Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,785 products)
- Apoptosis(6,253 products)
- Cell Cycle/Checkpoint(4,833 products)
- Chromatin/Epigenetics(2,588 products)
- Cytoskeletal Signaling(1,532 products)
- DNA Damage/DNA Repair(2,883 products)
- Endocrinology/Hormones(3,747 products)
- Enzyme(3,670 products)
- GPCR/G-Protein(8,977 products)
- Immunology and Inflammation(3,777 products)
- Influenza Virus(299 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,248 products)
- Membrane Transporter/Ion Channel(3,147 products)
- Metabolism(10,143 products)
- Microbiology/Virology(7,585 products)
- Neuroscience(10,341 products)
- Other Inhibitors(35,820 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,413 products)
- Proteases/Proteasome(1,680 products)
- Stem Cell and Derivatives(747 products)
- Tyrosine Kinase/Adaptors(1,948 products)
- Ubiquitination(1,719 products)
Show 16 more subcategories
Found 66565 products of "Inhibitors"
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Antitubercular agent-15
Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.Formula:C21H29FN2Color and Shape:SolidMolecular weight:328.47ALK-IN-23
ALK-IN-23 inhibits ALK (IC50: 1.6-0.71 nM), hinders cancer cell spread, forms colonies in vitro, and reduces tumors in mice with low toxicity.Formula:C26H29ClN8O3SColor and Shape:SolidMolecular weight:569.08MCTR1
CAS:MCTR1, a pro-resolving mediator derived from DHA, promotes tissue repair and reduces inflammation by enhancing phagocytosis and decreasing eicosanoids.Formula:C32H47N3O9SColor and Shape:SolidMolecular weight:649.8HDAC6/HSP90-IN-2
HDAC6/HSP90-IN-2, a cancer research chemical, inhibits HDAC6 & Hsp90 with IC50s of 105.7 & 61 nM.Formula:C19H22N2O5Color and Shape:SolidMolecular weight:358.39Cacospongionolide B
CAS:Cacospongionolide B from Fasciospongia cavernosa inhibits secretory phospholipase A2, curbing inflammation.Formula:C25H36O4Color and Shape:SolidMolecular weight:400.55CHF-6366
CAS:CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.Formula:C42H48N6O8Color and Shape:SolidMolecular weight:764.87Saprisartan potassium
CAS:Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.Formula:C25H21BrF3KN4O4SColor and Shape:SolidMolecular weight:649.52Beloxepin
CAS:Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.Formula:C19H21NO2Purity:98%Color and Shape:SolidMolecular weight:295.38CV 5975
CAS:CV 5975 is a nonsulfhydryl ACE inhibitor that was investigated for use in hypertension and heart failure.Formula:C22H31N3O5SColor and Shape:SolidMolecular weight:449.56BMS-554417
CAS:BMS-554417 inhibits IGF-IR/insulin receptors, curbing cell proliferation and tumor growth, with IC50 values of 120 nm–>8.5 μmol/L.Formula:C28H30ClN7O2Color and Shape:SolidMolecular weight:532.04Nedocromil sodium
CAS:Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.Formula:C19H17NNaO7Purity:98%Color and Shape:SolidMolecular weight:394.335α-Glucosidase-IN-17
CAS:α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitoryFormula:C30H27NO2SColor and Shape:SolidMolecular weight:465.61OP-2507
CAS:OP-2507, a prostacyclin agonist, is used potentially for the treatment of hepatic insufficiency and hypertension.Formula:C25H41NO4Purity:98%Color and Shape:SolidMolecular weight:419.616,16-Dimethyl prostaglandin E2
CAS:16,16-Dimethyl prostaglandin E2 regulates hematopoietic stem cells via EP2/EP4 and Wnt, taken orally.Formula:C22H36O5Purity:98%Color and Shape:SolidMolecular weight:380.52Pibrozelesin
CAS:Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.Formula:C32H36BrN5O8Color and Shape:SolidMolecular weight:698.56TBK1/IKKε-IN-1
CAS:TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).Formula:C28H26N4O5Purity:98%Color and Shape:SolidMolecular weight:498.53Ganoderic acid R
CAS:Ganoderic acid R: potent anticancer, induces apoptosis, cytotoxic to MDR and sensitive tumor cells.Formula:C34H50O6Color and Shape:SolidMolecular weight:554.76Etamicastat
CAS:Etamicastat can be used in the research of cardiovascular diseases.Formula:C14H15F2N3OSPurity:98%Color and Shape:SolidMolecular weight:311.35AMXI-5001 hydrochloride
AMXI-5001 hydrochloride, an oral inhibitor of PARP1/2 and microtubules, shows greater potency and selective anti-cancer effects.Formula:C25H21ClFN5O3Color and Shape:SolidMolecular weight:493.92BRD7539
CAS:BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.Formula:C23H22FN3O2Purity:98%Color and Shape:SolidMolecular weight:391.44Diospyrin
CAS:Diospyrin is a plant product that has significant inhibitory effect on the growth of Leishmania donovani promastigotes.Formula:C22H14O6Color and Shape:SolidMolecular weight:374.34STAT3-IN-9
STAT3-IN-9 hinders STAT3 at Tyr705, doesn't affect STAT1 Tyr701, induces apoptosis, and arrests cells in G2/M phase.Formula:C22H21N3O4Color and Shape:SolidMolecular weight:391.42CXCR7 modulator 2
CAS:CXCR7 modulator 2 is a 7-type C-X-C chemokine receptor (CXCR7) modulator with a Ki of 13 nM.Formula:C29H42N6O3Color and Shape:SolidMolecular weight:522.68EICAR
CAS:EICAR: IMP dehydrogenase inhibitor with anticancer and antiviral properties, failed in leukemia trials, active against various viruses but not SARS.Formula:C11H13N3O5Color and Shape:SolidMolecular weight:267.24FAAH/MAGL-IN-3
FAAH/MAGL-IN-3 irreversibly inhibits FAAH (IC50: 179 nM) & MAGL (IC50: 759 nM) with low PAMPA permeability.Formula:C21H25N3O6SColor and Shape:SolidMolecular weight:447.5PTP1B-IN-16
PTP1B-IN-16: selective benzimidazole inhibitor of PTP1B, Ki: 12.6 μM, potential for type 2 diabetes research.Formula:C26H18ClN3O4SColor and Shape:SolidMolecular weight:503.96FGI-106
CAS:FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.Formula:C28H38N6Purity:98%Color and Shape:SolidMolecular weight:458.64Tubulin polymerization-IN-32
Tubulin polymerization-IN-32: a cancer cell growth inhibitor used for research in cancers like lymphoma.Formula:C29H30N2O7Color and Shape:SolidMolecular weight:518.56Tamitinol
CAS:Tamitinol is a neurotropic drug. It has been found to help symptoms of obsessive rumination in conjunction with maprotiline.Formula:C12H20N2OSPurity:98%Color and Shape:SolidMolecular weight:240.37Ro 0437626
CAS:P2X1 purinergic receptor antagonistFormula:C27H35N5O4SPurity:98%Color and Shape:SolidMolecular weight:525.66JAK2 JH2 binder-1
CAS:JAK2 JH2 binder-1: potent, selective, Ki=37.1 nM, potential for studying myeloproliferative neoplasms.Formula:C29H25N7O6SColor and Shape:SolidMolecular weight:599.62PptT-IN-1
PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.Formula:C18H29N5O2Color and Shape:SolidMolecular weight:347.46LasR-IN-1
LasR-IN-1 (9g) strongly inhibits LasR, potent vs E. coli, with a 28.13 μM MIC against P. aeruginosa.Formula:C23H21N3O2Color and Shape:SolidMolecular weight:371.43FAK-IN-3
FAK-IN-3 inhibits FAK, reduces PA-1 cell migration/invasion, and tumor growth, with no major side effects.
Formula:C28H28N6O4Color and Shape:SolidMolecular weight:512.56MK-2748
CAS:MK-2748 is an inhibitor of NS3 protease, hepatitis C virus.Formula:C42H56N6O10SColor and Shape:SolidMolecular weight:836.99YW3-56
CAS:YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.Formula:C27H32ClN5O2Color and Shape:SolidMolecular weight:494.03M-89 MLL inhibitor
CAS:M-89, a potent Menin-MLL blocker: Kd 1.4 nM, IC50 25 nM for MV4;11 cells, 55 nM for MOLM-13, >100x selective over HL-60.Formula:C37H47N5O4SColor and Shape:SolidMolecular weight:657.87LT-850-166
LT-850-166 is a potent inhibitor of FLT3 and has shown efficacy in overcoming a wide range of FLT3 mutations.Formula:C30H29Cl2N7OColor and Shape:SolidMolecular weight:574.5KH-259
KH-259: potent, selective CNS-penetrant HDAC6 inhibitor with 0.26 μM IC50; shows antidepressant effects in mice.Formula:C20H25N3O2Color and Shape:SolidMolecular weight:339.43Vibegron
CAS:Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).Formula:C26H28N4O3Color and Shape:SolidMolecular weight:444.53Antimalarial agent 3
Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.Formula:C15H16BrN3O2Color and Shape:SolidMolecular weight:350.21Amrubicin HCl
CAS:Amrubicin (SM-5887), an anthracycline, treats lung cancer by inhibiting DNA replication and topoisomerase II, with less cardiac toxicity.Formula:C25H25NO9Color and Shape:SolidMolecular weight:483.47EGFR/HER2-IN-7
EGFR/HER2-IN-7: Potent, selective dual inhibitor for MCF-7 cancer; IC50: EGFR 0.18μM, HER2 0.146μM, DHFR 0.907μM.Formula:C19H21N3O2SColor and Shape:SolidMolecular weight:355.45WW437
WW437 is a histone deacetylase (HDAC) inhibitor that exhibits potent anti-breast cancer activity both in vitro and in vivo.Formula:C23H27N5O4Color and Shape:SolidMolecular weight:437.49PARP-1/HDAC-IN-1
CAS:PARP-1/HDAC-IN-1 is a PARP-1 and HDAC6 inhibitor with anticancer, antimigratory, and antiangiogenic activities and is used in tumor research.Formula:C22H18N4O4Purity:95.94%Color and Shape:SolidMolecular weight:402.4Tezampanel hydrate
CAS:Tezampanel is used for the treatment of migraine, neuropathic pain.Formula:C13H23N5O3Color and Shape:SolidMolecular weight:297.35LJ-4517
LJ-4517 is an effective A2AAR antagonist (Ki=18.3 nM). LJ-4517 can effectively replace the binding of [3H] ZM241385 at WT A2AAR.Formula:C19H21N5O3SColor and Shape:SolidMolecular weight:399.47CDK9-IN-13
CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.Formula:C27H35N5O2Color and Shape:SolidMolecular weight:461.6E-3030 free acid
CAS:E-3030 free acid, a PPAR agonist, lowers blood glucose, triglycerides, and insulin; boosts adiponectin; reduces apo C-III; and raises lipoprotein lipase.Formula:C22H23ClFNO5Purity:98%Color and Shape:SolidMolecular weight:435.87Chitin synthase inhibitor 11
Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.Formula:C24H24N4O8Color and Shape:SolidMolecular weight:496.47
