Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,524 products)
- Apoptosis(5,793 products)
- Cell Cycle/Checkpoint(4,452 products)
- Chromatin/Epigenetics(2,242 products)
- Cytoskeletal Signaling(1,382 products)
- DNA Damage/DNA Repair(2,826 products)
- Endocrinology/Hormones(3,507 products)
- Enzyme(3,640 products)
- GPCR/G-Protein(8,333 products)
- Immunology and Inflammation(3,527 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(404 products)
- MAPK Signaling(1,203 products)
- Membrane Transporter/Ion Channel(2,792 products)
- Metabolism(9,449 products)
- Microbiology/Virology(6,981 products)
- Neuroscience(9,926 products)
- Other Inhibitors(37,921 products)
- Oxidation-Reduction(41 products)
- PI3K/Akt/mTOR Signaling(1,400 products)
- Proteases/Proteasome(1,597 products)
- Stem Cell and Derivatives(830 products)
- Tyrosine Kinase/Adaptors(2,015 products)
- Ubiquitination(1,650 products)
Show 16 more subcategories
Found 66639 products of "Inhibitors"
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MM-589
CAS:<p>MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.</p>Formula:C28H44N8O5Purity:98%Color and Shape:SolidMolecular weight:572.70CDK1-IN-3
<p>CDK1-IN-3 is a selective inhibitor targeting CDK1 (36.8 nM), CDK2 (305.17 nM), CDK5 (369.37 nM); used in cancer research.</p>Formula:C28H25ClF3N5O2Color and Shape:SolidMolecular weight:555.98Oncopterin
CAS:<p>Oncopterin is found in urine from patients with solid and blood cancers.</p>Formula:C12H18N6O3Color and Shape:SolidMolecular weight:294.31YW3-56 (hydrochloride) (technical grade)
CAS:<p>YW3-56: PAD2 & PAD4 inhibitor (IC50 = 0.5-5 μM), halts U2OS cell growth (IC50 ~2.5 μM), reduces S-180 & MDA-MB-231 tumor growth in mice.</p>Formula:C27H33Cl2N5O2Color and Shape:SolidMolecular weight:530.49GnRH-R antagonist 1
CAS:<p>Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.</p>Formula:C31H28F5N7O6SPurity:98%Color and Shape:SolidMolecular weight:721.65IL-17 modulator 5
CAS:<p>IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM .</p>Formula:C28H23F6N9O2Color and Shape:SolidMolecular weight:631.53S1PR1 agonist 2
CAS:<p>S1PR1 agonist 2 is potent for autoimmune research (from WO2021175225A1).</p>Formula:C25H25N5O4Color and Shape:SolidMolecular weight:459.50GPX4-IN-3
CAS:<p>GPX4-IN-3 (26a) is a potent GPX4 inhibitor, inducing selective ferroptosis with 71.7% inhibition at 1 μM.</p>Formula:C29H24ClN3O3SColor and Shape:SolidMolecular weight:530.04Cap-dependent endonuclease-IN-14
CAS:<p>Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).</p>Formula:C30H23FN2O6SColor and Shape:SolidMolecular weight:558.58Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formula:C31H44N2O6SColor and Shape:SolidMolecular weight:572.76LPM4870108
<p>LPM4870108: Potent, oral pan-Trk inhibitor, selective over ALK, with anti-tumor effects. TrkC IC50=0.2nM, TrkA IC50=2.4nM.</p>Formula:C20H19FN6O3Color and Shape:SolidMolecular weight:410.4Vindeburnol
CAS:<p>Vindeburnol is a cerebral vasodilator vincamine analog that bears neuroprotective properties.</p>Formula:C17H20N2OColor and Shape:SolidMolecular weight:268.35Gln-AMS TFA
<p>Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.</p>Formula:C17H23F3N8O10SColor and Shape:SolidMolecular weight:588.47FLT3-IN-13
<p>FLT3-IN-13 inhibits topoisomerase II/FLT3 in leukemia with IC50 of 2.26 μM, causes G2/M arrest, and promotes apoptosis.</p>Formula:C20H14N4O2Color and Shape:SolidMolecular weight:342.35PCSK9-IN-16
CAS:<p>PCSK9-IN-16, holds potential for research into hypercholesterolemia and other cardiovascular diseases [1].</p>Formula:C16H20N6O2S3Color and Shape:SolidMolecular weight:424.56Cap-dependent endonuclease-IN-25
CAS:<p>Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)</p>Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48KCL-440
CAS:<p>RS 57639 is a bioactive chemical.</p>Formula:C18H18N2O2Color and Shape:SolidMolecular weight:294.35BAA473
<p>BAA473, a bile acid analog, activates the pyrin inflammasome, triggering IL-18 secretion in myeloid and intestinal cells.</p>Formula:C36H62O5Purity:98%Color and Shape:SolidMolecular weight:574.87FXIa-6f
CAS:<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Formula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04Dyrk1A-IN-4
CAS:<p>Dyrk1A-IN-4, compound 48, is an oral DYRK1A/DYRK2 inhibitor with IC50s: 2 nM (DYRK1A), 6 nM (DYRK2), anticancer properties.</p>Formula:C14H13F3N6Color and Shape:SolidMolecular weight:322.29MraY-IN-2
<p>MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.</p>Formula:C16H23N3O9Color and Shape:SolidMolecular weight:401.37PDE-I2
CAS:<p>PDE-I2 is a parasite schizogony inhibitor.</p>Formula:C25H23N5O8Color and Shape:SolidMolecular weight:521.48CCR1 antagonist 11 hydrochloride
<p>Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.</p>Color and Shape:SolidAD5075
CAS:<p>AD5075 is a bioactive chemical.</p>Formula:C22H20N2O5SColor and Shape:SolidMolecular weight:424.47Sequoiaflavone
CAS:<p>Sequoiaflavone is a biflavone isolated from Ginkgo biloba.</p>Formula:C31H20O10Color and Shape:SolidMolecular weight:552.48NK-1 Antagonist 1
CAS:<p>NK-1 Antagonist 1 is a NK-1 receptor antagonist.</p>Formula:C25H23F6N5O2Purity:98%Color and Shape:SolidMolecular weight:539.47AChE/BChE-IN-3 hydrochloride
<p>AChE/BChE-IN-3 (BMC-1) HCl is a dual inhibitor with IC50s: eqBChE 0.383 μM, elAChE 6.08 μM.</p>Formula:C15H25ClN2O3Color and Shape:SolidMolecular weight:316.82ZK168281
CAS:<p>ZK168281 is a 1α,25(OH)2D3 analog, VDR antagonist with 0.1 nM Kd, and blocks receptor CoA interaction.</p>Formula:C32H46O5Purity:98%Color and Shape:SolidMolecular weight:510.70Vulolisib
CAS:<p>Vulolisib inhibits PI3K (α: IC50 0.2nM, β: 168nM, γ: 90nM, δ: 49nM), taken orally with anti-cancer properties.</p>Formula:C18H19F2N5O3SColor and Shape:SolidMolecular weight:423.44AM-9514
CAS:<p>AM-9514: a potent Glucokinase activator with strong in vitro results, good pharmacokinetics, and efficacy in diabetes.</p>Formula:C18H25N5O4Color and Shape:SolidMolecular weight:375.42PARP10/15-IN-2
CAS:<p>PARP10/15-IN-2 (Compound 8h) blocks PARP10/15, has IC50s: 0.15μM/0.37μM, cell-permeable, prevents apoptosis.</p>Formula:C15H11FN2O3Color and Shape:SolidMolecular weight:286.26Anticancer agent 62
CAS:<p>Anticancer agent 62 inhibits HepG2, Bel-7402, MCF-7 growth with IC50: 0.019, 0.060, 0.016 μM respectively, and halts tumors.</p>Formula:C20H19ClN3Na2O8PSColor and Shape:SolidMolecular weight:573.85GL0388
<p>GL0388, a Bax activator, induces apoptosis, hinders breast cancer growth, and has IC50 of 0.299-1.57 μM.</p>Formula:C21H17FN2OColor and Shape:SolidMolecular weight:332.37CXCR4 probe 1
CAS:<p>CXCR4 probe 1, a specific PET tracer, targets CXCR4 with antagonist TN14003 (IC50: 6.9 nM), aiding in imaging CXCR4-related diseases and tumors.</p>Formula:C24H30FN5O4SColor and Shape:SolidMolecular weight:502.59G-479
CAS:<p>G-479, a potent MEK inhibitor and improved analogue of GDC-0623, has distributed polarity enhancing bioactivity.</p>Formula:C16H15FIN5O4Color and Shape:SolidMolecular weight:487.22CDK7/12-IN-1
CAS:<p>CDK7/12-IN-1 is a selective CDK7 (IC50: 3 nM) and CDK12 (IC50: 277 nM) inhibitor, effective against tumor growth.</p>Formula:C25H34N8OColor and Shape:SolidMolecular weight:462.59MAFP
CAS:<p>MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase.</p>Formula:C21H36FO2PColor and Shape:SolidMolecular weight:370.48FGFR1 inhibitor-6
<p>FGFR1 inhibitor-6, IC50: 16.31 nM, blocks cell cycle at pro-G1/G2/M and induces apoptosis.</p>Formula:C27H19N5O4S2Color and Shape:SolidMolecular weight:541.6CXCR2 antagonist 5
<p>CXCR2 antagonist 5 (compound 25) binds strongly (IC50=0.013μM) and mobilizes calcium (IC50=0.1μM).</p>Formula:C15H14F2N4O2SColor and Shape:SolidMolecular weight:352.36E 5090
CAS:<p>E5090 is a novel orally active inhibitor of IL-1 generation. It also has anti-inflammatory properties.</p>Formula:C19H20O5Purity:98%Color and Shape:SolidMolecular weight:328.36STA-1474
CAS:<p>STA-1474, a soluble prodrug of ganetespib (STA-9090), becomes a strong HSP90 inhibitor effective against canine tumors.</p>Formula:C20H21N4O6PColor and Shape:SolidMolecular weight:444.38COX-2-IN-12
<p>COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.</p>Formula:C17H19NO3Color and Shape:SolidMolecular weight:285.34Porphobilinogen
CAS:<p>Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.</p>Formula:C10H14N2O4Purity:98%Color and Shape:SolidMolecular weight:226.23Suloctidil HCl
CAS:<p>Suloctidil HCl is a peripheral vascular dilator.</p>Formula:C20H36ClNOSColor and Shape:SolidMolecular weight:374.02KRAS G12D inhibitor 9
CAS:<p>KRAS G12D inhibitor 9 targets RAS protein, key in growth, showing promise against KRAS G12D cancer.</p>Formula:C33H43N7O2Color and Shape:SolidMolecular weight:569.74HIV-1 inhibitor-44
<p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>Formula:C23H26N2O4SColor and Shape:SolidMolecular weight:426.53SHP2 IN-1
CAS:<p>SHP2 IN-1 is an allergic SHP2 (PTPN11) inhibitor(IC50 : 3 nM).</p>Formula:C18H22Cl2N6OSPurity:98%Color and Shape:SolidMolecular weight:441.38HDAC6-IN-9
CAS:<p>HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.</p>Formula:C19H16N2O3Purity:98.84%Color and Shape:SolidMolecular weight:320.34VRT-18858
CAS:<p>VRT-18858 is a metabolite of VX-740.</p>Formula:C24H25N5O7Color and Shape:SolidMolecular weight:495.48Nepaprazole sodium
CAS:<p>Nepaprazole Na (TY-11345), a proton pump inhibitor, may treat gastric ulcers; it reduces H+/K(+)-ATPase activity, with IC50 of 5.8-9.9 microM.</p>Formula:C18H18N3NaO2SColor and Shape:SolidMolecular weight:363.41R-96544 hydrochloride
CAS:<p>5-HT2 receptor antagonist</p>Formula:C22H29NO3Purity:98%Color and Shape:SolidMolecular weight:355.47SCP1-IN-1
CAS:<p>SCP1-IN-1 (SH T-62) is a potent inhibitor of SCP1, promoting REST degradation and potentially aiding glioblastoma research.</p>Formula:C20H19F3N2O7S2Purity:99.53%Color and Shape:SoildMolecular weight:520.5Lavendomycin
CAS:<p>Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.</p>Formula:C29H50N10O8Color and Shape:SolidMolecular weight:666.77KRAS G12C inhibitor 20
CAS:<p>KRAS G12C inhibitor 20 is a KRAS G12C inhibitor.</p>Formula:C33H37ClFN7O3Color and Shape:SolidMolecular weight:634.14PDHK-IN-3
<p>PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].</p>Formula:C17H16N2O2Color and Shape:SolidMolecular weight:280.32NS2B/NS3-IN-2
<p>Potent dengue inhibitor NS2B/NS3-IN-2 (IC50: 6 nM, Ki: 0.66 μM) boosts cell viability, non-toxic.</p>Formula:C24H21N3O5SColor and Shape:SolidMolecular weight:463.51ICA-105665
CAS:<p>ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.</p>Formula:C19H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:355.34Asukamycin
CAS:<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Formula:C31H34N2O7Color and Shape:SolidMolecular weight:546.61CP-481715
CAS:<p>CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.</p>Formula:C26H31FN4O4Color and Shape:SolidMolecular weight:482.55Saprisartan potassium
CAS:<p>Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.</p>Formula:C25H21BrF3KN4O4SColor and Shape:SolidMolecular weight:649.52Topoisomerase II inhibitor 6
<p>Topoisomerase II inhibitor 6, a potent tryptanthrin derivative, blocks G2 phase in CCRF-CEM cells, induces DNA breaks, and may be used for cancer research.</p>Formula:C19H18N4O2Color and Shape:SolidMolecular weight:334.37TGR5 Receptor Agonist 3
CAS:<p>TGR5 Receptor Agonist 3 is a GPBAR1 agonist with EC50 of 16.4 nM (hTGR5) & 209 nM (mTGR5), ensures gallbladder safety and reduces filling.</p>Formula:C29H27N3O6Color and Shape:SolidMolecular weight:513.54RIPK1-IN-14
CAS:<p>RIPK1-IN-14 inhibits RIPK1 with 92 nM IC50 and reduces necrotic apoptosis in U937 cells.</p>Color and Shape:SoildVEGFR2-IN-1
CAS:<p>VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.</p>Formula:C22H18N6SPurity:98.15%Color and Shape:SolidMolecular weight:398.48Antitumor agent-47
<p>Antitumor agent-47, a silibinin derivative, shows cytotoxicity in NCI-H1299 (IC50: 8.07µM) and HT29 (IC50: 6.27µM) cells.</p>Formula:C30H27NO11Color and Shape:SolidMolecular weight:577.54ND-654
CAS:<p>ND-654 is an acetyl CoA carboxylase inhibitor.</p>Formula:C29H33N3O8SColor and Shape:SolidMolecular weight:583.65Trichostatin A S-isomer
CAS:<p>Trichostatin A S-isomer, a HDAC 1, 3, 4, 6, 10 inhibitor with IC50 ~20 nM, has wide-ranging epigenetic effects.</p>Formula:C17H22N2O3Purity:98%Color and Shape:SolidMolecular weight:302.37Icariside F2
CAS:<p>Icariside F2 modestly inhibits α-glucosidase (4.6-12%) and has antioxidant properties, plus strong NF-κB inhibition (IC50: 16.25±2.19 μM).</p>Formula:C18H26O10Purity:98%Color and Shape:SolidMolecular weight:402.39INCB-9471 dihydrochloride
CAS:<p>INCB-9471 HCl: a potent CCR5 antagonist, blocks monocyte migration & HIV-1.</p>Formula:C30H42Cl2F3N5O2Purity:98%Color and Shape:SolidMolecular weight:632.59Antibiotic MA 144M2
CAS:<p>Antibiotic MA 144M2, an anthracycline glycoside, targets gram-positive bacteria and tumors, derived from Streptomyces and aclacinomycin A conversion.</p>Formula:C42H55NO16Color and Shape:SolidMolecular weight:829.88Emtricitabine triphosphate
CAS:<p>Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.</p>Formula:C8H13FN3O12P3SColor and Shape:SolidMolecular weight:487.19PI3Kα-IN-8
<p>PI3Kα-IN-8 is a selective inhibitor of PI3Kα (IC50: 0.012 μM).</p>Formula:C26H27BrN4O2Color and Shape:SolidMolecular weight:507.42Gamendazole
CAS:<p>Gamendazole is a novel drug candidate for male contraception. It has been shown to reduce fertility in male rats without affecting testosterone levels.</p>Formula:C18H11Cl2F3N2O2Purity:98%Color and Shape:SolidMolecular weight:415.19hA3AR agonist 1
<p>hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .</p>Formula:C10H14N6OSColor and Shape:SolidMolecular weight:266.32(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formula:C14H10ClN3S2Color and Shape:SolidMolecular weight:319.83MB725
CAS:<p>MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.</p>Formula:C18H21IN4O2SColor and Shape:SolidMolecular weight:484.35Sesamodil
CAS:<p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>Formula:C29H32N2O6SPurity:98.58% - 99.01%Color and Shape:SolidMolecular weight:536.64CI-1029
CAS:<p>CI-1029: HIV protease inhibitor, combats mutant strains, high efficacy, good bioavailability in animals.</p>Formula:C28H37NO4SColor and Shape:SolidMolecular weight:483.66S-1033
CAS:<p>S-1033 is an FP receptor agonist.</p>Formula:C20H33NaO4Color and Shape:SolidMolecular weight:360.4698Uprosertib hydrochloride
CAS:<p>Uprosertib hydrochloride is a potent and selective inhibitor of pan-Akt (IC50: 180/328/38 nM for Akt1/Akt2/Akt3, respectively).</p>Formula:C18H17Cl3F2N4O2Purity:98%Color and Shape:SolidMolecular weight:465.71NNC-11-1585
CAS:<p>NNC-11-1585 is an M(1) and M(2) muscarinic acetylcholine receptor (mAChR) agonist.</p>Formula:C18H19N3OSColor and Shape:SolidMolecular weight:325.43PF-06305591 dihydrate
<p>PF-06305591 dihydrate is a potent and highly selective voltage gated sodium channel NaV1.8 blocker (IC 50 = 15 nM) with an excellent preclinical in vitro ADME</p>Formula:C15H26N4O3Color and Shape:SolidMolecular weight:310.39FXIa-IN-9
CAS:<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Formula:C23H18Cl2F3N9O2Color and Shape:SolidMolecular weight:580.35AMG-222 tosylate
CAS:<p>AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.</p>Formula:C39H47N9O6SColor and Shape:SolidMolecular weight:769.91GW-597901 cinnamate
CAS:<p>GW-597901 cinnamate is a long-acting beta(2)-agonist.</p>Formula:C34H46N2O8SColor and Shape:SolidMolecular weight:642.80Anti-Aβ agent 1A
<p>Anti-Aβ agent 1A is a potent anti-amyloid-β agent.</p>Formula:C35H49NO4Color and Shape:SolidMolecular weight:547.77AM-3189
CAS:<p>AM-3189: potent, selective GPR40 agonist with low CNS penetration, good pharmacokinetics, and efficacy mirroring AMG 837.</p>Formula:C27H25ClN2O3Color and Shape:SolidMolecular weight:460.95Pelecopan
CAS:<p>Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).</p>Formula:C23H19FN2O4Color and Shape:SolidMolecular weight:406.41NB-533
CAS:<p>NB-533 is a macrocyclic peptidic BACE-1 inhibitor.</p>Formula:C33H55N3O4Color and Shape:SolidMolecular weight:557.81Sucistil
<p>Sucistil is an active biochemical. hemoglobin sucistil (bovine) is an oxygen carrier [1].</p>Formula:C9H15NO4SColor and Shape:SolidMolecular weight:233.28rel-MDM2/4-p53-IN-2
<p>Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.</p>Formula:C25H17Cl3FN3O3Color and Shape:SolidMolecular weight:532.78NF-κB-IN-4
<p>NF-κB-IN-4 (compound 17) is a potent inhibitor of NF-κB pathway which can cross blood brain barrier (BBB).</p>Formula:C18H15FN4OColor and Shape:SolidMolecular weight:322.34RhlR antagonist 1
<p>RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.</p>Formula:C12H10F2OColor and Shape:SolidMolecular weight:208.2IDO1-IN-13
<p>IDO1-IN-13 is a potent IDO1 inhibitor (IC50: 61.6 nM, EC50: 30 nM in HeLa) that reduces kyn/trp ratio by 51% in SK-OV-3 tumors.</p>Formula:C20H16BrN5O2SColor and Shape:SolidMolecular weight:470.34JBJ-02-112-05
CAS:<p>JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC 50 of 15 nM for EGFR L858R/T790M [1].</p>Formula:C27H20N4O2SPurity:98%Color and Shape:SolidMolecular weight:464.54Alkyne-probe 1
<p>Alkyne-probe 1 is usually used as an Alkyne-labeled fluorescent or chemical probe.</p>Formula:C14H23N5O2Purity:98%Color and Shape:SolidMolecular weight:293.36Dinordrin I diacetate
CAS:<p>Dinordrin I diacetate is an implantation inhibitor and hormone.</p>Formula:C25H32O4Purity:98%Color and Shape:SolidMolecular weight:396.52O4
CAS:<p>O4 is a novel stabilizer of amyloid- fibrils. O4 used for accelerating the formation of end-stage mature fibrils.</p>Formula:C24H15NO7Purity:98%Color and Shape:SolidMolecular weight:429.38HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formula:C29H32N6O4SColor and Shape:SolidMolecular weight:560.67CI 922
CAS:<p>CI 922 is an anaphylaxis mediator release inhibitor. It inhibits the activation of human neutrophils.</p>Formula:C26H30N10O6Color and Shape:SolidMolecular weight:578.58GSK864
CAS:<p>GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).</p>Formula:C30H31FN6O4Purity:97.07%Color and Shape:SolidMolecular weight:558.6Quorum Sensing-IN-1
<p>Quorum Sensing-IN-1 is a small-molecule inhibitor of quorum sensing.</p>Formula:C13H10N2O2S2Color and Shape:SolidMolecular weight:290.36NLRP3-IN-6
<p>NLRP3-IN-6 (Compound 34) is a selective inhibitor of the NLRP3 inflammasome.</p>Formula:C18H15ClN2O4S3Color and Shape:SolidMolecular weight:454.97(Rac)-PT2399
CAS:<p>(Rac)-PT2399 is a potent and specific inhibitor of hypoxia-inducible factor 2a (HIF-2α)(IC50 of 0.01 μM).</p>Formula:C17H10F5NO4SColor and Shape:SolidMolecular weight:419.32L5-DA
<p>L5-DA, a G-quadruplex ligand, stabilizes G4s in HeLa cells, induces apoptosis, and is cytotoxic with an IC50 of 4.3 μM.</p>Formula:C32H34N6O2Color and Shape:SolidMolecular weight:534.65PD-1-IN-17 TFA
<p>PD-1-IN-17 TFA is a potent PD-1 inhibitor, blocking 92% of splenocyte growth at 100 nM.</p>Formula:C15H23F3N6O9Color and Shape:SolidMolecular weight:488.37Anti-inflammatory agent 6
<p>Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.</p>Formula:C22H20O12Color and Shape:SolidMolecular weight:476.39OPC-167832
CAS:<p>OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.</p>Formula:C21H20ClF3N2O4Color and Shape:SolidMolecular weight:456.84PI3K-IN-35
CAS:<p>PI3K-IN-35 (6l) selectively inhibits PI3K-α, β, δ (IC50: 13.98, 7.22, 10.94 μM), blocks G2/M phase, induces apoptosis, and is useful in leukemia research.</p>Formula:C25H23N7O2Color and Shape:SolidMolecular weight:453.5COX-2-IN-8
<p>COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.</p>Formula:C19H19N3O4S2Color and Shape:SolidMolecular weight:417.5Rpi 856 C
CAS:<p>Rpi 856 C is a retrovirus protease inhibitor from Streptomyces that is effective against HIV-1 and HTLV-1 proteases.</p>Formula:C39H56N6O10Purity:98%Color and Shape:SolidMolecular weight:768.90KPH2f
CAS:<p>KPH2f: dual URAT1/GLUT9 inhibitor, orally active, IC50: 0.24μM (URAT1), 9.37μM (GLUT9), minimal OAT1/ABCG2 impact.</p>Formula:C24H16N3NaO2SColor and Shape:SolidMolecular weight:433.46COX-2/NO-IN-1
<p>COX-2/NO-IN-1: oral iNOS & NO blocker (IC50=3.52μM), COX-2 supressor, anti-inflammatory, protects kidneys.</p>Formula:C15H15NO3Color and Shape:SolidMolecular weight:257.28SSR 146977
CAS:<p>NK3 receptor antagonist</p>Formula:C35H42Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:621.64EB-0156
<p>EB-0156: potent ER α-glucosidase inhibitor, IC50 of 0.0479/ <0.001 μM, N-substituted valerian, broad-spectrum antiviral potential.</p>Formula:C21H32N6O7Color and Shape:SolidMolecular weight:480.51PF-06263276
CAS:<p>PF-06263276 selectively inhibits pan-JAK with IC50: JAK1 (2.2 nM), JAK2 (23.1 nM), JAK3 (59.9 nM), TYK2 (29.7 nM).</p>Formula:C31H31FN8O2Purity:98%Color and Shape:SolidMolecular weight:566.63LMD-A
CAS:<p>LMD-A, also known as CCR8 antagonist LMD-A, is a CCR8 antagonist.</p>Formula:C27H32N4O4SColor and Shape:SolidMolecular weight:508.63Mu opioid receptor antagonist 4
<p>Compound 31: Potent, selective MOR antagonist; crosses blood-brain barrier; Ki & EC50: 0.38 nM; useful for OUD research.</p>Formula:C25H28N2O4SColor and Shape:SolidMolecular weight:452.57MRGPRX1 agonist 3
<p>Compound 1f, a potent MRGPRX1 agonist, has an EC50 of 0.22 μM, useful for neuropathic pain studies.</p>Formula:C14H11FN2OSColor and Shape:SolidMolecular weight:274.31hCA IX-IN-1
<p>hCA IX-IN-1 inhibits human carbonic anhydrases I, II, IX, and XII with Ki values of 331.4, 28.4, 9.4, 17.8 nM and exhibits anticancer properties.</p>Formula:C19H18N2O3SColor and Shape:SolidMolecular weight:354.42LRRK2-IN-3
CAS:<p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>Formula:C25H29ClF2N6O2Color and Shape:SolidMolecular weight:518.99E7090 succinate
CAS:<p>E7090 succinate inhibits FGFR1, FGFR2, and FGFR3 with IC50: 0.71, 0.50, 1.2 nM; less so FGFR4 at 120 nM.</p>Formula:C76H92N10O24Color and Shape:SolidMolecular weight:1529.60COX-2-IN-29
<p>COX-2-IN-29 is a selective inhibitor of orally active COX-2 (IC50: 0.005 μM).</p>Formula:C22H23FN2O6S2Color and Shape:SolidMolecular weight:494.56SGLT1/2-IN-1
CAS:<p>SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.</p>Formula:C25H28O8Color and Shape:SolidMolecular weight:456.48Antibacterial agent 81
CAS:<p>Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.</p>Formula:C33H28N2O8Color and Shape:SolidMolecular weight:580.58Tubulin polymerization-IN-6
<p>Compound 5f, a potent tubulin polymerization inhibitor (IC50 = 1.09 μM), blocks cell migration, tube formation, and has anti-angiogenic effects.</p>Formula:C19H21NO7Color and Shape:SolidMolecular weight:375.37Chitin synthase inhibitor 5
<p>Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.</p>Formula:C23H22BrN3O5Color and Shape:SolidMolecular weight:500.34EGFR-IN-48
<p>EGFR-IN-48: potent EGFR inhibitor, oral, IC50: 0.193-66.7 nM, blocks EGFR mutants & BaF3/PC-9 cell proliferation.</p>Color and Shape:SolidHIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Formula:C21H32ClN7O3Color and Shape:SolidMolecular weight:465.98Napsagatran hydrate
CAS:<p>Napsagatran hydrate is a novel and specific inhibitor of thrombin.</p>Formula:C26H36N6O7SPurity:98%Color and Shape:SolidMolecular weight:576.66SP4206
CAS:<p>SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)</p>Formula:C30H37Cl2N7O6Purity:98%Color and Shape:SolidMolecular weight:662.56PF-446687
CAS:<p>PF-446687 is a highly selective MC4 receptor (MC4R) agonist.</p>Formula:C28H37ClF2N2O2Color and Shape:SolidMolecular weight:507.06Cilazapril HCl
CAS:<p>Cilazapril, also known as Ro 31 2848, is a potent ACE inhibitor used for hypertension.</p>Formula:C22H32ClN3O5Color and Shape:SolidMolecular weight:453.96Carnostatine
<p>Carnostatine (SAN9812), a potent CN1 inhibitor with 11 nM K i, may boost renal carnosine to treat DN.</p>Formula:C10H16N4O4Purity:98%Color and Shape:SolidMolecular weight:256.26SDM25N hydrochloride
CAS:<p>δ receptor antagonist</p>Formula:C26H27ClN2O3Purity:98%Color and Shape:SolidMolecular weight:450.96Tubulin polymerization-IN-33
<p>Tubulin-IN-33, an oxazoloisoindole, hinders microtubule assembly; effective against NCI cancer cells.</p>Formula:C27H28N2O6Color and Shape:SolidMolecular weight:476.52KDOAM-25 trihydrochloride
<p>KDOAM-25 trihydrochloride selectively inhibits KDM5 enzymes, boosts H3K4 methylation, and suppresses MM1S cell growth.</p>Formula:C15H28Cl3N5O2Color and Shape:SolidMolecular weight:416.77Antibiotic LL Z1640-2
CAS:<p>Antibiotic LL Z1640-2 is an inhibitor against the TAK1 activity.</p>Formula:C19H22O7Color and Shape:SolidMolecular weight:362.38K203
<p>K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.</p>Formula:C16H18Br2N4O2Color and Shape:SolidMolecular weight:458.15GSK1820795A
CAS:<p>GSK1820795A: Telmisartan analog, selective hGPR132a antagonist, blocks yeast activation by N-acylamides, angiotensin II antagonist, partial PPARγ agonist.</p>Formula:C35H34N8Color and Shape:SolidMolecular weight:566.7LLS30
CAS:<p>LLS30 inhibits Gal-1, reduces its binding affinity, and may help treat advanced prostate cancer.</p>Formula:C34H33Cl4N5O3Color and Shape:SolidMolecular weight:701.47BM635 mesylate
<p>BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.</p>Formula:C26H33FN2O4SColor and Shape:SolidMolecular weight:488.61Triciferol
CAS:<p>Triciferol is a VDR agonist and HDAC antagonist with 1,25D-like potency, affecting gene targets and tubulin, and shows anti-cancer effects in vitro. IC50=87nM.</p>Formula:C26H39NO4Color and Shape:SolidMolecular weight:429.591TAM&Met-IN-1
CAS:<p>TAM&Met-IN-1 inhibits AXL, MER, TYRO3 with IC50s 6.1, 13.2, 21.6 nM, respectively, for cancer research.</p>Formula:C29H27F2N7O5Color and Shape:SolidMolecular weight:591.57L-690330 hydrate
<p>L-690330 hydrate inhibits IMPase; Ki: 0.30 μM (human), 0.42 μM (bovine cortex); 0.27 μM (recom. human), 0.19 μM (bovine).</p>Formula:C8H14O9P2Color and Shape:SolidMolecular weight:316.14Acetomycin
CAS:<p>Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.</p>Formula:C10H14O5Color and Shape:SolidMolecular weight:214.22ONO-AE1-259 lysine
CAS:<p>ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)</p>Formula:C28H49ClN2O6Color and Shape:SolidMolecular weight:545.15(R)-FL118
CAS:<p>FL118 inhibits human survivinion expression and activates tumor suppressor p53 as a MOA in p53 wild-type cancer cells.</p>Formula:C21H16N2O6Color and Shape:SolidMolecular weight:392.36OICR-9429-N-C2-NH2
CAS:<p>OICR-9429-N-C2-NH2, a ligand for WDR5, intermediate 2, serves as a crucial compound in the synthesis of PROTACs.</p>Formula:C31H38F3N7O2Color and Shape:SolidMolecular weight:597.687cSPM
<p>cSPM (Cyclic spermine) is an Aβ42 inhibitor. cSPM inhibits the aggregation of three different peptides, Aβ42, tryptophan and insulin, and reduces cytotoxicity.</p>Formula:C27H57N7Color and Shape:SolidMolecular weight:479.79PARP10/15-IN-3
<p>Compound 8a, a dual PARP10 & PARP15 inhibitor, has IC50s: PARP10 at 0.14μM & PARP15 at 0.40μM; it's cell-permeable & anti-apoptotic.</p>Formula:C12H12N2O3Color and Shape:SolidMolecular weight:232.24ddCTP trisodium
<p>ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.</p>Formula:C9H13N3Na3O12P3Color and Shape:SolidMolecular weight:517.1Eprociclovir Na
CAS:<p>Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.</p>Formula:C11H14N5NaO3Color and Shape:SolidMolecular weight:287.25GC 14
CAS:<p>GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 200 nM and 35 nM for hTRα and hTRβ, respectively.</p>Formula:C26H27NO6Purity:98%Color and Shape:SolidMolecular weight:449.5(RS)-AMPA monohydrate
CAS:<p>(RS)-AMPA monohydrate, potent glutamate analogue, selectively activates L-glutamic acid without affecting kainic acid or NMDA receptors.</p>Formula:C7H12N2O5Color and Shape:SolidMolecular weight:204.182SLC4101431
<p>SLC4101431 is a potent SphK2 inhibitor with Ki value of 90 nM.</p>Formula:C29H28ClN7OSColor and Shape:SolidMolecular weight:558.1NLRP3-IN-8
CAS:<p>NLRP3-IN-8, orally active inflammasome blocker, IC50 of 1.23μM, stable (t1/2 = 138.63min), non-toxic (IC50 >100μM).</p>Formula:C23H20N2O6Color and Shape:SolidMolecular weight:420.41Anticancer agent 45
<p>Anticancer agent 46, potent and selective, induces apoptosis, is cytotoxic to cancer cells, with low toxicity to human lymphocytes.</p>Formula:C22H14ClN3O6S2Color and Shape:SolidMolecular weight:515.95Leukotriene B4 dimethyl amide
CAS:<p>LTB4 dimethyl amide: inhibits human neutrophil degranulation and rat lysozyme release; antagonizes LTB4 receptor on guinea pig lung membranes (Ki = 130 nM).</p>Formula:C22H37NO3Color and Shape:SolidMolecular weight:363.53PptT-IN-3
<p>PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.</p>Formula:C16H27N5O3SColor and Shape:SolidMolecular weight:369.48Antitumor agent-48
<p>Antitumor agent-48, a 2,3-dehydrosilybin derivative, exhibits cytotoxicity on MCF-7, NCI-H1299, HepG2, HT29 cells; IC50 ranging 8.06-16.51 µM.</p>Formula:C35H34N2O14Color and Shape:SolidMolecular weight:706.65Omesdafexor
CAS:<p>Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.</p>Formula:C34H43N3O3Color and Shape:SolidMolecular weight:541.72ADH-6
CAS:<p>ADH-6, a tripyridylamide, disrupts mutant p53 aggregates in cancer cells, reviving its function and inducing apoptosis.</p>Formula:C29H36N8O9Color and Shape:SolidMolecular weight:640.64Lasonolide A
CAS:<p>Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.</p>Formula:C41H60O9Color and Shape:SolidMolecular weight:696.91PSMA-1007
CAS:<p>PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor.</p>Formula:C49H55FN8O16Color and Shape:SolidMolecular weight:1030.01ML-SI1
CAS:<p>ML-SI1, a racemic mixture of diastereoisomers, is a TRPML inhibitor and acts on TRPML1 (IC50: 15 μM).</p>Formula:C23H26Cl2N2O3Color and Shape:SolidMolecular weight:449.37MtTMPK-IN-9
<p>MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.</p>Formula:C25H26N6O7Color and Shape:SolidMolecular weight:522.51Human carbonic anhydrase II-IN-2
<p>Compound R-13, a potent inhibitor of hCA I/II/IV/IX with K i s of 60.7, 320.7, 2298, and 35.2 nM.</p>Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5Bcl-2-IN-7
<p>Bcl-2-IN-7 inhibits Bcl-2, encourages apoptosis in cancer cells, and has anti-tumor activity with various IC50 values.</p>Formula:C24H22N4O5S2Color and Shape:SolidMolecular weight:510.59GPBAR1-IN-3
CAS:<p>GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].</p>Formula:C21H23NO2Color and Shape:SolidMolecular weight:321.41SHR2415
<p>SHR2415: Potent, selective ERK1/2 inhibitor, oral; ERK1 IC50: 2.8 nM, ERK2 IC50: 5.9 nM; effective in Colo205 (IC50: 44.6 nM), for cancer research.</p>Formula:C23H22ClN7O2Color and Shape:SolidMolecular weight:463.92TS010
<p>TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 μM. It holds significant promise for advancements in cancer research [1].</p>Formula:C16H12N4O4SColor and Shape:SolidMolecular weight:356.36Belatacept
CAS:<p>Belatacept (BMS 224818), a T-cell costimulation inhibitor, targets CD80/86 for transplant immunosuppression.</p>Color and Shape:LiquidAntitubercular agent-29
<p>Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.</p>Formula:C20H12ClN3O5Color and Shape:SolidMolecular weight:409.78VEGFR-2-IN-13
<p>VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor (IC50: 3.4 nM). vEGFR-2-IN-13 arrests the HepG2 cell cycle in G2/M phase and induces apoptosis.</p>Formula:C24H18N6O2SColor and Shape:SolidMolecular weight:454.5Anti-inflammatory agent 10
<p>Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.</p>Formula:C17H13BrN4O3S2Color and Shape:SolidMolecular weight:465.345-HT6/5-HT2AR antagonist-1
<p>Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.</p>Formula:C21H26N6SColor and Shape:SolidMolecular weight:394.54SCP1-IN-2
<p>SCP1-IN-2: potent, selective SCP1 inhibitor; induces REST degradation, hinders its activity, may study REST-driven glioblastoma growth.</p>Formula:C19H17F3N2O6S2Color and Shape:SolidMolecular weight:490.4717β-HSD1-IN-1
<p>17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research.</p>Formula:C21H21NO3Color and Shape:SolidMolecular weight:335.4TPI-287
CAS:<p>TPI 287: synthetic taxane; may halt cancer by stabilizing microtubules, blocking cell division, inducing apoptosis.</p>Formula:C46H63NO15Color and Shape:SolidMolecular weight:869.994-Bromo A23187
CAS:<p>4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.</p>Formula:C29H36BrN3O6Purity:98%Color and Shape:SolidMolecular weight:602.52AChE-IN-5
<p>AChE-IN-5: oral, crosses blood-brain barrier, targets AChE/5-HT1A/SERT, potent with 2.29 nM IC50.</p>Formula:C38H45N5OColor and Shape:SolidMolecular weight:587.8VEGFR-2-IN-26
CAS:<p>VEGFR-2-IN-26 inhibits VEGFR-2 (IC50: 15.5 nM), combating various cancers' cell growth.</p>Formula:C24H19F3N6O2Color and Shape:SolidMolecular weight:480.44CHK1-IN-2
CAS:<p>CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).</p>Formula:C20H22N4OSPurity:98%Color and Shape:SolidMolecular weight:366.48Antibacterial agent 77
<p>Antibacterial agent 77 (compound 12) is an antibacterial agent [1].</p>Formula:C22H27N3OSColor and Shape:SolidMolecular weight:381.53CDK8-IN-9
<p>CDK8-IN-9, potent CDK8 inhibitor (IC50: 48.6 nM), curbs tumor growth, useful for colorectal cancer research.</p>Color and Shape:SolidClavicoronic acid
CAS:<p>Clavicoronic acid, a β-lactamase inhibitor, boosts penicillin antibiotics against resistant bacteria.</p>Formula:C15H18O4Color and Shape:SolidMolecular weight:262.3CaMKIIα-IN-1
<p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>Formula:C14H11ClO4Color and Shape:SolidMolecular weight:278.69COX-2/PI3K-IN-2
<p>COX-2/PI3K-IN-2 (5f): anti-inflammatory & anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).</p>Formula:C16H17N5O2Color and Shape:SolidMolecular weight:311.34AChE-IN-24
<p>AChE-IN-24: Strong AChE blocker, crosses blood-brain barrier, IC50=0.053 μM, useful for AD research.</p>Formula:C22H30N2O4S2Color and Shape:SolidMolecular weight:450.61Anticancer agent 79
<p>Anticancer agent 79 (3d) has potent activity against breast cancer, with cytotoxic effects on T47-D, IC50=13.64±0.26μM.</p>Formula:C20H12F3NO5Color and Shape:SolidMolecular weight:403.31Albicidin
CAS:<p>Albicidin is a DNA gyrase inhibitor produced by Xanthomonas albilineans.</p>Formula:C44H38N6O12Color and Shape:SolidMolecular weight:842.818L-Afegostat
CAS:<p>L-Afegostat (5-epi-Isofagomine), an iminosugar, inhibits glycosidase and β-Glucosidase (K i 30 μM), aids in carbohydrate synthesis.</p>Formula:C6H13NO3Color and Shape:SolidMolecular weight:147.17HDAC-IN-47
<p>HDAC-IN-47: Oral HDAC inhibitor (IC50: 19.75-302.73 nM for HDAC1-8), blocks G2/M, inhibits autophagy, triggers apoptosis, anti-cancer in vivo.</p>Formula:C17H20BrN3O4Color and Shape:SolidMolecular weight:410.26LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Formula:C21H11D7F3N5O3Color and Shape:SolidMolecular weight:452.4418-Deoxyherboxidiene
CAS:<p>18-Deoxyherboxidiene (RQN-18690A) inhibits angiogenesis, targeting SF3b in U2 snRNP spliceosome, affects HUVEC, useful for cancer research.</p>Formula:C25H42O5Color and Shape:SolidMolecular weight:422.6DN-F01
<p>DN-F01 exhibits a potent calcium-dependent inhibitory effect on cardiac myofibrillar ATPase activity, with an IC50 of 11 ± 4 nmol/L.</p>Formula:C22H16N2O2Color and Shape:SolidMolecular weight:340.37NUCC-555
CAS:<p>NUCC-555 is a first-in-class antagonist of activin. It opens a completely new approach to inhibiting the activity of TGF-beta receptor superfamily members.</p>Formula:C25H25N5O3Purity:98%Color and Shape:SolidMolecular weight:443.5PCSK9-IN-17
CAS:<p>PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.</p>Formula:C16H19N5OSColor and Shape:SolidMolecular weight:329.42BAY-693
CAS:<p>BAY-693 is a ERK5 negative control agent with IC50 (ERK5) = 6400 nM. Its analog, BAY-885, is a potent and selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM</p>Formula:C26H30F3N7O2Color and Shape:SolidMolecular weight:529.56
