Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,687 products)
- Apoptosis(6,097 products)
- Cell Cycle/Checkpoint(4,691 products)
- Chromatin/Epigenetics(2,376 products)
- Cytoskeletal Signaling(1,472 products)
- DNA Damage/DNA Repair(2,921 products)
- Endocrinology/Hormones(3,611 products)
- Enzyme(3,655 products)
- GPCR/G-Protein(8,755 products)
- Immunology and Inflammation(3,765 products)
- Influenza Virus(298 products)
- JAK/STAT signaling(407 products)
- MAPK Signaling(1,230 products)
- Membrane Transporter/Ion Channel(2,947 products)
- Metabolism(9,940 products)
- Microbiology/Virology(7,347 products)
- Neuroscience(10,240 products)
- Other Inhibitors(36,533 products)
- Oxidation-Reduction(43 products)
- PI3K/Akt/mTOR Signaling(1,437 products)
- Proteases/Proteasome(1,675 products)
- Stem Cell and Derivatives(830 products)
- Tyrosine Kinase/Adaptors(2,028 products)
- Ubiquitination(1,682 products)
Show 16 more subcategories
Found 66582 products of "Inhibitors"
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JAK1-IN-11
CAS:<p>JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations with IC50 values of 0.02 nM (JAK1) and 0.</p>Formula:C26H36N6O4SPurity:98%Color and Shape:SolidMolecular weight:528.67S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Formula:C25H26F3NO3Purity:98%Color and Shape:SolidMolecular weight:445.47Immune cell migration-IN-1
CAS:<p>Immune cell migration-IN-1 (compound 2) serves as a potent inhibitor of immune cell migration, with potential research applications for mitigating conditions</p>Formula:C30H25ClN4O6SColor and Shape:SolidMolecular weight:605.06FLT3-IN-19
CAS:<p>FLT3-IN-19 (Comp 50) is a potent, selective inhibitor of FLT3, demonstrating an IC50 value of 0.213 nM, and is applicable in research pertaining to acute</p>Formula:C22H26N8OColor and Shape:SolidMolecular weight:418.49ATR-IN-24
CAS:<p>ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].</p>Formula:C23H26N6O2Purity:98%Color and Shape:SolidMolecular weight:418.49Tauro-Obeticholic Acid sodium
CAS:<p>Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid.</p>Formula:C28H48NO6S·NaColor and Shape:SolidMolecular weight:549.74Antibacterial agent 160
CAS:<p>Antibacterial Agent 160 is a potent antibacterial agent that rapidly eradicates bacteria and inhibits the formation of bacterial biofilms.</p>Formula:C29H27ClFN3O6Color and Shape:SolidMolecular weight:567.99Bumetanide sodium
CAS:Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).Formula:C17H19N2NaO5SColor and Shape:SolidMolecular weight:386.4DiaFluo
CAS:<p>DiaFluo is a probe for protein S-sulfinylation from cells.</p>Formula:C32H32N4O9SColor and Shape:SolidMolecular weight:648.69Ref: TM-T31416
Discontinued productMDVN1003
CAS:MDVN1003 inhibits BTK & PI3Kδ in B cells, blocking NHL growth; it kills lymphoma cells, not erythroblasts.Formula:C22H20FN7OPurity:98%Color and Shape:SolidMolecular weight:417.44Azilsartan mepixetil potassium
CAS:<p>Azilsartan medoxomil potassium (QR-01019K), an angiotensin II receptor antagonist, exhibits a potent and sustained antihypertensive effect, along with a more</p>Formula:C36H33KN6O8Color and Shape:SolidMolecular weight:716.78Antitumor photosensitizer-2
CAS:<p>Compound 11, also known as Antitumor Photosensitizer-2, is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-</p>Formula:C40H47N5O7Color and Shape:SolidMolecular weight:709.83Antitumor photosensitizer-1
CAS:<p>Antitumor Photosensitizer-1 (Compound 8) is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity,</p>Formula:C42H51N5O6Color and Shape:SolidMolecular weight:721.88I-BET282
CAS:<p>BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1 (example 2, plC50: 6.0 - 7.0).</p>Formula:C25H30N4O4Purity:98%Color and Shape:SolidMolecular weight:450.53Antitumor agent-104
CAS:<p>Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor cells, primarily through the inhibition of PARP1 enzyme</p>Formula:C31H33FN6O3Purity:98%Color and Shape:SolidMolecular weight:556.63Omeprazole acid
CAS:Omeprazole treats GERD, ulcers, Zollinger-Ellison syndrome, prevents GI bleeding; it's a proton pump inhibitor.Formula:C34H32N6Na2O10S2Color and Shape:SolidMolecular weight:794.76Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan
CAS:<p>Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan is a linker molecule employed in the synthesis of antibody-drug conjugates (ADCs), demonstrating potent antitumor</p>Formula:C55H60FN9O13Color and Shape:SolidMolecular weight:1074.12Bi-Mc-VC-PAB-MMAE
CAS:<p>Bi-Mc-VC-PAB-MMAE is an agent-linker conjugate for antibody-drug conjugates (ADCs), featuring the linker (Fmoc-Val-Cit-PAB) and the potent tubulin inhibitor (</p>Formula:C71H104N12O18Color and Shape:SolidMolecular weight:1413.66URAT1 inhibitor 5
CAS:<p>URAT1 Inhibitor 5 (compound 16) serves as a powerful inhibitor of URAT1 and is utilized in hyperuricemia research [1].</p>Formula:C18H14BrN3O2SColor and Shape:SolidMolecular weight:416.29Sakura 6
CAS:<p>Sakura 6, a synthetic serotonin transporter (SERT)-binding peptide, enhances the interaction between SERT and neuronal nitric oxide synthase.</p>Formula:C31H45N5O7Color and Shape:SolidMolecular weight:599.73Cap-dependent endonuclease-IN-9
CAS:<p>Cap-dependent endonuclease-IN-9, a strong influenza inhibitor, shows low toxicity, good pharmacokinetics, and dynamic action.</p>Formula:C29H22F2N4O7SPurity:98%Color and Shape:SolidMolecular weight:608.57(αR)-Cyclopropaneacetamide-Exatecan
CAS:<p>(αR)-Cyclopropaneacetamide-Exatecan (compound 2-A), an Exenotecan derivative, serves as a cytotoxic agent that effectively inhibits the proliferation of U87MG</p>Formula:C29H28FN3O6Color and Shape:SolidMolecular weight:533.55BTK-IN-25
CAS:<p>BTK-IN-25 (compound 71) is a potent BTK inhibitor, demonstrating an IC50 of 0.77 nM against BTK(C481S) and achieving an IC50 of 1 nM in DOHH2 cells [1].</p>Formula:C28H27F2N3O5Purity:98%Color and Shape:SolidMolecular weight:523.53Estrogen receptor modulator 8
CAS:<p>Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells</p>Formula:C25H24F4N2O2Purity:98%Color and Shape:SolidMolecular weight:460.46FAP-IN-2
CAS:<p>FAP-IN-2 is a 99mTc-labeled, isonitrile-containing derivative of a fibroblast activation protein (FAPI) inhibitor suitable for tumor imaging [1].</p>Formula:C24H28F2N6O3Color and Shape:SolidMolecular weight:486.51BTK-IN-27
CAS:<p>BTK-IN-27 (example 8), a potent BTK inhibitor with an IC50 of 0.2 nM, demonstrates anti-proliferative effects in TMD8 cells with an IC50 of less than 5 nM.</p>Formula:C31H35N7O2Purity:98%Color and Shape:SolidMolecular weight:537.66VISTA-IN-2
CAS:<p>VISTA-IN-2 (Compound 1) is a V-domain Ig suppressor of T-cell activation (VISTA) inhibitor that promotes the degradation of VISTA in cells via autophagy,</p>Formula:C23H23N3OPurity:98%Color and Shape:SolidMolecular weight:357.45PI3Kδ-IN-13
CAS:<p>PI3Kδ-IN-13 (compound 89), with an IC50 value of 2.6 nM, is an inhibitor of PI3Kδ, applicable for researching diseases involving cell proliferation, including</p>Formula:C27H39N7O4S2Color and Shape:SolidMolecular weight:589.77RIOK2-IN-2
CAS:<p>RIOK2-IN-2 (8) functions as an inhibitor of RIOK2, exhibiting IC50 values of 3.02 μM in MKN-1 cells and 5.34 μM in MOLT4 cells [1].</p>Formula:C27H23F3N6O2Color and Shape:SolidMolecular weight:520.51VMAT2-IN-2 tosylate
CAS:<p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>Formula:C27H36F3NO6SPurity:98%Color and Shape:SolidMolecular weight:559.64JDB175
CAS:<p>JDB175, a selective BTK inhibitor with oral bioavailability, demonstrates excellent penetration through the blood-brain barrier.</p>Formula:C26H21F3N4O2Purity:98%Color and Shape:SolidMolecular weight:478.47AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Formula:C29H40O3Purity:99.58%Color and Shape:SolidMolecular weight:436.63Civorebrutinib
CAS:<p>Civorebrutinib (WS-413) is an inhibitor of Bruton's tyrosine kinase that exhibits antineoplastic activity [1].</p>Formula:C23H22ClN7O2Color and Shape:SolidMolecular weight:463.92IDO/Tubulin-IN-2
CAS:<p>IDO/Tubulin-IN-2 inhibits TDO/tubulin, effective on U87, HepG2, A549, HCT-116, LO2 cancer cells; IC50 values 0.036-1.04 μM, boosts antitumor action.</p>Formula:C48H40N6O10Color and Shape:SolidMolecular weight:860.87Anti-MI/R injury agent 1
CAS:<p>Anti-MI/R injury agent 1 (compound 18), derived from Panaxatriol, represents an orally administered, potent agent against myocardial ischemia/reperfusion (MI/R</p>Formula:C32H49NO6Color and Shape:SolidMolecular weight:543.73URAT1&XO inhibitor 1
CAS:<p>URAT1&XO Inhibitor 1 (compound 29) serves as a dual inhibitor with IC50 values of approximately 10 μM for URAT1 and 1.01 μM for Xanthine Oxidase.</p>Formula:C20H13N5O3SPurity:98%Color and Shape:SolidMolecular weight:403.41Tibremciclib
CAS:<p>Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].</p>Formula:C28H32F2N8Purity:98%Color and Shape:SolidMolecular weight:518.6Xilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Formula:C26H37N3O2Purity:98%Color and Shape:SolidMolecular weight:423.59CIAC001
CAS:<p>CIAC001, a pyruvate kinase PKM2 inhibitor, exhibits anti-neuroinflammatory properties.</p>Formula:C20H25N3O2Color and Shape:SolidMolecular weight:339.43SHP2-IN-14
CAS:<p>SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM.</p>Formula:C22H20Cl2N8OColor and Shape:SolidMolecular weight:483.35HBV-IN-38
CAS:<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Formula:C18H16F3N5O4S2Purity:98%Color and Shape:SolidMolecular weight:487.48Belfosdil
CAS:Belfosdil is a blocker of antihypertensive calcium channel.Formula:C27H50O7P2Purity:98%Color and Shape:SolidMolecular weight:548.63And1-IN-1
CAS:<p>And1-IN-1, also known as compound III, is a potent inhibitor of And1 [1].</p>Formula:C15H11BCl2O2Color and Shape:SolidMolecular weight:304.96Insecticidal agent 6
CAS:<p>Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.</p>Formula:C19H14BrCl2N5O4Purity:98%Color and Shape:SolidMolecular weight:527.16JAK-IN-27
CAS:<p>JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS family kinases, displaying inhibitory concentrations (IC50s) of 3.0 nM</p>Formula:C20H21F2N7OPurity:98%Color and Shape:SolidMolecular weight:413.42MDL-811
CAS:<p>MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine residues 9, 18, and 56 (H3K9Ac, H3K18Ac, and H3K56Ac),</p>Formula:C25H25BrCl2FN3O5S2Purity:98%Color and Shape:SolidMolecular weight:681.42Antibacterial agent 157
CAS:<p>Compound B12 (Antibacterial agent 157) is a fungicidal agent that can impact protein synthesis in Botrytis cinerea.</p>Formula:C26H23BrF4N2O3Color and Shape:SolidMolecular weight:567.37Davelizomib
CAS:<p>Davelizomib is a proteasome inhibitor that exhibits antineoplastic activity [1].</p>Formula:C21H26BF2N3O7Purity:98%Color and Shape:SolidMolecular weight:481.25Igermetostat
CAS:<p>Igermetostat, an EZH2 inhibitor, is utilized both in vivo and in vitro for cancer research [1].</p>Formula:C32H46N4O4Purity:98%Color and Shape:SolidMolecular weight:550.73I5B2
CAS:<p>I5B2 is a novel phosphorus-containing angiotensin I converting enzyme inhibitor. Angiotensin I converting enzyme is produced by Actinomadura sp.</p>Formula:C23H32N3O7PPurity:98%Color and Shape:SolidMolecular weight:493.49Lerzeparib
CAS:<p>Lerzeparib is a PARP (ADP-ribose polymerase) inhibitor that exhibits antineoplastic activity [1].</p>Formula:C21H20FN3O2Purity:98%Color and Shape:SolidMolecular weight:365.4DDO-2213
CAS:<p>DDO-2213 is a potent, orally active inhibitor of the WDR5-MLL1 interaction, demonstrating an IC50 of 29 nM and a Kd of 72.9 nM against WDR5.</p>Formula:C24H27ClFN7OColor and Shape:SolidMolecular weight:483.97MOR agonist-1
CAS:<p>MOR Agonist-1 is a μ-opioid receptor (MOR) agonist noted for its potent analgesic properties and is utilized in research concerning pain and associated</p>Formula:C22H26ClFN2O2Purity:98%Color and Shape:SolidMolecular weight:404.91S-72
CAS:<p>S-72 acts as a microtubule polymerization inhibitor, effective in cell-free assays at concentrations of 1, 3, and 10 µM.</p>Formula:C20H22N4O3SColor and Shape:SolidMolecular weight:398.50BET-IN-14
CAS:<p>BET-IN-14 is a pan BET inhibitor with an IC50 of 5.35 nM, demonstrating oral activity and anticancer properties [1].</p>Formula:C30H37N7O2Purity:98%Color and Shape:SolidMolecular weight:527.66JAK1-IN-10
CAS:<p>JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor of JAK1 [1].</p>Formula:C15H17N7Purity:98%Color and Shape:SolidMolecular weight:295.34SARS-CoV-2-IN-68
CAS:<p>SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger</p>Formula:C14H12N2OSePurity:98%Color and Shape:SolidMolecular weight:303.22CYY292
CAS:<p>CYY292 is a chemical compound acting as an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3, with respective IC50 values of 5.35, 4.6, 28, 28, and 78 nM.</p>Formula:C24H28N8OColor and Shape:SolidMolecular weight:444.53DPP
CAS:<p>DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating</p>Formula:C36H40Cl2N2O10PtPurity:98%Color and Shape:SolidMolecular weight:926.7CGP 56999A
CAS:CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.Formula:C19H30NO5PPurity:98%Color and Shape:SolidMolecular weight:383.42LFS-1107
CAS:<p>LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].</p>Formula:C12H11N5OS2Purity:98%Color and Shape:SolidMolecular weight:305.38Canlitinib
CAS:<p>Canlitinib, a tyrosine kinase inhibitor, holds potential for cancer research.</p>Formula:C33H31F2N3O7Purity:98%Color and Shape:SolidMolecular weight:619.61BBDDL2059
CAS:<p>BBDDL2059 is a selective covalent inhibitor targeting EZH2, exhibiting an IC50 of 1.5 nM against the EZH2-Y641F mutant.</p>Formula:C27H36N4O4SPurity:98%Color and Shape:SolidMolecular weight:512.66BCR-ABL-IN-8
CAS:<p>BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].</p>Formula:C30H33N7O5Purity:98%Color and Shape:SolidMolecular weight:571.63L 689037
CAS:L 689037 is an inhibitor of leukotriene biosynthesis.Formula:C36H37ClN2O4Purity:98%Color and Shape:SolidMolecular weight:597.14LT-540-717
CAS:<p>LT-540-717 (compound 32), a potent FLT3 inhibitor (IC50=0.62 nM), exhibits antiproliferative activity and effectively inhibits various acquired FLT3 mutations,</p>Formula:C24H24N8O2Color and Shape:SolidMolecular weight:456.5ROCK2-IN-6
CAS:<p>ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].</p>Formula:C26H21F2N7OPurity:98%Color and Shape:SolidMolecular weight:485.49TrkB-IN-1
CAS:<p>TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) properties.</p>Formula:C19H16N2O6Purity:98%Color and Shape:SolidMolecular weight:368.34Syk-IN-8
CAS:<p>Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.</p>Formula:C23H26N10Purity:98%Color and Shape:SolidMolecular weight:442.52STAT3-IN-18
CAS:<p>STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and</p>Formula:C18H24Cl2N2O6PtPurity:98%Color and Shape:SolidMolecular weight:630.38JAK-IN-34
CAS:<p>JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3,</p>Formula:C27H26N6OPurity:98%Color and Shape:SolidMolecular weight:450.53Yhhu6669
CAS:<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Formula:C29H28ClFN6O3Purity:98%Color and Shape:SolidMolecular weight:563.02PHI-101
CAS:<p>PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.</p>Formula:C19H19FN4O2SPurity:99.4%Color and Shape:SolidMolecular weight:386.44ROCK-IN-6
CAS:<p>ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1</p>Formula:C19H19N5O8SPurity:98%Color and Shape:SolidMolecular weight:477.45DG026
CAS:DG026 selectively inhibits IRAP, reducing its cross-presentation in dendritic cells without affecting ERAP1.Formula:C35H40N3O4PPurity:98%Color and Shape:SolidMolecular weight:597.68hDHODH-IN-8
<p>hDHODH-IN-8 is a potent human dihydroorotic dehydrogenase (hDHODH) inhibitor (IC50: 16 nM) that exhibits potent antiproliferative effects and has good water solubility, with potential for oncology studies, especially in lymphoma.</p>Formula:C21H15F6N3O4Purity:98%Molecular weight:487.35Cortivazol
CAS:Cortivazol is an Anti-Inflammatory Drug.Formula:C32H38N2O5Purity:98%Color and Shape:SolidMolecular weight:530.65Ifetroban sodium
CAS:<p>Ifetroban sodium (BMS-180291), oral TXA2/PGH2 antagonist for researching heart, stroke, BP, thrombosis.</p>Formula:C25H31N2NaO5Color and Shape:SolidMolecular weight:462.522BPH-628
CAS:<p>BPH-628 is a bioactive chemical.</p>Formula:C20H20O7P2Color and Shape:SolidMolecular weight:434.32Dimethandrolone Undecanoate
CAS:Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.Formula:C31H50O3Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:470.73Ref: TM-T27176
Discontinued productIfetroban
CAS:<p>Ifetroban is a potent and selective TxA2/PGH2 receptor antagonist.</p>Formula:C25H32N2O5Color and Shape:SolidMolecular weight:440.53ALS-I-41
CAS:ALS-I-41 is a novel, potent and selective antagonist of oxytocin receptor.Formula:C30H38FN3O6SPurity:98%Color and Shape:SolidMolecular weight:587.7
