Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,901 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,377 products)
- Other Inhibitors(35,852 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,430 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tubulin inhibitor 13
CAS:Tubulin inhibitor 13 (E27), IC50 16.1 μM, blocks tubulin polymerization, cancer cell migration, and invasion, induces apoptosis.Formula:C25H21N3O4Color and Shape:SolidMolecular weight:427.45SP-471
SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.Formula:C33H26BrN5Color and Shape:SolidMolecular weight:572.5BRD7929
CAS:BRD7929 is a multistage antimalarial inhibitor for single-dose treatment of malaria in mouse models.Formula:C33H38N4O2Color and Shape:SolidMolecular weight:522.68Hypoglycemic agent 1
CAS:Hypoglycemic agent 1 has an action for lowering blood sugar. It acts as a therapeutic and/or prophylactic agent for diabetes.Formula:C25H24FN5O4Purity:98%Color and Shape:SolidMolecular weight:477.49Mu opioid receptor antagonist 3
Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.Formula:C25H28N2O4SColor and Shape:SolidMolecular weight:452.57SLC4011540
SLC4011540 is a potent and selective SphK1/2 dual inhibitor with Ki value of 120 nM and 90 nM respectively.Formula:C24H23ClF3N7OSColor and Shape:SolidMolecular weight:550PARP1-IN-5
PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.Formula:C25H24N2O5SColor and Shape:SolidMolecular weight:464.53AMG-548 dihydrochloride
AMG-548 dihydrochloride, an oral p38α inhibitor (Ki: 0.5 nM), selectively targets p38β, γ, δ, inhibits TNFα (IC50: 3 nM), and suppresses Wnt signaling.Formula:C29H29Cl2N5OColor and Shape:SolidMolecular weight:534.48GSK3527497 HCl
CAS:GSK3527497: potent TRPV4 inhibitor, IC50=12 nM, targets heart/respiratory issues, for oral/IV use, low-dose effective.Formula:C17H17Cl2FN4O4SColor and Shape:SolidMolecular weight:463.3054CLR01 sodium
CAS:CLR01 is a tweezer reducing α-synuclein in MSA, inhibits SOD1 in ALS, blocks Ebola/Zika, stabilizes proteins, and lessens mutant p53 toxicity.Formula:C42H30Na2O8P2Color and Shape:SolidMolecular weight:770.6211DS89002333
DS89002333: oral PRKACA inhibitor with 0.3 nM IC50, effective against FL-HCC with DNAJB1-PRKACA fusion in xenografts.Formula:C22H20ClF2N3O3Color and Shape:SolidMolecular weight:447.86Amicoumacin A
CAS:Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.Formula:C20H29N3O7Purity:98%Color and Shape:SolidMolecular weight:423.46DNA gyrase B-IN-1
DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.Formula:C23H18ClF3N6O4SColor and Shape:SolidMolecular weight:566.94Squalamine
CAS:Squalamine is an aminosterol compound, with potent broad spectrum antiviral activity.Formula:C34H65N3O5SPurity:98%Color and Shape:SolidMolecular weight:627.96Lumirubin
CAS:Lumirubin is a water-soluble photoproduct of bilirubin formed in vivo during phototherapy.Formula:C33H36N4O6Color and Shape:SolidMolecular weight:584.66Verrucarin A
CAS:Verrucarin A, a mycotoxin from Myrothecium verrucaria, inhibits protein synthesis, leukemia growth, and triggers apoptosis.Formula:C27H34O9Color and Shape:SolidMolecular weight:502.55GW311616 hydrochloride
CAS:GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).Formula:C19H32ClN3O4SPurity:98%Color and Shape:SolidMolecular weight:433.99hCAIX/XII-IN-5
Coumarin 9a: Selective inhibitor of hCA IX/XII (Ki 93.3/85.7 nM), blocks cancer cell growth, and induces apoptosis.Formula:C18H13NO3Color and Shape:SolidMolecular weight:291.3CN-716 HCl
CAS:cn-716 is a novel Zika virus (ZIKV) NS2B-NS3pro protease inhibitor.Formula:C22H33BCl2N6O4Color and Shape:SolidMolecular weight:527.25Antimalarial agent 9
Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.Formula:C28H32BrN3O2Color and Shape:SolidMolecular weight:522.48NSD2-IN-1
CAS:NSD2-IN-1: potent, selective NSD2-PWWP1 inhibitor, IC50 0.11 μM, induces gene expression changes, apoptosis, cell cycle arrest.Formula:C29H31N5Color and Shape:SolidMolecular weight:449.59Musettamycin
CAS:Musettamycin triggers erythroid differentiation in blood cells, acts like anthracycline antibiotics, but only inhibits gram-positive bacteria.Formula:C36H45NO14Color and Shape:SolidMolecular weight:715.74TRK-IN-12
CAS:TRK-IN-12 (9e), a macrocyclic TRK inhibitor (G595R IC50=13.1 nM), outperforms LOXO-101 in Ba/F3-NTRK1 cells.Formula:C18H19ClFN5O3SColor and Shape:SolidMolecular weight:439.89L 731735
CAS:L 731735 is a farnesyltransferase inhibitor.Formula:C19H40N4O4SPurity:98%Color and Shape:SolidMolecular weight:420.61NS2B/NS3-IN-5
Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.Formula:C14H9IN2O3SColor and Shape:SolidMolecular weight:412.2ORP-101
CAS:ORP-101: large, stable molecule with partial μ agonist, full κ antagonist properties.Formula:C60H84N2O8Color and Shape:SolidMolecular weight:961.32AVE 0991
CAS:AVE 0991 is a nonpeptide analog of angiotensin-(1-7), a Mas agonist with inhibitory effects on [125I]-Ang-(1-7) and on neuroinflammation in Alzheimer's disease.Formula:C29H32N4O5S2Purity:99.73%Color and Shape:SolidMolecular weight:580.72NMDA receptor antagonist-3
NMDA antagonist-3: recovery rate 40% at 100 μM, low toxicity in SH-SY5Y, human stem cells.Formula:C13H19N3O6Color and Shape:SolidMolecular weight:313.31PX-316
CAS:PX-316: AKT inhibitor, reduces Akt activity by 78% in HT-29 xenografts, effective against MCF-7 and HT-29 cancers, well-tolerated intravenously.Formula:C28H57O10PColor and Shape:SolidMolecular weight:584.72VEGFR-2-IN-26
CAS:VEGFR-2-IN-26 inhibits VEGFR-2 (IC50: 15.5 nM), combating various cancers' cell growth.Formula:C24H19F3N6O2Color and Shape:SolidMolecular weight:480.44DDCPPB-Glu
CAS:DDCPPB-Glu is a 6-5 fused ring heterocycle antifolate that shows antitumor activity.Formula:C22H27N5O5Purity:98%Color and Shape:SolidMolecular weight:441.48C.I. Pigment Red 60
CAS:C.I. Pigment Red 60 is a bright, scarlet, semi-transparent red pigment.Formula:C17H9N2Na3O9S2Purity:98%Color and Shape:SolidMolecular weight:518.35SSTR5 antagonist 2 hydrochloride
SSTR5 antagonist 2 hydrochloride: potent, oral SSTR5 blocker with potential in type 2 diabetes research.Formula:C32H36ClFN2O5Color and Shape:SolidMolecular weight:583.09P2X7 receptor antagonist-1
P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.Formula:C22H20F4N2O3Color and Shape:SolidMolecular weight:436.4IDO2-IN-1
CAS:IDO2-IN-1: potent oral IDO2 inhibitor, IC50 = 112 nM, for inflammatory autoimmunity research.Formula:C21H21BrN10O3Color and Shape:SolidMolecular weight:541.36LSD1/ER-IN-1
LSD1/ER-IN-1 inhibits ER & LSD1 (IC50: 1.55 μM), and fights MCF-7 breast cancer (IC50: 8.79 μM).Formula:C23H18FNO6SColor and Shape:SolidMolecular weight:455.46EGFR-IN-38
CAS:EGFR-IN-38: low-toxic acrylamide-derived EGFR inhibitor, targets NSCLC, patented for research on EGFR mutation-related diseases.Formula:C25H24ClN7O2Color and Shape:SolidMolecular weight:489.96GNTI dihydrochloride
CAS:κ opioid receptor antagonistFormula:C27H30ClN5O3Purity:98%Color and Shape:SolidMolecular weight:508.01Glutaminyl cyclases-IN-1
Glutaminyl cyclase inhibitor IsoQC-IN-1: IC50=12 nM for QC, 73 nM for isoQC; blocks CD47/SIRPα; boosts THP-1, U937 macrophage phagocytosis.Formula:C25H30N6O2SColor and Shape:SolidMolecular weight:478.61RWJ-56110
CAS:protease-activated receptor-1 (PAR1) antagonistFormula:C41H43Cl2F2N7O3Purity:98%Color and Shape:SolidMolecular weight:790.73Desacetylravidomycin
CAS:Desacetylravidomycin is a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp. WK-6326.Formula:C29H31NO8Color and Shape:SolidMolecular weight:521.56BRD4-BD1/2-IN-2
CAS:BRD4-BD1/2-IN-2 inhibits BRD4 BD1/BD2 with IC50 <300 nM/<0.5 nM (WO2021233371A1).Formula:C30H33N5O4Color and Shape:SolidMolecular weight:527.61Udifitimod
CAS:Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.Formula:C25H33NO2Color and Shape:SolidMolecular weight:379.54DC41
CAS:DC41 is a CC-1065-based cancer drug, an antibody-linked DNA alkylator.Formula:C37H34ClN5O4SPurity:98%Color and Shape:SolidMolecular weight:680.22Saphenamycin
CAS:Saphenamycin is an antibiotic from a strain of Streptomyces.Formula:C23H18N2O5Purity:98%Color and Shape:SolidMolecular weight:402.40ACSS2-IN-1
CAS:ACSS2-IN-1, a potent ACSS2 inhibitor, has IC50 0.01-<1 nM; useful in cancer research.Formula:C27H25ClN6O2Color and Shape:SolidMolecular weight:500.98MRL-494
MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.
Formula:C26H35FN16O2Purity:98%Color and Shape:SolidMolecular weight:622.66ACHN-975
CAS:ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formula:C20H23N3O4Purity:98%Color and Shape:SolidMolecular weight:369.41U92016A hydrochloride
CAS:U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.Formula:C19H26ClN3Color and Shape:SolidMolecular weight:331.89TT15
CAS:TT15 is an agonist of the GLP-1R.Formula:C51H44Cl2N4O6Color and Shape:SolidMolecular weight:879.82
