Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,015 products)
- Immunology and Inflammation(3,901 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,153 products)
- Metabolism(10,140 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,405 products)
- Other Inhibitors(35,850 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66518 products of "Inhibitors"
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PD-1/PD-L1-IN-15
PD-1/PD-L1-IN-15 is a potent inhibitor of PD-1/PD-L1 (IC50: 60.1 nM) and has shown investigational potential for tumor immunotherapy.Formula:C32H30N4O3Color and Shape:SolidMolecular weight:518.61HbF inducer-1
HbF inducer-1 is a fetal hemoglobin inducer which is orally bioavailable.Formula:C18H19N3O3Color and Shape:SolidMolecular weight:325.36Fluperolone acetate
CAS:Fluperolone acetate is a Glucocorticoid/Adrenal Cortex Hormone.
Formula:C24H31FO6Color and Shape:SolidMolecular weight:434.50Gimatecan
CAS:Gimatecan (STI481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.Formula:C25H25N3O5Purity:98.47%Color and Shape:SolidMolecular weight:447.48Steroid sulfatase/17β-HSD1-IN-1
Steroid sulfatase/17β-HSD1-IN-1 is a highly effective inhibitor of both steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) activities,Formula:C19H18N2O5SColor and Shape:SolidMolecular weight:386.42Antiproliferative agent-8
Compound 5a, an anticancer agent, enhances P53 and has antiproliferative effects.Formula:C22H16ClN3O3Color and Shape:SolidMolecular weight:405.83PI3K-IN-27
CAS:PI3K-IN-27 is a potent PI3K inhibitor, relevant for cancer and immune disease research. See patent WO2021233227A1.Formula:C30H26F2N6O2SColor and Shape:SolidMolecular weight:572.63GR 122222X
CAS:GR 122222X is an inhibitor of topoisomerase II.Formula:C26H35N5O11SPurity:98%Color and Shape:SolidMolecular weight:625.65Antimalarial agent 2
Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.Formula:C27H25N3O5Color and Shape:SolidMolecular weight:471.5Tofogliflozin
CAS:Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).Formula:C22H26O6Purity:98%Color and Shape:SolidMolecular weight:386.44LSD1/2-IN-3
LSD1/2-IN-3 selectively inhibits LSD1 (Ki 11 nM) over LSD2 (Ki 7 μM), and hinders tumor stem cell proliferation.Formula:C9H8BrF2NColor and Shape:SolidMolecular weight:248.07Antibacterial agent 78
Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].Formula:C16H23N3S2Color and Shape:SolidMolecular weight:321.5Ph-Ph+
Ph-Ph+ is a dimerized phenanthroline derivative with antitumor, antibacterial, and antifungal effects.Formula:C24H17N4Color and Shape:SolidMolecular weight:361.42EGFR/HER2-IN-6
EGFR/HER2-IN-6 is a dual inhibitor of EGFR, HER2, and DHFR with IC50s: 0.122, 0.078, and 0.585 μM, showing anticancer potential and selectivity.Formula:C18H21N5O3SColor and Shape:SolidMolecular weight:387.46RIPK1-IN-14
CAS:RIPK1-IN-14 inhibits RIPK1 with 92 nM IC50 and reduces necrotic apoptosis in U937 cells.Color and Shape:Soild(2S,4S)-Sacubitril
CAS:(2S,4S)-Sacubitril (Sacubitril Impurity C) is a stereoisomer derived from Sacubitril which is a potent NEP inhibitor.Formula:C24H29NO5Purity:98%Color and Shape:SolidMolecular weight:411.49COX-2-IN-13
COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.Formula:C19H18N2O5SColor and Shape:SolidMolecular weight:386.42AN-12-H5
CAS:AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.Formula:C24H23N3O4S3Color and Shape:SolidMolecular weight:513.65Complex III-IN-1
Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.Formula:C14H20ClNO2S2Color and Shape:SolidMolecular weight:333.9Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Color and Shape:SolidMolecular weight:454.56Verrucarin A
CAS:Verrucarin A, a mycotoxin from Myrothecium verrucaria, inhibits protein synthesis, leukemia growth, and triggers apoptosis.Formula:C27H34O9Color and Shape:SolidMolecular weight:502.55PF-07054894
CAS:PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.Formula:C24H30N6O4Color and Shape:SolidMolecular weight:466.53Nipradolol
CAS:Nipradolol blocks alpha-1-adrenergic receptors, lowers IOP in rabbits, and reduces NA-induced muscle contraction and dog artery vasodilation.Formula:C15H22N2O6Color and Shape:SolidMolecular weight:326.35SGK1-IN-3
CAS:SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.Formula:C23H20Cl2N6O3SColor and Shape:SolidMolecular weight:531.414JAK3-IN-7
CAS:JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction afterFormula:C17H20N6OPurity:98.81%Color and Shape:SolidMolecular weight:324.38LAS195319
CAS:LAS195319 is a potent and selective inhaled PI3Kδ Inhibitor (IC50 = 0.5 nM) for the Treatment of Respiratory Diseases.Formula:C29H26N10O3SColor and Shape:SolidMolecular weight:594.65EGFR/HER2-IN-8
EGFR/HER2-IN-8 inhibits EGFR, HER2, DHFR (IC50: 0.45, 0.244, 5.669 μM); useful in cancer research, safe and selective.Formula:C16H16N4O2SColor and Shape:SolidMolecular weight:328.39Antitumor agent-51
Antitumor agent-51 targets osteosarcoma with 21.9 nM IC50, high selectivity, and low toxicity.Formula:C23H25N5O2SColor and Shape:SolidMolecular weight:435.54DNA crosslinker 1 dihydrochloride
CAS:DNA Crosslinker 1 binds DNA minor groove with 1.1°C affinity increase; used in cancer research.Formula:C15H22Cl2N8OColor and Shape:SolidMolecular weight:401.29ALK5-IN-7
CAS:ALK5-IN-7 inhibits ALK5, useful in TGF-β disease research like cancer, fibrosis, and autoimmune disorders. See WO2021129621A1.Formula:C26H28N4O3SColor and Shape:SolidMolecular weight:476.59CXCR2 antagonist 7
CXCR2 antagonist 7 is a powerful blocker with IC50s: 0.044 μM for binding, 0.66 μM for calcium mobilization.Formula:C14H14F2N6OSColor and Shape:SolidMolecular weight:352.36AP5
CAS:AP5: GPR40 agonist, positive allosteric modulator; rat hIP1 EC50: 0.49 nM.Formula:C28H28FNO4Purity:98%Color and Shape:SolidMolecular weight:461.52N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].Formula:C11H9FN4OColor and Shape:SolidMolecular weight:232.21PNU-140457
CAS:PNU-140457 is a bio-active chemical.Formula:C14H14FN5O3Color and Shape:SolidMolecular weight:319.29Cicaprost
CAS:Cicaprost (ZK 96480) is an IP agonist with artery relaxing effects; EC50 is 5.8 nM.Formula:C22H30O5Color and Shape:SolidMolecular weight:374.47Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.Formula:C23H27N3O2SColor and Shape:SolidMolecular weight:409.54A25822B
CAS:A25822B is an antifungal agent.Formula:C28H45NOPurity:98%Color and Shape:SolidMolecular weight:411.66TSWV-IN-1
TSWV-IN-1 is an anti-TSWV drug with potential TSWV N.Formula:C26H31FO4S2Color and Shape:SolidMolecular weight:490.65C5aR-IN-3
CAS:C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.Formula:C36H40FN5O3Color and Shape:SolidMolecular weight:609.73Mcl-1 inhibitor 9
CAS:Mcl-1 Inhibitor 9 (Example 2) is a potent inhibitor of myeloid cell leukemia 1 (Mcl-1), demonstrating anti-tumor activity with an IC50 value of 0.21889 nM.Formula:C32H39ClN2O5SColor and Shape:SolidMolecular weight:599.18p38 MAPK-IN-3
Compound 2c is a potent p38α MAPK inhibitor with antitumor effects, enhancing apoptosis and ROS.Formula:C22H17BrO2Color and Shape:SolidMolecular weight:393.27SENP2-IN-1
CAS:SENP2-IN-1 selectively inhibits SENP2, SENP1, and SENP5 with low IC50 values; useful in cancer studies.Formula:C32H29N3O5S2Color and Shape:SolidMolecular weight:599.72eIF4A3-IN-6
CAS:eIF4A3-IN-6 is a potent eIF4A inhibitor, potentially used for treating eIF4A-related diseases like cancer. (US20170145026A1)Formula:C26H25N3O5Color and Shape:SolidMolecular weight:459.49GS-9160
CAS:GS-9160 is a novel and potent inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase (IN) that specifically targets the process of strand transfer.Formula:C20H18FN3O4SColor and Shape:SolidMolecular weight:415.44FK-906 HCl
CAS:FK-906 HCl is a human renin inhibitor used for the long-term treatment of patients with essential hypertension.Formula:C40H64ClN7O7Color and Shape:SolidMolecular weight:790.44PDE4-IN-12
PDE4-IN-12 is a potent and safe PDE4 ubiquitous inhibitor that acts on PDE4 (IC50: 3.5 nM, SI: 2.71) and PDE7 (IC50: 15 nM, SI: 4.27).Formula:C34H35NO6Color and Shape:SolidMolecular weight:553.64LasR-IN-2
LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.Formula:C21H16ClN3O2Color and Shape:SolidMolecular weight:377.82MsbA-IN-5
MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.Formula:C23H19Cl2N5OColor and Shape:SolidMolecular weight:452.34Pol I-IN-1
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibitionFormula:C23H22N4O2Color and Shape:SolidMolecular weight:386.45Elacestrant S enantiomer dihydrochloride
Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.Formula:C30H40Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:531.56
