Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,754 products)
- Apoptosis(6,186 products)
- Cell Cycle/Checkpoint(4,807 products)
- Chromatin/Epigenetics(2,573 products)
- Cytoskeletal Signaling(1,503 products)
- DNA Damage/DNA Repair(2,893 products)
- Endocrinology/Hormones(3,702 products)
- Enzyme(3,671 products)
- GPCR/G-Protein(8,963 products)
- Immunology and Inflammation(3,697 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(414 products)
- MAPK Signaling(1,246 products)
- Membrane Transporter/Ion Channel(3,137 products)
- Metabolism(10,096 products)
- Microbiology/Virology(7,552 products)
- Neuroscience(10,302 products)
- Other Inhibitors(35,769 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,402 products)
- Proteases/Proteasome(1,670 products)
- Stem Cell and Derivatives(742 products)
- Tyrosine Kinase/Adaptors(1,921 products)
- Ubiquitination(1,716 products)
Show 16 more subcategories
Found 66573 products of "Inhibitors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
HP590
CAS:HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.Formula:C29H24F6N4O3Color and Shape:SolidMolecular weight:590.52XY153
XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.Formula:C33H34FN3O4Color and Shape:SolidMolecular weight:555.64CBP/p300-IN-18
CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).Formula:C25H27FN4O3Color and Shape:SolidMolecular weight:450.51E6201
CAS:E6201, a dual kinase inhibitor, blocks MEK1/FLT3 and has anti-tumor/psoriasis effects with low IC50s: ERK2 (5.2 nM), JNK (91 nM), p38 MAPK (19 nM).Formula:C21H27NO6Color and Shape:SolidMolecular weight:389.44L 365209
CAS:L 365209 is an oxytocin antagonist.Formula:C40H50N8O6Purity:98%Color and Shape:SolidMolecular weight:738.88Mifepristone methochloride
CAS:Mifepristone methochloride is a glucocorticoid antagonist. This product will be sold for research use only.Formula:C30H38ClNO2Color and Shape:SolidMolecular weight:480.08JAK-2/3-IN-3
JAK-2-/3-IN-3 (ST4j) is a potent JAK2/3 inhibitor for leukemia research, with IC50s: JAK2, 13 nM; JAK3, 14.86 nM; induces apoptosis.Formula:C13H10Cl2N4O2Color and Shape:SolidMolecular weight:325.15KRAS G12C inhibitor 15
CAS:KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .Formula:C25H21ClF2N4O3Purity:98%Color and Shape:SolidMolecular weight:498.91AT1R antagonist 2
AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).Formula:C29H37N5O4S2Color and Shape:SolidMolecular weight:583.77Antimalarial agent 7
Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.Formula:C23H22F2N4O3Color and Shape:SolidMolecular weight:440.44CXCR4 probe 1
CAS:CXCR4 probe 1, a specific PET tracer, targets CXCR4 with antagonist TN14003 (IC50: 6.9 nM), aiding in imaging CXCR4-related diseases and tumors.Formula:C24H30FN5O4SColor and Shape:SolidMolecular weight:502.59(-)-Cevimeline hydrochloride hemihydrate
(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.785(S),6(R)-DiHETE
CAS:5(S),6(R)-DiHETE is a dihydroxy fatty acid from LTA4 hydrolysis and weak LTD4 agonist with ED50 of 1.3 μM for guinea pig ileum contraction.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47Namitecan
CAS:Namitecan is an effective inhibitor of topoisomerase I. It has antitumor property.Formula:C23H22N4O5Purity:98%Color and Shape:SolidMolecular weight:434.44Seco-Duocarmycin SA
CAS:Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.Formula:C25H24ClN3O7Purity:98%Color and Shape:SolidMolecular weight:513.93LY 235959
CAS:LY 235959 is a NMDA receptor antagonist.Formula:C11H20NO5PPurity:98%Color and Shape:SolidMolecular weight:277.25TMX-4113
TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1α(CK1α) degrader [1].Formula:C12H12N4O2S2Color and Shape:SolidMolecular weight:308.38ATM Inhibitor-4
ATM Inhibitor -4: selective, potent (IC50: 0.32 nM), inhibits PI3K family, stable, stops mTOR at 1 μM.Formula:C26H29FN6O3Color and Shape:SolidMolecular weight:492.55Topoisomerase I/II inhibitor 3
Topoisomerase I/II inhibitor 3 suppresses cell growth and induces apoptosis in liver cancer by blocking PI3K/Akt/mTOR.Formula:C24H24N2O4Color and Shape:SolidMolecular weight:404.46GP-1681
CAS:GP-1681, a G-protein coupled receptor (GPCR) agonist, is used potentially for the treatment of influenza infection.Formula:C24H30NaO5Purity:98%Color and Shape:SolidMolecular weight:421.48SF0166
CAS:SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.Formula:C23H27F2N5O4Color and Shape:SolidMolecular weight:475.49GSK579289A
CAS:GSK579289A is an inhibitor of benzimidazole thiophene.Formula:C26H27ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:511.04Tezampanel hydrate
CAS:Tezampanel is used for the treatment of migraine, neuropathic pain.Formula:C13H23N5O3Color and Shape:SolidMolecular weight:297.35Dihydrophaseic acid
CAS:Dihydrophaseic acid 3'-O-b-D-glucopyranoside (D3G) can increase the proliferation and differentiation of osteoblast cells and enhance bone formation, suggestsFormula:C15H22O5Purity:98%Color and Shape:SolidMolecular weight:282.33KUSC-5037
KUSC-5037 inhibits HIF-1 (IC50 = 1.2 μM) and mitochondrial complex V/FoF1ATP synthase.Formula:C18H17F3N6O2Color and Shape:SolidMolecular weight:406.13651DIDS
CAS:DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.Formula:C16H10N2O6S4Purity:98%Color and Shape:SolidMolecular weight:454.52PI3K-IN-35
CAS:PI3K-IN-35 (6l) selectively inhibits PI3K-α, β, δ (IC50: 13.98, 7.22, 10.94 μM), blocks G2/M phase, induces apoptosis, and is useful in leukemia research.Formula:C25H23N7O2Color and Shape:SolidMolecular weight:453.5MIV-150
CAS:MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).Formula:C19H17FN4O3Purity:98%Color and Shape:SolidMolecular weight:368.36p38-α MAPK-IN-5
CAS:p38-α MAPK-IN-5: potent p38α inhibitor, IC50s: 0.1 nM (α), 0.2 nM (β), 944 nM (γ), 4100 nM (δ); anti-inflammatory, promising for asthma/COPD research.Formula:C37H49N11O2Color and Shape:SolidMolecular weight:679.86KMH-233
CAS:KMH-233 effectively blocks LAT1, inhibiting L-leucine uptake and cell growth, boosting betastatin and cisplatin efficacy at 25 μM.Formula:C32H25N7O5Color and Shape:SolidMolecular weight:587.58DI-404
CAS:DI-404: Potent DCN1-UBC12 inhibitor, selectivity blocks cullin 3 neddylation, Kd=6.9 nM.Formula:C35H45ClN6O6SPurity:98%Color and Shape:SolidMolecular weight:713.29MK-8825
CAS:MK-8825 is a CGRP receptor antagonist.Formula:C31H30F2N6O3Color and Shape:SolidMolecular weight:572.61Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formula:C16H11F2N3Color and Shape:SolidMolecular weight:283.28ETX0282
CAS:ETX0282, oral class A/C β-lactamase inhibitor, developed by Entasis with cefpodoxime for bacterial infections.Formula:C13H18FN3O5Color and Shape:SolidMolecular weight:315.30HDAC1-IN-5
HDAC1-IN-5 inhibits HDAC1 (IC50=15 nM) & HDAC6 (IC50=20 nM), promotes apoptosis, damages chromatin, and reduces tumor growth in mice.Formula:C20H21N3O2SColor and Shape:SolidMolecular weight:367.46HBV-IN-20
HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).Color and Shape:SolidAntiangiogenic agent 2
Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.
Formula:C26H26FN3O4Color and Shape:SolidMolecular weight:463.5Soyacerebroside II
CAS:Soyacerebroside II is a Ca2+ ionophore; both I and II inhibit IL-18 in PBMCs and modulate immune responses.Formula:C40H75NO9Purity:98%Color and Shape:SolidMolecular weight:714.02KR-67607
CAS:KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.Formula:C24H29Cl2F3N4O4SColor and Shape:SolidMolecular weight:597.48MRK003
CAS:MRK003, a γ-secretase inhibitor, induces apoptosis, halts cell growth in myeloma/NHL, and affects notch signaling and PI3K/Akt pathway.Formula:C25H31F6N3O2SColor and Shape:SolidMolecular weight:551.59SARS-CoV-2-IN-23
SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].Formula:C21H22N2OColor and Shape:SolidMolecular weight:318.41Bulgecin A
CAS:Bulgecin A is an inhibitor of binuclear metallo-beta-lactamases and Lytic transglycosolase.Formula:C16H29N3O14S2Color and Shape:SolidMolecular weight:551.54DS01080522
DS01080522: PRKACA inhibitor, IC50: kinase 0.8 nM, CREB 66 nM; potential for cancer research.Formula:C23H20Cl2N4O3Color and Shape:SolidMolecular weight:471.34Tylophorinidine
CAS:Tylophorinidine is an antifungal agent that has shown to inhibit cell growth.Formula:C22H23NO4Color and Shape:SolidMolecular weight:365.42FMK-MEA
CAS:FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.Formula:C21H26FN5O2Purity:98%Color and Shape:SolidMolecular weight:399.46ATR-IN-14
CAS:ATR-IN-14: potent ATR kinase inhibitor; 98.03% inhibition at 25 nM; IC50 of 64 nM in LoVo cells.Formula:C20H20FN7OColor and Shape:SolidMolecular weight:393.42AQX-435
CAS:AQX-435 activates SHIP1, inhibits PI3K in BCR signaling, induces apoptosis in B cells, and slows lymphoma growth.Formula:C27H34N2O4Color and Shape:SolidMolecular weight:450.57Antiproliferative agent-3
Antiproliferative agent-3 (comp 4) exhibits potent growth inhibitory effects against MCF-7 cells with IC 50 of 0.19 nM [1].Formula:C11H12N2O5SColor and Shape:SolidMolecular weight:284.29LY 245769
CAS:LY 245769 is an inhibitor of leukotriene E4 (LTE4).Formula:C25H33F3N8OSPurity:98%Color and Shape:SolidMolecular weight:550.64BXL0124
CAS:BXL0124 is a gemini vitamin D analog which targets CD44-STAT3 signaling and inhibits breast cancer invasion.Formula:C32H44F6O4Color and Shape:SolidMolecular weight:606.68
