Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,015 products)
- Immunology and Inflammation(3,901 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,153 products)
- Metabolism(10,140 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,405 products)
- Other Inhibitors(35,850 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66518 products of "Inhibitors"
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RET-IN-9
CAS:RET-IN-9 is a potent RET kinase inhibitor, potentially useful for studying RET-related diseases, including lung and thyroid cancer.Formula:C26H27N9OColor and Shape:SolidMolecular weight:481.55BIIE-0246 HCl
CAS:BIIE-0246: A potent, non-peptide Y2 receptor antagonist; >650-fold more selective than Y1, Y4, Y5.Formula:C49H59Cl2N11O6Color and Shape:SolidMolecular weight:968.97MK-7128
CAS:MK-7128 is a CB1 receptor inverse agonist.Formula:C29H25ClF2N4O2Color and Shape:SolidMolecular weight:534.98EGFR-IN-23
CAS:EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.Formula:C36H44BrN10O3PColor and Shape:SolidMolecular weight:775.68FTI-2148
CAS:FTI-2148 blocks RAS-related FT-1 & GGT-1; IC50: 1.4 nM & 1.7 μM.Formula:C24H28N4O3SPurity:98%Color and Shape:SolidMolecular weight:452.57G-4120
CAS:G-4120 is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis.Formula:C26H36N8O11SColor and Shape:SolidMolecular weight:668.68IDO1-IN-14
IDO1-IN-14 is an IDO1 enzyme inhibitor with an IC50 of 396.9 nM and suppresses HeLa cell activity with an EC50 of 3393 nM.Formula:C18H12Cl2FN3O2Color and Shape:SolidMolecular weight:392.21BMS-986118
CAS:BMS-986118 is a GPR40 full agonist targeting type II diabetes, prompting insulin release without hypoglycemia risk.Formula:C25H28ClF3N4O4Purity:98%Color and Shape:SolidMolecular weight:540.96Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Formula:C16H25N7O8Color and Shape:SolidMolecular weight:443.41VEGFR-2-IN-10
VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0.7 μM and no cytotoxic effects.Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4Fandosentan
CAS:Fandosentan is an endothelin receptor antagonist.Formula:C25H18F3NO6SColor and Shape:SolidMolecular weight:517.47Antileishmanial agent-6
Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.Formula:C24H26O8Color and Shape:SolidMolecular weight:442.46Mopivabil
Mopivabil is the angiotensin II receptor antagonist[1].Formula:C14H20O3Color and Shape:SolidMolecular weight:236.31B026
CAS:B026: Oral p300/CBP HAT inhibitor, IC50: p300 1.8 nM, CBP 9.5 nM; targets AR+ prostate cancer cells.Formula:C27H23F4N5O4Color and Shape:SolidMolecular weight:557.5BACE1-IN-4
CAS:BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.Formula:C21H23F2N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.57AZ12971554
AZ12971554: Human thrombin inhibitor, Ki=0.3nM; APTT IC50=0.68µM; ECT IC50=0.16µM.Formula:C20H17ClFN7O3Color and Shape:SolidMolecular weight:457.85Anticancer agent 69
Anticancer agent 69 targets PC3 cells (IC50=26 nM), raises ROS, lowers EGFR, and induces apoptosis.Formula:C19H26N8SColor and Shape:SolidMolecular weight:398.53Ciluprevir
CAS:Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.Formula:C40H50N6O8SPurity:98%Color and Shape:SolidMolecular weight:774.93TIY-7
TIY-7 is a selective, orally active inhibitor of the promyosin receptor kinase (TRK) enzyme. TIY-7 exhibited anti-tumour effects in a mouse xenograft model.Color and Shape:SolidKDM1/CDK1-IN-1
KDM1/CDK1-IN-1 inhibits KDM1 (IC50: 0.096 μM) & CDK1 (IC50: 0.078 μM), blocks HOP-92 G2/M phase, induces apoptosis, toxic to cancer cells.Formula:C22H17N5O3SColor and Shape:SolidMolecular weight:431.47MCTR2
CAS:MCTR2, synthesized from DHA in macrophages, aids in tissue repair and reduces inflammation by promoting eicosanoid PGD2 and PGF2α decrease.Formula:C27H40N2O6SColor and Shape:SolidMolecular weight:520.68Cbl-b-IN-2
CAS:Cbl-b-IN-2 is an oral E3 enzyme inhibitor for immune-modulated diseases and cancer research.Formula:C29H30F5N5O2Color and Shape:SolidMolecular weight:575.57PF-446687
CAS:PF-446687 is a highly selective MC4 receptor (MC4R) agonist.Formula:C28H37ClF2N2O2Color and Shape:SolidMolecular weight:507.06Protopine hydrochloride
CAS:Protopine inhibits thromboxane, lowers intracellular calcium, and reduces cell adhesion by altering adhesive factors.Formula:C20H20ClNO5Purity:98%Color and Shape:Prisms From Alc SolidMolecular weight:389.83Tzc 5665
CAS:Tzc 5665 is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory action.Formula:C31H38ClN5O7Color and Shape:SolidMolecular weight:628.12MRS4458
CAS:MRS4458 is an effective inhibitor of the P2Y14 Receptor.Formula:C24H20F3N5O3SPurity:98%Color and Shape:SolidMolecular weight:515.51AMG-369
CAS:AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.Formula:C26H22FN3O2SPurity:98.04% - 98.92%Color and Shape:SolidMolecular weight:459.54NK-1 Antagonist 1
CAS:NK-1 Antagonist 1 is a NK-1 receptor antagonist.Formula:C25H23F6N5O2Purity:98%Color and Shape:SolidMolecular weight:539.47Lapaquistat
CAS:Lapaquistat: active TAK-475 metabolite; reduces cholesterol synthesis and statin myotoxicity.Formula:C31H39ClN2O8Purity:98%Color and Shape:SolidMolecular weight:603.1ONO-9780307
CAS:ONO-9780307 is a specific antagonist of LPA1 (lysophosphatidic acid receptor 1) (IC50: 2.7 nM).Formula:C30H35NO7Color and Shape:SolidMolecular weight:521.6(-)-Adenophorine
CAS:(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.Formula:C8H17NO4Color and Shape:SolidMolecular weight:191.22Lisuride
CAS:Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.Formula:C20H26N4OColor and Shape:SolidMolecular weight:338.45(S)-Purvalanol B
CAS:(S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is an inhibitor of cyclin-dependent kinase(CDK) .Formula:C20H25ClN6O3Purity:98%Color and Shape:SolidMolecular weight:432.92',5,7-Trihydroxy-8-methoxyflavanone
CAS:2',5,7-Trihydroxy-8-methoxyflavanone has cytotoxic activity.Formula:C16H14O6Purity:98%Color and Shape:SolidMolecular weight:302.28Monoamine Oxidase B inhibitor 2
MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.Formula:C19H19FO3Color and Shape:SolidMolecular weight:314.35VEGFR-2/DHFR-IN-1
Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.Formula:C20H18ClNO4Color and Shape:SolidMolecular weight:371.81Motuporin
CAS:Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).Formula:C40H57N5O10Color and Shape:SolidMolecular weight:767.91Lp-PLA2-IN-6
CAS:Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.Formula:C25H21F5N4O3Color and Shape:SolidMolecular weight:520.45TRPC4/5-IN-1
TRPC4/5-IN-1, a TRPC5/4 inhibitor with IC50s 0.54 μM/2.06 μM, targets skin inflammation and proteinuric kidney diseases.Formula:C21H21N3OColor and Shape:SolidMolecular weight:331.41Anticancer agent 29
Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).Formula:C22H15ClFNOColor and Shape:SolidMolecular weight:363.81Cacospongionolide B
CAS:Cacospongionolide B from Fasciospongia cavernosa inhibits secretory phospholipase A2, curbing inflammation.Formula:C25H36O4Color and Shape:SolidMolecular weight:400.55IDX-320
CAS:IDX-320 is an HCV protease inhibitor.Formula:C37H43F3N6O7S2Color and Shape:SolidMolecular weight:804.9LSD1-IN-17
LSD1-IN-17, a potent LSD1/CoREST/MAO inhibitor, IC50: 0.005/0.028/0.820 μM; hinders LNCaP prostate cancer cell growth, IC50: 17.2 μM.Formula:C20H18N2OSColor and Shape:SolidMolecular weight:334.43LY 292728
CAS:LY 292728 is a highly potent antagonist of leukotriene B4 receptor.Formula:C34H29FO9Purity:98%Color and Shape:SolidMolecular weight:600.59Balanol
CAS:Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.Formula:C28H26N2O10Color and Shape:SolidMolecular weight:550.51HBV-IN-20
HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).Color and Shape:SolidEBI-907
CAS:EBI-907 is a potent, oral B-RafV600E inhibitor with an IC50 of 4.9 nM, over 10x stronger than Vemurafenib, and effective against key cancer kinases.Formula:C23H21ClF2N4O3SColor and Shape:SolidMolecular weight:506.95Laulimalide
CAS:Microtubule stabilizer; halts cancer cell growth (IC50: 3-30 nM); arrests cells in prometaphase; prevents bipolar spindle formation.Formula:C30H42O7Color and Shape:SolidMolecular weight:514.65LXRβ agonist-2
CAS:LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM.Formula:C32H31F6N3O7Purity:98%Color and Shape:SolidMolecular weight:683.59TLR7/8 agonist 7
CAS:TLR7/8 agonist 7 activates immune cells, useful in ISAC synthesis and immunity research.Formula:C26H37N7O2Color and Shape:SolidMolecular weight:479.62
