Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,834 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,613 products)
- Cytoskeletal Signaling(1,567 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,015 products)
- Immunology and Inflammation(3,904 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,257 products)
- Membrane Transporter/Ion Channel(3,155 products)
- Metabolism(10,137 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,442 products)
- Other Inhibitors(35,847 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(732 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66515 products of "Inhibitors"
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ERK2 IN-1
CAS:ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.Formula:C36H34FN7O2SPurity:98%Color and Shape:SolidMolecular weight:647.76A25822B
CAS:A25822B is an antifungal agent.Formula:C28H45NOPurity:98%Color and Shape:SolidMolecular weight:411.66Diacylglycerol acyltransferase inhibitor-1
CAS:Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.Formula:C21H23N5O2Purity:98%Color and Shape:SolidMolecular weight:377.44AP5
CAS:AP5: GPR40 agonist, positive allosteric modulator; rat hIP1 EC50: 0.49 nM.Formula:C28H28FNO4Purity:98%Color and Shape:SolidMolecular weight:461.525α-reductase-IN-1
CAS:5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase.Formula:C31H37NO5Purity:98%Color and Shape:SolidMolecular weight:503.63LSD1-IN-22
LSD1-IN-22: potent LSD1 inhibitor, K_i 98 nM, curbs cancer cell growth.Formula:C9H8BrF2NColor and Shape:SolidMolecular weight:248.07Basroparib
CAS:Basroparib is an inhibitor of ribose polymerase (PARP) and has shown antitumour effects.Formula:C18H21F2N7O3Color and Shape:SolidMolecular weight:421.4RDN2150
CAS:RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69Formula:C28H29ClN8O4Color and Shape:SolidMolecular weight:577.03(±)-ANAP hydrochloride
CAS:'(±)-ANAP hydrochloride, an unnatural amino acid analog of prodan, serves as a fluorescent probe with enhanced environmental sensitivity.'Formula:C15H17ClN2O3Color and Shape:SolidMolecular weight:308.76WS-898
WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.Formula:C33H25N7OSColor and Shape:SolidMolecular weight:567.66Elongation factor P-IN-1
EFP-IN-1: potent β-lysine derivative, inhibits EFP, slows E. coli growth.Formula:C14H31N3O2Color and Shape:SolidMolecular weight:273.41XP5
XP5 is an oral HDAC6 inhibitor, potent against cancer cells, including YCC3/7 (IC50=31 nM to 2.31 μM).Formula:C19H25N3O5SColor and Shape:SolidMolecular weight:407.48Integrase-LEDGF/p75 allosteric inhibitor 1
CAS:Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).Formula:C33H41NO6SColor and Shape:SolidMolecular weight:579.75PDE4B-IN-3
PDE4B-IN-3 is a potent inhibitor of PDE4B (IC50: 0.94 μM) and exhibits anti-inflammatory effects.Formula:C30H35N3O4S2Color and Shape:SolidMolecular weight:565.75QCA570
CAS:QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein).Formula:C39H33N7O4SPurity:98%Color and Shape:SolidMolecular weight:695.79S100A2-p53-IN-1
CAS:S100A2-p53-IN-1 inhibits S100A2-p53 in pancreatic cancer, stunting MiaPaCa-2 cell growth at 1.2-3.4 μM.Formula:C20H20F6N2O4SColor and Shape:SolidMolecular weight:498.44EGFR/BRAF-IN-1
EGFR/BRAF-IN-1 inhibits EGFR/BRAF (BRAFV600E IC50: 45 nM, GI50: 35 nM) and has antioxidant properties.Formula:C26H28ClN3O4Color and Shape:SolidMolecular weight:481.97Oberadilol
CAS:Oberadilol is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory actionFormula:C25H30ClN5O3Color and Shape:SolidMolecular weight:483.99Karenitecin
CAS:Karenitecin (Cositecan) is an inhibitor of topoisomerase I. It has potent anti-cancer activity.Formula:C25H28N2O4SiPurity:98%Color and Shape:SolidMolecular weight:448.59Soyacerebroside II
CAS:Soyacerebroside II is a Ca2+ ionophore; both I and II inhibit IL-18 in PBMCs and modulate immune responses.Formula:C40H75NO9Purity:98%Color and Shape:SolidMolecular weight:714.02U75302
CAS:U75302 is an antagonist of thymosin beta-4 (TB4) receptor with a Ki value of 159 nM on guinea pig lung membranes.Formula:C22H35NO3Purity:98%Color and Shape:Light Yellow OilMolecular weight:361.52HP590
CAS:HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.Formula:C29H24F6N4O3Color and Shape:SolidMolecular weight:590.52XY153
XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.Formula:C33H34FN3O4Color and Shape:SolidMolecular weight:555.64CBP/p300-IN-18
CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).Formula:C25H27FN4O3Color and Shape:SolidMolecular weight:450.51PARP-1-IN-1
PARP-1-IN-1: Selective, oral PARP-1 inhibitor with 0.96 nM IC50; well-tolerated and effective in single-dose MDA-MB-436 model.Formula:C23H25FN4OColor and Shape:SolidMolecular weight:392.47BChE-IN-5
BChE-IN-5: potent, selective BChE inhibitor (IC50: 2.8 nM), more effective on hBChE, potential in Alzheimer's research.Formula:C30H42N4OColor and Shape:SolidMolecular weight:474.68PPARγ agonist 2
PPARγ agonist 2 is a highly effective compound that acts as a partial agonist for PPARγ.Formula:C24H20O5Color and Shape:SolidMolecular weight:388.41Exicorilant
CAS:Exicorilant is a selective oral GR antagonist (Ki: 7 nM) that may reduce obesity, glucose intolerance, & dyslipidemia.Formula:C26H23F4N7O3SPurity:98%Color and Shape:SolidMolecular weight:589.56GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Formula:C17H16ClN3O4Purity:98%Color and Shape:SolidMolecular weight:361.78ICA-105665
CAS:ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.Formula:C19H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:355.34GSK945237
CAS:GSK945237 is a type IIA topoisomerase inhibitor, effective on Gram-positive and negative bacteria, with favorable pharmacokinetics and in vivo efficacy.Formula:C24H26FN5O3Color and Shape:SolidMolecular weight:451.49GGTI298
CAS:GGTI298 is a potent GGTase I inhibitor; IC50 3μM for Rap1A, >20μM for Ha-Ras.Formula:C27H33N3O3SPurity:98%Color and Shape:SolidMolecular weight:479.63Atiratecan
CAS:Atiratecan (TP300), a CH0793076-based camptothecin prodrug, combats BCRP+/- tumors; doesn't affect AChE.Formula:C31H34N6O6Purity:98%Color and Shape:SolidMolecular weight:586.64Dyrk1A-IN-1
Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity, aggregation of tau and α-syn oligomers, with an IC50 value of 119 nM for Dyrk1A kinase.Formula:C23H20N4O3SColor and Shape:SolidMolecular weight:432.49DG013A
CAS:DG013A inhibits ERAP1 & ERAP2 (IC50: 33 nM & 11 nM) to research autoimmune diseases & cancer.Formula:C27H37N4O4PColor and Shape:SolidMolecular weight:512.58L-739750
CAS:L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.Formula:C23H39N3O6S2Purity:98%Color and Shape:SolidMolecular weight:517.7Naltalimide
CAS:Naltalimide: µ-opioid receptor partial agonist, improves bladder storage by affecting spinal cord reflex.Formula:C28H28N2O5Purity:98%Color and Shape:SolidMolecular weight:472.53(2S,4S)-Sacubitril
CAS:(2S,4S)-Sacubitril (Sacubitril Impurity C) is a stereoisomer derived from Sacubitril which is a potent NEP inhibitor.Formula:C24H29NO5Purity:98%Color and Shape:SolidMolecular weight:411.49LLS30
CAS:LLS30 inhibits Gal-1, reduces its binding affinity, and may help treat advanced prostate cancer.Formula:C34H33Cl4N5O3Color and Shape:SolidMolecular weight:701.47Luffariellolide
CAS:Luffariellolide is a terpene compound obtained from the marine sponge Hyrtios communis that is an HSF-PLA2 inhibitor and a RAR agonist.Formula:C25H38O3Purity:98%Color and Shape:SolidMolecular weight:386.57SJF 8240
CAS:c-MET degrader with foretinib linked to VHL ligand; reduces c-MET in 6h, hampers AKT, halts GTL16 cells (IC50=66.7nM), acts on exon-14-less c-MET.
Formula:C58H65F2N7O11SColor and Shape:SolidMolecular weight:1106.25INCB-9471 dihydrochloride
CAS:INCB-9471 HCl: a potent CCR5 antagonist, blocks monocyte migration & HIV-1.Formula:C30H42Cl2F3N5O2Purity:98%Color and Shape:SolidMolecular weight:632.59RU 52583
CAS:RU 52583 is an alpha 2-adrenergic receptor antagonist.Formula:C18H20N2Purity:98%Color and Shape:SolidMolecular weight:264.36ATM-3507 trihydrochloride (1861449-70-8 free base)
ATM-3507 trihydrochloride is a potent tropomyosin inhibitor (IC50s: 3.83-6.84 μM in human melanoma cell lines).Formula:C37H49Cl3FN5O2Purity:98%Color and Shape:SolidMolecular weight:721.17Tofogliflozin
CAS:Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).Formula:C22H26O6Purity:98%Color and Shape:SolidMolecular weight:386.44GR 122222X
CAS:GR 122222X is an inhibitor of topoisomerase II.Formula:C26H35N5O11SPurity:98%Color and Shape:SolidMolecular weight:625.65CE-2072
CAS:CE-2072 is a synthetic host serine proteases inhibitor.Formula:C33H41N5O6Purity:98%Color and Shape:SolidMolecular weight:603.71CHNQD-01255
CAS:CHNQD-01255 is an orally active inhibitor of Arf-GEFs that is effective against hepatocellular carcinoma (HCC).Formula:C23H29NO6Color and Shape:SolidMolecular weight:415.48BTK-IN-16
CAS:BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.Formula:C15H14N4O2Purity:99.04%Color and Shape:SoildMolecular weight:282.3Gimatecan
CAS:Gimatecan (STI481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.Formula:C25H25N3O5Purity:98.47%Color and Shape:SolidMolecular weight:447.48
