Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,715 products)
- Apoptosis(6,164 products)
- Cell Cycle/Checkpoint(4,727 products)
- Chromatin/Epigenetics(2,400 products)
- Cytoskeletal Signaling(1,492 products)
- DNA Damage/DNA Repair(2,928 products)
- Endocrinology/Hormones(3,653 products)
- Enzyme(3,661 products)
- GPCR/G-Protein(8,861 products)
- Immunology and Inflammation(3,801 products)
- Influenza Virus(299 products)
- JAK/STAT signaling(412 products)
- MAPK Signaling(1,239 products)
- Membrane Transporter/Ion Channel(2,979 products)
- Metabolism(10,029 products)
- Microbiology/Virology(7,445 products)
- Neuroscience(10,281 products)
- Other Inhibitors(36,478 products)
- Oxidation-Reduction(44 products)
- PI3K/Akt/mTOR Signaling(1,443 products)
- Proteases/Proteasome(1,695 products)
- Stem Cell and Derivatives(829 products)
- Tyrosine Kinase/Adaptors(2,035 products)
- Ubiquitination(1,693 products)
Show 16 more subcategories
Found 66676 products of "Inhibitors"
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LT-540-717
CAS:<p>LT-540-717 (compound 32), a potent FLT3 inhibitor (IC50=0.62 nM), exhibits antiproliferative activity and effectively inhibits various acquired FLT3 mutations,</p>Formula:C24H24N8O2Color and Shape:SolidMolecular weight:456.5diMal-O-CH2COOH
CAS:<p>DiMal-O-CH2COOH is a cleavable linker utilized in antibody-drug conjugates (ADCs).</p>Formula:C13H12N2O7Color and Shape:SolidMolecular weight:308.24Igermetostat
CAS:<p>Igermetostat, an EZH2 inhibitor, is utilized both in vivo and in vitro for cancer research [1].</p>Formula:C32H46N4O4Purity:98%Color and Shape:SolidMolecular weight:550.73SARS-CoV-2-IN-68
CAS:<p>SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger</p>Formula:C14H12N2OSePurity:98%Color and Shape:SolidMolecular weight:303.22BET-IN-14
CAS:<p>BET-IN-14 is a pan BET inhibitor with an IC50 of 5.35 nM, demonstrating oral activity and anticancer properties [1].</p>Formula:C30H37N7O2Purity:98%Color and Shape:SolidMolecular weight:527.66JAK-IN-34
CAS:<p>JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3,</p>Formula:C27H26N6OPurity:98%Color and Shape:SolidMolecular weight:450.53Yhhu6669
CAS:<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Formula:C29H28ClFN6O3Purity:98%Color and Shape:SolidMolecular weight:563.02Belfosdil
CAS:Belfosdil is a blocker of antihypertensive calcium channel.Formula:C27H50O7P2Purity:98%Color and Shape:SolidMolecular weight:548.63Bumetanide sodium
CAS:Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).Formula:C17H19N2NaO5SColor and Shape:SolidMolecular weight:386.4EST73502
CAS:<p>EST73502 is a compound that functions as a dual agonist for the μ-opioid receptor (MOR) and an antagonist for the σ1 receptor (σ1R). It is selective, orally active, and possesses the ability to penetrate the blood-brain barrier (BBB). The compound exhibits a Ki value of 64 nM for the MOR and 118 nM for the σ1R. Additionally, EST73502 demonstrates antinociceptive activity [1].</p>Formula:C19H26F2N2O2Purity:98%Color and Shape:SolidMolecular weight:352.426MDL-811
CAS:<p>MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine residues 9, 18, and 56 (H3K9Ac, H3K18Ac, and H3K56Ac),</p>Formula:C25H25BrCl2FN3O5S2Purity:98%Color and Shape:SolidMolecular weight:681.42LFS-1107
CAS:<p>LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].</p>Formula:C12H11N5OS2Purity:98%Color and Shape:SolidMolecular weight:305.38Canlitinib
CAS:<p>Canlitinib, a tyrosine kinase inhibitor, holds potential for cancer research.</p>Formula:C33H31F2N3O7Purity:98%Color and Shape:SolidMolecular weight:619.61YK-029A
CAS:<p>YK-029A, an orally active EGFR mutant inhibitor, targets both EGFR T790M and EGFRex20ins mutations.</p>Formula:C27H32N8O2Purity:98%Color and Shape:SolidMolecular weight:500.6VMAT2-IN-2 tosylate
CAS:<p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>Formula:C27H36F3NO6SPurity:98%Color and Shape:SolidMolecular weight:559.64MDVN1003
CAS:MDVN1003 inhibits BTK & PI3Kδ in B cells, blocking NHL growth; it kills lymphoma cells, not erythroblasts.Formula:C22H20FN7OPurity:98%Color and Shape:SolidMolecular weight:417.44CGP 56999A
CAS:CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.Formula:C19H30NO5PPurity:98%Color and Shape:SolidMolecular weight:383.42JAK1-IN-11
CAS:<p>JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations with IC50 values of 0.02 nM (JAK1) and 0.</p>Formula:C26H36N6O4SPurity:98%Color and Shape:SolidMolecular weight:528.67Tauro-Obeticholic Acid sodium
CAS:<p>Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid.</p>Formula:C28H48NO6S·NaColor and Shape:SolidMolecular weight:549.74Estrogen receptor modulator 8
CAS:<p>Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells</p>Formula:C25H24F4N2O2Purity:98%Color and Shape:SolidMolecular weight:460.46APG-2449
CAS:<p>APG-2449 is an orally active inhibitor targeting ALK, ROS1, and FAK, demonstrating antitumor efficacy in mouse models of non-small cell lung cancer (NSCLC) [1].</p>Formula:C33H42ClN5O4SPurity:98%Color and Shape:SolidMolecular weight:640.24FAP-IN-2
CAS:<p>FAP-IN-2 is a 99mTc-labeled, isonitrile-containing derivative of a fibroblast activation protein (FAPI) inhibitor suitable for tumor imaging [1].</p>Formula:C24H28F2N6O3Color and Shape:SolidMolecular weight:486.51Immune cell migration-IN-1
CAS:<p>Immune cell migration-IN-1 (compound 2) serves as a potent inhibitor of immune cell migration, with potential research applications for mitigating conditions</p>Formula:C30H25ClN4O6SColor and Shape:SolidMolecular weight:605.06DPP
CAS:<p>DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating</p>Formula:C36H40Cl2N2O10PtPurity:98%Color and Shape:SolidMolecular weight:926.7IDO/Tubulin-IN-2
CAS:<p>IDO/Tubulin-IN-2 inhibits TDO/tubulin, effective on U87, HepG2, A549, HCT-116, LO2 cancer cells; IC50 values 0.036-1.04 μM, boosts antitumor action.</p>Formula:C48H40N6O10Color and Shape:SolidMolecular weight:860.87(αR)-Cyclopropaneacetamide-Exatecan
CAS:<p>(αR)-Cyclopropaneacetamide-Exatecan (compound 2-A), an Exenotecan derivative, serves as a cytotoxic agent that effectively inhibits the proliferation of U87MG</p>Formula:C29H28FN3O6Color and Shape:SolidMolecular weight:533.55Lerzeparib
CAS:<p>Lerzeparib is a PARP (ADP-ribose polymerase) inhibitor that exhibits antineoplastic activity [1].</p>Formula:C21H20FN3O2Purity:98%Color and Shape:SolidMolecular weight:365.4FLT3-IN-19
CAS:<p>FLT3-IN-19 (Comp 50) is a potent, selective inhibitor of FLT3, demonstrating an IC50 value of 0.213 nM, and is applicable in research pertaining to acute</p>Formula:C22H26N8OColor and Shape:SolidMolecular weight:418.49JDB175
CAS:<p>JDB175, a selective BTK inhibitor with oral bioavailability, demonstrates excellent penetration through the blood-brain barrier.</p>Formula:C26H21F3N4O2Purity:98%Color and Shape:SolidMolecular weight:478.47Mal-VC-PAB-PNP-CDN-A
CAS:<p>Mal-VC-PAB-PNP-CDN-A is a conjugate comprised of an agent and a linker, utilized in antibody-drug conjugates (ADC) [1] [2].</p>Formula:C51H67N17O20P2Color and Shape:SolidMolecular weight:1300.13Cap-dependent endonuclease-IN-9
CAS:<p>Cap-dependent endonuclease-IN-9, a strong influenza inhibitor, shows low toxicity, good pharmacokinetics, and dynamic action.</p>Formula:C29H22F2N4O7SPurity:98%Color and Shape:SolidMolecular weight:608.57HPK1-IN-38
CAS:<p>HPK1-IN-38 (compound 15) is an inhibitor of MAP4K1/HPK1, suitable for research into disorders related to HPK1 [1].</p>Formula:C29H29N5O3Color and Shape:SolidMolecular weight:495.57Antibacterial agent 160
CAS:<p>Antibacterial Agent 160 is a potent antibacterial agent that rapidly eradicates bacteria and inhibits the formation of bacterial biofilms.</p>Formula:C29H27ClFN3O6Color and Shape:SolidMolecular weight:567.99Antitumor photosensitizer-2
CAS:<p>Compound 11, also known as Antitumor Photosensitizer-2, is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-</p>Formula:C40H47N5O7Color and Shape:SolidMolecular weight:709.83Antibacterial agent 157
CAS:<p>Compound B12 (Antibacterial agent 157) is a fungicidal agent that can impact protein synthesis in Botrytis cinerea.</p>Formula:C26H23BrF4N2O3Color and Shape:SolidMolecular weight:567.37PI3Kδ-IN-13
CAS:<p>PI3Kδ-IN-13 (compound 89), with an IC50 value of 2.6 nM, is an inhibitor of PI3Kδ, applicable for researching diseases involving cell proliferation, including</p>Formula:C27H39N7O4S2Color and Shape:SolidMolecular weight:589.77DiaFluo
CAS:<p>DiaFluo is a probe for protein S-sulfinylation from cells.</p>Formula:C32H32N4O9SColor and Shape:SolidMolecular weight:648.69Ref: TM-T31416
Discontinued productI-BET282
CAS:<p>BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1 (example 2, plC50: 6.0 - 7.0).</p>Formula:C25H30N4O4Purity:98%Color and Shape:SolidMolecular weight:450.53FOXM1-IN-2
CAS:<p>FOXM1-IN-2, a FOXM1 inhibitor, exhibits antineoplastic activity [1].</p>Formula:C48H47F4N7O12SColor and Shape:SolidMolecular weight:1021.99Omeprazole acid
CAS:Omeprazole treats GERD, ulcers, Zollinger-Ellison syndrome, prevents GI bleeding; it's a proton pump inhibitor.Formula:C34H32N6Na2O10S2Color and Shape:SolidMolecular weight:794.76BCR-ABL-IN-8
CAS:<p>BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].</p>Formula:C30H33N7O5Purity:98%Color and Shape:SolidMolecular weight:571.63AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Formula:C29H40O3Purity:99.58%Color and Shape:SolidMolecular weight:436.63Anti-MI/R injury agent 1
CAS:<p>Anti-MI/R injury agent 1 (compound 18), derived from Panaxatriol, represents an orally administered, potent agent against myocardial ischemia/reperfusion (MI/R</p>Formula:C32H49NO6Color and Shape:SolidMolecular weight:543.73Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE
CAS:<p>Compound S6, Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE, is a potent anticancer agent specifically activated by the tumor microenvironment; it demonstrates efficacy</p>Formula:C67H101N11O16Purity:98%Color and Shape:SolidMolecular weight:1316.58BTK-IN-25
CAS:<p>BTK-IN-25 (compound 71) is a potent BTK inhibitor, demonstrating an IC50 of 0.77 nM against BTK(C481S) and achieving an IC50 of 1 nM in DOHH2 cells [1].</p>Formula:C28H27F2N3O5Purity:98%Color and Shape:SolidMolecular weight:523.53ALPK1-IN-3
CAS:<p>ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced</p>Formula:C20H16F2N4OSPurity:98%Color and Shape:SolidMolecular weight:398.43BBDDL2059
CAS:<p>BBDDL2059 is a selective covalent inhibitor targeting EZH2, exhibiting an IC50 of 1.5 nM against the EZH2-Y641F mutant.</p>Formula:C27H36N4O4SPurity:98%Color and Shape:SolidMolecular weight:512.66CYY292
CAS:<p>CYY292 is a chemical compound acting as an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3, with respective IC50 values of 5.35, 4.6, 28, 28, and 78 nM.</p>Formula:C24H28N8OColor and Shape:SolidMolecular weight:444.53Xilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Formula:C26H37N3O2Purity:98%Color and Shape:SolidMolecular weight:423.59STAT3-IN-18
CAS:<p>STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and</p>Formula:C18H24Cl2N2O6PtPurity:98%Color and Shape:SolidMolecular weight:630.38Insecticidal agent 6
CAS:<p>Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.</p>Formula:C19H14BrCl2N5O4Purity:98%Color and Shape:SolidMolecular weight:527.16L 689037
CAS:L 689037 is an inhibitor of leukotriene biosynthesis.Formula:C36H37ClN2O4Purity:98%Color and Shape:SolidMolecular weight:597.14HBV-IN-38
CAS:<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Formula:C18H16F3N5O4S2Purity:98%Color and Shape:SolidMolecular weight:487.48Syk-IN-8
CAS:<p>Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.</p>Formula:C23H26N10Purity:98%Color and Shape:SolidMolecular weight:442.52S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Formula:C25H26F3NO3Purity:98%Color and Shape:SolidMolecular weight:445.47CIAC001
CAS:<p>CIAC001, a pyruvate kinase PKM2 inhibitor, exhibits anti-neuroinflammatory properties.</p>Formula:C20H25N3O2Color and Shape:SolidMolecular weight:339.43URAT1 inhibitor 5
CAS:<p>URAT1 Inhibitor 5 (compound 16) serves as a powerful inhibitor of URAT1 and is utilized in hyperuricemia research [1].</p>Formula:C18H14BrN3O2SColor and Shape:SolidMolecular weight:416.29ATR-IN-24
CAS:<p>ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].</p>Formula:C23H26N6O2Purity:98%Color and Shape:SolidMolecular weight:418.49BTK-IN-27
CAS:<p>BTK-IN-27 (example 8), a potent BTK inhibitor with an IC50 of 0.2 nM, demonstrates anti-proliferative effects in TMD8 cells with an IC50 of less than 5 nM.</p>Formula:C31H35N7O2Purity:98%Color and Shape:SolidMolecular weight:537.66ROCK2-IN-6
CAS:<p>ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].</p>Formula:C26H21F2N7OPurity:98%Color and Shape:SolidMolecular weight:485.49URAT1&XO inhibitor 1
CAS:<p>URAT1&XO Inhibitor 1 (compound 29) serves as a dual inhibitor with IC50 values of approximately 10 μM for URAT1 and 1.01 μM for Xanthine Oxidase.</p>Formula:C20H13N5O3SPurity:98%Color and Shape:SolidMolecular weight:403.41SHP2-IN-14
CAS:<p>SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM.</p>Formula:C22H20Cl2N8OColor and Shape:SolidMolecular weight:483.35Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan
CAS:<p>Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan is a linker molecule employed in the synthesis of antibody-drug conjugates (ADCs), demonstrating potent antitumor</p>Formula:C55H60FN9O13Color and Shape:SolidMolecular weight:1074.12Davelizomib
CAS:<p>Davelizomib is a proteasome inhibitor that exhibits antineoplastic activity [1].</p>Formula:C21H26BF2N3O7Purity:98%Color and Shape:SolidMolecular weight:481.25LM2I
CAS:<p>LM2I, a derivative of Spinosyn A (SPA), serves both as an argininosuccinate synthase (ASS1) enzyme activator and a tumor inhibitor through direct interaction</p>Formula:C47H77N3O11Color and Shape:SolidMolecular weight:860.13JAK1-IN-10
CAS:<p>JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor of JAK1 [1].</p>Formula:C15H17N7Purity:98%Color and Shape:SolidMolecular weight:295.34PHI-101
CAS:<p>PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.</p>Formula:C19H19FN4O2SPurity:99.4%Color and Shape:SolidMolecular weight:386.44Dimethandrolone Undecanoate
CAS:Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.Formula:C31H50O3Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:470.73Ref: TM-T27176
Discontinued productROCK-IN-6
CAS:<p>ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1</p>Formula:C19H19N5O8SPurity:98%Color and Shape:SolidMolecular weight:477.45Ifetroban sodium
CAS:<p>Ifetroban sodium (BMS-180291), oral TXA2/PGH2 antagonist for researching heart, stroke, BP, thrombosis.</p>Formula:C25H31N2NaO5Color and Shape:SolidMolecular weight:462.522DG026
CAS:DG026 selectively inhibits IRAP, reducing its cross-presentation in dendritic cells without affecting ERAP1.Formula:C35H40N3O4PPurity:98%Color and Shape:SolidMolecular weight:597.68BPH-628
CAS:<p>BPH-628 is a bioactive chemical.</p>Formula:C20H20O7P2Color and Shape:SolidMolecular weight:434.32Cortivazol
CAS:Cortivazol is an Anti-Inflammatory Drug.Formula:C32H38N2O5Purity:98%Color and Shape:SolidMolecular weight:530.65Ifetroban
CAS:<p>Ifetroban is a potent and selective TxA2/PGH2 receptor antagonist.</p>Formula:C25H32N2O5Color and Shape:SolidMolecular weight:440.53ALS-I-41
CAS:ALS-I-41 is a novel, potent and selective antagonist of oxytocin receptor.Formula:C30H38FN3O6SPurity:98%Color and Shape:SolidMolecular weight:587.7hDHODH-IN-8
<p>hDHODH-IN-8 is a potent human dihydroorotic dehydrogenase (hDHODH) inhibitor (IC50: 16 nM) that exhibits potent antiproliferative effects and has good water solubility, with potential for oncology studies, especially in lymphoma.</p>Formula:C21H15F6N3O4Purity:98%Molecular weight:487.35
