Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,799 products)
- Apoptosis(6,261 products)
- Cell Cycle/Checkpoint(4,840 products)
- Chromatin/Epigenetics(2,595 products)
- Cytoskeletal Signaling(1,537 products)
- DNA Damage/DNA Repair(2,878 products)
- Endocrinology/Hormones(3,748 products)
- Enzyme(3,671 products)
- GPCR/G-Protein(8,988 products)
- Immunology and Inflammation(3,803 products)
- Influenza Virus(299 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,252 products)
- Membrane Transporter/Ion Channel(3,149 products)
- Metabolism(10,143 products)
- Microbiology/Virology(7,592 products)
- Neuroscience(10,347 products)
- Other Inhibitors(35,827 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,420 products)
- Proteases/Proteasome(1,683 products)
- Stem Cell and Derivatives(744 products)
- Tyrosine Kinase/Adaptors(1,960 products)
- Ubiquitination(1,724 products)
Show 16 more subcategories
Found 66561 products of "Inhibitors"
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CK2-IN-3
CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.Formula:C22H26N4O7Color and Shape:SolidMolecular weight:458.46Hypoglycemic agent 1
CAS:Hypoglycemic agent 1 has an action for lowering blood sugar. It acts as a therapeutic and/or prophylactic agent for diabetes.Formula:C25H24FN5O4Purity:98%Color and Shape:SolidMolecular weight:477.49Dihydrokainic acid
CAS:EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptakeFormula:C10H17NO4Purity:98%Color and Shape:SolidMolecular weight:215.25Ciluprevir
CAS:Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.Formula:C40H50N6O8SPurity:98%Color and Shape:SolidMolecular weight:774.93GNTI dihydrochloride
CAS:κ opioid receptor antagonistFormula:C27H30ClN5O3Purity:98%Color and Shape:SolidMolecular weight:508.01DDCPPB-Glu
CAS:DDCPPB-Glu is a 6-5 fused ring heterocycle antifolate that shows antitumor activity.Formula:C22H27N5O5Purity:98%Color and Shape:SolidMolecular weight:441.48KDOAM-25 citrate
CAS:KDOAM-25 citrate inhibits KDM5A/B/C/D (IC50: 71, 19, 69, 69 nM); boosts H3K4 methylation, hinders MM1S cell growth. [1]Formula:C21H33N5O9Purity:98%Color and Shape:SolidMolecular weight:499.51JH295 hydrate
JH295 hydrate: potent, irreversible Nek2 inhibitor (IC50 = 770 nM), selective, doesn't target Cdk1, Aurora B or Plk1.Formula:C18H18N4O3Color and Shape:SolidMolecular weight:338.36BI-4916
CAS:BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.Formula:C23H24Cl2N2O6SPurity:98.55%Color and Shape:SolidMolecular weight:527.42Trichostatin A S-isomer
CAS:Trichostatin A S-isomer, a HDAC 1, 3, 4, 6, 10 inhibitor with IC50 ~20 nM, has wide-ranging epigenetic effects.Formula:C17H22N2O3Purity:98%Color and Shape:SolidMolecular weight:302.37SGL5213
CAS:SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.Formula:C37H55N3O8Purity:98%Color and Shape:SolidMolecular weight:669.85PRMT5-IN-1 hydrochloride
PRMT5 IN-1 hydrochloride is a potent PRMT5 inhibitor (IC50: 11 nM), forms covalent adduct with C449, and converts to an aldehyde in vivo.Formula:C19H20Cl2N4O5Color and Shape:SolidMolecular weight:455.29Human carbonic anhydrase II-IN-2
Compound R-13, a potent inhibitor of hCA I/II/IV/IX with K i s of 60.7, 320.7, 2298, and 35.2 nM.Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5EGFR/HER2-IN-4
EGFR/HER2-IN-4: oral, irreversible dual EGFR inhibitor (IC50: 0.6 nM), targets L858R/T790M mutations, potent anti-lung cancer effects in vivo.Color and Shape:SolidBMS-986118
CAS:BMS-986118 is a GPR40 full agonist targeting type II diabetes, prompting insulin release without hypoglycemia risk.Formula:C25H28ClF3N4O4Purity:98%Color and Shape:SolidMolecular weight:540.96Bcl-2-IN-7
Bcl-2-IN-7 inhibits Bcl-2, encourages apoptosis in cancer cells, and has anti-tumor activity with various IC50 values.Formula:C24H22N4O5S2Color and Shape:SolidMolecular weight:510.59L 739749
CAS:L 739749 is a CAAX peptidomimetic. It is also an inhibitor of farnesyl-protein transferase.Formula:C24H41N3O6S2Purity:98%Color and Shape:SolidMolecular weight:531.73Mesulergine hydrochloride
CAS:5-HT2A and 2C receptor antagonistFormula:C18H27ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:398.95SHR2415
SHR2415: Potent, selective ERK1/2 inhibitor, oral; ERK1 IC50: 2.8 nM, ERK2 IC50: 5.9 nM; effective in Colo205 (IC50: 44.6 nM), for cancer research.Formula:C23H22ClN7O2Color and Shape:SolidMolecular weight:463.92MSA-2 dimer
CAS:MSA-2 dimer: selective oral non-nucleotide STING agonist, Kd=145 μM, long-term antitumor effect, non-covalent, higher permeability.Formula:C29H28O8S2Color and Shape:SolidMolecular weight:568.66Netupitant metabolite Monohydroxy Netupitant
CAS:Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.Formula:C30H32F6N4O2Purity:98%Color and Shape:SolidMolecular weight:594.59EGFR-IN-35
CAS:EGFR-IN-35, an acrylamide-based EGFR inhibitor, shows promise for EGFR mutation-related cancers like NSCLC.Formula:C25H24ClN7O2Color and Shape:SolidMolecular weight:489.96GW311616
CAS:GW-311616 is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).Formula:C19H31N3O4SColor and Shape:SolidMolecular weight:397.53HDAC10-IN-1
HDAC10-IN-1 is a potent, selective HDAC10 inhibitor (IC50=58 nM) affecting autophagy in FLT3-ITD+ acute myeloid leukemia cells.Formula:C18H23N3O2Color and Shape:SolidMolecular weight:313.39Pateamine A
CAS:Pateamine A: marine-sourced macrolide from Mycale hentscheli; anticancer, antiviral, and translation inhibitor.Formula:C31H45N3O4SColor and Shape:SolidMolecular weight:555.77F 14679
CAS:F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.Formula:C21H25ClF2N4OPurity:99.09%Color and Shape:SolidMolecular weight:422.9Monlunabant
CAS:Monlunabant ((S)-MRI-1891), a solid dispersion compound, functions as an inhibitor of the cannabinoid CB1 receptor [1].Formula:C26H22ClF3N6O3SPurity:98%Color and Shape:SolidMolecular weight:591.00HER2-IN-7
CAS:HER2-IN-7 is a potent HER2 inhibitor with potential for researching ErbB-related diseases, especially cancer.Formula:C28H26F3N7O3Color and Shape:SolidMolecular weight:565.55Vimirogant
CAS:Vimirogant is a RORγ inhibitor (Ki: <100 nM).Formula:C27H35F3N4O3SPurity:98%Color and Shape:SolidMolecular weight:552.65Protease-Activated Receptor-1 antagonist 2
Selective, orally active PAR-1 antagonist with an IC50 of 7 nM, potential for cardiovascular disease studies.Color and Shape:SolidhCAII-IN-4
CAS:hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.Formula:C31H23NO9Color and Shape:SolidMolecular weight:553.52Leustroducsin B
CAS:Leustroducsin B is a novel colony-stimulating factor (CSF) inducer extracted from Streptomyces platensis SANK 60191.Formula:C34H56NO10PColor and Shape:SolidMolecular weight:669.78SB-612111 hydrochloride
SB-612111 is a potent ORL-1 antagonist, with high affinity (Ki: 0.33 nM) and µ-receptor activity (Ki: 57.6 nM), blocking Nociceptin-induced pain.Formula:C24H30Cl3NOColor and Shape:SolidMolecular weight:454.86Tubulosine
CAS:Tubulosine is an anticancer agent that inhibits cancer cell growth.Formula:C29H37N3O3Color and Shape:SolidMolecular weight:475.62KRas G12C inhibitor 2
CAS:KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.Formula:C32H37N7O3Purity:98%Color and Shape:SolidMolecular weight:567.68RET-IN-7
CAS:RET-IN-7 exhibits strong inhibitory effects against RET kinase in vitro and shows significant efficacy in treating RET-driven tumor xenografts in mice throughFormula:C22H24ClFN6O2Color and Shape:SolidMolecular weight:458.92Antibacterial agent 77
Antibacterial agent 77 (compound 12) is an antibacterial agent [1].Formula:C22H27N3OSColor and Shape:SolidMolecular weight:381.53NB-216
CAS:NB-216 is a macrocyclic peptidic BACE-1 inhibitor.Formula:C35H45N3O4Color and Shape:SolidMolecular weight:571.75Domitroban
CAS:Domitroban, also known as S-145, is a thromboxane (Tx) A2-receptor antagonist with partial agonistic activity in vascular smooth muscle.Formula:C20H27NO4SColor and Shape:SolidMolecular weight:377.5Ganciclovir monophosphonate
CAS:Ganciclovir monophosphate treats CMV, inhibiting replication in human/animal strains (IC50: 0.01μM).Formula:C10H16N5O6PColor and Shape:SolidMolecular weight:333.24Aurora A inhibitor 1
CAS:Aurora A inhibitor 1: potent, selective, targets cancer-linked Aurora A overexpression, potential for cancer research. (WO2021147974A1, 49)Formula:C25H28ClF2N5O2Color and Shape:SolidMolecular weight:503.97Antitumor agent-42
Antitumor agent-42 inhibits microtubule multimerisation and NO release, exhibiting anti-angiogenic, colony-forming and apoptosis-inducing effects.Formula:C24H19BrN2O8SColor and Shape:SolidMolecular weight:575.39CRS-3123
CAS:CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.Formula:C19H19Br2N3O2SPurity:98%Color and Shape:SolidMolecular weight:513.25LpxA-IN-1
CAS:LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosaFormula:C21H11D7F3N5O3Color and Shape:SolidMolecular weight:452.44Anti-inflammatory agent 12
Pentacyclic triterpene, anti-inflammatory agent 12, inhibits LPS inflammation (IC50: 2.22 μM). May benefit inflammatory disease studies.Formula:C30H50O4Color and Shape:SolidMolecular weight:474.72Anticancer agent 36
Compound 11: Sulfonylurea derivative, antimicrobial, anticancer; MIC 0.039-0.156 mg/mL; A549 IC50: 19.7 μg/mL, PC3 IC50: 11.9 μg/mL.Formula:C21H17N3O3S2Color and Shape:SolidMolecular weight:423.51Galidesivir
CAS:Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.Formula:C11H15N5O3Purity:96.73% - 99.13%Color and Shape:SolidMolecular weight:265.27DNA-PK-IN-6
CAS:DNA-PK-IN-6 inhibits DNA-PKcs, disrupting tumor DNA repair and triggering apoptosis; enhances radiotherapy and targets various tumors (WO2021197159A1).Formula:C19H21N7OColor and Shape:SolidMolecular weight:363.42Mt KARI-IN-1
Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.Formula:C14H11N5O4S2Color and Shape:SolidMolecular weight:377.4Minnelide free acid
CAS:Minnelide treats pancreatic cancer, hinders androgen-related prostate growth, shrinks tumors, and improves survival.Formula:C21H27O10PColor and Shape:SolidMolecular weight:470.41
