Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,838 products)
- Apoptosis(6,316 products)
- Cell Cycle/Checkpoint(4,881 products)
- Chromatin/Epigenetics(2,615 products)
- Cytoskeletal Signaling(1,570 products)
- DNA Damage/DNA Repair(2,868 products)
- Endocrinology/Hormones(3,753 products)
- Enzyme(3,673 products)
- GPCR/G-Protein(9,023 products)
- Immunology and Inflammation(3,903 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,258 products)
- Membrane Transporter/Ion Channel(3,159 products)
- Metabolism(10,130 products)
- Microbiology/Virology(7,618 products)
- Neuroscience(10,516 products)
- Other Inhibitors(35,844 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,431 products)
- Proteases/Proteasome(1,688 products)
- Stem Cell and Derivatives(729 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,727 products)
Show 16 more subcategories
Found 66513 products of "Inhibitors"
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Apratastat
CAS:Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)Formula:C17H22N2O6S2Purity:98%Color and Shape:SolidMolecular weight:414.5S 16020-2
CAS:S 16020-2 is an olivacine derivative, and DNA topoisomerase II inhibitor endowed with a remarkable antitumor activity against various experimental tumors.Formula:C22H26Cl2N4O2Color and Shape:SolidMolecular weight:449.376Cyclic HPMPC
CAS:Cyclic HPMPC: Potent antiviral, raises O2 in mice with lethal vaccinia, lowers guinea pig CMV replication.Formula:C8H12N3O5PColor and Shape:SolidMolecular weight:261.17LXR agonist 1
CAS:Potent LXR agonist; AC50: 1.5 nM (LXR-α), 12 nM (LXR-β); potential in atherosclerosis research.Formula:C27H26F3N3O3SColor and Shape:SolidMolecular weight:529.57NMS-P953
CAS:NMS-P953: JAK2 inhibitor, reduces tumor growth in SET-2 model, confirmed in vivo action, good pharmacokinetics and safety.Formula:C16H11ClF3N5OColor and Shape:SolidMolecular weight:381.74KRAS G12C mutant protein inhibitor A-1
CAS:KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras.Formula:C31H26ClF4N7O2Color and Shape:SolidMolecular weight:640.03GT-2394
CAS:GT-2394 is a histamine H3 receptor agonist.Formula:C14H21N3O2Color and Shape:SolidMolecular weight:263.34Antituberculosis agent-8
CAS:Antituberculosis agent-8: MIC 3.53 μM vs M. tuberculosis, antifungal MIC 62.50 μM vs A. niger.Formula:C25H19F3N2O3Color and Shape:SolidMolecular weight:452.43(R)-3,4-DCPG
CAS:AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptorsFormula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18ARN-21934
CAS:ARN-21934 inhibits human topoisomerase II α/β; IC50=2μM; stronger than Etoposide (IC50=120μM) in DNA relaxation.Formula:C21H24N6Purity:99.8%Color and Shape:SolidMolecular weight:360.46Ref: TM-T36968
1mg62.00€2mg89.00€5mg135.00€1mL*10mM (DMSO)149.00€10mg212.00€25mg373.00€50mg509.00€100mg702.00€200mg944.00€Benzyl alcohol, α-(4-(4-amino-2-methoxyphenoxy)butyl)-, acetate (ester)
CAS:Benzyl alcohol, alpha-(4-(4-amino-2-methoxyphenoxy)butyl)-, acetate (ester) is a bioactive chemical.Formula:C20H25NO4Color and Shape:SolidMolecular weight:343.42JNJ-28583867
CAS:JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.Formula:C24H32N2O2SColor and Shape:SolidMolecular weight:412.59GABAA receptor agent 2 TFA
CAS:Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.Formula:C22H22F3N3O3Color and Shape:SolidMolecular weight:433.42NCQ-469
CAS:NCQ-469 is a metabolite of remoxipride and a dopamine D2 receptor antagonist.Formula:C16H23BrN2O4Color and Shape:SolidMolecular weight:387.27FGFR-IN-2
CAS:FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).Formula:C25H30N6O2Color and Shape:SolidMolecular weight:446.54SRX 251
CAS:SRX 251, a vasopressin V1a receptor antagonist, is used potentially for the treatment of primary dysmenorrhea.Formula:C43H48F3N5O5Color and Shape:SolidMolecular weight:771.87CE-178,253
CAS:CE-178,253 is a selective centrally-acting CB1 receptor antagonist.Formula:C24H23Cl2N7OColor and Shape:SolidMolecular weight:496.39DC 432
CAS:DC 432, a potent peptidomimetic inhibitor of N-terminal methyltransferase 1/2 (NTMT1/2) with an IC50 value of 54 nM, incorporates a BM30 peptide enhanced byFormula:C55H100N28O10Color and Shape:SolidMolecular weight:1313.59LY108742
CAS:LY108742 is an antagonist of 5-HT2.Formula:C21H28N2O3Purity:98%Color and Shape:SolidMolecular weight:356.46Efipladib
CAS:Efipladib is a phospholipase inhibitor. Efipladib decreases nociceptive responses without affecting PGE2 levels in the cerebral spinal fluid.Formula:C40H35Cl3N2O4SColor and Shape:SolidMolecular weight:746.14PF-04957325
CAS:PF-04957325 is an inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A.PF-04957325 can be used for the study of autoimmune encephalomyelitis.Formula:C14H15F3N8OSPurity:99.02%Color and Shape:SolidMolecular weight:400.38Ref: TM-T12422
1mg130.00€1mL*10mM (DMSO)195.00€5mg222.00€10mg334.00€25mg578.00€50mg838.00€100mg1,251.00€ROCK-IN-7
CAS:ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].Formula:C17H17N3O2SPurity:98%Color and Shape:SolidMolecular weight:327.4YAP-TEAD-IN-2
CAS:YAP-TEAD-IN-2 (compound 6) serves as a potent inhibitor of the YAP-TEAD protein-protein interaction (PPI), demonstrating an inhibitory concentration 50 (IC50)Formula:C25H24ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:470.92BT-GSI
BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.Formula:C26H46BrN5O10P2Color and Shape:SolidMolecular weight:730.52GSK3491943
CAS:GSK3491943 is a potent TRPV4 inhibitor with IC50 = 3.2 nM. GSK3491943 is a potential agent for the treatment of heart failure and respiratory diseases.Formula:C18H16Cl2N2O5SColor and Shape:SolidMolecular weight:443.3N-Benzylnaltrindole hydrochloride
CAS:δ2 opioid receptor antagonistFormula:C33H33ClN2O3Purity:98%Color and Shape:SolidMolecular weight:541.08T-00127_HEV1
CAS:T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta(PI4KIIIβ, IC50 = 60 nM).Formula:C22H29N5O3Purity:99.89%Color and Shape:SolidMolecular weight:411.5Ref: TM-T16967
1mg52.00€5mg113.00€10mg177.00€1mL*10mM (DMSO)234.00€25mg355.00€50mg530.00€100mg758.00€500mg1,558.00€BPIQ-I
CAS:BPIQ-I (PD 159121), an ATP-competitive EGFR tyrosine kinase inhibitor, exhibits potent anti-proliferative activity.Formula:C16H12BrN5Color and Shape:SolidMolecular weight:354.2BY27
CAS:BY27 is a BET BD2 inhibitor with anticancer activity that inhibits BRD2, BRD3 and BRD4 and suppresses tumor growth.Formula:C22H21ClN6Purity:99.4% - 99.68%Color and Shape:SolidMolecular weight:404.89Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Formula:C22H25Cl2N3O3Purity:99.36%Color and Shape:SolidMolecular weight:450.36Ref: TM-T14782
1mg100.00€5mg236.00€1mL*10mM (DMSO)268.00€10mg385.00€25mg663.00€50mg954.00€100mg1,305.00€200mg1,738.00€A 69992
CAS:A 69992 is an HIV anti-infective nucleoside.Formula:C11H14N5O3TPurity:98%Color and Shape:SolidMolecular weight:267.28CCPG
CAS:CCPG is an agonist of excitatory Amino Acid.Formula:C6H9NO4Purity:98%Color and Shape:SolidMolecular weight:159.14WRN inhibitor 3
CAS:WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).Formula:C20H20N2O5SColor and Shape:SolidMolecular weight:400.45ZK824190
CAS:ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.Formula:C22H20F2N2O4Purity:98.84%Color and Shape:SolidMolecular weight:414.4Ref: TM-T13408
1mg152.00€5mg306.00€1mL*10mM (DMSO)318.00€10mg442.00€25mg675.00€50mg900.00€100mg1,224.00€GNE 220
CAS:GNE-220 is a potent and selective inhibitor of MAP4K4 (IC50: 7 nM).Formula:C25H26N8Purity:98%Color and Shape:SolidMolecular weight:438.53Adipiplon
CAS:Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Formula:C18H18FN7Color and Shape:SolidMolecular weight:351.38Ritodrine
CAS:Ritodrine (DU21220) is a β-adrenergic agonist as well as an effective uterine relaxant that can be used in arrest premature labor research[1] [2].Formula:C17H21NO3Color and Shape:SolidMolecular weight:287.35PCSK9-IN-15
CAS:PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, K D <200 nM) that plays a crucial role in cholesterolFormula:C22H28N6O2S2Color and Shape:SolidMolecular weight:472.63rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Formula:C18H21FN4O2Purity:99.44%Color and Shape:SolidMolecular weight:344.38L-749329
CAS:L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.Formula:C28H29NO8SPurity:98%Color and Shape:SolidMolecular weight:539.6KB-R7785
CAS:KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.Formula:C18H27N3O4Color and Shape:SolidMolecular weight:349.42CCG-203586
CAS:CCG-203586 is a novel potent glucosylceramide synthase (GCS) inhibitor.Formula:C26H32N2O4Color and Shape:SolidMolecular weight:436.541-Methoxyphaseollidin
CAS:1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.Formula:C21H22O5Purity:98%Color and Shape:SolidMolecular weight:354.4STAT3-IN-14
CAS:STAT3-IN-14 is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 can directly bind to the hinge region of STAT3 .Formula:C14H10O5Color and Shape:SolidMolecular weight:258.23Indimilast
CAS:Indimilast blocks PDE4, reducing lung inflammation and bronchiectasis, possibly treating COPD.Formula:C37H40FN7O3SColor and Shape:SolidMolecular weight:681.82α,β-Methylene-ATP
CAS:α,β-Methylene ATP，一种ATP的膦酸酯类似物，充当P2X3和P2X7受体的配体。该化合物对P2X1和P2X3表现出高选择性激动剂活性，而在P2X2, 4, 7受体上无活性。Formula:C11H18N5O12P3Color and Shape:SolidMolecular weight:505.21IPG7236
CAS:IPG7236, a selective CCR8 antagonist, demonstrates notable tumor suppression in a mouse xenograft model of human breast cancer and is applicable in cancerFormula:C23H31N3O3SPurity:98%Color and Shape:SolidMolecular weight:429.58PF-06679142
CAS:PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.Formula:C20H17F2NO3Purity:98%Color and Shape:SolidMolecular weight:357.35PARP1-IN-7
CAS:PARP1-IN-7 functions as an anticancer agent by inhibiting poly(ADP-ribose) polymerase-1 (PARP1).Formula:C24H23N5OColor and Shape:SolidMolecular weight:397.47H4R antagonist 2
CAS:H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoidFormula:C13H17N5OPurity:98%Color and Shape:SolidMolecular weight:259.31
