Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,852 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,430 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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TRPA1 Antagonist 1
CAS:TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.Formula:C24H20F6N5Na2O7PSPurity:98%Color and Shape:SolidMolecular weight:713.45EP4 receptor antagonist 2
CAS:EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor (IC50: 7.8 nM) and has antitumour effects.Formula:C27H29N3O5Color and Shape:SolidMolecular weight:475.54Omesdafexor
CAS:Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.Formula:C34H43N3O3Color and Shape:SolidMolecular weight:541.72Lasonolide A
CAS:Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.Formula:C41H60O9Color and Shape:SolidMolecular weight:696.91BMS-824
CAS:BMS-824: potent HCV NS5A inhibitor, IC50 ~5 nM, therapeutic index >10,000, specific to HCV.Formula:C27H25F3N4O5Color and Shape:SolidMolecular weight:542.515-HT6/5-HT2AR antagonist-1
Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.Formula:C21H26N6SColor and Shape:SolidMolecular weight:394.54LGB-321 HCl
CAS:LGB-321: potent, selective PIM kinase inhibitor, active against PIM2, halts diverse blood cancers' growth, orally effective in mice.Formula:C23H23ClF3N5O2Color and Shape:SolidMolecular weight:493.91LASSBio-1632
LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR & lung TNF-α, crosses BBB.Formula:C18H20N2O6SColor and Shape:SolidMolecular weight:392.43PXS-5153A monohydrochloride
CAS:PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 <40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.Formula:C20H25Cl2FN4O2SPurity:98%Color and Shape:Odour SolidMolecular weight:475.41AChE-IN-5
AChE-IN-5: oral, crosses blood-brain barrier, targets AChE/5-HT1A/SERT, potent with 2.29 nM IC50.Formula:C38H45N5OColor and Shape:SolidMolecular weight:587.8CXCR4 modulator-1
CAS:CXCR4 modulator-1 (ZINC72372983) is potent (EC50=100nM) with uses in anti-inflammatory, anticancer, and anti-HIV research.Formula:C23H27N5O2Color and Shape:SolidMolecular weight:405.49CaMKIIα-IN-1
CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.Formula:C14H11ClO4Color and Shape:SolidMolecular weight:278.69L-Afegostat
CAS:L-Afegostat (5-epi-Isofagomine), an iminosugar, inhibits glycosidase and β-Glucosidase (K i 30 μM), aids in carbohydrate synthesis.Formula:C6H13NO3Color and Shape:SolidMolecular weight:147.17PF-07054894
CAS:PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.Formula:C24H30N6O4Color and Shape:SolidMolecular weight:466.53Nipradolol
CAS:Nipradolol blocks alpha-1-adrenergic receptors, lowers IOP in rabbits, and reduces NA-induced muscle contraction and dog artery vasodilation.Formula:C15H22N2O6Color and Shape:SolidMolecular weight:326.35Nenocorilant
CAS:Nenocorilant (Relacorilant) is an orally active glucocorticoid receptor (GR) antagonist (Ki: 0.15 nM). Nenocorilant can be used to study tumours.Formula:C26H21F4N7O3SColor and Shape:SolidMolecular weight:587.55SGK1-IN-3
CAS:SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.Formula:C23H20Cl2N6O3SColor and Shape:SolidMolecular weight:531.414Enpp-1-IN-11
Enpp-1-IN-11 inhibits ENPP1 with a 45 nM Ki, is plasma stable, and has low clearance in human/mouse livers, potentially aiding cancer research.Formula:C15H15N5O3SColor and Shape:SolidMolecular weight:345.38DS69910557
DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.Formula:C32H33Cl2FN4O3Color and Shape:SolidMolecular weight:611.53METTL3-IN-3
CAS:METTL3-IN-3 is a polyheterocyclic compound, acts as METTL3 inhibitor .Formula:C26H28BrFN6O2Color and Shape:SolidMolecular weight:555.44Hcyb1
Hcyb1 specifically inhibits PDE2A with 0.57 μM IC50, over 250x selective, and has neuroprotective and antidepressant effects.Formula:C24H20N4OColor and Shape:SolidMolecular weight:380.44Amdinocillin methylacetate
CAS:Amdinocillin methylacetate is a Synthetic penicillin.Formula:C18H27N3O4SColor and Shape:SolidMolecular weight:381.49Exicorilant
CAS:Exicorilant is a selective oral GR antagonist (Ki: 7 nM) that may reduce obesity, glucose intolerance, & dyslipidemia.Formula:C26H23F4N7O3SPurity:98%Color and Shape:SolidMolecular weight:589.56CPX-351
CAS:CPX-351 (Vyxeos) is a liposomal encapsulant of cytarabine and Zoerythromycin with potential antitumor activity.Formula:C36H42N4O15Purity:98.95% - 99.763%Color and Shape:SolidMolecular weight:770.74SR121566A
CAS:SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Formula:C20H25N5O4SPurity:98%Color and Shape:SolidMolecular weight:431.51Quinagolide Free Base
CAS:Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.Formula:C20H33N3O3SColor and Shape:SolidMolecular weight:395.56J-104132
CAS:J-104132: potent human ETA/B antagonist; Ki: ETA=0.034nM, ETB=0.104nM; prevents ET-1 effects, ED50 i.v.=0.045mg/kg, p.o.=0.35mg/kg.Formula:C31H33NO7Purity:98%Color and Shape:SolidMolecular weight:531.60ICA-105665
CAS:ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.Formula:C19H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:355.34Lepidozin G
Lepidozin G blocks cancer growth (IC50=4.2-5.7μM) and triggers apoptosis in PC-3 cells via mitochondria.Formula:C30H48O4Color and Shape:SolidMolecular weight:472.7ONO-AE1-329
CAS:ONO-AE1-329 is a novel agonist of the prostaglandin PGE2 receptor EP4.Formula:C22H30O6S2Color and Shape:SolidMolecular weight:454.6Anti-inflammatory agent 6
Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.Formula:C22H20O12Color and Shape:SolidMolecular weight:476.39MMG-11 quarterhydrate
MMG-11 quarterhydrate, a potent hTLR2 antagonist, inhibits TLR2/1 and TLR2/6 with IC50s of 1.7μM and 5.7μM; low toxicity.Formula:C15H16O8Color and Shape:SolidMolecular weight:310.78BRD1991
CAS:BRD1991 is a chemical compound that specifically disrupts the interaction between Beclin 1 and Bcl-2, thereby inducing autophagy.Formula:C33H35Cl2N3O4Color and Shape:SolidMolecular weight:608.55(S)-Butaprost free acid
CAS:(S)-Butaprost (free acid) is a potent and highly selective EP2 receptor agonist[1].Formula:C23H38O5Color and Shape:SolidMolecular weight:394.54Nrf2 activator-2
Compound O15, an Osthole derivative, is a potent Nrf2 agonist with an EC50 of 2.9 μM; it inhibits Keap1-Nrf2 binding and Nrf2 ubiquitination.Formula:C20H17BrO3Color and Shape:SolidMolecular weight:385.25CDK8-IN-5
CAS:CDK8-IN-5: potent CDK8 inhibitor, IC50=72 nM, boosts IL-10 by 43%, may aid inflammatory bowel disease research.Formula:C26H22N2O4Color and Shape:SolidMolecular weight:426.46AY-22,252
CAS:AY-22,252 is an inhibitor of beef heart & rat brain nucleoside-3',5'- monophosphate phosphodiesterase.Formula:C27H37NaO7Color and Shape:SolidMolecular weight:496.57ONO-9780307
CAS:ONO-9780307 is a specific antagonist of LPA1 (lysophosphatidic acid receptor 1) (IC50: 2.7 nM).Formula:C30H35NO7Color and Shape:SolidMolecular weight:521.6Purine phosphoribosyltransferase-IN-2
Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17Pparδ agonist 5
Pparδ agonist 5 is a selective, orally active PPARδ agonist with an EC50 of 0.335 μM and better selectivity than GW0742.Formula:C23H21F3N2O2SColor and Shape:SolidMolecular weight:446.49Deltasonamide 2 hydrochloride
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.Formula:C30H40Cl2N6O4S2Purity:98%Color and Shape:SolidMolecular weight:683.71Topo I/COX-2-IN-1
Topo I/COX-2-IN-1: potent dual inhibitor; IC50 0.24μM (COX-2), 4.42μM (Topo I); anti-cancer; induces apoptosis, halts migration.Formula:C21H18ClFN2O3Color and Shape:SolidMolecular weight:400.83TCMDC-125431
TCMDC-125431 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystals.Formula:C25H27N3O2SColor and Shape:SolidMolecular weight:433.57ACT-777991
CAS:ACT-777991: oral CXCR3 blocker, stable in microsomes/hepatocytes, inhibits T-cell migration to CXCL11.Formula:C20H20F6N8O2SColor and Shape:SolidMolecular weight:550.48GT-055
GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.Formula:C13H20F3N5O8SColor and Shape:SolidMolecular weight:463.39JAK2 JH2 binder-1
CAS:JAK2 JH2 binder-1: potent, selective, Ki=37.1 nM, potential for studying myeloproliferative neoplasms.Formula:C29H25N7O6SColor and Shape:SolidMolecular weight:599.62Antitumor agent-50
Antitumor agent-50 (compound 1a) is a thiazolidinone.Formula:C17H14FNO3SColor and Shape:SolidMolecular weight:331.36Sekdel sequence
CAS:Sekdel sequence, as a signal, leads to retention of at least two proteins in the endoplasmic reticulum of animal cells.Formula:C29H49N7O14Color and Shape:SolidMolecular weight:719.74Anti-inflammatory agent 9
Benzimidazothiazole-derived Compound 28 from tilomisole targets COX-2, has potent anti-inflammatory effects & is orally bioavailable.Formula:C18H15N5O2SColor and Shape:SolidMolecular weight:365.41RO5461111
CAS:RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.Formula:C27H24F6N4O4SColor and Shape:SolidMolecular weight:614.56
