Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,754 products)
- Apoptosis(6,185 products)
- Cell Cycle/Checkpoint(4,805 products)
- Chromatin/Epigenetics(2,573 products)
- Cytoskeletal Signaling(1,502 products)
- DNA Damage/DNA Repair(2,893 products)
- Endocrinology/Hormones(3,702 products)
- Enzyme(3,671 products)
- GPCR/G-Protein(8,963 products)
- Immunology and Inflammation(3,697 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(414 products)
- MAPK Signaling(1,246 products)
- Membrane Transporter/Ion Channel(3,136 products)
- Metabolism(10,098 products)
- Microbiology/Virology(7,552 products)
- Neuroscience(10,304 products)
- Other Inhibitors(35,769 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,402 products)
- Proteases/Proteasome(1,670 products)
- Stem Cell and Derivatives(742 products)
- Tyrosine Kinase/Adaptors(1,923 products)
- Ubiquitination(1,715 products)
Show 16 more subcategories
Found 66573 products of "Inhibitors"
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Minnelide
CAS:Minnelide is a prodrug of triptolide,and shows potent antitumor activity in a number of tumor types.Formula:C21H25Na2O10PPurity:98.49% - 99.59%Color and Shape:SolidMolecular weight:514.37Eprociclovir Na
CAS:Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.Formula:C11H14N5NaO3Color and Shape:SolidMolecular weight:287.25Dinordrin I diacetate
CAS:Dinordrin I diacetate is an implantation inhibitor and hormone.Formula:C25H32O4Purity:98%Color and Shape:SolidMolecular weight:396.52PLAP-IN-1
CAS:PLAP-IN-1: Potent, selective inhibitor of PLAP, IC50 of 32 nM; doesn't notably inhibit TNAP.Formula:C25H21Cl2N3O5Color and Shape:SoildMolecular weight:514.36CCR5 antagonist 1
CAS:CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.Formula:C39H46ClF2N5O3SPurity:98%Color and Shape:SolidMolecular weight:738.33Iloprost
CAS:Iloprost (Ciloprost) is an inhibitor of platelet aggregation and vasodilatation used in the study of cardiovascular disease.Formula:C22H32O4Color and Shape:Colorless OilMolecular weight:360.49HIF-1α-IN-5
HIF-1α-IN-5 is an inhibitor of HIF-1α with an IC 50 value of 24 nM in HEK293T cells that also inhibits the activity of MAO-A.Formula:C16H15N3O2Color and Shape:SolidMolecular weight:281.31TRPC4/5-IN-1
TRPC4/5-IN-1, a TRPC5/4 inhibitor with IC50s 0.54 μM/2.06 μM, targets skin inflammation and proteinuric kidney diseases.Formula:C21H21N3OColor and Shape:SolidMolecular weight:331.41Cryptopleurine
CAS:Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.Formula:C24H27NO3Purity:98%Color and Shape:SolidMolecular weight:377.48AK-295
CAS:AK 295, also known as CX 295, is a dipeptide inhibitor of alpha-ketoamide calpain.Formula:C26H40N4O6Color and Shape:SolidMolecular weight:504.62Purine phosphoribosyltransferase-IN-2
Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17JTZ-951 HCl
CAS:JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).Formula:C17H17ClN4O4Purity:98%Color and Shape:SolidMolecular weight:376.79Antileishmanial agent-5
Antileishmanial agent-4, a ribonucleoside analogue, targets L.infantum and T.cruzi with EC50s of 0.68 μM and 0.83 μM.Formula:C17H17ClN4O4Color and Shape:SolidMolecular weight:376.79Udifitimod
CAS:Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.Formula:C25H33NO2Color and Shape:SolidMolecular weight:379.54Emtricitabine triphosphate
CAS:Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formula:C8H13FN3O12P3SColor and Shape:SolidMolecular weight:487.19Anticancer agent 14
Anticancer agent 14: a potent breast cancer inhibitor; induces cell death, disrupts mito. membrane potential (IC50: 0.20-0.65 μM).Formula:C29H34N2O3Color and Shape:SolidMolecular weight:458.59LY 215490
CAS:LY 215490 is a selective AMPA receptor antagonist with neuroprotective properties in rat ischemia.Formula:C13H21N5O2Purity:98%Color and Shape:SolidMolecular weight:279.34Anti-inflammatory agent 18
Anti-inflammatory agent 18: NO activity blocker (IC50: 15.94 μM), hampers HMGB1-induced inflammation, potential for COVID-19, sepsis study.Formula:C30H50O6Color and Shape:SolidMolecular weight:506.71LY3130481
CAS:LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44Cbl-b-IN-1
CAS:Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.Formula:C29H34N6O2Purity:99.68%Color and Shape:SolidMolecular weight:498.631BM635 mesylate (1493762-74-5 free base)
BM635 mesylate is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).Formula:C26H33FN2O4SPurity:98%Color and Shape:SolidMolecular weight:488.61Ro 31-8472
CAS:Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat.Formula:C20H27N3O6Purity:98%Color and Shape:SolidMolecular weight:405.44Antifungal agent 40
Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.Formula:C22H20Cl2N4SeColor and Shape:SolidMolecular weight:490.29AMG-548 hydrochloride
AMG-548 hydrochloride: orally active, p38α inhibitor (Ki=0.5 nM), 1000x less for p38γ/δ, also blocks TNFα (IC50=3 nM) & inhibits casein kinase 1 δ/ε.Formula:C29H28ClN5OColor and Shape:SolidMolecular weight:498.02LXRβ agonist-2
CAS:LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM.Formula:C32H31F6N3O7Purity:98%Color and Shape:SolidMolecular weight:683.59GSD-11
GSD-11: Potent, selective anti-austerity agent; blocks Akt/mTOR pathway, hinders PANC-1 cell migration & colony growth. Promising for pancreatic cancer study.Formula:C20H28O2Color and Shape:SolidMolecular weight:300.44BMS-554417
CAS:BMS-554417 inhibits IGF-IR/insulin receptors, curbing cell proliferation and tumor growth, with IC50 values of 120 nm–>8.5 μmol/L.Formula:C28H30ClN7O2Color and Shape:SolidMolecular weight:532.04Dehydrocrenatidine
CAS:Dehydrocrenatidine (Kumujian G) is an inhibitor of JAK and induces cell apoptosis.Formula:C15H14N2O2Purity:98%Color and Shape:SolidMolecular weight:254.28cSPM
cSPM (Cyclic spermine) is an Aβ42 inhibitor. cSPM inhibits the aggregation of three different peptides, Aβ42, tryptophan and insulin, and reduces cytotoxicity.Formula:C27H57N7Color and Shape:SolidMolecular weight:479.79Anticancer agent 80
Anticancer agent 80 (Compound 3c) is an anticancer agent that exhibits a significant dark toxic effect on T47-D (IC50: 10.14 μM).Formula:C19H12BrNO5Color and Shape:SolidMolecular weight:414.21M826
M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity inFormula:C28H45N7O6Purity:98%Color and Shape:SolidMolecular weight:575.7GNE-886
CAS:GNE-886 has a wide range of applications in life science related research.Formula:C28H30N6O3Purity:98%Color and Shape:SolidMolecular weight:498.59Rostratin B
CAS:Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.Formula:C18H20N2O6S2Color and Shape:SolidMolecular weight:424.49NYX-2925
CAS:NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.Formula:C14H23N3O4Color and Shape:SolidMolecular weight:297.35YM158 free base
CAS:YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).Formula:C32H33ClN6O5S2Purity:98%Color and Shape:SolidMolecular weight:681.22TCMDC-125431
TCMDC-125431 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystals.Formula:C25H27N3O2SColor and Shape:SolidMolecular weight:433.57Brostallicin HCl
CAS:Brostallicin, a synthetic MGB, inhibits DNA replication in cancer cells, inducing cell death, effective against MMR-defective tumors.Formula:C30H36BrClN12O5Color and Shape:SolidMolecular weight:760.04LPA5 antagonist 1
LPA5 antagonist 1: selective, potent (IC50=32 nM), high brain permeability, studies inflammatory/neuropathic pain.Formula:C28H26N2O4SColor and Shape:SolidMolecular weight:486.58PDE4-IN-12
PDE4-IN-12 is a potent and safe PDE4 ubiquitous inhibitor that acts on PDE4 (IC50: 3.5 nM, SI: 2.71) and PDE7 (IC50: 15 nM, SI: 4.27).Formula:C34H35NO6Color and Shape:SolidMolecular weight:553.64(Z)-Lanoconazole
(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.
Formula:C14H10ClN3S2Color and Shape:SolidMolecular weight:319.83NNC-11-1585
CAS:NNC-11-1585 is an M(1) and M(2) muscarinic acetylcholine receptor (mAChR) agonist.Formula:C18H19N3OSColor and Shape:SolidMolecular weight:325.43CRV431
CAS:CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM).Formula:C67H122N12O13Color and Shape:SolidMolecular weight:1303.766-trans-12-epi-Leukotriene B4
CAS:6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47Utrophin modulator 1
UM1 upregulates utrophin, has EC50 of 0.11 μM, useful in DMD research.Formula:C22H18N6OColor and Shape:SolidMolecular weight:382.42Sulprostone
CAS:EP3 and EP1 receptor agonistFormula:C23H31NO7SPurity:98%Color and Shape:White To Off-White SolidMolecular weight:465.56ACT-777991
CAS:ACT-777991: oral CXCR3 blocker, stable in microsomes/hepatocytes, inhibits T-cell migration to CXCL11.Formula:C20H20F6N8O2SColor and Shape:SolidMolecular weight:550.48Antiviral agent 15
Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).Formula:C27H24FN5OColor and Shape:SolidMolecular weight:453.51Anticancer agent 64
CAS:Anticancer agent 64 (5m) induces apoptosis, has IC50 2.4μM in CCRF-CEM, activates caspases, cleaves PARP, affects mitochondria.Formula:C31H46N2O2SColor and Shape:SolidMolecular weight:510.77GT-055
GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.Formula:C13H20F3N5O8SColor and Shape:SolidMolecular weight:463.39Hymenidin
CAS:Hymenidin, isolated from the Okinawan sponge Hymeniacidon sp., is a 5-hydroxytryptaminergic receptor antagonist and voltage-gated potassium channel inhibitor.Formula:C11H12BrN5OPurity:96.85% - 99.52%Color and Shape:SolidMolecular weight:310.15
