Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,523 products)
- Apoptosis(5,792 products)
- Cell Cycle/Checkpoint(4,449 products)
- Chromatin/Epigenetics(2,238 products)
- Cytoskeletal Signaling(1,383 products)
- DNA Damage/DNA Repair(2,825 products)
- Endocrinology/Hormones(3,507 products)
- Enzyme(3,640 products)
- GPCR/G-Protein(8,333 products)
- Immunology and Inflammation(3,526 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(404 products)
- MAPK Signaling(1,202 products)
- Membrane Transporter/Ion Channel(2,790 products)
- Metabolism(9,448 products)
- Microbiology/Virology(6,981 products)
- Neuroscience(9,926 products)
- Other Inhibitors(37,926 products)
- Oxidation-Reduction(41 products)
- PI3K/Akt/mTOR Signaling(1,400 products)
- Proteases/Proteasome(1,597 products)
- Stem Cell and Derivatives(831 products)
- Tyrosine Kinase/Adaptors(2,016 products)
- Ubiquitination(1,650 products)
Show 16 more subcategories
Found 66641 products of "Inhibitors"
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CYY292
CAS:<p>CYY292 is a chemical compound acting as an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3, with respective IC50 values of 5.35, 4.6, 28, 28, and 78 nM.</p>Formula:C24H28N8OColor and Shape:SolidMolecular weight:444.53IDO1-IN-22
CAS:<p>IDO1-IN-22 (Compound 3) is an inhibitor of IDO1, demonstrating potent activity with biochemical hIDO1 IC50 of 67.4 nM and HeLa hIDO1 IC50 of 17.6 nM.</p>Formula:C12H12BrFN6O3Purity:98%Color and Shape:SolidMolecular weight:387.16FAP-IN-2
CAS:<p>FAP-IN-2 is a 99mTc-labeled, isonitrile-containing derivative of a fibroblast activation protein (FAPI) inhibitor suitable for tumor imaging [1].</p>Formula:C24H28F2N6O3Color and Shape:SolidMolecular weight:486.51BTK-IN-25
CAS:<p>BTK-IN-25 (compound 71) is a potent BTK inhibitor, demonstrating an IC50 of 0.77 nM against BTK(C481S) and achieving an IC50 of 1 nM in DOHH2 cells [1].</p>Formula:C28H27F2N3O5Purity:98%Color and Shape:SolidMolecular weight:523.53HPK1-IN-38
CAS:<p>HPK1-IN-38 (compound 15) is an inhibitor of MAP4K1/HPK1, suitable for research into disorders related to HPK1 [1].</p>Formula:C29H29N5O3Color and Shape:SolidMolecular weight:495.57And1-IN-1
CAS:<p>And1-IN-1, also known as compound III, is a potent inhibitor of And1 [1].</p>Formula:C15H11BCl2O2Color and Shape:SolidMolecular weight:304.96TrkB-IN-1
CAS:<p>TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) properties.</p>Formula:C19H16N2O6Purity:98%Color and Shape:SolidMolecular weight:368.34EST73502
CAS:<p>EST73502 is a compound that functions as a dual agonist for the μ-opioid receptor (MOR) and an antagonist for the σ1 receptor (σ1R). It is selective, orally active, and possesses the ability to penetrate the blood-brain barrier (BBB). The compound exhibits a Ki value of 64 nM for the MOR and 118 nM for the σ1R. Additionally, EST73502 demonstrates antinociceptive activity [1].</p>Formula:C19H26F2N2O2Purity:98%Color and Shape:SolidMolecular weight:352.426diMal-O-CH2COOH
CAS:<p>DiMal-O-CH2COOH is a cleavable linker utilized in antibody-drug conjugates (ADCs).</p>Formula:C13H12N2O7Color and Shape:SolidMolecular weight:308.24Antibacterial agent 157
CAS:<p>Compound B12 (Antibacterial agent 157) is a fungicidal agent that can impact protein synthesis in Botrytis cinerea.</p>Formula:C26H23BrF4N2O3Color and Shape:SolidMolecular weight:567.37Cap-dependent endonuclease-IN-9
CAS:<p>Cap-dependent endonuclease-IN-9, a strong influenza inhibitor, shows low toxicity, good pharmacokinetics, and dynamic action.</p>Formula:C29H22F2N4O7SPurity:98%Color and Shape:SolidMolecular weight:608.57URAT1 inhibitor 5
CAS:<p>URAT1 Inhibitor 5 (compound 16) serves as a powerful inhibitor of URAT1 and is utilized in hyperuricemia research [1].</p>Formula:C18H14BrN3O2SColor and Shape:SolidMolecular weight:416.29Anti-MI/R injury agent 1
CAS:<p>Anti-MI/R injury agent 1 (compound 18), derived from Panaxatriol, represents an orally administered, potent agent against myocardial ischemia/reperfusion (MI/R</p>Formula:C32H49NO6Color and Shape:SolidMolecular weight:543.73Belfosdil
CAS:<p>Belfosdil is a blocker of antihypertensive calcium channel.</p>Formula:C27H50O7P2Purity:98%Color and Shape:SolidMolecular weight:548.63Py-MAA-Val-Cit-PAB-MMAE
CAS:<p>Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties.</p>Formula:C72H111N13O16SColor and Shape:SolidMolecular weight:1446.79Tauro-Obeticholic Acid sodium
CAS:<p>Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid.</p>Formula:C28H48NO6S·NaColor and Shape:SolidMolecular weight:549.74DDO-2213
CAS:<p>DDO-2213 is a potent, orally active inhibitor of the WDR5-MLL1 interaction, demonstrating an IC50 of 29 nM and a Kd of 72.9 nM against WDR5.</p>Formula:C24H27ClFN7OColor and Shape:SolidMolecular weight:483.97Antitumor agent-104
CAS:<p>Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor cells, primarily through the inhibition of PARP1 enzyme</p>Formula:C31H33FN6O3Purity:98%Color and Shape:SolidMolecular weight:556.63AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Formula:C29H40O3Purity:99.58%Color and Shape:SolidMolecular weight:436.63ATR-IN-24
CAS:<p>ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].</p>Formula:C23H26N6O2Purity:98%Color and Shape:SolidMolecular weight:418.49Civorebrutinib
CAS:<p>Civorebrutinib (WS-413) is an inhibitor of Bruton's tyrosine kinase that exhibits antineoplastic activity [1].</p>Formula:C23H22ClN7O2Color and Shape:SolidMolecular weight:463.92Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE
CAS:<p>Compound S6, Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE, is a potent anticancer agent specifically activated by the tumor microenvironment; it demonstrates efficacy</p>Formula:C67H101N11O16Purity:98%Color and Shape:SolidMolecular weight:1316.58LT-540-717
CAS:<p>LT-540-717 (compound 32), a potent FLT3 inhibitor (IC50=0.62 nM), exhibits antiproliferative activity and effectively inhibits various acquired FLT3 mutations,</p>Formula:C24H24N8O2Color and Shape:SolidMolecular weight:456.5IDO/Tubulin-IN-2
CAS:<p>IDO/Tubulin-IN-2 inhibits TDO/tubulin, effective on U87, HepG2, A549, HCT-116, LO2 cancer cells; IC50 values 0.036-1.04 μM, boosts antitumor action.</p>Formula:C48H40N6O10Color and Shape:SolidMolecular weight:860.87Davelizomib
CAS:<p>Davelizomib is a proteasome inhibitor that exhibits antineoplastic activity [1].</p>Formula:C21H26BF2N3O7Purity:98%Color and Shape:SolidMolecular weight:481.25Mal-VC-PAB-PNP-CDN-A
CAS:<p>Mal-VC-PAB-PNP-CDN-A is a conjugate comprised of an agent and a linker, utilized in antibody-drug conjugates (ADC) [1] [2].</p>Formula:C51H67N17O20P2Color and Shape:SolidMolecular weight:1300.13JAK-IN-34
CAS:<p>JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3,</p>Formula:C27H26N6OPurity:98%Color and Shape:SolidMolecular weight:450.53S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Formula:C25H26F3NO3Purity:98%Color and Shape:SolidMolecular weight:445.47YK-029A
CAS:<p>YK-029A, an orally active EGFR mutant inhibitor, targets both EGFR T790M and EGFRex20ins mutations.</p>Formula:C27H32N8O2Purity:98%Color and Shape:SolidMolecular weight:500.6(αR)-Cyclopropaneacetamide-Exatecan
CAS:<p>(αR)-Cyclopropaneacetamide-Exatecan (compound 2-A), an Exenotecan derivative, serves as a cytotoxic agent that effectively inhibits the proliferation of U87MG</p>Formula:C29H28FN3O6Color and Shape:SolidMolecular weight:533.55I-BET282
CAS:<p>BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1 (example 2, plC50: 6.0 - 7.0).</p>Formula:C25H30N4O4Purity:98%Color and Shape:SolidMolecular weight:450.53PHI-101
CAS:<p>PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.</p>Formula:C19H19FN4O2SPurity:99.4%Color and Shape:SolidMolecular weight:386.44Cortivazol
CAS:<p>Cortivazol is an Anti-Inflammatory Drug.</p>Formula:C32H38N2O5Purity:98%Color and Shape:SolidMolecular weight:530.65ALS-I-41
CAS:<p>ALS-I-41 is a novel, potent and selective antagonist of oxytocin receptor.</p>Formula:C30H38FN3O6SPurity:98%Color and Shape:SolidMolecular weight:587.7Dimethandrolone Undecanoate
CAS:<p>Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.</p>Formula:C31H50O3Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:470.73Ref: TM-T27176
Discontinued producthDHODH-IN-8
<p>hDHODH-IN-8 is a potent human dihydroorotic dehydrogenase (hDHODH) inhibitor (IC50: 16 nM) that exhibits potent antiproliferative effects and has good water solubility, with potential for oncology studies, especially in lymphoma.</p>Formula:C21H15F6N3O4Purity:98%Molecular weight:487.35DG026
CAS:<p>DG026 selectively inhibits IRAP, reducing its cross-presentation in dendritic cells without affecting ERAP1.</p>Formula:C35H40N3O4PPurity:98%Color and Shape:SolidMolecular weight:597.68BPH-628
CAS:<p>BPH-628 is a bioactive chemical.</p>Formula:C20H20O7P2Color and Shape:SolidMolecular weight:434.32Ifetroban
CAS:<p>Ifetroban is a potent and selective TxA2/PGH2 receptor antagonist.</p>Formula:C25H32N2O5Color and Shape:SolidMolecular weight:440.53ROCK-IN-6
CAS:<p>ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1</p>Formula:C19H19N5O8SPurity:98%Color and Shape:SolidMolecular weight:477.45Ifetroban sodium
CAS:<p>Ifetroban sodium (BMS-180291), oral TXA2/PGH2 antagonist for researching heart, stroke, BP, thrombosis.</p>Formula:C25H31N2NaO5Color and Shape:SolidMolecular weight:462.522
