Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,834 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,877 products)
- Chromatin/Epigenetics(2,613 products)
- Cytoskeletal Signaling(1,568 products)
- DNA Damage/DNA Repair(2,871 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,020 products)
- Immunology and Inflammation(3,905 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,257 products)
- Membrane Transporter/Ion Channel(3,155 products)
- Metabolism(10,133 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,473 products)
- Other Inhibitors(35,846 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,689 products)
- Stem Cell and Derivatives(732 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66515 products of "Inhibitors"
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TA-316
CAS:Agent induces megakaryocytes/platelets from stem cells to treat thrombopenia.Formula:C28H25BrN4O5S2Purity:98%Color and Shape:SolidMolecular weight:641.56RSV-IN-5
CAS:RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.Formula:C28H37N7O2Color and Shape:SolidMolecular weight:503.64J-104871
CAS:J-104871 (UNII-6137X5QNJF) is an FTase inhibitor that inhibits tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.Formula:C38H32N2O12Purity:99.03%Color and Shape:SolidMolecular weight:708.67Massarilactone H
CAS:Massarilactone H, a polyketide, is a neuraminidase inhibitor, with an IC 50 of 8.18 µM .Formula:C11H12O5Color and Shape:SolidMolecular weight:224.21PIM-1/HDAC-IN-1
PIM-1/HDAC-IN-1 (4d): inhibits PIM-1 (IC50: 343.87nM), HDAC1 (63.65nM), HDAC6 (62.39nM); induces apoptosis in MCF-7 cells.Formula:C22H19N3O3Color and Shape:SolidMolecular weight:373.4RORγt/DHODH-IN-3
RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 hasFormula:C24H26ClF6N3O3SColor and Shape:SolidMolecular weight:585.99Amicoumacin A
CAS:Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.Formula:C20H29N3O7Purity:98%Color and Shape:SolidMolecular weight:423.46TGR5 Receptor Agonist 3
CAS:TGR5 Receptor Agonist 3 is a GPBAR1 agonist with EC50 of 16.4 nM (hTGR5) & 209 nM (mTGR5), ensures gallbladder safety and reduces filling.Formula:C29H27N3O6Color and Shape:SolidMolecular weight:513.54AVE 0991
CAS:AVE 0991 is a nonpeptide analog of angiotensin-(1-7), a Mas agonist with inhibitory effects on [125I]-Ang-(1-7) and on neuroinflammation in Alzheimer's disease.Formula:C29H32N4O5S2Purity:99.73%Color and Shape:SolidMolecular weight:580.72Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Formula:C21H19F2N7O3S2Color and Shape:SolidMolecular weight:519.55FGFR-IN-6
CAS:FGFR-IN-6 (Compound 5) is an FGFR inhibitor.Formula:C23H22N6O3Color and Shape:SolidMolecular weight:430.46DL-Buthionine-(S,R)-sulfoximine hydrochloride
DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent and specific glutamylcysteine synthetase biosynthesis inhibitorFormula:C8H19ClN2O3SColor and Shape:SolidMolecular weight:258.77P-gp inhibitor 2
CAS:Potent P-gp inhibitor 2 reverses Doxorubicin resistance in colorectal carcinoma cells with IC50 of 0.22 µM.Formula:C29H26N2O6Color and Shape:SolidMolecular weight:498.53MtTMPK-IN-3
CAS:MtTMPK-IN-3 inhibits Mycobacterium tuberculosis kinase with IC50 0.12μM, MIC 12.5μM on Mtb, cytotoxic EC50 12.5μM on MRC-5 cells.Formula:C23H23Cl2N3O3Color and Shape:SolidMolecular weight:460.35GSK-3036656 free base
CAS:GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.Formula:C10H13BClNO4Color and Shape:SolidMolecular weight:257.48Vindeburnol
CAS:Vindeburnol is a cerebral vasodilator vincamine analog that bears neuroprotective properties.Formula:C17H20N2OColor and Shape:SolidMolecular weight:268.35Cap-dependent endonuclease-IN-14
CAS:Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).Formula:C30H23FN2O6SColor and Shape:SolidMolecular weight:558.58BMS-066
CAS:BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.Formula:C19H21N7O2Purity:98%Color and Shape:SolidMolecular weight:379.42RIP1 kinase inhibitor 1
CAS:RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04.Formula:C24H20ClN5O3Purity:98%Color and Shape:SolidMolecular weight:461.9(-)-15-Deoxyspergualin
CAS:(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.Formula:C17H37N7O3Color and Shape:SolidMolecular weight:387.52IAA65
CAS:IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].Formula:C16H13F6NO2Color and Shape:SolidMolecular weight:365.27Aeruginosin 98-B
CAS:Aeruginosin 98-B, a protease inhibitor, effectively inhibits trypsin, plasmin, and thrombin with IC50 values of 0.6, 7.0, and 10.0 μg/mL, respectively.Formula:C29H46N6O9SColor and Shape:SolidMolecular weight:654.78YEATS4 binder-1
YEATS4 binder-1(4e) is an effective and selective compound that targets the KAc recognition site within the YEATS structural domain, exhibiting a bindingFormula:C23H34N4O3Color and Shape:SolidMolecular weight:414.54KRas G12C inhibitor 2
CAS:KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.Formula:C32H37N7O3Purity:98%Color and Shape:SolidMolecular weight:567.68Antibacterial agent 63
CAS:Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to aFormula:C35H43N9O14S2Color and Shape:SolidMolecular weight:877.9GPR81 agonist 2
CAS:GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 µM for hGPR81 and 0.123 µM for hGPR109A, respectively.Formula:C26H27ClN6O5S2Color and Shape:SolidMolecular weight:603.11Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formula:C22H28N6OColor and Shape:SolidMolecular weight:392.5NS2B/NS3-IN-5
Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.Formula:C14H9IN2O3SColor and Shape:SolidMolecular weight:412.2ATR-IN-17
CAS:ATR-IN-17 is a potent inhibitor of ATR kinase with good anti-cancer effects in LoVo cells (IC50: 1 nM).Formula:C22H28N6O2SColor and Shape:SolidMolecular weight:440.56KRAS G12C inhibitor 37
CAS:KRAS G12C inhibitor 37 targets a key signaling protein, showing promise for cancer research involving KRAS G12C.Formula:C35H39F3N8O2Color and Shape:SolidMolecular weight:660.73Mf 268
CAS:Mf 268 is a pseudo-reversible carbamate-type inhibitor which interacts with the catalytic and regulatory anionic site of the enzyme.Formula:C28H46N4O3Color and Shape:SolidMolecular weight:486.69GENZ-882706
CAS:GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.Formula:C26H25N5O3Purity:98%Color and Shape:SolidMolecular weight:455.51Porphobilinogen
CAS:Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.Formula:C10H14N2O4Purity:98%Color and Shape:SolidMolecular weight:226.23Efrapeptin F
CAS:Efrapeptin F, from Tolypocladium fungi, inhibits mitochondrial complex V and targets nutrient-deprived tumor cells.Formula:C82H141N18O16Color and Shape:SolidMolecular weight:1635.11DGY-08-097
CAS:DGY-08-097: potent HCV NS3 degrader, low resistance risk, strong inhibition in cells, DC50 of 50nM at 4h.Formula:C60H76N10O14Color and Shape:SolidMolecular weight:1161.3Rostratin B
CAS:Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.Formula:C18H20N2O6S2Color and Shape:SolidMolecular weight:424.49GSK-2878175
CAS:GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Formula:C27H23BClFN2O6SPurity:98%Color and Shape:SolidMolecular weight:568.81rel-MDM2/4-p53-IN-2
Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.Formula:C25H17Cl3FN3O3Color and Shape:SolidMolecular weight:532.78BMS-986120
CAS:BMS-986120: Oral, reversible PAR4 antagonist. IC50: 9.5 nM (human), 2.1 nM (monkey). Potent, selective antiplatelet.Formula:C23H23N5O5S2Color and Shape:SolidMolecular weight:513.59S100A2-p53-IN-1
CAS:S100A2-p53-IN-1 inhibits S100A2-p53 in pancreatic cancer, stunting MiaPaCa-2 cell growth at 1.2-3.4 μM.Formula:C20H20F6N2O4SColor and Shape:SolidMolecular weight:498.44microRNA-21-IN-1
CAS:microRNA-21-IN-1: microRNA inhibitor, curbs HeLa/HCT-116 growth (IC50: 5.5/2.8 μM), induces HeLa apoptosis, elevates PTEN/EGR1/SLIT2, for cancer research.Formula:C30H37FN6O3Color and Shape:SolidMolecular weight:548.65NLRP3-IN-4
NLRP3-IN-4 is an effective, oral NLRP3 inflammasome inhibitor with potent anti-inflammatory effects on colitis.Formula:C22H22N2O5Color and Shape:SolidMolecular weight:394.42Antimalarial agent 3
Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.Formula:C15H16BrN3O2Color and Shape:SolidMolecular weight:350.21Onfasprodil
CAS:Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)Formula:C20H23FN2O3Color and Shape:SolidMolecular weight:358.41IRL 2500
CAS:IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.Formula:C36H35N3O4Purity:99.36%Color and Shape:White Crystalline SolidMolecular weight:573.68L-739750
CAS:L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.Formula:C23H39N3O6S2Purity:98%Color and Shape:SolidMolecular weight:517.7A 74273
CAS:A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.Formula:C44H74N4O8Purity:98%Color and Shape:SolidMolecular weight:787.08Dual AChE-MAO B-IN-1
Dual AChE-MAO B-IN-1: orally active CNS-permeable, safe, stable neuroprotective agent; AChE IC50=550 nM, MAO-B IC50=8.2 nM.Formula:C23H25F2NO4Color and Shape:SolidMolecular weight:417.45SHP2-IN-9
SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.Formula:C20H20FN3O2SColor and Shape:SolidMolecular weight:385.4620S Proteasome-IN-4
CAS:20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.Formula:C20H18ClF2N3O3Color and Shape:SolidMolecular weight:421.83
