Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,876 products)
- Chromatin/Epigenetics(2,613 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,015 products)
- Immunology and Inflammation(3,901 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,137 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,414 products)
- Other Inhibitors(35,849 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66517 products of "Inhibitors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
PARP10/15-IN-2
CAS:PARP10/15-IN-2 (Compound 8h) blocks PARP10/15, has IC50s: 0.15μM/0.37μM, cell-permeable, prevents apoptosis.Formula:C15H11FN2O3Color and Shape:SolidMolecular weight:286.26E 5090
CAS:E5090 is a novel orally active inhibitor of IL-1 generation. It also has anti-inflammatory properties.Formula:C19H20O5Purity:98%Color and Shape:SolidMolecular weight:328.36MsbA-IN-2
MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).Formula:C23H19Cl2NO3Color and Shape:SolidMolecular weight:428.31Salacinol
CAS:Salacinol is a naturally occurring alpha-glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata.Formula:C9H18O9S2Color and Shape:SolidMolecular weight:334.37PROTAC CDK12/13 Degrader-1
PROTAC CDK12/13 Degrader-1 (7f) selectively degrades CDK12/13 at nanomolar potency, targeting breast cancer.Color and Shape:SolidLasonolide A
CAS:Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.Formula:C41H60O9Color and Shape:SolidMolecular weight:696.91P-gp modulator 3
P-gp modulator 3 (Compound 37) is a potent, competitive, metabotropic P-glycoprotein (P-gp) modulator.Formula:C31H37N3O5Color and Shape:SolidMolecular weight:531.64T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Formula:C36H39FN4OSColor and Shape:SolidMolecular weight:594.78GDC-0927 Racemate
CAS:GDC-0927 Racemate is a degrader of estrogen receptor, is used in the research of ER-related diseases, potently inhibits ER-α activity, with an IC50 of 0.2 nM.Formula:C28H28FNO4Purity:98%Color and Shape:SolidMolecular weight:461.52HDAC10-IN-1
HDAC10-IN-1 is a potent, selective HDAC10 inhibitor (IC50=58 nM) affecting autophagy in FLT3-ITD+ acute myeloid leukemia cells.Formula:C18H23N3O2Color and Shape:SolidMolecular weight:313.39VEGFR-2-IN-26
CAS:VEGFR-2-IN-26 inhibits VEGFR-2 (IC50: 15.5 nM), combating various cancers' cell growth.Formula:C24H19F3N6O2Color and Shape:SolidMolecular weight:480.44Antifungal agent 13
CAS:Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Formula:C21H16ClF3N4OColor and Shape:SolidMolecular weight:432.83MK-1220
CAS:MK-1220 is a novel Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure.Formula:C40H53N5O9SColor and Shape:SolidMolecular weight:779.94CK156
CAS:CK156 inhibits DAPK with high selectivity; IC50: 182 nM (DRAK1), 34 μM (CK2a1), 39 μM (CK2a2); key in autoimmune/inflammation research.Formula:C21H25N5O3Color and Shape:SolidMolecular weight:395.45Faldaprevir sodium
CAS:Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.Formula:C40H48BrN6NaO9SColor and Shape:SolidMolecular weight:891.81Anticancer agent 30
Anticancer agent 30 (6f-Z), a 3-arylidene-2-oxindole, selectively inhibits CDK2, showing potent anticancer potential.Formula:C22H15ClFNOColor and Shape:SolidMolecular weight:363.81NBTIs-IN-4
NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.Formula:C22H24FN5O5SColor and Shape:SolidMolecular weight:489.52RAD51-IN-7
CAS:RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)Formula:C25H31N5O4S2Color and Shape:SolidMolecular weight:529.67ML-SI1
CAS:ML-SI1, a racemic mixture of diastereoisomers, is a TRPML inhibitor and acts on TRPML1 (IC50: 15 μM).Formula:C23H26Cl2N2O3Color and Shape:SolidMolecular weight:449.37Rivenprost
CAS:Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.Formula:C24H34O6SColor and Shape:SolidMolecular weight:450.59JTP-117968
CAS:JTP-117968: Non-steroidal SGRM, glucocorticoid receptor modulator, IC50 = 6.8 nM, offers better inhibitory/activatory balance.Formula:C31H31F3N2O2Color and Shape:SolidMolecular weight:520.59Oncopterin
CAS:Oncopterin is found in urine from patients with solid and blood cancers.Formula:C12H18N6O3Color and Shape:SolidMolecular weight:294.31Mopivabil
Mopivabil is the angiotensin II receptor antagonist[1].Formula:C14H20O3Color and Shape:SolidMolecular weight:236.31MK-7128
CAS:MK-7128 is a CB1 receptor inverse agonist.Formula:C29H25ClF2N4O2Color and Shape:SolidMolecular weight:534.98COX-2-IN-13
COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.Formula:C19H18N2O5SColor and Shape:SolidMolecular weight:386.42CDK7/12-IN-1
CAS:CDK7/12-IN-1 is a selective CDK7 (IC50: 3 nM) and CDK12 (IC50: 277 nM) inhibitor, effective against tumor growth.Formula:C25H34N8OColor and Shape:SolidMolecular weight:462.59Isoleucyl tRNA synthetase-IN-1
CAS:Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS).Formula:C23H35N5O7SColor and Shape:SolidMolecular weight:525.62Aeruginosin 98-B
CAS:Aeruginosin 98-B, a protease inhibitor, effectively inhibits trypsin, plasmin, and thrombin with IC50 values of 0.6, 7.0, and 10.0 μg/mL, respectively.Formula:C29H46N6O9SColor and Shape:SolidMolecular weight:654.78Lp-PLA2-IN-6
CAS:Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.Formula:C25H21F5N4O3Color and Shape:SolidMolecular weight:520.45Nnc 09-0026
CAS:Nnc 09-0026 is a neuronal calcium channel blockerFormula:C25H35Cl2F3N2OColor and Shape:SolidMolecular weight:507.46COX-2-IN-10
COX-2-IN-10 is a potent COX-2 inhibitor, reducing IL-6, TNF-α, IL-1β, PGE2 (IC50=2.54 μM), and iNOS expression.Formula:C31H32FN5O2SColor and Shape:SolidMolecular weight:557.68Tetrahydrouridine dihydrate
THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.Formula:C9H20N2O8Color and Shape:SolidMolecular weight:284.26CXCR2 antagonist 7
CXCR2 antagonist 7 is a powerful blocker with IC50s: 0.044 μM for binding, 0.66 μM for calcium mobilization.Formula:C14H14F2N6OSColor and Shape:SolidMolecular weight:352.365-Ph-IAA-AM
5-Ph-IAA-AM, eggshell-permeable analog of 5-Ph-IAA, boosts protein degradation in embryos, useful for studying proteins in C. elegans.Formula:C19H17NO4Color and Shape:SolidMolecular weight:323.34Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Color and Shape:SolidMolecular weight:454.56HBV-IN-20
HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).Color and Shape:SolidVEGFR-2-IN-10
VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0.7 μM and no cytotoxic effects.Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4RdRP-IN-4
RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.Formula:C17H17Br2N3O2Color and Shape:SolidMolecular weight:455.14EBI-907
CAS:EBI-907 is a potent, oral B-RafV600E inhibitor with an IC50 of 4.9 nM, over 10x stronger than Vemurafenib, and effective against key cancer kinases.Formula:C23H21ClF2N4O3SColor and Shape:SolidMolecular weight:506.95SphK2-IN-1
CAS:SphK2-IN-1 is an SphK2 inhibitor with an IC50 value of 0.359 μM. SphK2-IN-1 can be used to study cancer, inflammation, neurological and cardiovascular diseases.Formula:C23H22ClF3N8OColor and Shape:SolidMolecular weight:518.92AN-12-H5
CAS:AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.Formula:C24H23N3O4S3Color and Shape:SolidMolecular weight:513.652',5,7-Trihydroxy-8-methoxyflavanone
CAS:2',5,7-Trihydroxy-8-methoxyflavanone has cytotoxic activity.Formula:C16H14O6Purity:98%Color and Shape:SolidMolecular weight:302.28BACE1-IN-4
CAS:BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.Formula:C21H23F2N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.57BIIE-0246 HCl
CAS:BIIE-0246: A potent, non-peptide Y2 receptor antagonist; >650-fold more selective than Y1, Y4, Y5.Formula:C49H59Cl2N11O6Color and Shape:SolidMolecular weight:968.97EGFR-IN-23
CAS:EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.Formula:C36H44BrN10O3PColor and Shape:SolidMolecular weight:775.68Thielavin B
CAS:Thielavin B, from Thielavia terricola, inhibits prostaglandin E2 synthesis and reduces rat oedema.Formula:C31H34O10Color and Shape:SolidMolecular weight:566.6hMAO-B/MB-COMT-IN-1
Dual hMAO-B/MB-COMT inhibitor, IC50: 2.5 μΜ (hMAO-B), 3.84 μΜ (MB-COMT); potential in Parkinson's research.Formula:C16H19NO3Color and Shape:SolidMolecular weight:273.33Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Formula:C16H25N7O8Color and Shape:SolidMolecular weight:443.41MRS4458
CAS:MRS4458 is an effective inhibitor of the P2Y14 Receptor.Formula:C24H20F3N5O3SPurity:98%Color and Shape:SolidMolecular weight:515.51BMS-986118
CAS:BMS-986118 is a GPR40 full agonist targeting type II diabetes, prompting insulin release without hypoglycemia risk.Formula:C25H28ClF3N4O4Purity:98%Color and Shape:SolidMolecular weight:540.96
