Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,760 products)
- Apoptosis(6,191 products)
- Cell Cycle/Checkpoint(4,809 products)
- Chromatin/Epigenetics(2,579 products)
- Cytoskeletal Signaling(1,502 products)
- DNA Damage/DNA Repair(2,887 products)
- Endocrinology/Hormones(3,703 products)
- Enzyme(3,671 products)
- GPCR/G-Protein(8,967 products)
- Immunology and Inflammation(3,704 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(414 products)
- MAPK Signaling(1,248 products)
- Membrane Transporter/Ion Channel(3,137 products)
- Metabolism(10,092 products)
- Microbiology/Virology(7,553 products)
- Neuroscience(10,304 products)
- Other Inhibitors(35,763 products)
- Oxidation-Reduction(39 products)
- PI3K/Akt/mTOR Signaling(1,402 products)
- Proteases/Proteasome(1,671 products)
- Stem Cell and Derivatives(740 products)
- Tyrosine Kinase/Adaptors(1,923 products)
- Ubiquitination(1,717 products)
Show 16 more subcategories
Found 66570 products of "Inhibitors"
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Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Formula:C17H10ClFN2Color and Shape:SolidMolecular weight:296.73HBV-IN-24
HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.Formula:C23H27NO6Color and Shape:SolidMolecular weight:413.46Anticancer agent 143
CAS:Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM.Formula:C19H15BrF2N3O6PS2Purity:98%Color and Shape:SolidMolecular weight:594.34iNOS/PGE2-IN-1
iNOS/PGE2-IN-1: iNOS/PGE2 inhibitor, reduces LPS-induced NO, low ulcer risk, anti-inflammatory.Formula:C26H22ClN3O4Color and Shape:SolidMolecular weight:475.9212(S)-HETE
CAS:Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.
Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47Chitin synthase inhibitor 7
Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.Formula:C24H25N3O5Color and Shape:SolidMolecular weight:435.47SM-433 hydrochloride
SM-433 hydrochloride, a Smac mimetic & IAP inhibitor, binds XIAP BIR3; potent IC50 <1 μM. (Patent WO2008128171A2)Formula:C32H44ClN5O4Color and Shape:SolidMolecular weight:598.18Tonantzitlolone
CAS:Tonantzitlolone activates TRPC1/4/5 channels, PKCα/θ, inhibits IRS1/PI3K/AKT, and triggers HSF1 to induce glucose dependence.Formula:C26H40O7Color and Shape:SolidMolecular weight:464.59Human carbonic anhydrase II-IN-2
Compound R-13, a potent inhibitor of hCA I/II/IV/IX with K i s of 60.7, 320.7, 2298, and 35.2 nM.Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5Fonadelpar
CAS:Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.Formula:C25H23F3N2O4SPurity:98%Color and Shape:SolidMolecular weight:504.52NNC 55-0396
CAS:NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.Formula:C30H40Cl2FN3O2Purity:99.00%Color and Shape:SolidMolecular weight:564.56Ref: TM-T12238
1mg66.00€5mg126.00€10mg202.00€25mg354.00€50mg550.00€100mg787.00€1mL*10mM (DMSO)160.00€ATR-IN-19
CAS:ATR-IN-19 (Compound 15 R-configure) is an ATR inhibitor [1].Formula:C18H19N7OSColor and Shape:SolidMolecular weight:381.45Bcl-2-IN-7
Bcl-2-IN-7 inhibits Bcl-2, encourages apoptosis in cancer cells, and has anti-tumor activity with various IC50 values.Formula:C24H22N4O5S2Color and Shape:SolidMolecular weight:510.59DHU-Se1
DHU-Se1: potent anti-inflammatory, releases reactive selenium from macrophages, inhibits iNOS/TNF-α, blocks M0 to M1 polarization.Formula:C23H23N3OSSeColor and Shape:SolidMolecular weight:468.47NUCC-555
CAS:NUCC-555 is a first-in-class antagonist of activin. It opens a completely new approach to inhibiting the activity of TGF-beta receptor superfamily members.Formula:C25H25N5O3Purity:98%Color and Shape:SolidMolecular weight:443.5Amicoumacin A
CAS:Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.Formula:C20H29N3O7Purity:98%Color and Shape:SolidMolecular weight:423.46STA 2
CAS:STA 2 is an analogue of TXA2, a thromboxane receptor in the colonic epithelium.Formula:C21H34O3SColor and Shape:SolidMolecular weight:366.56LAF-153
CAS:LAF-153 is a reversible Methionine Aminopeptidase‑2 (MetAP-2) Inhibitor.Formula:C18H32N2O7Color and Shape:SolidMolecular weight:388.46SHR2415
SHR2415: Potent, selective ERK1/2 inhibitor, oral; ERK1 IC50: 2.8 nM, ERK2 IC50: 5.9 nM; effective in Colo205 (IC50: 44.6 nM), for cancer research.Formula:C23H22ClN7O2Color and Shape:SolidMolecular weight:463.92AVE 0991
CAS:AVE 0991 is a nonpeptide analog of angiotensin-(1-7), a Mas agonist with inhibitory effects on [125I]-Ang-(1-7) and on neuroinflammation in Alzheimer's disease.Formula:C29H32N4O5S2Purity:99.73%Color and Shape:SolidMolecular weight:580.72LY-2979165
CAS:LY-2979165 is a metabotropic glutamate receptor agonist prodrug.Formula:C13H17N5O5SColor and Shape:SolidMolecular weight:355.37HDAC8-IN-2
HDAC8-IN-2 (5o) inhibits both smHDAC8 and hHDAC8 with IC50s of 0.27 μM, 0.32 μM, kills schistosome larvae, and lowers egg laying.Formula:C21H16N2O5Color and Shape:SolidMolecular weight:376.36T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Formula:C36H39FN4OSColor and Shape:SolidMolecular weight:594.78TD-0212 TFA
CAS:TD-0212 TFA is an oral AT1 receptor antagonist & NEP inhibitor with pKi 8.9 & pIC50 9.2.Formula:C30H35F4N3O6SPurity:98%Color and Shape:SolidMolecular weight:641.67MtDTBS-IN-1
MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.Formula:C16H16N4O5Color and Shape:SolidMolecular weight:344.32AChE-IN-5
AChE-IN-5: oral, crosses blood-brain barrier, targets AChE/5-HT1A/SERT, potent with 2.29 nM IC50.Formula:C38H45N5OColor and Shape:SolidMolecular weight:587.8Freselestat
CAS:Freselestat (ONO-6818) inhibits neutrophil elastase, reduces interleukin 8, C5B-9, and inflammation in cardiopulmonary bypass.Formula:C23H28N6O4Color and Shape:SolidMolecular weight:452.51Tubulin inhibitor 16
Tubulin inhibitor 16 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 16 exhibits cytotoxicity in HepG2 cells [1].Formula:C16H12FNO2Color and Shape:SolidMolecular weight:269.27PD 135158
CAS:PD 135158 is a CCK2 receptor antagonist.Formula:C42H61N5O11Purity:98%Color and Shape:SolidMolecular weight:811.96Gamendazole
CAS:Gamendazole is a novel drug candidate for male contraception. It has been shown to reduce fertility in male rats without affecting testosterone levels.Formula:C18H11Cl2F3N2O2Purity:98%Color and Shape:SolidMolecular weight:415.19JAK2/FLT3-IN-1 TFA
JAK2/FLT3-IN-1 (TFA), an oral JAK2/FLT3 inhibitor, shows anticancer properties; IC50: JAK2 (0.7 nM), FLT3 (4 nM), JAK1 (26 nM), JAK3 (39 nM).Formula:C27H35F4N7O3Color and Shape:SolidMolecular weight:581.61GSK3527497
CAS:GSK3527497 is a novel potent and selective inhibitor of transient receptor potential vanilloid-4 (TRPV4).Formula:C17H16ClFN4O4SColor and Shape:SolidMolecular weight:426.85Anti-Influenza agent 3
Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).Formula:C16H22ClNOSColor and Shape:SolidMolecular weight:311.87(±)-J 113397
CAS:(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).Formula:C24H37N3O2Color and Shape:SolidMolecular weight:399.57Lentiginosine
CAS:Lentiginosine is a selective amyloglucosidase inhibitor.Formula:C8H15NO2Color and Shape:SolidMolecular weight:157.21TTA-P1
CAS:TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Formula:C19H27Cl2FN2OColor and Shape:SolidMolecular weight:389.33Triphen diol
CAS:Triphen diol, a phenol diol, fights pancreatic cancer & cholangiocarcinoma, inducing apoptosis via caspase-dependent & -independent paths.Formula:C22H20O4Color and Shape:SolidMolecular weight:348.399(R)-HETE
CAS:9(R)-HETE, 50% of racemic mix, activates RXRγ 1.5x at 300 nM; identified by HPLC comparison.Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47Emtricitabine triphosphate
CAS:Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formula:C8H13FN3O12P3SColor and Shape:SolidMolecular weight:487.19ATP synthase inhibitor 2
CAS:ATP synthase inhibitor 2 blocks P. aeruginosa ATP synthase; IC50=10 μg/mL, fully inhibits at 128 μg/mL.Formula:C21H22N2O3SColor and Shape:SolidMolecular weight:382.48DNA Gyrase-IN-1
DNA Gyrase-IN-1: potent, selective promoter inhibitor. IC50: 2.6 μM, inhibits Mtb, MIC: 0.49 μM. Useful for tuberculosis research.Formula:C24H24FN7O6Color and Shape:SolidMolecular weight:525.49Antitumor agent-47
Antitumor agent-47, a silibinin derivative, shows cytotoxicity in NCI-H1299 (IC50: 8.07µM) and HT29 (IC50: 6.27µM) cells.Formula:C30H27NO11Color and Shape:SolidMolecular weight:577.54Danshenxinkun D
CAS:Danshenxinkun D has antituberculosis H_(37)Rv activity in vitro.Formula:C21H20O4Purity:98%Color and Shape:SolidMolecular weight:336.38Menin-MLL inhibitor 4
CAS:Menin-MLL inhibitor 4 has antitumor activity.Menin-MLL inhibitor 4 is an inhibitor of Menin- MLL (mixed-lineage leukemia protein) interaction .Formula:C32H38FN7O3Purity:98%Color and Shape:SolidMolecular weight:587.69EGFR-IN-48
EGFR-IN-48: potent EGFR inhibitor, oral, IC50: 0.193-66.7 nM, blocks EGFR mutants & BaF3/PC-9 cell proliferation.Color and Shape:SolidHIV-1 inhibitor-44
HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).Formula:C23H26N2O4SColor and Shape:SolidMolecular weight:426.53PNU-248686A
CAS:PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).Formula:C22H18ClNaO5S2Purity:98%Color and Shape:SolidMolecular weight:484.95Anti-inflammatory agent 16
Compound 14 is a peptidomimetic that significantly lowers TNFα, NO, CD40, and CD86, showcasing strong anti-inflammatory effects.Formula:C21H23N5O3Color and Shape:SolidMolecular weight:393.44NLRP3-IN-6
NLRP3-IN-6 (Compound 34) is a selective inhibitor of the NLRP3 inflammasome.Formula:C18H15ClN2O4S3Color and Shape:SolidMolecular weight:454.97KP 10614
CAS:KP 10614 is a new prostacyclin analog that inhibits platelet-polymorphonuclear leukocyte interaction.Formula:C23H32O4Color and Shape:SolidMolecular weight:372.50
