Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,754 products)
- Apoptosis(6,185 products)
- Cell Cycle/Checkpoint(4,805 products)
- Chromatin/Epigenetics(2,573 products)
- Cytoskeletal Signaling(1,502 products)
- DNA Damage/DNA Repair(2,893 products)
- Endocrinology/Hormones(3,702 products)
- Enzyme(3,671 products)
- GPCR/G-Protein(8,963 products)
- Immunology and Inflammation(3,697 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(414 products)
- MAPK Signaling(1,246 products)
- Membrane Transporter/Ion Channel(3,136 products)
- Metabolism(10,098 products)
- Microbiology/Virology(7,552 products)
- Neuroscience(10,304 products)
- Other Inhibitors(35,769 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,402 products)
- Proteases/Proteasome(1,670 products)
- Stem Cell and Derivatives(742 products)
- Tyrosine Kinase/Adaptors(1,923 products)
- Ubiquitination(1,715 products)
Show 16 more subcategories
Found 66573 products of "Inhibitors"
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ZIKV-IN-4
ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 μM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase.Formula:C33H37NO4Color and Shape:SolidMolecular weight:511.65Human carbonic anhydrase II-IN-1
Compound S-13: Potent hCA II inhibitor, Kis 4.4, 9.2, 480.2, 14.7 nM for hCA II, I, IV, IX. Used in glaucoma research.Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5BACE1-IN-8
BACE1-IN-8 is a potent inhibitor of BACE1 (β-site APP lyase 1) (IC50: 3.9 μM).Formula:C29H45N5O7Color and Shape:SolidMolecular weight:575.7LSD1-IN-15
LSD1-IN-15 inhibits LSD1, MAO-A/B with IC50s: 0.149, 0.028, 0.327 μM; arrests LNCaP cancer cell growth, IC50 9.9 μM.Formula:C22H20N2OColor and Shape:SolidMolecular weight:328.41FAAH/MAGL-IN-1
FAAH/MAGL-IN-1 (SIH 3) inhibits FAAH & MAGL with IC50 of 31 & 29 nM, useful in neuropathic pain research.Formula:C15H9Cl2N3O3Color and Shape:SolidMolecular weight:350.16WAY-855
CAS:WAY-855 is an EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake.Formula:C9H11NO4Color and Shape:SolidMolecular weight:197.19T01-1
CAS:T01-1, a derivative of camptothecin, is an anticancer agent demonstrating significant anti-proliferative activity.Formula:C26H29N3O6SColor and Shape:SolidMolecular weight:511.59HDAC-IN-34
HDAC-IN-34 inhibits HDAC1 (IC50: 0.022 μM) & HDAC6 (IC50: 0.45 μM), binds DNA causing damage, and halts HCT-116 cell growth (IC50: 1.41 μM).Formula:C24H26N6O3Color and Shape:SolidMolecular weight:446.5Tauro-ω-muricholic acid sodium
Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid of hepatic origin.Formula:C26H44NNaO7SColor and Shape:SolidMolecular weight:537.68URAT1 inhibitor 3
URAT1 inhibitor 3: potent oral URAT1 blocker, IC50=0.8 nM, for gout/hyperuricemia study.Formula:C14H8Cl2N2O2Color and Shape:SolidMolecular weight:307.139(S)-HETE
CAS:9(S)-HETE is an enantiomer of (±)9-HETE, not an enzymatic product, and doesn't promote cell adhesion like 12(S)-HETE. Identified by chiral HPLC.Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47MRS-2339
CAS:MRS-2339 is a P2X receptor activator.Formula:C12H15ClN5O6PColor and Shape:SolidMolecular weight:391.70MAO A/HDAC-IN-1
MAO A/HDAC-IN-1 is an effective monoamine oxidase A (MAO A) and HDAC dual inhibitor, which can be used for glioma research.Formula:C21H24ClN3O3Color and Shape:SolidMolecular weight:401.89Antibiotic MA 144M1
CAS:Antibiotic MA 144M1, an anthracycline, targets gram-positive bacteria and animal tumors; derived from Streptomyces fermentation or aclacinomycin A conversion.Formula:C42H55NO15Color and Shape:SolidMolecular weight:813.88CB2 receptor antagonist 1
CAS:Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.Formula:C28H47NO3Color and Shape:SolidMolecular weight:445.68FXIa-6f
CAS:FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical speciesFormula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04Indinavir monohydrate
CAS:Indinavir monohydrate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.Formula:C36H49N5O5Color and Shape:SolidMolecular weight:631.82AFP-07
CAS:AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.Formula:C22H29F2NaO5Purity:98%Color and Shape:SolidMolecular weight:434.45PTP1B-IN-21
PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.Formula:C22H22O11Color and Shape:SolidMolecular weight:462.4Tubulin polymerization-IN-34
"Tubulin-IN-34 inhibits oxazolylisoindole microtubule assembly, selective for VL51 lymphoma."Formula:C31H35N3O6Color and Shape:SolidMolecular weight:545.63MAO-B-IN-5
CAS:MAO-B-IN-5: potent, selective oral MAO-B inhibitor, IC50=0.204μM, potential for Parkinson's research.
Formula:C19H21FN2O2Purity:97.68%Color and Shape:SolidMolecular weight:328.38LSD1-IN-16
LSD1-IN-16 (4b) inhibits LSD1, MAO-A/B; IC50: 0.015-0.366 μM. Halts prostate cancer cell growth; IC50: 15.2 μM.Formula:C20H18N2OSColor and Shape:SolidMolecular weight:334.43CS-003 Free base
CAS:CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.Formula:C34H38Cl2N2O6SPurity:98%Color and Shape:SolidMolecular weight:673.65Enpp-1-IN-7
Enpp-1-IN-7: potent enpp-1 inhibitor, broad specificity, potential in cancer/infectious disease research. (WO2021203772A1)Formula:C18H19N7O4SColor and Shape:SolidMolecular weight:429.45FGFR4-IN-9
FGFR4-IN-9 is a selective inhibitor of FGFR4 (IC50: 75.3 nM) that effectively inhibits the growth and angiogenesis of hepatocellular carcinoma cells.Formula:C24H22ClF3N4O4Color and Shape:SolidMolecular weight:522.9Lometrexol disodium
CAS:Lometrexol disodium: Inhibits hSHMT1/2 and GARFT, anticancer by blocking purine synthesis, induces apoptosis and cell cycle arrest.Formula:C21H23N5Na2O6Color and Shape:SolidMolecular weight:487.424JAK2/FLT3-IN-1 TFA
JAK2/FLT3-IN-1 (TFA), an oral JAK2/FLT3 inhibitor, shows anticancer properties; IC50: JAK2 (0.7 nM), FLT3 (4 nM), JAK1 (26 nM), JAK3 (39 nM).Formula:C27H35F4N7O3Color and Shape:SolidMolecular weight:581.61KY-02327 acetate
KY-02327 acetate inhibits Dvl-CXXC5, stabilizes Wnt/β-catenin signaling, and enhances osteoblast differentiation.Formula:C22H31N3O6Color and Shape:SolidMolecular weight:433.5Tabimorelin hemifumarate
CAS:orally active ghrelin receptor (GHS-R1a) agonistFormula:C32H40N403C4H404Purity:98%Color and Shape:SolidMolecular weight:586.72CA IX-IN-1
CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.Formula:C16H22N4O8SColor and Shape:SolidMolecular weight:430.43KRAS G12C inhibitor 56
CAS:KRAS G12C inhibitor 56, a powerful inhibitor of SOS1 with an inhibitory concentration (IC50) of 1.6 nM, holds promise for use in cancer research.Formula:C32H39N7O4SColor and Shape:SolidMolecular weight:617.76Motuporin
CAS:Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).Formula:C40H57N5O10Color and Shape:SolidMolecular weight:767.915-HT7R antagonist 1
5-HT7R antagonist 1 is a G protein-biased antagonist with Ki of 6.5 nM for 5-HT 7R.Formula:C14H18Cl2N4Color and Shape:SolidMolecular weight:313.23Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Formula:C8H11N3O3SPurity:98%Color and Shape:SolidMolecular weight:229.26Sesamodil
CAS:Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.Formula:C29H32N2O6SPurity:98.87% - 99.87%Color and Shape:SolidMolecular weight:536.64Leu-AMS R enantiomer
CAS:Leu-AMS R enantiomer is the R enatiomer of Leu-AMS. Leu-AMS is a potent leucyl-tRNA synthetase (LRS) inhibitor that inhibits the bacteria growth.Formula:C16H25N7O7SPurity:98%Color and Shape:SolidMolecular weight:459.48G247
G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.Formula:C24H19Cl2FO3Color and Shape:SolidMolecular weight:445.31BPTF-IN-BZ1
CAS:BPTF-IN-BZ1 is a BPTF inhibitor that possesses a high potency with a Kd of 6.3 nM.Formula:C13H15ClN4OColor and Shape:SolidMolecular weight:278.74G-9791
CAS:G-9791 is an effective and selective inhibitor of group-I PAK.Formula:C26H26ClFN6O2Purity:98%Color and Shape:SolidMolecular weight:508.98Galectin-8-IN-1
Galectin-8-IN-1 selectively binds galectin-8N with 48 μM affinity, 15x more than galectin-3.Formula:C16H18N2O6Color and Shape:SolidMolecular weight:334.32SML-10-70-1
CAS:SML-10-70-1 is a Novel Active Site Inhibitor of Oncogenic K-Ras G12C.Formula:C25H42ClN7O13P2Color and Shape:SolidMolecular weight:746.04MS8511
CAS:MS8511: Selective, irreversible G9a/GLP inhibitor. IC50: 100 nM (G9a), 140 nM (GLP). Lowers H3K9me2, anti-proliferative. Useful in cancer/AD/PWS research.Formula:C28H41N5O3Color and Shape:SolidMolecular weight:495.66DNDI-8219
CAS:DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.Formula:C13H10F3N3O5Color and Shape:SolidMolecular weight:345.23PqsR-IN-1
PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.Formula:C17H18ClN3OSColor and Shape:SolidMolecular weight:347.86CXCR2 antagonist 5
CXCR2 antagonist 5 (compound 25) binds strongly (IC50=0.013μM) and mobilizes calcium (IC50=0.1μM).
Formula:C15H14F2N4O2SColor and Shape:SolidMolecular weight:352.36Lafadofensine (D-(-)-Mandelic acid)
Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.Formula:C32H32F2N2O6Color and Shape:SolidMolecular weight:578.6Massarilactone H
CAS:Massarilactone H, a polyketide, is a neuraminidase inhibitor, with an IC 50 of 8.18 µM .Formula:C11H12O5Color and Shape:SolidMolecular weight:224.21HBV-IN-24
HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.Formula:C23H27NO6Color and Shape:SolidMolecular weight:413.46JAK-IN-23
"JAK-IN-23: oral dual JAK/STAT & NF-κB inhibitor; JAK1 (IC50: 8.9 nM), JAK2 (15 nM), JAK3 (46.2 nM); for IBD research."Formula:C23H22Cl2N4OColor and Shape:SolidMolecular weight:441.35DMGF
CAS:DMGF, a biflavonoid from Taxus, induces apoptosis, autophagy, and inhibits B16F10 cell motility and MMP-2 expression, hindering melanoma metastasis.Formula:C32H22O10Color and Shape:SolidMolecular weight:566.51
