Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,749 products)
- Apoptosis(6,182 products)
- Cell Cycle/Checkpoint(4,805 products)
- Chromatin/Epigenetics(2,571 products)
- Cytoskeletal Signaling(1,499 products)
- DNA Damage/DNA Repair(2,896 products)
- Endocrinology/Hormones(3,702 products)
- Enzyme(3,671 products)
- GPCR/G-Protein(8,962 products)
- Immunology and Inflammation(3,694 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(414 products)
- MAPK Signaling(1,246 products)
- Membrane Transporter/Ion Channel(3,135 products)
- Metabolism(10,102 products)
- Microbiology/Virology(7,552 products)
- Neuroscience(10,303 products)
- Other Inhibitors(35,763 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,400 products)
- Proteases/Proteasome(1,670 products)
- Stem Cell and Derivatives(742 products)
- Tyrosine Kinase/Adaptors(1,922 products)
- Ubiquitination(1,715 products)
Show 16 more subcategories
Found 66575 products of "Inhibitors"
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WDR5-IN-5
CAS:WDR5-IN-5: Selective oral inhibitor for WDR5's WIN site with high affinity (Ki<0.02 nM) and anti-cancer properties. Good pharmacokinetics.Formula:C29H29F3N6OColor and Shape:SolidMolecular weight:534.58Tonapofylline
CAS:Tonapofylline, orally active, selectively blocks A1 adenosine receptor (Ki: 7.4 nM), used in heart failure research.Formula:C22H32N4O4Purity:98.57%Color and Shape:SolidMolecular weight:416.51TP-6076
CAS:TP-6076 is a fluorocycline antibiotic, inhibiting bacterial protein synthesis, exhibiting great antimicrobial activity against carbapenem-resistant A.Formula:C28H32F3N3O7Color and Shape:SolidMolecular weight:579.56GDC-6036-NH
CAS:GDC-6036-NH is a precursor of compound 17a /b, which is a RAS inhibitor that can be used in cancer research.Formula:C26H30ClF4N7OPurity:99.84%Color and Shape:SolidMolecular weight:568.01NK1 receptor antagonist 2
CAS:NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research.Formula:C31H35F7N4O2Color and Shape:SolidMolecular weight:628.62RORγt inverse agonist 29
RORγt inverse agonist 29 is a potent, selective, orally active RORγt inverse agonist with an IC50 value of 21 nM.Formula:C25H24N2O5SColor and Shape:SolidMolecular weight:464.53CAII-IN-1
CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.Formula:C19H21FN4SColor and Shape:SolidMolecular weight:356.46hCA IX-IN-1
hCA IX-IN-1 inhibits human carbonic anhydrases I, II, IX, and XII with Ki values of 331.4, 28.4, 9.4, 17.8 nM and exhibits anticancer properties.Formula:C19H18N2O3SColor and Shape:SolidMolecular weight:354.42Nrf2/HO-1 activator 2
Compound 13m, a difluoro derivative, activates Nrf2/HO-1, showing neuroprotective and antioxidant effects, useful in PD research.Formula:C20H16F2O5Color and Shape:SolidMolecular weight:374.33CDK9-IN-11
CAS:CDK9-IN-11 is a potent CDK9 inhibitor that is the ligand for the PROTAC CDK9 Degrader-1 [1].Formula:C20H25N3O4Purity:98%Color and Shape:SolidMolecular weight:371.43Pexacerfont
CAS:Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).Formula:C18H24N6OPurity:99.77%Color and Shape:SolidMolecular weight:340.42Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Formula:C24H25N3O6Color and Shape:SolidMolecular weight:451.47Protease-Activated Receptor-1 antagonist 2
Selective, orally active PAR-1 antagonist with an IC50 of 7 nM, potential for cardiovascular disease studies.Color and Shape:SolidSARS-CoV-2 nsp3-IN-1
Compound 15c selectively inhibits SARS-CoV-2 nsp3 Mac1 with IC50 of 6.1 μM.Formula:C17H15N5O2Color and Shape:SolidMolecular weight:321.33MEN-10354
CAS:MEN-10354 is a less potent and less selective NK-2 tachykinin receptor antagonist compared to the linear analog, R 396.Formula:C37H46N8O9Color and Shape:SolidMolecular weight:746.81Anti-inflammatory agent 13
Pentacyclic triterpene, Anti-inflammatory 13 inhibits DAMP/PAMP inflammation models.Formula:C30H48O4Color and Shape:SolidMolecular weight:472.7FLT3/TrKA-IN-1
FLT3/TrKA-IN-1: Potent dual kinase inhibitor for FLT3 & TrKA, promising for AML research.Formula:C28H30N4O2Color and Shape:SolidMolecular weight:454.56HSP90-IN-11
HSP90-IN-11: potent HSP90 inhibitor, akin to AUY-922; hinders CRC/NSCLC cell proliferation; degrades EGFR, Akt proteins.Formula:C27H30FN3O6Color and Shape:SolidMolecular weight:511.54Urease-IN-2
Urease-IN-2 is a non-competitive inhibitor of urease (IC50: 0.94 μM, Ki: 1.6 μM) that non-competitively inhibits Jack bean urease (JBU).Formula:C26H25N5O5S3Color and Shape:SolidMolecular weight:583.7ZD6021
CAS:ZD6021 is an antagonist of neurokinin 1 receptor.Formula:C35H35Cl2N3O2SPurity:98%Color and Shape:SolidMolecular weight:632.64S-1033
CAS:S-1033 is an FP receptor agonist.Formula:C20H33NaO4Color and Shape:SolidMolecular weight:360.4698CM-352
CAS:CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.Formula:C24H29N3O6SPurity:97.24%Color and Shape:SolidMolecular weight:487.57CM-414
CAS:CM-414: HDAC/PDE5 inhibitor, targeting Alzheimer’s, IC50s: PDE5 (60 nM), HDAC1/2/3/6. Reduces Aβ, pTau in mice, boosts cognition.Formula:C23H29N5O4Purity:98%Color and Shape:SolidMolecular weight:439.51TAS-117 hydrochloride
TAS-117 HCl: potent oral Akt inhibitor (Akt1 IC50: 4.8nM, Akt2: 1.6nM, Akt3: 44nM), boosts anti-myeloma effects, induces cell death.Formula:C26H25ClN4O2Color and Shape:SolidMolecular weight:460.96CP-481715
CAS:CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.Formula:C26H31FN4O4Color and Shape:SolidMolecular weight:482.55SLN124
SLN124, a GalNAc-siRNA targeting TMPRSS6, may normalize iron balance by restoring ferroregulation.Color and Shape:SolidLHC-165
CAS:LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.Formula:C29H32F2N3O7PPurity:98%Color and Shape:SolidMolecular weight:603.55ACHN-975
CAS:ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Formula:C20H23N3O4Purity:98%Color and Shape:SolidMolecular weight:369.41NYX-2925
CAS:NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.Formula:C14H23N3O4Color and Shape:SolidMolecular weight:297.35Ivaltinostat formic
Ivaltinostat (CG-200745) is an oral panHDAC inhibitor, inducing apoptosis and enhancing cancer drug sensitivity.Formula:C25H35N3O6Color and Shape:SolidMolecular weight:473.56TLR7/8 agonist 7
CAS:TLR7/8 agonist 7 activates immune cells, useful in ISAC synthesis and immunity research.Formula:C26H37N7O2Color and Shape:SolidMolecular weight:479.62HDAC-IN-37
HDAC-IN-37 inhibits HDACs 1, 3, 8, & 6, induces histone acetylation, halts G1 to S phase, and triggers early apoptosis.Formula:C23H24ClN7OColor and Shape:SolidMolecular weight:449.94EBOV-GP-IN-1
EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).Formula:C25H40ClN3O2Color and Shape:SolidMolecular weight:450.06NA 0346
CAS:NA 0346 is a derivative of SF 2370 that shows long lasting antihypertensive action as well as potent protein kinases inhibitory activity.Formula:C26H22N4O3Color and Shape:SolidMolecular weight:438.48Onfasprodil
CAS:Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)Formula:C20H23FN2O3Color and Shape:SolidMolecular weight:358.4116,16-Dimethyl prostaglandin E2
CAS:16,16-Dimethyl prostaglandin E2 regulates hematopoietic stem cells via EP2/EP4 and Wnt, taken orally.Formula:C22H36O5Purity:98%Color and Shape:SolidMolecular weight:380.52Anticancer agent 14
Anticancer agent 14: a potent breast cancer inhibitor; induces cell death, disrupts mito. membrane potential (IC50: 0.20-0.65 μM).Formula:C29H34N2O3Color and Shape:SolidMolecular weight:458.59SBI-581
SBI-581: oral, potent TAO3 inhibitor, IC50=42nM, alters TKS5α at RAB11+ vesicles, blocks invadopodia, good mouse pharmacokinetics, anti-tumor.Formula:C24H21N3O2Color and Shape:SolidMolecular weight:383.44P-gp modulator 2
P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.Formula:C22H20BrN3O4Color and Shape:SolidMolecular weight:470.32Tandutinib (MLN518) HCl
Tandutinib antagonizes FLT3, PDGFR, and c-Kit with an IC50 of ~200 nM.Formula:C31H43ClN6O4Purity:98%Color and Shape:SolidMolecular weight:599.16Geissoschizoline
CAS:Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42ERα degrader 5
ERα degrader 5 is an orally active, selective estrogen receptor (ER) reducer that acts on ERα (EC50: 1.1 nM). ERα degrader 5 shows anti-tumour effects in vivo.Formula:C29H25F4N3O2SColor and Shape:SolidMolecular weight:555.59MK-6913
CAS:MK-6913 is a potent and selective agonist of estrogen receptor β.Formula:C25H27N3O2Purity:98%Color and Shape:SolidMolecular weight:401.5PCSK9-IN-17
CAS:PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.Formula:C16H19N5OSColor and Shape:SolidMolecular weight:329.42MRS4738
MRS4738 is a potent antagonist with high affinity for the P2Y14R receptor. It demonstrates in vivo anti-hyperallodynic and antiasthmatic activity [1].Formula:C30H24F3NO2Color and Shape:SolidMolecular weight:487.51K027
K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.Formula:C15H18Br2N4O2Color and Shape:SolidMolecular weight:446.1412(S)-HETE
CAS:Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.
Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47ATR-IN-17
CAS:ATR-IN-17 is a potent inhibitor of ATR kinase with good anti-cancer effects in LoVo cells (IC50: 1 nM).Formula:C22H28N6O2SColor and Shape:SolidMolecular weight:440.56FNDR-20123
FNDR-20123: First safe, effective anti-malarial HDAC inhibitor for Plasmodium (IC50: 31 nM) & human HDACs, with nanomolar potency across several subtypes.Formula:C21H24ClN5O2Color and Shape:SolidMolecular weight:413.9Cortistatin A
CAS:Cortistatin A is a potent and selective mediator-associated kinase CDK8 and its paralogue CDK19 inhibitor.Formula:C30H36N2O3Purity:98%Color and Shape:SolidMolecular weight:472.62
