Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,852 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,430 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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PHGDH-IN-2
PHGDH-IN-2: potent PHGDH inhibitor, IC50=5.2μM; hinders PHGDH cancer cell growth & serine synthesis in MDA-MB-468.Formula:C22H20N4O3SColor and Shape:SolidMolecular weight:420.48KMH-233
CAS:KMH-233 effectively blocks LAT1, inhibiting L-leucine uptake and cell growth, boosting betastatin and cisplatin efficacy at 25 μM.Formula:C32H25N7O5Color and Shape:SolidMolecular weight:587.58Antitubercular agent-29
Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.Formula:C20H12ClN3O5Color and Shape:SolidMolecular weight:409.78VHL Ligand 8
CAS:VHL Ligand 8, a VHL ligand essential for synthesizing ARD-266, acts as a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader.Formula:C23H29N3O6Purity:98%Color and Shape:SolidMolecular weight:443.49M1069
M1069 is an oral A2A/A2B receptor antagonist, 100x more selective over A1/A3, with antitumor properties by blocking adenosine's immunosuppressive effects.Formula:C25H30N4O8SColor and Shape:SolidMolecular weight:546.59LXRβ agonist-2
CAS:LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM.Formula:C32H31F6N3O7Purity:98%Color and Shape:SolidMolecular weight:683.59Antitumor agent-58
Antitumor agent-58 suppresses tumor growth, colony formation, cell migration, and induces mitochondrial dysfunction in MGC-803 cells.Formula:C27H28F3N9SColor and Shape:SolidMolecular weight:567.63SARS-CoV-2-IN-24
SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.Formula:C27H30N4O5Color and Shape:SolidMolecular weight:490.55L-I-OddU
CAS:L-I-OddU: Selective anti-EBV, halts virus DNA/protein synthesis. EC50: 0.03 µM, low toxicity (CC50: 1000 nM).Formula:C8H9IN2O5Color and Shape:SolidMolecular weight:340.07MCTR2
CAS:MCTR2, synthesized from DHA in macrophages, aids in tissue repair and reduces inflammation by promoting eicosanoid PGD2 and PGF2α decrease.Formula:C27H40N2O6SColor and Shape:SolidMolecular weight:520.68Sdz 210-096
CAS:Sdz 210-096: a 14 beta-benzyl morphinan, mu/kappa opiate receptor antagonist, stimulates LH secretion in rats.Formula:C27H31NO2Color and Shape:SolidMolecular weight:401.54Isoleucyl tRNA synthetase-IN-1
CAS:Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS).Formula:C23H35N5O7SColor and Shape:SolidMolecular weight:525.62Calphostin I
CAS:Calphostins, from Cladosporium fungus, inhibit PKC. Notably, calphostin C is a potent biochemical tool.Formula:C44H38O15Color and Shape:SolidMolecular weight:806.76LP-284
CAS:LP-284 is a DNA alkylating agent effective against solid tumors and hematologic cancers like MCL.Formula:C16H20N2O4Color and Shape:SolidMolecular weight:304.34RWJ-56110
CAS:protease-activated receptor-1 (PAR1) antagonistFormula:C41H43Cl2F2N7O3Purity:98%Color and Shape:SolidMolecular weight:790.734'-Ethynyl-2'-deoxyadenosine
CAS:4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).Formula:C12H13N5O3Purity:98%Color and Shape:SolidMolecular weight:275.2614α-Demethylase/DNA Gyrase-IN-1
14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.Formula:C26H22N4O4Color and Shape:SolidMolecular weight:454.48Antitumor agent-78
Antitumor agent-78 blocks GPx-4, raises COX2, triggers apoptosis, halts EMT, and stifles cancer cell growth and migration.Color and Shape:SoildYW3-56
CAS:YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.Formula:C27H32ClN5O2Color and Shape:SolidMolecular weight:494.03FPI-1465
CAS:FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.Formula:C11H18N4O7SColor and Shape:SolidMolecular weight:350.35YK5
CAS:YK5 is an allosteric inhibitor pocket of Hsp70 and represents a previously unknown chemical tool to investigate cellular mechanisms associated with Hsp70.Formula:C18H24N8O3SPurity:98%Color and Shape:SolidMolecular weight:432.50BM635 hydrochloride
BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.Formula:C25H30ClFN2OColor and Shape:SolidMolecular weight:428.97Adafosbuvir
CAS:Adafosbuvir has antiviral activity.Formula:C22H29FN3O10PColor and Shape:SolidMolecular weight:545.457Methyl 5-thia-6,8,11,14-eicosatetraenoate
CAS:Methyl 5-thia-6,8,11,14-eicosatetraenoate is a bioactive chemical.Formula:C20H32O2SColor and Shape:SolidMolecular weight:336.53Carbonic anhydrase inhibitor 10
CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.Formula:C14H17N5O3SColor and Shape:SolidMolecular weight:335.38FGFR4-IN-10
FGFR4-IN-10 (compound 5a) is a potent, selective FGFR4 inhibitor with IC50 of 70.7 nM, sparing FGFR1-3.Formula:C20H19F3N6O3Color and Shape:SolidMolecular weight:448.4Novokinin
CAS:Angiotensin AT2 receptor agonistFormula:C39H61N11O7Purity:98%Color and Shape:SolidMolecular weight:795.97Lapaquistat
CAS:Lapaquistat: active TAK-475 metabolite; reduces cholesterol synthesis and statin myotoxicity.Formula:C31H39ClN2O8Purity:98%Color and Shape:SolidMolecular weight:603.1Colistin adjuvant-2
Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].Formula:C14H7Cl2F3N2OColor and Shape:SolidMolecular weight:347.12Sulprostone
CAS:EP3 and EP1 receptor agonistFormula:C23H31NO7SPurity:98%Color and Shape:White To Off-White SolidMolecular weight:465.56Antibiotic MA 144M1
CAS:Antibiotic MA 144M1, an anthracycline, targets gram-positive bacteria and animal tumors; derived from Streptomyces fermentation or aclacinomycin A conversion.Formula:C42H55NO15Color and Shape:SolidMolecular weight:813.88Bomedemstat hydrochloride
Bomedemstat (IMG-7289) hydrochloride, an oral LSD1 inhibitor, has anticancer properties, blocking cell growth and triggering apoptosis.Formula:C28H35ClFN7O2Color and Shape:SolidMolecular weight:556.08Spicamycin
CAS:Spicamycin can be used as a potent inducer of differentiation of human myeloid leukemia cells (HL-60) and murine myeloid leukemia cells (M1).Formula:C30H51N7O7Color and Shape:SolidMolecular weight:621.77FGI-106
CAS:FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.Formula:C28H38N6Purity:98%Color and Shape:SolidMolecular weight:458.64Deldeprevir Na
CAS:Deldeprevir Na is an Antiviral Polyprotein cleavage inhibitor. HCV NS3/4A inhibitor.Formula:C45H55F2N6NaO8S2Color and Shape:SolidMolecular weight:933.08VU0463271 quarterhydrate
VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].Formula:C19H20N4O2S2Color and Shape:SolidMolecular weight:387Lasonolide A
CAS:Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.Formula:C41H60O9Color and Shape:SolidMolecular weight:696.91GSD-11
GSD-11: Potent, selective anti-austerity agent; blocks Akt/mTOR pathway, hinders PANC-1 cell migration & colony growth. Promising for pancreatic cancer study.Formula:C20H28O2Color and Shape:SolidMolecular weight:300.44Keap1-Nrf2-IN-4
Keap1-Nrf2-IN-4 hinders MGC-803 cell growth (IC50=2.55μM), migration, and induces apoptosis with low toxicity.Formula:C26H34N2OColor and Shape:SolidMolecular weight:390.56HIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.Formula:C16H15F2N3OSColor and Shape:SolidMolecular weight:335.37PTP1B-IN-3 diammonium
PTP1B-IN-3 diammonium, an oral enzyme inhibitor, has potent antidiabetic and anticancer effects, with a 120 nM IC50.Formula:C12H13BrF2N3O3PColor and Shape:SolidMolecular weight:396.12HBV-IN-20
HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).Color and Shape:SolidBMS-986118
CAS:BMS-986118 is a GPR40 full agonist targeting type II diabetes, prompting insulin release without hypoglycemia risk.Formula:C25H28ClF3N4O4Purity:98%Color and Shape:SolidMolecular weight:540.96Tuberculosis inhibitor 4
TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.Formula:C23H26N2O3SColor and Shape:SolidMolecular weight:410.53AM-9514
CAS:AM-9514: a potent Glucokinase activator with strong in vitro results, good pharmacokinetics, and efficacy in diabetes.Formula:C18H25N5O4Color and Shape:SolidMolecular weight:375.42DNA crosslinker 3 dihydrochloride
CAS:Compound 1: a DNA minor groove binder with 1.4°C ΔTm; useful in cancer research.Formula:C15H22Cl2N8OColor and Shape:SolidMolecular weight:401.29NDM-1 inhibitor-3
NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.Formula:C16H12O4Purity:99.67%Color and Shape:SolidMolecular weight:268.26L 731735
CAS:L 731735 is a farnesyltransferase inhibitor.Formula:C19H40N4O4SPurity:98%Color and Shape:SolidMolecular weight:420.61BRD1991
CAS:BRD1991 is a chemical compound that specifically disrupts the interaction between Beclin 1 and Bcl-2, thereby inducing autophagy.Formula:C33H35Cl2N3O4Color and Shape:SolidMolecular weight:608.55Tamitinol
CAS:Tamitinol is a neurotropic drug. It has been found to help symptoms of obsessive rumination in conjunction with maprotiline.Formula:C12H20N2OSPurity:98%Color and Shape:SolidMolecular weight:240.37
