Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,901 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,377 products)
- Other Inhibitors(35,852 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,430 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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Epolactaene
CAS:Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.Formula:C21H27NO6Color and Shape:SolidMolecular weight:389.44NA 0362
CAS:NA 0362 is a derivative of SF 2370 that inhibits smooth muscle contraction.Formula:C28H26N4O4Color and Shape:SolidMolecular weight:482.53GAT564
GAT564, an allosteric CB1R modulator, shows EC50s of 87 nM (cAMP) & 320 nM (β-arrestin2) and lowers IOP effectively in glaucoma mice.Formula:C20H16N2O2SColor and Shape:SolidMolecular weight:348.42AMG-315
CAS:AMG-315: Chiral AEA analogue, potent CB1 agonist (Ki 7.8 nM, EC50 0.6 nM), stable against hydrolyzing/oxidative enzymes.Formula:C24H41NO2Color and Shape:SolidMolecular weight:375.5922-HDHA
CAS:22-HDHA is an oxidation product of docosahexaenoic acid .Formula:C22H32O3Color and Shape:SolidMolecular weight:344.49KRAS G12D inhibitor 12
KRAS G12D inhibitor 12 targets Ras protein for cancer research. (Patent WO2021108683A1, Compound 134)Formula:C23H21ClFN5O3Color and Shape:SolidMolecular weight:469.9TRPC4/5-IN-1
TRPC4/5-IN-1, a TRPC5/4 inhibitor with IC50s 0.54 μM/2.06 μM, targets skin inflammation and proteinuric kidney diseases.Formula:C21H21N3OColor and Shape:SolidMolecular weight:331.41BTK-IN-15
BTK-IN-15: Oral BTK inhibitor, IC50 0.7 nM, induces cancer cell apoptosis, selective with anti-tumor effects.Formula:C28H24FN5O2Color and Shape:SolidMolecular weight:481.52Antibacterial agent 78
Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].Formula:C16H23N3S2Color and Shape:SolidMolecular weight:321.5Sargachromanol E
CAS:Sargachromanol E is a compound isolated from the marine brown alga, Sargassum horneri. It has been studied for its inhibitory effect on skin ageing.Formula:C27H40O4Color and Shape:SolidMolecular weight:428.6LPM4870108
LPM4870108: Potent, oral pan-Trk inhibitor, selective over ALK, with anti-tumor effects. TrkC IC50=0.2nM, TrkA IC50=2.4nM.Formula:C20H19FN6O3Color and Shape:SolidMolecular weight:410.4Rafutrombopag
CAS:Rafutrombopag is a thrombopoietin (TPO) agonist.Formula:C25H22N4O5Color and Shape:SolidMolecular weight:458.47Asimicin
CAS:Asimicin is a effective complex I inhibitor.Formula:C37H66O7Purity:98%Color and Shape:SolidMolecular weight:622.92METTL3-IN-2
CAS:METTL3-IN-2, a potent METTL3 inhibitor, exhibits an IC50 value of 6.1 nM, effectively impairing the proliferation of Caov3 cancer cells.Formula:C25H26N8OColor and Shape:SolidMolecular weight:454.53PARP10/15-IN-3
Compound 8a, a dual PARP10 & PARP15 inhibitor, has IC50s: PARP10 at 0.14μM & PARP15 at 0.40μM; it's cell-permeable & anti-apoptotic.Formula:C12H12N2O3Color and Shape:SolidMolecular weight:232.24Anticancer agent 12
Anticancer agent 12 shows cytotoxic activity in malignant cells with no hepatotoxicity.Formula:C16H17BrN4O2SColor and Shape:SolidMolecular weight:409.3MRS2279
CAS:Selective, high affinity competitive antagonist of the P2Y1 receptorFormula:C13H18ClN5O8P2Purity:98%Color and Shape:SolidMolecular weight:469.71BCL6-IN-9
CAS:BCL6-IN-9 (compound 1) is a potent inhibitor of B-cell lymphoma 6 protein (BCL6) (IC50: 3.9 nM) and can be used to study cancer.Formula:C22H18ClF2N5O2Color and Shape:SolidMolecular weight:457.86Anti-inflammatory agent 10
Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.Formula:C17H13BrN4O3S2Color and Shape:SolidMolecular weight:465.34Aβ-IN-2
Aβ-IN-2 is a peptide inhibitor of Aβ1-42.Formula:C37H51NOColor and Shape:SolidMolecular weight:525.81Protopine hydrochloride
CAS:Protopine inhibits thromboxane, lowers intracellular calcium, and reduces cell adhesion by altering adhesive factors.Formula:C20H20ClNO5Purity:98%Color and Shape:Prisms From Alc SolidMolecular weight:389.83AK-295
CAS:AK 295, also known as CX 295, is a dipeptide inhibitor of alpha-ketoamide calpain.Formula:C26H40N4O6Color and Shape:SolidMolecular weight:504.62Sdz 210-096
CAS:Sdz 210-096: a 14 beta-benzyl morphinan, mu/kappa opiate receptor antagonist, stimulates LH secretion in rats.Formula:C27H31NO2Color and Shape:SolidMolecular weight:401.54DGY-08-097
CAS:DGY-08-097: potent HCV NS3 degrader, low resistance risk, strong inhibition in cells, DC50 of 50nM at 4h.Formula:C60H76N10O14Color and Shape:SolidMolecular weight:1161.3CYP2C19-IN-1
CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.Formula:C26H26N2O6SColor and Shape:SolidMolecular weight:494.56JAK2 JH2 binder-1
CAS:JAK2 JH2 binder-1: potent, selective, Ki=37.1 nM, potential for studying myeloproliferative neoplasms.Formula:C29H25N7O6SColor and Shape:SolidMolecular weight:599.62CCW 28-3
CAS:CCW 28-3 is a novel potent covalent BRD4 degrader, degrading BRD4 in a proteasome- and RNF4-dependent manner without inhibiting RNF4 autoubiquitination activityFormula:C44H42Cl2N6O4SColor and Shape:SolidMolecular weight:821.81MI-1851
CAS:MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.Formula:C34H53N15O6Color and Shape:SolidMolecular weight:767.88Cilengitide hydrochloride
CAS:Cilengitide hydrochloride is a salt that may combat cancer by blocking specific integrins, disrupting cell interactions and angiogenesis.Formula:C27H41ClN8O7Color and Shape:SolidMolecular weight:625.12Saussureamine C
CAS:Saussureamine C is an inhibitor of H274Y and N294S mutants.Formula:C19H26N2O5Color and Shape:SolidMolecular weight:362.42Leukotriene F4
CAS:LTF4, made in vitro from LTE4 with enzymes, contracts vascular muscle weakly; potency is LTD4 > LTC4 > LTE4 >> LTF4.Formula:C28H44N2O8SColor and Shape:SolidMolecular weight:568.72Lp-PLA2-IN-6
CAS:Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.Formula:C25H21F5N4O3Color and Shape:SolidMolecular weight:520.45GSK-3β inhibitor 7
GSK-3β inhibitor 7 is a GSK-3β inhibitor (IC50: 5.25 μM).Formula:C27H23BrN4O2SColor and Shape:SolidMolecular weight:547.47Antimalarial agent 3
Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.Formula:C15H16BrN3O2Color and Shape:SolidMolecular weight:350.21AL-GDa62
AL-GDa62, a gastric cancer treatment lead, has EC50 of 3.2 μM (MCF10A-WT) and 2 μM (MCF10A-CDH1 -/-).Formula:C24H28FN3OColor and Shape:SolidMolecular weight:393.5ATM Inhibitor-3
ATM Inhibitor-3 selectively inhibits ATM (IC50: 0.71 nM), targets PI3K kinase family, and is metabolically stable.Formula:C25H29FN6O3Color and Shape:SolidMolecular weight:480.53TK-129
TK-129: Oral KDM5B inhibitor, IC50=44 nM, low-toxicity, cardioprotective, aids in heart disease research.Formula:C15H23N5O2Color and Shape:SolidMolecular weight:305.38HIV-1 inhibitor-52
CAS:HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.Formula:C46H72FNO5SColor and Shape:SolidMolecular weight:770.13KRAS G12C inhibitor 20
CAS:KRAS G12C inhibitor 20 is a KRAS G12C inhibitor.Formula:C33H37ClFN7O3Color and Shape:SolidMolecular weight:634.14GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Formula:C28H32F3N5O4Color and Shape:SolidMolecular weight:559.58Tylophorinidine
CAS:Tylophorinidine is an antifungal agent that has shown to inhibit cell growth.Formula:C22H23NO4Color and Shape:SolidMolecular weight:365.42Basroparib
CAS:Basroparib is an inhibitor of ribose polymerase (PARP) and has shown antitumour effects.Formula:C18H21F2N7O3Color and Shape:SolidMolecular weight:421.4BTK-IN-16
CAS:BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.Formula:C15H14N4O2Purity:99.04%Color and Shape:SoildMolecular weight:282.3FGFR4-IN-6
FGFR4-IN-6: covalent, reversible FGFR4 blocker, 5.4 nM IC50, good oral bioavailability, reduces Hep3B2.1-7 tumors in mice, low toxicity.Formula:C31H33N7O4Color and Shape:SolidMolecular weight:567.64Anticancer agent 54
Anticancer agent 54 blocks cell cycle in G0/G1, induces apoptosis, and fights cancer via DNA embedding and ROS.Formula:C33H36N6Color and Shape:SolidMolecular weight:516.68RAD51-IN-8
RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.Formula:C16H14Cl2FN3O2Color and Shape:SolidMolecular weight:370.21DS01080522
DS01080522: PRKACA inhibitor, IC50: kinase 0.8 nM, CREB 66 nM; potential for cancer research.Formula:C23H20Cl2N4O3Color and Shape:SolidMolecular weight:471.34BACE1-IN-2
CAS:BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).Formula:C19H15F4N5O2Purity:98%Color and Shape:SolidMolecular weight:421.35CI 992
CAS:CI 992 is a novel potent inhibitor of primate renin.Formula:C33H52N6O7S2Color and Shape:SolidMolecular weight:708.93PRMT5-IN-1
CAS:PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50 of 11 nM for PRMT5/MEP50).Formula:C19H19ClN4O5Purity:98%Color and Shape:SolidMolecular weight:418.83
