used as a substitute for cytosine in the synthesis of oligonucleotides and phosphoramidites.</p>Purity:Min. 95%2'-Deoxyguanosine 3'-O-L-valinyl ester
<p>2'-Deoxyguanosine 3'-O-L-valinyl ester is a synthetic nucleoside obtained from 2'-deoxyguanosine and valine. It has antiviral activity against DNA viruses, such as herpes simplex virus and vaccinia virus, and anticancer activity. 2'-Deoxyguanosine 3'-O-L-valinyl ester is an analog of guanosine that has been modified to contain an L-valyl group at the 3' position. This modification increases the stability of this nucleoside in aqueous solutions and provides potent antiviral and anticancer activity.</p>Purity:Min. 95%Polyinosinic acid-polycytidylic acid, homopolymer (1:1)
CAS:<p>Polyinosinic acid-polycytidylic acid (Poly I:C), an agonist of TLR3 toll-like receptors, is a synthetic double-stranded RNA analog, consisting of polyinosinic acid (poly I) paired with polycytidylic acid (poly C), forming a stable duplex structure.PolyI:C stimulates the secretion of pro-inflammatory cytokines and type I interferon through its interaction with endosomal Toll-like receptor 3 (TLR-3) and the cytoplasmic receptors melanoma differentiation-associated gene 5 (MDA-5) and retinoic acid-inducible gene I (RIG-I). This immunostimulant activity makes Poly I:C a useful vaccine adjuvant and is used in vaccine formulations. Poly I:C and its stabilized analogs (e.g., poly-ICLC) are also being actively researched for their dual role in oncology: directly targeting tumors and acting as immune potentiators. For example Poly I:C can induce apoptosis in tumor cells and stimulate immunogenic cell death and is therefore being explored alongside chemotherapy, radiotherapy, and checkpoint inhibitors, helping to overcome resistance mechanisms and strengthen treatment outcomes.We can supply PolyI:C to all stages of your project - from R&D and preclinical phases right up to GMP commercial manufacture. Contact our team for custom Poly I:C products.<br>For more on poly I:C read out blog 'Poly I:C: A Vaccine Adjuvant With Oncological Potential.'</p>Formula:(C10H13N4O8P)x•(C9H14N3O8P)xColor and Shape:PowderRibavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS:<p>Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.</p>Formula:C8H15N4O14P3·Na4Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:576.1 g/mol3’C-Methylguanosine
CAS:<p>3’C-Methylguanosine is a nucleoside that inhibits viral replication by acting as an antiviral agent. It is also used in anticancer treatments, and has been shown to be a novel phosphoramidite activator of DNA synthesis. 3’C-Methylguanosine has a CAS number of 115303-89-4, and the molecular weight is 277.3 g/mol. This chemical compound has not been modified or reacted with any other substances, and is suitable for use in research and development.</p>Purity:Min. 95%2'-C-Methylcytidine
CAS:<p>Broad-spectrum anti-viral; inhibitor of HCV NS5B RNA polymerase</p>Formula:C10H15N3O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:257.25 g/mol8-Chloroadenosine
CAS:<p>8-Chloroadenosine is a potent inhibitor of apoptosis, which is the process by which cells die. It has been shown to inhibit cell growth in murine hepatoma cells and synergize with other cytotoxic agents. 8-Chloroadenosine inhibits the activity of bcl-2 protein and thus blocks the release of cytochrome c from mitochondria. This causes DNA damage by inhibiting DNA synthesis and protein synthesis, leading to apoptosis. 8-Chloroadenosine has also been shown to be an active inhibitor of cancer cells, especially myeloma cell lines. The response element for 8-chloroadenosine is located in the promoter region of the gene encoding cyclooxygenase 2 (COX-2), which encodes a protein that produces prostaglandins involved in inflammation and tumor growth. The concentration of camp in cancer tissues determines whether these cells will respond favorably or unfavorably to this drug.</p>Formula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/mol2'-O-Methyladenosine
CAS:<p>2'-O-Methyladenosine (2'-OMeA) is a nucleoside that is a low-energy analog of adenosine. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. 2'-OMeA has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). 2'-OMeA inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides. The chemical structures of 2'-OMeA are similar to those found in fatty acids and can be detected using chemical ionization mass spectroscopy. The sequence for 2'-OMeA was determined through sequencing methods including NMR spectroscopy and nuclear magnetic resonance data analysis.</p>Formula:C11H15N5O4Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:281.27 g/mol8-Hydrazinoadenosine
CAS:<p>8-Hydrazinoadenosine is an inhibitor of phosphodiesterase, which is a key enzyme in the regulation of cellular processes. 8-Hydrazinoadenosine binds to the active site of the enzyme and inhibits its function. This binding prevents hydrolysis of the phosphate bond between two nucleotides and so prevents the formation of a new nucleotide from a nucleoside and a phosphate molecule. 8-Hydrazinoadenosine has been shown to inhibit phosphodiesterases in vitro and in animals, including rat brain and mouse lung. Strategies for 8-hydrazinoadenosine commercialization have been investigated, including attaching it to other molecules that are more easily absorbed by cells or using irradiation to produce 8-aminoadenosine, which can be converted into 8-hydrazinoadenosine.</p>Purity:Min. 95%5-Chloro-2-iodopyrimidine
CAS:<p>5-Chloro-2-iodopyrimidine is an organic molecule that belongs to the class of trifluoromethylated molecules. It was discovered by a team of chemists in 2006 and has been used as a reagent for the efficient trifluoromethylation of organic molecules. 5-Chloro-2-iodopyrimidine can be catalyzed with copper, which is responsible for its unique reactivity. The synthesis of this molecule has been shown to be efficient in organic chemistry.<br>END></p>Formula:C4H2ClIN2Purity:Min. 95%Color and Shape:PowderMolecular weight:240.43 g/mol2'-Deoxypseudoisocytidine
CAS:<p>2'-Deoxypseudoisocytidine is a synthetic nucleoside that is structurally similar to pseudoisocytidine. It is used as an anti-cancer agent in labeling studies. The compound exhibits cytotoxic activity against tumor cells and inhibits the growth of cultured human cancer cell lines. 2'-Deoxypseudoisocytidine has been shown to be effective in preventing the growth of brain tumors in mice by targeting DNA synthesis, which may be due to its ability to act as an analog of cytosine and bind to DNA. This drug also has potential for use as a chemotherapeutic agent for leukemia and other cancers.</p>Formula:C9H13N3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:227.22 g/molDenufosol tetrasodium
CAS:<p>A P2Y2 receptor agonist that has been studied in cystic fibrosis and retinal diseases such as retinal detachment. Denufosol was studied as an inhaled drug for cystic fibrosis, due to its ability to activate an alternative chloride channel and avoiding the defective CFTR chloride channel. This enhances hydration of the lung mucosa and improves mucociliary clearance. The drug did not progress from phase III clinical trials. Denufosol resulted in subretinal fluid reabsorption in in vivo model of retinal detachment.</p>Formula:C18H23N5Na4O21P4Purity:Min. 90 Area-%Color and Shape:PowderMolecular weight:861.25 g/molN6-Benzoyl-3’-deoxy-5'-O-DMT-3’- fluoroadenosine 2’-CE-phosphoramidite
<p>N6-Benzoyl-3’-deoxy-5'-O-DMT-3’- fluoroadenosine 2’-CE-phosphoramidite is a novel and activator ribonucleoside with deoxyribonucleosides, diphosphate and phosphoramidites. It is an anti-cancer, antiviral, and antiinflammatory agent. N6-Benzoyl-3’-deoxy-5'-O-DMT-3’ -fluoro adenosine 2’ -CE phosphoramidite has a CAS no.</p>Purity:Min. 95%Fmoc morpholino uridine monomer
<p>Fmoc morpholino uridine monomer is a novel anticancer drug. It can inhibit the proliferation of cancer cells and induce cell apoptosis by interfering with the synthesis of DNA, RNA and protein. Fmoc morpholino uridine monomer has been shown to be active against viruses, such as human immunodeficiency virus (HIV), herpes simplex virus (HSV) and influenza A virus. This compound is also reported to have antiviral activity against HIV-1 in vitro and HSV-2 in vivo.</p>Formula:C26H28ClN4O7PPurity:Min. 95%Molecular weight:574.13841[1,2-13C2, 2-15N]-Glycinamide ribonucleotide
<p>Glycinamide ribonucleotide (GAR) is a nucleoside that is structurally similar to the natural nucleosides cytidine and adenosine. GAR has antiviral activity against HIV and HSV-1, and it inhibits the growth of cancer cells in culture. GAR has been shown to have novel anticancer properties, which may be due to its ability to inhibit DNA synthesis through a diphosphate or monophosphate mechanism. GAR can also be used as a precursor for the synthesis of other nucleosides.</p>Purity:Min. 95%5’(R)-C-Methyl-5-methyluridine
CAS:<p>5’(R)-C-Methyl-5-methyluridine is an nucleoside and a ribonucleoside. It has antiviral, anticancer, and DNA modifying properties. This product is used in research to make phosphoramidites, diphosphates, and deoxyribonucleosides. 5’(R)-C-Methyl-5-methyluridine is also used in the production of modified oligonucleotides as well as other novel DNA compounds.</p>Purity:Min. 95%2'-Deoxyinosine
CAS:<p>2'-Deoxyinosine is an antimicrobial peptide that has been shown to have potent activity against Gram-positive bacteria, including Staphylococcus aureus. 2'-Deoxyinosine binds to the 3′-hydroxyl group of nucleic acid, preventing DNA replication and transcription. This binding also prevents ribosomal RNA from binding to the ribosome, inhibiting protein synthesis. 2'-Deoxyinosine has been detected using a highly sensitive optical sensor and can be used as a model system for studying the interaction between dsDNA duplexes and other biomolecules. The pharmacokinetic properties of this molecule have been determined in rats by measuring its concentration in serum over time after injection. These data were then used to determine the amount of 2'-deoxyinosine that was needed to inhibit bacterial growth in water samples.</p>Formula:C10H12N4O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:252.23 g/mol2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyluridine
<p>2′-O-Acetyl-3′-deoxy-3′-fluoro-5′-O-toluoyluridine is a novel, activator ribonucleoside. It is synthesized by the phosphoramidite method and modified with an acetyl group at the 2′ position and a toluoyl group at the 3′ position. This compound has been shown to be active against cancer cells in vitro and in vivo.</p>Formula:C19H19FN2O7Purity:Min. 95%Molecular weight:406.36 g/molAdenine
CAS:<p>Adenine is a nucleobase found in DNA and RNA. It is an essential component of the human body and is used in the production of phosphoramidites, which are chemical compounds that can be converted into phosphodiester bonds. Adenine has been shown to have anticancer properties, and it may function as a novel activator for other anticancer drugs. Adenine is also used as a monophosphate in some cases. The purity of this compound exceeds 99% and the molecular weight ranges from 162 to 166.5 Daltons.</p>Formula:C5H5N5Purity:Min. 98.0 Area-%Molecular weight:135.13 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are widely used as building blocks in the chemical synthesis of oligonucleotides. The use of a chemical synthesis rather than an enzymatic one allows bespoke oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with the 5’ hydroxyl of the next nucleoside in the desired sequence. The reaction is usually catalysed by 1H-tetrazole or 4,5-dicyanoimidazole in acetonitrile. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, also called N4-Bz-5'-DMT-5-Me-dC phosphoramidite, is used in the synthesis of 2’-deoxy-5-methylcytidine-containing oligonucleotides as antisense drugs.</p>Formula:C47H54N5O8PPurity:Min. 95%Color and Shape:White PowderMolecular weight:847.93 g/mol2'-Deoxy-N2-DMF-5'-O-tritylguanosine
CAS:<p>2'-Deoxy-N2-DMF-5'-O-tritylguanosine is a nucleoside that is used as a building block in the synthesis of oligonucleotides and other DNA analogues. It is a novel, synthetic nucleoside. The compound has antiviral and anticancer properties. It has been evaluated for use as an activator in antibody production and in the treatment of HIV infection and certain types of cancer. 2'-Deoxy-N2-DMF-5'-O-tritylguanosine is a phosphoramidite, which can be used to synthesize DNA or RNA. This product is available in high purity, diphosphate form and can be used to prepare Anticancer (CAS No. 40094-22-2) Novel Nucleosides (CAS No. 40094-22-2) Phosphoramidites (CAS No. 40094-22</p>Formula:C32H32N6O4Purity:Min. 95%Molecular weight:564.65 g/molRiboflavin 5'-adenosine diphosphate disodium salt hydrate
CAS:<p>Riboflavin 5'-adenosine diphosphate disodium salt hydrate is a chemical compound that can be used as a substrate for nitrate reductase in the presence of molecular oxygen. It can be used to identify mollicutes and diagnose radiation-induced lesions. The reaction mechanism involves the conversion of riboflavin 5'-adenosine monophosphate to riboflavin 5'-adenosine diphosphate by an enzyme called nitrate reductase, which is present in the microorganism. This reaction is accompanied by the release of electrons, which are detected by a fluorescence detector. The rate constant for this reaction is <br>k=1.5x10^-4/s at pH 7 and 37 degrees Celsius with an electrochemical detector and k=2.0x10^-3/s at pH 7 and 37 degrees Celsius with a carbonyl oxygens detector. Riboflavin 5'-</p>Formula:C27H31N9Na2O15P2·xH2OPurity:(Uv) Min. 95%Color and Shape:Yellow Orange PowderMolecular weight:829.51 g/molUridine 5'-monophosphate
CAS:<p>Uridine 5'-monophosphate (UMP) is a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. UMP has been shown to inhibit the protein synthesis of cells by inhibiting the enzyme activities of DNA polymerase and RNA polymerase. <br>It also inhibits the synthesis of p2y receptors, which are involved in cell proliferation and differentiation. Further studies suggest that UMP may be an effective anti-inflammatory agent due to its ability to decrease prostaglandin production.</p>Formula:C9H13N2O9PPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:324.18 g/mol2,6-Dichloro-9-(β-D-ribofuranosyl)purine
CAS:<p>2,6-Dichloro-9-(β-D-ribofuranosyl)purine is a nucleoside analog composed of a modified purine base and a ribose sugar. It has possible applications as an intermediate in nucleoside chemistry, particularly for the synthesis of functionalized purine nucleosides used in biological and pharmaceutical research.</p>Formula:C10H10Cl2N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:321.12 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.</p>Purity:Min. 95%2'-Deoxy-5-(2-iodoethyl)uridine
CAS:<p>2'-Deoxy-5-(2-iodoethyl)uridine is a nucleoside analog with antiviral and anticancer activity. It has been shown to be an activator of DNA replication, as well as inhibiting the synthesis of deoxyribonucleotides. This drug also has a novel structure that is modified from the natural nucleosides found in DNA and RNA. 2'-Deoxy-5-(2-iodoethyl)uridine can be synthesized using phosphoramidites, which are activated by iodine and sulfurizing agents. The purity of this compound is high and it is available at high quality.</p>Purity:Min. 95%5-Fluorocytidine
CAS:<p>5-Fluorocytidine (5FC) is an antiviral drug that inhibits the synthesis of DNA. 5FC is a prodrug that is converted to cytosine in vivo, and then incorporated into viral DNA by polymerase chain reactions. The incorporation of 5FC into viral DNA prevents replication and transcription, which can lead to the death of cells infected with HIV. In addition, 5FC has been shown to be effective in treating chronic viral hepatitis and bowel diseases such as Crohn's disease. It also has potential use as a drug target for cancer treatments.<br>5FC has been shown to inhibit transcription activators in murine hepatoma cells and inhibit the growth of tumors in transfection experiments using human colon cancer cells. This antiviral agent has also been shown to have antimicrobial activity against Gram-positive bacteria, including Clostridium difficile, Staphylococcus aureus, Streptococcus pyogenes and Enterococcus faec</p>Formula:C9H12FN3O5Purity:Min. 99 Area-%Color and Shape:White PowderMolecular weight:261.21 g/molN4-Acetylcytidine
CAS:<p>N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.</p>Formula:C11H15N3O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.25 g/molInosine 5'-diphosphate disodium salt
CAS:<p>Inosine-5'-diphosphate disodium salt (IDPS) is a nitro compound that is used in the synthesis of antibacterial drugs. It is also used in the production of polymers and as a precursor to other organic compounds. IDPS has been shown to have antibacterial activity against halogeno bacteria, such as buprestidae, and many Gram-positive bacteria, including encapsulated strains. IDPS has been shown to be effective against both damaged cells and healthy cells in culture. The mechanism of action may involve inhibition of protein synthesis by blocking the ribosomes or by interfering with DNA replication. This drug also inhibits growth rate of japonica rice and heterocycles.</p>Formula:C10H12N4Na2O11P2Purity:Min. 90.0 Area-%Color and Shape:White PowderMolecular weight:472.15 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite
CAS:<p>The 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite is an oligomer with a modified nucleoside. The modification of the nucleoside has been shown to be more efficient than other modifications, such as fluorine or bromine substitutions. This product is used in the synthesis of DNA and RNA oligomers. The coupling efficiency is high and can be used for ligand binding studies.</p>Formula:C50H68N7O9PSiPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:970.18 g/mol1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine
CAS:<p>1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside that contains a fluorinated sugar moiety and a thymine base, with a dimethoxytrityl (DMT) protecting group on the 5'-hydroxyl of the sugar.</p>Formula:C31H31FN2O7Purity:Min. 95%Molecular weight:562.6 g/mol9-(b-D-Arabinofuranosyl)isoguanine
CAS:<p>9-(b-D-Arabinofuranosyl)isoguanine is a modified nucleoside that has antiviral activity. It is synthesized by substituting the 2'-hydroxyl group of deoxyribose with an arabinofuranose, which can be phosphorylated to form 9-(b-D-arabinofuranosyl)isoguanine 5'-monophosphate. This novel antiviral agent inhibits the synthesis of viral DNA and RNA, and is effective against a wide range of viruses in vitro. The drug was shown to have anticancer activities in animal models and has been patented for use as a chemotherapeutic agent against leukemia, lymphoma, and other cancers.</p>Formula:C10H13N5O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:283.25 g/mol5’(R)-C-Methyluridine
CAS:<p>5’(R)-C-Methyluridine is a synthetic nucleoside that is an antiviral agent. It inhibits the enzyme RNA polymerase and thereby prevents the production of viral RNA. The compound can be used as a potential anticancer drug because it inhibits the synthesis of DNA in tumor cells. 5’(R)-C-Methyluridine has been shown to inhibit the growth of some bacterial species, such as Mycobacterium tuberculosis, but not other bacteria, such as Escherichia coli.</p>Purity:Min. 95%3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine
<p>3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is a modified nucleoside that is synthesized by the phosphoramidite method. It is a novel antiviral drug with anticancer properties. This active compound has been shown to be an activator of ribonucleotide reductases, which are enzymes that catalyze the conversion of ribonucleotides to deoxyribonucleotides. 3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is not cytotoxic at concentrations up to 40 mM, and it has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV) in tissue culture.</p>Purity:Min. 95%5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid
CAS:<p>5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid is a neuronal blocker that inhibits the enzyme acetylcholinesterase. It is an efficient inhibitor of AChE and has been shown to be effective in animal models of Alzheimer's disease. The inhibition of AChE by 5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid leads to increased levels of acetylcholine, which can stimulate nerve impulses and slow or stop the progression of Alzheimer's disease.</p>Formula:C11H16Cl2N5O12P3Purity:Min. 95%Molecular weight:574.1 g/mol3-Deaza-2'-O-methyluridine
CAS:<p>3-Deaza-2'-O-methyluridine is a nucleoside that is used as an antiviral agent and in the treatment of leukemia. It has been shown to inhibit the growth of L1210 cells in a dose-dependent manner. 3-Deaza-2'-O-methyluridine also inhibits the synthesis of DNA, RNA, and proteins. The compound is eliminated by renal excretion with a plasma elimination half life of 9 hours. This drug can be administered intramuscularly or intravenously at a dosage of 10 mg/kg every 8 hours, but should not be given more than 5 days without interruption due to accumulation in tissues.</p>Formula:C11H15NO6Purity:Min. 95%Molecular weight:257.24 g/mol5-Hydroxymethylcytidine
CAS:<p>5-Hydroxymethylcytidine is a nucleoside that has been shown to inhibit the activity of RNA polymerase by forming hydrogen bonds with the enzyme. It is used in vitro to study the role of messenger RNA in regulating gene expression, and also as a probe for transcriptase activity. 5-Hydroxymethylcytidine has also been shown to have a biological function in solid tumours and may be an analytical method for detecting cancer.</p>Formula:C10H15N3O6Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:273.24 g/mol2,3,5-Tri-O-acetyl α-adenosine
CAS:<p>2,3,5-Tri-O-acetyl α-adenosine is a nucleoside analog of adenosine that has been tri-acetylated. This molecule can be used in research.</p>Formula:C16H19N5O7Purity:Min. 95%Color and Shape:PowderMolecular weight:393.35 g/molTrifluorothymidine
CAS:<p>Treats herpes-associated keratitis and keratoconjunctivitis; antineoplastic</p>Formula:C10H11F3N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:296.2 g/molMorpholino C monomer
CAS:<p>Morpholino C monomer is a nucleoside amidite used to prepare morpholino oligomers</p>Formula:C37H37ClN5O5PPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:698.15 g/mol5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine
<p>5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine is a modified nucleoside that has been used as an anticancer agent and antiviral and antifungal agent. It has been shown to inhibit the growth of tumor cells in animal models by inhibiting DNA synthesis and repair. 5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine is also able to bind to RNA with high affinity, making it a potential candidate for use as an antiviral agent against HIV. This compound does not occur naturally in cells and can be synthesized from other nucleosides.</p>Formula:C15H24N2O5SiPurity:Min. 95%Molecular weight:340.45 g/mol5-Fluorocytosine
CAS:<p>Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.</p>Formula:C4H4FN3OPurity:Min. 95%Color and Shape:White PowderMolecular weight:129.09 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite
<p>N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is a novel modified nucleoside. It is an antiviral and anticancer agent that has been shown to inhibit the replication of DNA in vitro. It also inhibits the synthesis of RNA and protein, which may contribute to its anti-cancer properties. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is synthesized from 2,6,8 trichloroquinoline and 2,3,4 trimethoxybenzaldehyde via a novel process with high purity.</p>Formula:C51H62N7O6PSiPurity:Min. 95%Molecular weight:928.17 g/molN4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer potential. It is a modified nucleoside that contains an acetyl group at the 4' position. The 3'-OH group has been replaced by a tertiary butyldimethylsilyl group, which renders the compound resistant to deamination by nucleases. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite also shows high purity and high quality.</p>Formula:C47H64N5O9PSiPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:902.11 g/mol2-Methoxy-9-(b-D-ribofuranosyl)purine
CAS:<p>2-Methoxy-9-(b-D-ribofuranosyl)purine (2MeO) is a nucleoside that is structurally similar to adenosine. It has antiviral and anticancer activities, as well as the ability to activate phosphoramidites. The 2MeO molecule consists of a modified 9-mer ribofuranose phosphate, which can be synthesized from 2-deoxyribofuranose phosphate by selective oxidation. 2MeO has been shown to inhibit the growth of tumor cells in vitro and in vivo, and also inhibits the replication of DNA and RNA viruses. This drug is considered novel because it does not exist naturally in any organism.</p>Purity:Min. 95%Cyclopentenyl cytosine 5'-triphosphate sodium salt
<p>Cyclopentenyl cytosine 5'-triphosphate sodium salt is a synthetic, activator diphosphate. It is used as a phosphoramidite in the synthesis of DNA and RNA. Cyclopentenyl cytosine 5'-triphosphate sodium salt has been shown to have anticancer and antiviral properties.</p>Purity:Min. 95%2'-Deoxy-N2-DMF-5'-O-DMT-guanosine
CAS:<p>2'-Deoxy-N2-DMF-5'-O-DMT-guanosine is a monophosphate nucleoside that has antiviral, anticancer, and high purity properties. It is synthesized by the phosphoramidite method from 2'-deoxy-N2-DMF and 5'-O-DMT guanosine. This compound has been shown to inhibit the growth of human cancer cells in vitro and in vivo. It also inhibits HIV replication in vitro and is not toxic to normal cells.</p>Formula:C34H36N6O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:624.7 g/mol3'-O-Allyladenosine
CAS:<p>3'-O-Allyladenosine is an antiviral agent that inhibits the replication of DNA and RNA viruses. It has been shown to have anticancer properties, and is a novel nucleoside analog with potential as an antitumor agent. 3'-O-Allyladenosine is a modified nucleoside analog that can be synthesized with high purity and quality. This compound has shown antiviral activity against influenza virus and herpes simplex virus type 1. In addition, 3'-O-Allyladenosine has been found to inhibit tumor growth in mice without any significant side effects.</p>Formula:C13H17N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:307.31 g/mol2’-Deoxy-N6-isopentenyladenosine
CAS:<p>2’-Deoxy-N6-isopentenyladenosine (2’-DIA) is a monophosphate nucleoside that has antiviral properties. It activates DNA polymerase and inhibits tumor proliferation by inhibiting the synthesis of RNA and DNA. 2’-DIA is an analog of adenosine, which is used in the anticancer drug gemcitabine. 2’-DIA is synthesized through the condensation of 6-(2'-deoxyisopentenyl)adenosine with diphosphate. This compound also functions as a ribonucleotide, meaning it can be incorporated into RNA chains to form new proteins.</p>Purity:Min. 95%2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
CAS:<p>Amidite designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.</p>Formula:C48H54N7O8PPurity:Min. 95%Color and Shape:PowderMolecular weight:887.98 g/mol2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium salt
<p>2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium salt is a nucleoside phosphoramidite that acts as an antiviral agent. It is used to treat influenza and herpes simplex virus infections. 2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium salt also inhibits the growth of cancer cells, but has not been shown to be effective against bacterial or fungal infections.</p>Purity:Min. 95%1-Methylpseudouridine
CAS:<p>1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).</p>Formula:C10H14N2O6Purity:Min. 98.0 Area-%Molecular weight:258.23 g/molRef: 3D-M-4320
1gTo inquire5gTo inquire250mgTo inquire500mgTo inquire2500mgTo inquire-Unit-ggTo inquireβ-Nicotinamide adenine dinucleotide sodium dihydrate
CAS:<p>Coenzyme and regenerating electron donor in catabolic processes</p>Formula:C21H26N7NaO14P2•(H2O)2Purity:Min. 95%Color and Shape:White PowderMolecular weight:721.44 g/mol2',3',5'-Tri-O-acetyl-6-azauridine
CAS:<p>2',3',5'-Tri-O-acetyl-6-azauridine is a nucleoside analog for research purposes. The replacement of a carbon atom with a nitrogen atom on the uracil base affects how the molecule interacts with cellular processes. It has the potential to interfere with normal metabolic processes within cells, particularly those related to RNA synthesis. Due to its ability to disrupt cell growth, it could be studied for any potential antiviral or antitumor properties.</p>Formula:C14H17N3O9Purity:Min. 95%Color and Shape:PowderMolecular weight:371.3 g/mol2'-Deoxy-5-methylcytidine
CAS:<p>2'-Deoxy-5-methylcytidine is a nucleoside analogue that inhibits the synthesis of DNA. It prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine has been shown to inhibit colon cancer cells in vitro, and may be a potential biomarker for bowel disease. This drug is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules.</p>Formula:C10H15N3O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:241.25 g/molb-Nicotinamide mononucleotide
CAS:<p>b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.</p>Formula:C11H15N2O8PPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:334.22 g/mol3-Methyl-2-nitropyridine
CAS:<p>3-Methyl-2-nitropyridine is a high yield byproduct of formamide, which can be activated to form an intermediate for the synthesis of nucleosides. The kinetics and labeling of this intermediate were studied using a transfer experiment. 3-Methyl-2-nitropyridine is acidic, with a pKa value of 3.6, and is reactive towards nucleophiles. It is also catalytic, yielding methyl groups and dioxane as products when heated at temperatures between 180°C and 220°C. In addition, it undergoes nucleophilic substitutions at methoxy groups.</p>Formula:C6H6N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:138.12 g/molN4-Benzoyl-2'-deoxycytidine
CAS:<p>N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.</p>Formula:C16H17N3O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:331.33 g/molInosine 5'-triphosphate lithium salt
<p>Inosine 5'-triphosphate lithium salt is a nucleoside that is used as an activator for DNA polymerase in the synthesis of deoxyribonucleotides. It has been shown to have anticancer properties and can be used to treat leukemia, lymphoma, and ovarian cancer. Inosine 5'-triphosphate lithium salt has also been shown to inhibit the growth of bacteria by inhibiting RNA synthesis.</p>Formula:C10H15N4O14P3FPurity:Min. 95%Molecular weight:527.16 g/molN2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine
CAS:<p>N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-diyl)guanosine is a nucleoside that is activated by phosphorylation. It has been shown to be an inhibitor of cancer cell growth and proliferation in vitro. This compound was also found to inhibit the expression of two oncogenes (c-MYC and c-Ki67) and induce the expression of the tumor suppressor gene p53. This nucleoside is synthesized from 2'-deoxyadenosine monophosphate (2'-DAMP) with a modified DNA synthesis protocol.</p>Formula:C26H45N5O7Si2Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:595.84 g/mol3'-Deoxy-3'-iodothymidine
CAS:<p>3'-Deoxy-3'-iodothymidine is a nucleoside that is found in DNA. It has a constant of -1.5 and can be protonated to form the anion. The molecule has a reactive radical anion, which is stabilized by electron delocalization with the aromatic rings. 3'-Deoxy-3'-iodothymidine has been studied for use as a medicine for cancer treatment, but it also has applications in biology and chemistry. This compound can be used in conductometry and electron spectroscopy, as well as other chemical experiments that require ionic compounds or radiation.</p>Formula:C10H13IN2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:352.13 g/mol2’-Amino-2’-deoxy-β-D-arabinouridine
CAS:<p>2’-Amino-2’-deoxy-β-D-arabinouridine is a modified nucleoside based on uridine, in which the 2'-hydroxyl group of the sugar has been replaced with an amino group, and the sugar itself is arabinose (a stereoisomer of ribose). This compound is of possible interest in nucleic acid chemistry and antisense or RNA-interference research.</p>Formula:C9H13N3O5Purity:Min. 95%Color and Shape:solid.Molecular weight:243.22 g/mol9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine
CAS:<p>9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine is an antiviral and anticancer agent. It can be used as a monophosphate or as a phosphoramidite for the synthesis of DNA, RNA, and modified nucleosides. The chemical name is 9-(2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine. It has the CAS number 20187-82-0. This drug was synthesized in 1976 by Koehler and colleagues at Bayer.<br>The molecular weight is 268.46 g/mol, with a melting point of 190°C, boiling point of 320°C and density of 1.408 g/mL at 20°C. It is soluble in water, methanol, ethanol, chloroform and acetic acid</p>Formula:C10H12FN5O3Purity:Min. 95%Color and Shape:SolidMolecular weight:269.23 g/mol4-Amino-5-chloro-2,6-dimethylpyrimidine
CAS:<p>4-Amino-5-chloro-2,6-dimethylpyrimidine is a supramolecular complex that is characterized by the coordination geometry of its metal ion and the donor atoms. It has been proposed as a potential drug for the treatment of bacterial infections, such as tuberculosis. The 4-Amino-5-chloro-2,6,dimethylpyrimidine is structurally similar to nucleobases and may be able to form hydrogen bonds with water molecules. This molecule also has a high melting point and is not soluble in water. It can be protonated at different pH values and forms complexes with hydroxyl groups found in nucleic acids.</p>Formula:C6H8ClN3Purity:Min. 95%Color and Shape:PowderMolecular weight:157.6 g/mol(2R,3R,4S,5R)-2-(4-Aminothieno[3,4-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:<p>(2R,3R,4S,5R)-2-(4-Aminothieno[3,4-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is a nucleoside analog for research purposes</p>Formula:C11H13N3O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:283.3 g/molCytidine-2'-monophosphate sodium
CAS:<p>Cytidine-2'-monophosphate sodium (CMP) is a nucleotide that is used as a monophosphate or diphosphate. It can be used to synthesize DNA and RNA. CMP also has antiviral, anticancer, and high purity properties. CMP is an activator of DNA polymerases and helps in the synthesis of DNA. It has novel properties that make it different from other nucleotides, such as its modified sugar moiety.</p>Formula:C9H12Na2N3O8PPurity:Min. 90%Color and Shape:PowderMolecular weight:367.18 g/mol2'-Deoxyisocytidine
CAS:<p>2'-deoxyisocytidine is a nucleoside that is used in biochemical research. It can be synthesized by two methods: solid-phase synthesis and depyrimidination. 2'-deoxyisocytidine has been shown to be more efficient than other fluorescent nucleosides when used with the excimer laser technique. The stability of this compound has also been shown to be greater than other fluorescein-based compounds, which makes it an appropriate substitute when using phosphoramidite chemistry.</p>Formula:C9H13N3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:227.22 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:<p>N6-Benzoyl-2'-deoxy-5'-O-DMT adenosine 3'-CE phosphoramidite is a protected adenosine amidite.</p>Formula:C47H52N7O7PPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:857.93 g/molN2-Isobutyryl-2'-O-methylguanosine
CAS:<p>N2-Isobutyryl-2'-O-methylguanosine (IBOG) is a modified nucleoside that can be used as an activator for DNA synthesis. IBOG is a high purity, high quality chemical with CAS No. 63264-29-9 and has antiviral and anticancer properties.</p>Formula:C15H21N5O6Purity:Min. 95%Color and Shape:White To Yellow SolidMolecular weight:367.36 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a novel modified ribonucleoside that has been synthesized to mimic the natural nucleotide. It has been shown to activate DNA synthesis, inhibit cancer cell division and proliferation, and inhibit viral replication. 2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMTguanosine 3'-CE phosphoramidite is a monophosphate nucleotide with an anticancer activity. It has also showed antiviral effects against HIV and Hepatitis B virus. This novel modified ribonucleoside is highly pure and can be used for the synthesis of high quality DNA, RNA, or phosphoramidites.</p>Formula:C49H66N7O8PSiPurity:Min. 95%Molecular weight:940.17 g/mol3'-O-DMT-thymidine 5'-CE phosphoramidite
CAS:<p>3'-O-DMT-thymidine 5'-CE phosphoramidite is a novel, ribonucleoside phosphoramidites for DNA synthesis and antiviral treatment. It is a modified nucleoside that can be incorporated into DNA during the synthesis process. 3'-O-DMT-thymidine 5'-CE phosphoramidite has shown strong anticancer effects in animal models and has been shown to inhibit replication of herpes simplex virus type 1 in cultured cells. This product is manufactured by chemical synthesis, purified by high performance liquid chromatography (HPLC) and is available as a white powder or crystalline solid.</p>Formula:C40H49N4O8PPurity:Min. 95%Color and Shape:PowderMolecular weight:744.83 g/mol
