Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,524 products)
- Apoptosis(5,793 products)
- Cell Cycle/Checkpoint(4,452 products)
- Chromatin/Epigenetics(2,242 products)
- Cytoskeletal Signaling(1,382 products)
- DNA Damage/DNA Repair(2,826 products)
- Endocrinology/Hormones(3,507 products)
- Enzyme(3,640 products)
- GPCR/G-Protein(8,333 products)
- Immunology and Inflammation(3,527 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(404 products)
- MAPK Signaling(1,203 products)
- Membrane Transporter/Ion Channel(2,792 products)
- Metabolism(9,449 products)
- Microbiology/Virology(6,981 products)
- Neuroscience(9,926 products)
- Other Inhibitors(37,921 products)
- Oxidation-Reduction(41 products)
- PI3K/Akt/mTOR Signaling(1,400 products)
- Proteases/Proteasome(1,597 products)
- Stem Cell and Derivatives(830 products)
- Tyrosine Kinase/Adaptors(2,015 products)
- Ubiquitination(1,650 products)
Show 16 more subcategories
Found 66639 products of "Inhibitors"
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SENP2-IN-1
CAS:<p>SENP2-IN-1 selectively inhibits SENP2, SENP1, and SENP5 with low IC50 values; useful in cancer studies.</p>Formula:C32H29N3O5S2Color and Shape:SolidMolecular weight:599.72ERRγ agonist-1
<p>ERRγ agonist-1 can be used in neuropsychological disorders research.</p>Formula:C17H21N5OColor and Shape:SolidMolecular weight:311.38Anticancer agent 28
<p>Anticancer agent 28 is 50x more potent than Oridonin, IC50 of 0.09 μM against K562; effective in H22 mouse tumors.</p>Formula:C28H33NO6Color and Shape:SolidMolecular weight:479.56HPK1-IN-30
CAS:<p>HPK1-IN-30 is a potent inhibitor of HPK1. HPK1-IN-30 has potential for cancer disease research.</p>Formula:C25H23FN6Color and Shape:SolidMolecular weight:426.49DNA gyrase B-IN-1
<p>DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.</p>Formula:C23H18ClF3N6O4SColor and Shape:SolidMolecular weight:566.94Pefcalcitol
CAS:<p>Pefcalcitol is a novel antipsoriatic prodrug candidate containing a 16-en-22-oxa-vitamin D3 structure.</p>Formula:C26H34F5NO4Color and Shape:SolidMolecular weight:519.54MtTMPK-IN-2
CAS:<p>MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).</p>Formula:C23H24ClN3O3Color and Shape:SolidMolecular weight:425.91KRAS G12C inhibitor 56
CAS:<p>KRAS G12C inhibitor 56, a powerful inhibitor of SOS1 with an inhibitory concentration (IC50) of 1.6 nM, holds promise for use in cancer research.</p>Formula:C32H39N7O4SColor and Shape:SolidMolecular weight:617.76JAK3-IN-11
CAS:<p>JAK3-IN-11: potent oral JAK3 inhibitor (IC50=1.7 nM), noncytotoxic, >588-fold selectivity, blocks T-cell growth; useful in autoimmune research.</p>Formula:C23H23N5O2Color and Shape:SolidMolecular weight:401.46PXS-5153A monohydrochloride
CAS:<p>PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 <40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.</p>Formula:C20H25Cl2FN4O2SPurity:98%Color and Shape:Odour SolidMolecular weight:475.41EGFR-IN-58
<p>EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.</p>Formula:C31H30FN7OColor and Shape:SolidMolecular weight:535.61DS89002333
<p>DS89002333: oral PRKACA inhibitor with 0.3 nM IC50, effective against FL-HCC with DNAJB1-PRKACA fusion in xenografts.</p>Formula:C22H20ClF2N3O3Color and Shape:SolidMolecular weight:447.86MLKL-IN-6
<p>MLKL-IN-6 (compound P28) is a mixed lineage kinase inhibitor that specifically targets the Mixed Lineage Kinase domain-like (MLKL) protein.</p>Formula:C20H18N4O5Purity:98%Color and Shape:SolidMolecular weight:394.38Dehydrocrenatidine
CAS:<p>Dehydrocrenatidine (Kumujian G) is an inhibitor of JAK and induces cell apoptosis.</p>Formula:C15H14N2O2Purity:98%Color and Shape:SolidMolecular weight:254.28Mopivabil
<p>Mopivabil is the angiotensin II receptor antagonist[1].</p>Formula:C14H20O3Color and Shape:SolidMolecular weight:236.31Elongation factor P-IN-2
<p>Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.</p>Formula:C16H35N3O2Color and Shape:SolidMolecular weight:301.47MtDTBS-IN-1
<p>MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.</p>Formula:C16H16N4O5Color and Shape:SolidMolecular weight:344.32E6201
CAS:<p>E6201, a dual kinase inhibitor, blocks MEK1/FLT3 and has anti-tumor/psoriasis effects with low IC50s: ERK2 (5.2 nM), JNK (91 nM), p38 MAPK (19 nM).</p>Formula:C21H27NO6Color and Shape:SolidMolecular weight:389.44Freselestat
CAS:<p>Freselestat (ONO-6818) inhibits neutrophil elastase, reduces interleukin 8, C5B-9, and inflammation in cardiopulmonary bypass.</p>Formula:C23H28N6O4Color and Shape:SolidMolecular weight:452.51Ciluprevir
CAS:<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formula:C40H50N6O8SPurity:98%Color and Shape:SolidMolecular weight:774.93VEGFR-IN-3
CAS:<p>VEGFR-IN-3 inhibits cancer cell growth (OVCAR-4, MDA-MB-468) with IC50s: 0.29, 0.35μM. Used in cancer research.</p>Formula:C27H28N2O6Color and Shape:SolidMolecular weight:476.52DSP-1053 benzenesulfonate
CAS:<p>DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.</p>Formula:C32H38BrNO7SColor and Shape:SolidMolecular weight:660.62DJT06001
CAS:<p>DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding.</p>Formula:C21H20ClN3O5SColor and Shape:SolidMolecular weight:461.92CLK1/2-IN-1
CAS:<p>CLK1/2-IN-1 is a CLK1 and CLK2 inhibitor and it also inhibits SRPK1 and SRPK2.</p>Formula:C21H20F3N7OPurity:98%Color and Shape:SolidMolecular weight:443.428-iso Prostaglandin F3α
CAS:<p>8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA.</p>Formula:C20H32O5Color and Shape:SolidMolecular weight:352.47BU09059
CAS:<p>BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).</p>Formula:C28H37N3O5Purity:98%Color and Shape:SolidMolecular weight:495.61Nonsteroidal aromatase inhibitor 1
<p>Compound 13h, a nonsteroidal aromatase inhibitor, has a potent IC50 of 0.09 nM against CYP19A1, showing promise for breast cancer research.</p>Formula:C22H16N4O2Color and Shape:SolidMolecular weight:368.39Luffariellolide
CAS:<p>Luffariellolide is a terpene compound obtained from the marine sponge Hyrtios communis that is an HSF-PLA2 inhibitor and a RAR agonist.</p>Formula:C25H38O3Purity:98%Color and Shape:SolidMolecular weight:386.57WEHI-539
CAS:<p>WEHI-539 is a selective Bcl-XL inhibitor (IC50: 1.1 nM).</p>Formula:C31H29N5O3S2Purity:98%Color and Shape:SolidMolecular weight:583.72Anticancer agent 14
<p>Anticancer agent 14: a potent breast cancer inhibitor; induces cell death, disrupts mito. membrane potential (IC50: 0.20-0.65 μM).</p>Formula:C29H34N2O3Color and Shape:SolidMolecular weight:458.59Falecalcitriol
CAS:<p>Falecalcitriol is an analog of calcitriol. It has a higher potency both in vivo and in vitro systems, which is longer duration of action in vivo.</p>Formula:C27H38F6O3Purity:98%Color and Shape:SolidMolecular weight:524.58GYKI-53784
CAS:<p>GYKI-53784 (LY 303070) is an effective selective AMPA receptor antagonist.</p>Formula:C19H20N4O3Color and Shape:SolidMolecular weight:352.39Ranakinin
CAS:<p>Ranakinin is a novel tachykinin receptor agonist; from the brain of frog, Rana ridibunda.</p>Formula:C62H95N17O15SColor and Shape:SolidMolecular weight:1350.59GAT564
<p>GAT564, an allosteric CB1R modulator, shows EC50s of 87 nM (cAMP) & 320 nM (β-arrestin2) and lowers IOP effectively in glaucoma mice.</p>Formula:C20H16N2O2SColor and Shape:SolidMolecular weight:348.42PD-1/PD-L1-IN-30
CAS:<p>PD-1/PD-L1-IN-30: Cancer research inhibitor with 0.018 μM IC50.</p>Formula:C29H28F3NO5Color and Shape:SolidMolecular weight:527.5322-HDHA
CAS:<p>22-HDHA is an oxidation product of docosahexaenoic acid .</p>Formula:C22H32O3Color and Shape:SolidMolecular weight:344.49AY 17,605
CAS:<p>AY 17,605 is an inhibitor of bovine heart and rat brain nucleoside-3',5'- monophosphate phosphodiesterase.</p>Formula:C25H36O5Color and Shape:SolidMolecular weight:416.55Topoisomerase II inhibitor 5
<p>Topoisomerase II inhibitor 5 (Compound E24) is a DNAtopoisomerase II inhibitor with anticancer effects.</p>Formula:C26H27N5O4Color and Shape:SolidMolecular weight:473.52Verrucarin A
CAS:<p>Verrucarin A, a mycotoxin from Myrothecium verrucaria, inhibits protein synthesis, leukemia growth, and triggers apoptosis.</p>Formula:C27H34O9Color and Shape:SolidMolecular weight:502.55AT-IAP
CAS:AT-IAP is an effective dual antagonist of XIAP and cIAP1.Formula:C29H40FN5O2Purity:98%Color and Shape:SolidMolecular weight:509.66Z-FY-CHO
CAS:<p>Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.</p>Formula:C26H26N2O5Purity:95.88%Color and Shape:SolidMolecular weight:446.5LPM4870108
<p>LPM4870108: Potent, oral pan-Trk inhibitor, selective over ALK, with anti-tumor effects. TrkC IC50=0.2nM, TrkA IC50=2.4nM.</p>Formula:C20H19FN6O3Color and Shape:SolidMolecular weight:410.4IDH1 Inhibitor 1
CAS:<p>Oral, brain-penetrant mutant IDH1 inhibitor targeting R132H/C with IC50: 0.021/0.045μM; 2.52μM for IDH1WT.</p>Formula:C20H18F4N6O2Purity:98%Color and Shape:SolidMolecular weight:450.39Mepixetil
<p>Mepixetil is a potent angiotensin II receptor antagonist[1].</p>Formula:C12H18N2O3Color and Shape:SolidMolecular weight:238.28Sulprostone
CAS:<p>EP3 and EP1 receptor agonist</p>Formula:C23H31NO7SPurity:98%Color and Shape:White To Off-White SolidMolecular weight:465.56Plumbemycin B
CAS:<p>Plumbemycin B is isolated from Streptomyces plumbeus; an L-threonine antagonist.</p>Formula:C12H21N4O8PColor and Shape:SolidMolecular weight:380.29U75302
CAS:<p>U75302 is an antagonist of thymosin beta-4 (TB4) receptor with a Ki value of 159 nM on guinea pig lung membranes.</p>Formula:C22H35NO3Purity:98%Color and Shape:Light Yellow OilMolecular weight:361.52ML-SI1
CAS:<p>ML-SI1, a racemic mixture of diastereoisomers, is a TRPML inhibitor and acts on TRPML1 (IC50: 15 μM).</p>Formula:C23H26Cl2N2O3Color and Shape:SolidMolecular weight:449.37PF-07202954
CAS:<p>PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against</p>Formula:C22H23FN6O3Purity:98%Color and Shape:SolidMolecular weight:438.45KRAS inhibitor-21
CAS:<p>KRAS inhibitor-21 (22b) is a KRAS G12C inhibitor (IC50<0.01 μM) that can be used in cancer research.</p>Formula:C33H41N5O3Color and Shape:SolidMolecular weight:555.71Cav 3.2 inhibitor 2
<p>Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.</p>Formula:C32H37F2N3OColor and Shape:SolidMolecular weight:517.65Icariside F2
CAS:<p>Icariside F2 modestly inhibits α-glucosidase (4.6-12%) and has antioxidant properties, plus strong NF-κB inhibition (IC50: 16.25±2.19 μM).</p>Formula:C18H26O10Purity:98%Color and Shape:SolidMolecular weight:402.39CYP121A1-IN-1
<p>CYP121A1-IN-1: Strong inhibitor for CYP121A1, hinders Mycobacterium tuberculosis growth (MIC 90 ~6.25 μM), reduces mycocyclosin synthesis.</p>Formula:C22H20N4OColor and Shape:SolidMolecular weight:356.42RWJ-445167
CAS:<p>RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.</p>Formula:C18H24N6O5SPurity:98%Color and Shape:SolidMolecular weight:436.49SR121566A
CAS:<p>SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).</p>Formula:C20H25N5O4SPurity:98%Color and Shape:SolidMolecular weight:431.51GSK3368715 3HCl
CAS:<p>GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81</p>Formula:C20H41Cl3N4O2Purity:98%Color and Shape:SolidMolecular weight:475.92J-104132
CAS:<p>J-104132: potent human ETA/B antagonist; Ki: ETA=0.034nM, ETB=0.104nM; prevents ET-1 effects, ED50 i.v.=0.045mg/kg, p.o.=0.35mg/kg.</p>Formula:C31H33NO7Purity:98%Color and Shape:SolidMolecular weight:531.60HIV-1 inhibitor-17
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).</p>Formula:C32H32N4O5SColor and Shape:SolidMolecular weight:584.69Anticancer agent 65
CAS:<p>Anticancer agent 65: Effective on A549 cells, IC50 1.07 μM, halts S phase, triggers apoptosis, elevates p53/p21, causes ROS and MMP collapse.</p>Formula:C36H63NO5Color and Shape:SolidMolecular weight:589.89Anticancer agent 29
<p>Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).</p>Formula:C22H15ClFNOColor and Shape:SolidMolecular weight:363.81(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formula:C14H10ClN3S2Color and Shape:SolidMolecular weight:319.83Chitin synthase inhibitor 1
<p>Potent, selective CHS inhibitor with 0.12 mM IC50; effective against drug-resistant fungi.</p>Formula:C22H20ClN3O3Color and Shape:SolidMolecular weight:409.87NNC-11-1585
CAS:<p>NNC-11-1585 is an M(1) and M(2) muscarinic acetylcholine receptor (mAChR) agonist.</p>Formula:C18H19N3OSColor and Shape:SolidMolecular weight:325.43RAD51-IN-5
CAS:<p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>Formula:C26H38N4O5S2Color and Shape:SolidMolecular weight:550.73URAT1 inhibitor 2
<p>URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.</p>Formula:C21H18BrN3O2SColor and Shape:SolidMolecular weight:456.36Epiderstatin
CAS:<p>Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.</p>Formula:C15H20N2O4Color and Shape:SolidMolecular weight:292.33ATM-3507 trihydrochloride (1861449-70-8 free base)
<p>ATM-3507 trihydrochloride is a potent tropomyosin inhibitor (IC50s: 3.83-6.84 μM in human melanoma cell lines).</p>Formula:C37H49Cl3FN5O2Purity:98%Color and Shape:SolidMolecular weight:721.17SS-RJW100
<p>SS-RJW100 is an enantiomer of RJW100 targeting LRH-1, SF-1, enhances Tif2 interaction, and disrupts LRH-1 networks with lowered stability.</p>Formula:C28H34OColor and Shape:SolidMolecular weight:386.57Antileishmanial agent-6
<p>Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.</p>Formula:C24H26O8Color and Shape:SolidMolecular weight:442.46ONO-8809
CAS:<p>ONO-8809: Thromboxane A2 antagonist, reduces airway hyperresponse, macrophage accumulation, and MMP-9 in SHRSP brains.</p>Formula:C30H46BrNO4SPurity:98%Color and Shape:SolidMolecular weight:596.66Rimegepant sulfate hydrate
CAS:<p>Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.</p>Formula:C56H64F4N12O13SColor and Shape:SolidMolecular weight:1221.25264,5'-Dimethylangelicin-NHS
<p>NHS-modified coumarin, 4,5'-Dimethylangelicin-NHS, shows photochemical activity & photosensitivity.</p>Formula:C21H19NO7SColor and Shape:SolidMolecular weight:429.44Aeroplysinin 1
CAS:<p>Aeroplysinin I is an antibacterial compound from the sponge. It has cytotoxic activity against colon cancer cells by promoting β-catenin degradation.</p>Formula:C9H9Br2NO3Color and Shape:SolidMolecular weight:338.98HDAC6-IN-13
<p>HDAC6-IN-13: potent, selective HDAC6 inhibitor; oral; IC50=0.019μM; targets HDAC1/2/3; crosses blood-brain barrier; anti-inflammatory.</p>Formula:C23H22N4OColor and Shape:SolidMolecular weight:370.45ZM514
<p>ZM514 inhibits CD73 (hCD73 IC50: 1.39 μM, mCD73 IC50: 14.65 μM) with low cytotoxicity, suitable for cancer research.</p>Formula:C36H57NO4Color and Shape:SolidMolecular weight:567.84ABD957
CAS:<p>ABD957: covalent ABHD17 depalmitoylases inhibitor, IC50 0.21µM for ABHD17B, blocks N-Ras, halts NRAS-mutant AML cell growth.</p>Formula:C27H36F3N7O5SColor and Shape:SolidMolecular weight:627.68FGFR3-IN-4
CAS:<p>FGFR3-IN-4 is a selective inhibitor targeting FGFR3, demonstrating an IC50 value of under 50 nM.</p>Formula:C26H24ClN7OColor and Shape:SolidMolecular weight:485.97RMS5
CAS:<p>RMS5: hambanine analogue, inhibits P-gp, anti-cancer with cytotoxic, anti-proliferative effects, reduces Bcl-2 proteins, cleaves PARP.</p>Formula:C35H38N2O5SColor and Shape:SolidMolecular weight:598.75P-gp modulator 2
<p>P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.</p>Formula:C22H20BrN3O4Color and Shape:SolidMolecular weight:470.32PF-06305591 dihydrate
<p>PF-06305591 dihydrate is a potent and highly selective voltage gated sodium channel NaV1.8 blocker (IC 50 = 15 nM) with an excellent preclinical in vitro ADME</p>Formula:C15H26N4O3Color and Shape:SolidMolecular weight:310.39BTK inhibitor 18
<p>BTK inhibitor 18 is a selective, potent, covalent, orally active Btk inhibitor (IC50: 142 nM) that exhibits anti-inflammatory effects.</p>Formula:C29H25N5O4S2Color and Shape:SolidMolecular weight:571.67Tubulin polymerization-IN-6
<p>Compound 5f, a potent tubulin polymerization inhibitor (IC50 = 1.09 μM), blocks cell migration, tube formation, and has anti-angiogenic effects.</p>Formula:C19H21NO7Color and Shape:SolidMolecular weight:375.37LSD1-IN-21
<p>LSD1-IN-21: potent LSD1 inhibitor, crosses blood-brain barrier, IC50 of 0.956 μM; lowers TNF-α, anti-cancer, anti-inflammatory.</p>Formula:C24H25N5O2SColor and Shape:SolidMolecular weight:447.55AHR antagonist 5 hemimaleate
<p>Potent oral AHR antagonist with IC50 < 0.5 μM, hinders tumor growth with anti-PD-1.</p>Formula:C29H28FN7O4Color and Shape:SolidMolecular weight:499.55ZD6021
CAS:<p>ZD6021 is an antagonist of neurokinin 1 receptor.</p>Formula:C35H35Cl2N3O2SPurity:98%Color and Shape:SolidMolecular weight:632.64nAChR antagonist 1
CAS:<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Formula:C19H22N4O2Color and Shape:SolidMolecular weight:338.4K-14585
CAS:<p>K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.</p>Formula:C51H56Cl2N8O4Color and Shape:SolidMolecular weight:915.95SARS-CoV-2-IN-6
<p>SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.</p>Formula:C17H13ClN2O2Color and Shape:SolidMolecular weight:312.75SMP-797 HCl
CAS:<p>SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.</p>Formula:C34H44ClN5O4Purity:98%Color and Shape:SolidMolecular weight:622.20SCP1-IN-2
<p>SCP1-IN-2: potent, selective SCP1 inhibitor; induces REST degradation, hinders its activity, may study REST-driven glioblastoma growth.</p>Formula:C19H17F3N2O6S2Color and Shape:SolidMolecular weight:490.47(±)-J 113397
CAS:<p>(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).</p>Formula:C24H37N3O2Color and Shape:SolidMolecular weight:399.57YW3-56
CAS:<p>YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.</p>Formula:C27H32ClN5O2Color and Shape:SolidMolecular weight:494.03YCW-E11
CAS:<p>YCW-E11 is an antiapoptotic Bcl-2 family proteins inhibitor.</p>Formula:C25H21Cl2N3O6S2Purity:98%Color and Shape:SolidMolecular weight:594.49COX-2/PI3K-IN-2
<p>COX-2/PI3K-IN-2 (5f): anti-inflammatory & anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).</p>Formula:C16H17N5O2Color and Shape:SolidMolecular weight:311.34LPA5 antagonist 1
<p>LPA5 antagonist 1: selective, potent (IC50=32 nM), high brain permeability, studies inflammatory/neuropathic pain.</p>Formula:C28H26N2O4SColor and Shape:SolidMolecular weight:486.58DN-F01
<p>DN-F01 exhibits a potent calcium-dependent inhibitory effect on cardiac myofibrillar ATPase activity, with an IC50 of 11 ± 4 nmol/L.</p>Formula:C22H16N2O2Color and Shape:SolidMolecular weight:340.37CYP2C1/CYP2C19-IN-2
<p>CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.</p>Formula:C27H28N2O6SColor and Shape:SolidMolecular weight:508.59DNA-PK-IN-6
CAS:<p>DNA-PK-IN-6 inhibits DNA-PKcs, disrupting tumor DNA repair and triggering apoptosis; enhances radiotherapy and targets various tumors (WO2021197159A1).</p>Formula:C19H21N7OColor and Shape:SolidMolecular weight:363.42MsbA-IN-5
<p>MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.</p>Formula:C23H19Cl2N5OColor and Shape:SolidMolecular weight:452.34DBCO-SS-PEG4-Biotin
<p>DBCO-SS-PEG4-Biotin: cleavable ADC linker with 4-unit PEG, used in ADC synthesis.</p>Formula:C45H62N6O9S3Purity:98%Color and Shape:SolidMolecular weight:927.22,3-dinor-11β-Prostaglandin F2α
CAS:<p>2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where</p>Formula:C18H30O5Color and Shape:SolidMolecular weight:326.43MI-1851
CAS:<p>MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.</p>Formula:C34H53N15O6Color and Shape:SolidMolecular weight:767.88Antimalarial agent 9
<p>Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.</p>Formula:C28H32BrN3O2Color and Shape:SolidMolecular weight:522.48TD-0212
CAS:TD-0212: Oral dual antagonist for AT1 (pKi 8.9) & NEP inhibitor (pIC50 9.2).Formula:C28H34FN3O4SPurity:98%Color and Shape:SolidMolecular weight:527.65MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Formula:C26H35FN16O2Purity:98%Color and Shape:SolidMolecular weight:622.66NK1 receptor antagonist 2
CAS:<p>NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research.</p>Formula:C31H35F7N4O2Color and Shape:SolidMolecular weight:628.62C5aR-IN-3
CAS:<p>C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.</p>Formula:C36H40FN5O3Color and Shape:SolidMolecular weight:609.73NBTIs-IN-5
CAS:<p>NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.</p>Formula:C24H25F3N4O2Color and Shape:SolidMolecular weight:458.48Scytonemin
CAS:<p>Scytonemin, a cyanobacterial pigment, inhibits cancer cell growth by decreasing Plk1 activity, especially effective on U266 myeloma cells.</p>Formula:C36H20N2O4Color and Shape:SolidMolecular weight:544.55EB-0156
<p>EB-0156: potent ER α-glucosidase inhibitor, IC50 of 0.0479/ <0.001 μM, N-substituted valerian, broad-spectrum antiviral potential.</p>Formula:C21H32N6O7Color and Shape:SolidMolecular weight:480.51KAG-308
CAS:<p>KAG-308: selective EP4 agonist; Ki: 2.57 nM, EC50: 17 nM; suppresses colitis, promotes mucosal healing, inhibits TNF-α.</p>Formula:C24H30F2N4O3Purity:98%Color and Shape:SolidMolecular weight:460.52IRAK4-IN-12
<p>IRAK4-IN-12 (compound 37) is a potent inhibitor of IRAK4 (IC50: 0.015 μM) with cellular pIRAK4 potency (IC50: 0.5 μM).</p>Formula:C24H31FN8OColor and Shape:SolidMolecular weight:466.55L 671776
CAS:<p>L 671776 is an inositol monophosphatase inhibitor.</p>Formula:C23H32O5Purity:98%Color and Shape:SolidMolecular weight:388.5AChE/BChE-IN-1
<p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>Formula:C32H35ClN6O3Color and Shape:SolidMolecular weight:587.11Dictyostatin
CAS:<p>Dictyostatin: potent microtubule stabilizer & anticancer agent with antiproliferative effects; researched for tauopathies.</p>Formula:C32H52O6Color and Shape:SolidMolecular weight:532.75HIV-1 inhibitor-18
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).</p>Formula:C27H31N3O6SColor and Shape:SolidMolecular weight:525.62BRD4 D1-IN-1
<p>BRD4 D1-IN-1 selectively inhibits BRD4 D1 (IC50 <0.092 μM, Kd 18 nM) with >500-fold specificity versus D2.</p>Formula:C32H37F3N6OColor and Shape:SolidMolecular weight:578.67TK-129
<p>TK-129: Oral KDM5B inhibitor, IC50=44 nM, low-toxicity, cardioprotective, aids in heart disease research.</p>Formula:C15H23N5O2Color and Shape:SolidMolecular weight:305.38Beloxepin
CAS:<p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>Formula:C19H21NO2Purity:98%Color and Shape:SolidMolecular weight:295.38Daeatal
CAS:<p>Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.</p>Formula:C56H93N19O10Purity:98%Color and Shape:SolidMolecular weight:1192.46NYX-2925
CAS:<p>NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.</p>Formula:C14H23N3O4Color and Shape:SolidMolecular weight:297.35Lunacalcipol
CAS:<p>Lunacalcipol is used for the treatment of Secondary Hyperparathyroidism.</p>Formula:C28H42O4SColor and Shape:SolidMolecular weight:474.7FNC-TP trisodium
<p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>Formula:C9H11FN6Na3O13P3Color and Shape:SolidMolecular weight:592.11Acetoxycycloheximide
CAS:<p>Acetoxycycloheximide triggers TNF receptor 1, prompts apoptosis, and cytochrome c release by activating c-Jun N-terminal kinase.</p>Formula:C17H25NO6Color and Shape:SolidMolecular weight:339.38Meclocycline
CAS:<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formula:C22H21ClN2O8Color and Shape:SolidMolecular weight:476.86I-BET282E
<p>I-BET282E inhibits eight BET bromodomains (pIC50 6.4-7.7) with selectivity for other bromodomain proteins.</p>Formula:C26H34N4O7SColor and Shape:SolidMolecular weight:546.64SP4206
CAS:<p>SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)</p>Formula:C30H37Cl2N7O6Purity:98%Color and Shape:SolidMolecular weight:662.56PD-1/PD-L1-IN-17
<p>PD-1/PD-L1-IN-17 (Compound P20) is a potent PD-1/PD-L1 inhibitor (IC50: 26.8 nM).</p>Formula:C23H20ClN3O4Color and Shape:SolidMolecular weight:437.88MNK1/2-IN-6
<p>MNK1/2-IN-6: Strong, selective MNK1/2 inhibitor; IC50s: MNK1 at 2.3 nM, MNK2 at 3.4 nM; triggers dose-dependent apoptosis.</p>Formula:C27H24N6OColor and Shape:SolidMolecular weight:448.52MK-3402
CAS:<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Formula:C15H19N9O5S2Color and Shape:SolidMolecular weight:469.50OICR12694
CAS:<p>OICR12694 (JNJ-65234637) is an orally active inhibitor of B cell lymphoma 6 (BCL6) .</p>Formula:C29H28ClF3N8O4Color and Shape:SolidMolecular weight:645.03RORγt inverse agonist 29
<p>RORγt inverse agonist 29 is a potent, selective, orally active RORγt inverse agonist with an IC50 value of 21 nM.</p>Formula:C25H24N2O5SColor and Shape:SolidMolecular weight:464.53Uprosertib hydrochloride
CAS:<p>Uprosertib hydrochloride is a potent and selective inhibitor of pan-Akt (IC50: 180/328/38 nM for Akt1/Akt2/Akt3, respectively).</p>Formula:C18H17Cl3F2N4O2Purity:98%Color and Shape:SolidMolecular weight:465.719(S)-HETE
CAS:<p>9(S)-HETE is an enantiomer of (±)9-HETE, not an enzymatic product, and doesn't promote cell adhesion like 12(S)-HETE. Identified by chiral HPLC.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47Furaprevir
CAS:<p>Furaprevir is an HCV NS3/4A Inhibitor</p>Formula:C47H56N6O10SColor and Shape:SolidMolecular weight:897.05MT-134
<p>MT-134 is a SkMII -specific inhibitor and has excellent exposure in muscles.</p>Formula:C19H16N4O3Color and Shape:SolidMolecular weight:348.36AMG-315
CAS:<p>AMG-315: Chiral AEA analogue, potent CB1 agonist (Ki 7.8 nM, EC50 0.6 nM), stable against hydrolyzing/oxidative enzymes.</p>Formula:C24H41NO2Color and Shape:SolidMolecular weight:375.59MEK1/2-IN-2
<p>MEK1/2-IN-2 is a potent, ATP-competitive MEK1/2 inhibitor that exhibits equal inhibitory effects on wild-type MEK1/2 and a group of MEK1/2 mutant cells.</p>Formula:C28H22ClFN6OColor and Shape:SolidMolecular weight:512.97FtsZ-IN-4
<p>FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).</p>Formula:C21H16ClF2NO2Color and Shape:SolidMolecular weight:387.81RET-IN-14
CAS:<p>RET-IN-14 inhibits RET (IC50: <0.51-9.3 nM) & BTK (C481S) (IC50: 9.2-15 nM), promising for tumor research.</p>Formula:C24H23FN8O4Color and Shape:SolidMolecular weight:506.49GSK3527497 HCl
CAS:<p>GSK3527497: potent TRPV4 inhibitor, IC50=12 nM, targets heart/respiratory issues, for oral/IV use, low-dose effective.</p>Formula:C17H17Cl2FN4O4SColor and Shape:SolidMolecular weight:463.3054Cap-dependent endonuclease-IN-6
CAS:<p>Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.</p>Formula:C23H21N3O3SColor and Shape:SolidMolecular weight:419.5PKG1α activator 3
<p>PKG1α activator 3 is a PKG1α activator (EC50basal/partial=13/0.52 μM).</p>Formula:C27H26Cl2N2O6Color and Shape:SolidMolecular weight:545.41SGK1-IN-3
<p>SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.</p>Formula:C23H20Cl2N6O3SColor and Shape:SolidMolecular weight:531.41Mesulergine
CAS:<p>Mesulergine is metabolized into dopaminergic agonists.</p>Formula:C18H26N4O2SColor and Shape:SolidMolecular weight:362.49PD 136450
CAS:<p>PD-136,450: partial stomach secretory agonist, full pancreas agonist in rats; potential acid-reducing drug, adjuvant for gastrin-sensitive tumors.</p>Formula:C35H40N4O6Purity:98%Color and Shape:SolidMolecular weight:612.72DHU-Se1
<p>DHU-Se1: potent anti-inflammatory, releases reactive selenium from macrophages, inhibits iNOS/TNF-α, blocks M0 to M1 polarization.</p>Formula:C23H23N3OSSeColor and Shape:SolidMolecular weight:468.47SSTR5 antagonist 2 TFA
CAS:<p>Potent, oral SSTR5 antagonist 2 TFA may treat type 2 diabetes.</p>Formula:C34H36F4N2O7Purity:98%Color and Shape:SolidMolecular weight:660.65Ketomethylenebestatin
CAS:<p>Ketomethylenebestatin, a weaker carba-analog of aminopeptidase inhibitor bestatin, is 10x less potent.</p>Formula:C17H25NO4Purity:98%Color and Shape:SolidMolecular weight:307.38AN-12-H5
CAS:<p>AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.</p>Formula:C24H23N3O4S3Color and Shape:SolidMolecular weight:513.65Antibacterial agent 112
<p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>Formula:C35H23N5O5Color and Shape:SolidMolecular weight:593.59Dihydrokainic acid
CAS:<p>EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake</p>Formula:C10H17NO4Purity:98%Color and Shape:SolidMolecular weight:215.25CDK8-IN-11 hydrochloride
<p>CDK8-IN-11 HCl: potent, selective CDK8 inhibitor (IC50: 46 nM), blocks WNT/β-catenin pathway, used in colon cancer research.</p>Formula:C19H16ClF3N4O2Color and Shape:SolidMolecular weight:424.8Vanin-1-IN-3
<p>Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC 50 of 0.038 μM [1].</p>Formula:C17H22F3NO5Color and Shape:SolidMolecular weight:377.36COX-2-IN-13
<p>COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.</p>Formula:C19H18N2O5SColor and Shape:SolidMolecular weight:386.42AVE-1330A free acid
CAS:<p>AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor.</p>Formula:C7H11N3O6SColor and Shape:SolidMolecular weight:265.24E-3030 free acid
CAS:<p>E-3030 free acid, a PPAR agonist, lowers blood glucose, triglycerides, and insulin; boosts adiponectin; reduces apo C-III; and raises lipoprotein lipase.</p>Formula:C22H23ClFNO5Purity:98%Color and Shape:SolidMolecular weight:435.87Revamilast sodium
CAS:<p>Revamilast sodium, also known as GRC4039 sodium, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritis</p>Formula:C18H8Cl2F2N3NaO4Color and Shape:SolidMolecular weight:462.17Antitumor agent-43
<p>Antitumor agent-43 (Compound 4B) is a potent antitumor agent that induces cell cycle arrest at G2/M phase.</p>Formula:C16H8N2O3Color and Shape:SolidMolecular weight:276.25MRGPRX1 agonist 4
<p>Potent, oral MRGPRX1 agonist 4 modulates receptor positively (EC50: 0.1 μM) and reduces mice's thermal allergy response.</p>Formula:C23H17Cl2F3N2O2SColor and Shape:SolidMolecular weight:513.36RORγt modulator 5
CAS:<p>RORγt modulator 5, a potent RORγt modulator, exhibits a dissociation constant (K_i) of <100 nM.</p>Formula:C27H22F5N3O6SColor and Shape:SolidMolecular weight:611.54Lamivudine, (+/-)-trans-
CAS:<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Formula:C8H11N3O3SPurity:98%Color and Shape:SolidMolecular weight:229.26Mcl-1 inhibitor 9
CAS:<p>Mcl-1 Inhibitor 9 (Example 2) is a potent inhibitor of myeloid cell leukemia 1 (Mcl-1), demonstrating anti-tumor activity with an IC50 value of 0.21889 nM.</p>Formula:C32H39ClN2O5SColor and Shape:SolidMolecular weight:599.18Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Formula:C20H21Br2N5O4SPurity:98%Color and Shape:SolidMolecular weight:587.29PF-07054894
CAS:<p>PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.</p>Formula:C24H30N6O4Color and Shape:SolidMolecular weight:466.53PIKfyve-IN-1
<p>PIKfyve-IN-1: potent, cell-active inhibitor for PIKfyve research, IC50=6.9 nM.</p>Formula:C20H21N5Color and Shape:SolidMolecular weight:331.41SJG-136
CAS:<p>SJG-136 is a DNA cross-linking agent (XL50: 45 nM for pBR322 DNA).</p>Formula:C31H32N4O6Purity:98%Color and Shape:SolidMolecular weight:556.61Udifitimod
CAS:<p>Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.</p>Formula:C25H33NO2Color and Shape:SolidMolecular weight:379.54Colistin adjuvant-1
<p>Colistin adjuvant-1, inhibits NF-κB (IC50: 0.209 μM), boosts mucin against gram-negative bacteria.</p>Formula:C16H7F9N2OColor and Shape:SolidMolecular weight:414.23HIV-1 inhibitor-40
<p>HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.</p>Formula:C25H18N6O2Color and Shape:SolidMolecular weight:434.45KY-02327 acetate
<p>KY-02327 acetate inhibits Dvl-CXXC5, stabilizes Wnt/β-catenin signaling, and enhances osteoblast differentiation.</p>Formula:C22H31N3O6Color and Shape:SolidMolecular weight:433.5Geissoschizoline
CAS:<p>Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.</p>Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42Rafutrombopag
CAS:<p>Rafutrombopag is a thrombopoietin (TPO) agonist.</p>Formula:C25H22N4O5Color and Shape:SolidMolecular weight:458.47Plevitrexed
CAS:<p>Plevitrexed, an oral TS inhibitor (Ki: 0.44 nM), targets α-folate receptor & reduced folate carrier, treats gastric cancer.</p>Formula:C26H25FN8O4Purity:98%Color and Shape:SolidMolecular weight:532.53GRP78-IN-1
<p>GRP78-IN-1 binds to GRP78 protein, inhibits cell growth, and triggers apoptosis in breast cancer; has -8.07 kcal/mol binding energy.</p>Formula:C21H23FO3Color and Shape:SolidMolecular weight:342.4OP-5244
CAS:<p>OP-5244 has comparable potency to bisphosphonic acid series and targets CD73.</p>Formula:C19H29ClN5O9PPurity:98%Color and Shape:SolidMolecular weight:537.89CPX-351
CAS:<p>CPX-351 (Vyxeos) is a liposomal encapsulant of cytarabine and Zoerythromycin with potential antitumor activity.</p>Formula:C36H42N4O15Purity:98.95% - 99.763%Color and Shape:SolidMolecular weight:770.74PI3K-IN-37
CAS:<p>PI3K-IN-37 inhibits PI3K α/β/δ (IC50: 6/8/4 nM) and mTOR (IC50: 4 nM).</p>Formula:C25H26N6O2Color and Shape:SolidMolecular weight:442.51c-Met-IN-2
CAS:<p>c-Met-IN-2 is a selective and orally available c-Met inhibitor (IC50: 0.6 nM) with antitumor activity.</p>Formula:C24H21FN10OPurity:98%Color and Shape:SolidMolecular weight:484.49BACE1-IN-8
<p>BACE1-IN-8 is a potent inhibitor of BACE1 (β-site APP lyase 1) (IC50: 3.9 μM).</p>Formula:C29H45N5O7Color and Shape:SolidMolecular weight:575.7Lorajmine
CAS:<p>Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.</p>Formula:C22H27ClN2O3Purity:98%Color and Shape:SolidMolecular weight:402.91Galectin-3-IN-2
<p>Galectin-3-IN-2 inhibits galactose lectin-3 (Gal-3) with an 8.3 μM IC50, impacting cancer-related metabolism.</p>Formula:C24H30FN3O10SColor and Shape:SolidMolecular weight:571.57Galectin-8-IN-1
<p>Galectin-8-IN-1 selectively binds galectin-8N with 48 μM affinity, 15x more than galectin-3.</p>Formula:C16H18N2O6Color and Shape:SolidMolecular weight:334.32Fradafiban
CAS:<p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>Formula:C20H21N3O4Purity:98%Color and Shape:SolidMolecular weight:367.40PCSK9-IN-16
CAS:<p>PCSK9-IN-16, holds potential for research into hypercholesterolemia and other cardiovascular diseases [1].</p>Formula:C16H20N6O2S3Color and Shape:SolidMolecular weight:424.56RdRP-IN-4
<p>RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.</p>Formula:C17H17Br2N3O2Color and Shape:SolidMolecular weight:455.14DHFR-IN-4
CAS:<p>DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.</p>Formula:C18H21N5O2SPurity:99.41%Color and Shape:SolidMolecular weight:371.46MI-1481
CAS:<p>MI-1481: potent MML1 inhibitor, IC50 3.6 nM; disrupts menin-MLL1, active in MLL leukemia.</p>Formula:C29H30F3N7O2SPurity:98%Color and Shape:SolidMolecular weight:597.65HIF-2α-IN-5
CAS:<p>HIF-2α-IN-5 is a potent HIF-2α inhibitor with an IC 50 of < 50 nM [1].</p>Formula:C15H12F4O3S2Color and Shape:SolidMolecular weight:380.38DLK-IN-1
CAS:DLK-IN-1: Oral DLK (MAP3K12) inhibitor, Ki=3nM, effective in Alzheimer's model, CNS permeable, well-tolerated with sustained brain levels.Formula:C20H24F3N5O2Color and Shape:SolidMolecular weight:423.43di-Val-L-dC
CAS:<p>Di-Val-L-dC, a reverse transcriptase inhibitor, is used potentially for treatment of HBV infection.</p>Formula:C19H31N5O6Purity:98%Color and Shape:SolidMolecular weight:425.48Isoleucyl tRNA synthetase-IN-2
CAS:<p>Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).</p>Formula:C22H33N5O8SColor and Shape:SolidMolecular weight:527.5916(R)-Iloprost
CAS:<p>Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).</p>Formula:C22H32O4Color and Shape:SolidMolecular weight:360.49GPX4-IN-3
CAS:<p>GPX4-IN-3 (26a) is a potent GPX4 inhibitor, inducing selective ferroptosis with 71.7% inhibition at 1 μM.</p>Formula:C29H24ClN3O3SColor and Shape:SolidMolecular weight:530.04CDK9-IN-11
CAS:<p>CDK9-IN-11 is a potent CDK9 inhibitor that is the ligand for the PROTAC CDK9 Degrader-1 [1].</p>Formula:C20H25N3O4Purity:98%Color and Shape:SolidMolecular weight:371.43PARP-1-IN-1
<p>PARP-1-IN-1: Selective, oral PARP-1 inhibitor with 0.96 nM IC50; well-tolerated and effective in single-dose MDA-MB-436 model.</p>Formula:C23H25FN4OColor and Shape:SolidMolecular weight:392.47Azonafide-PEABA
CAS:<p>Azonafide-PEABA is a drug moiety with cytotoxic [1].</p>Formula:C32H33N5O4Purity:98%Color and Shape:SolidMolecular weight:551.64TDI-11861
CAS:<p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>Formula:C22H25ClF2N6O3Color and Shape:SolidMolecular weight:494.92SC13
CAS:<p>SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.</p>Formula:C26H30N2O5Color and Shape:SolidMolecular weight:450.53Antifungal agent 28
<p>Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.</p>Formula:C22H29N5OSColor and Shape:SolidMolecular weight:411.56
