Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,832 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,611 products)
- Cytoskeletal Signaling(1,563 products)
- DNA Damage/DNA Repair(2,873 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,141 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,851 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,690 products)
- Stem Cell and Derivatives(735 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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Ac-ATS010-KE
CAS:Ac-ATS010-KE is a novel Selective, irreversible, and Rapid Cell-Permeable Inhibitor of Human Caspase-3.Formula:C43H41F5N6O12SColor and Shape:SolidMolecular weight:960.88NF-κB-IN-4
NF-κB-IN-4 (compound 17) is a potent inhibitor of NF-κB pathway which can cross blood brain barrier (BBB).Formula:C18H15FN4OColor and Shape:SolidMolecular weight:322.34(R)-BAY-899
(R)-BAY-899: R-isomer, selective LH-R antagonist, effective on hLH (IC50: 185 nM) and rLH (IC50: 46 nM), orally active.Formula:C25H19F2N5O2Color and Shape:SolidMolecular weight:459.45IDO1-IN-13
IDO1-IN-13 is a potent IDO1 inhibitor (IC50: 61.6 nM, EC50: 30 nM in HeLa) that reduces kyn/trp ratio by 51% in SK-OV-3 tumors.Formula:C20H16BrN5O2SColor and Shape:SolidMolecular weight:470.34CCT369260
CAS:CCT369260 (compound 1), an orally active inhibitor targeting B-cell lymphoma 6 (BCL6), demonstrates anti-tumor efficacy with an IC50 value of 520 nM [1].Formula:C24H31ClF2N6O2Color and Shape:SolidMolecular weight:508.99MDL-27210
CAS:MDL-27210 is the ethyl ester prodrug of a potent angiotensin-converting enzyme inhibitor, MDL-27088.Formula:C27H32N2O5Color and Shape:SolidMolecular weight:464.55JTE 151A
CAS:JTE-151 is a novel RORγ inverse agonist.Formula:C26H30ClN3O5Color and Shape:SolidMolecular weight:499.99CGC 11144
CAS:CGC 11144 is a Polyamine analogue inhibit tumor growth in vitro and in vivo.Formula:C40H100Cl10N10Color and Shape:SolidMolecular weight:1075.82CDK5-IN-2
CAS:CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor that acts on CDK5/p25 (IC50: 0.2 nM) and CDK2/CycA (IC50: 23 nM).Formula:C29H28FN5OColor and Shape:SolidMolecular weight:481.56GSK864
CAS:GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).Formula:C30H31FN6O4Purity:97.07%Color and Shape:SolidMolecular weight:558.6Nepaprazole sodium
CAS:Nepaprazole Na (TY-11345), a proton pump inhibitor, may treat gastric ulcers; it reduces H+/K(+)-ATPase activity, with IC50 of 5.8-9.9 microM.Formula:C18H18N3NaO2SColor and Shape:SolidMolecular weight:363.41KNI 10033
CAS:KNI 10033 is a potent inhibitor of HIV proteaseFormula:C40H45N5O7S2Color and Shape:SolidMolecular weight:771.95VEGFR2-IN-1
CAS:VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.Formula:C22H18N6SPurity:98.15%Color and Shape:SolidMolecular weight:398.48Factor B-IN-3
CAS:Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.Formula:C24H29N3O4Color and Shape:SolidMolecular weight:423.5SSR-182289A (Free)
CAS:SSR-182289A (Free) is a thrombin inhibitor.Formula:C30H33F2N5O4SPurity:98%Color and Shape:SolidMolecular weight:597.68Iloprost
CAS:Iloprost (Ciloprost) is an inhibitor of platelet aggregation and vasodilatation used in the study of cardiovascular disease.Formula:C22H32O4Color and Shape:Colorless OilMolecular weight:360.49BTK-IN-10
CAS:BTK-IN-10 is a potent inhibitor of BTK, acting on wild-type BTK (IC50<5 nM) or mutant BTK (C481S) (IC50<5 nM).Formula:C25H24F2N4O2Color and Shape:SolidMolecular weight:450.48Laulimalide
CAS:Microtubule stabilizer; halts cancer cell growth (IC50: 3-30 nM); arrests cells in prometaphase; prevents bipolar spindle formation.Formula:C30H42O7Color and Shape:SolidMolecular weight:514.65Tilpisertib fosmecarbil
CAS:Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.Formula:C35H36ClN8O7PColor and Shape:SolidMolecular weight:747.14Enpp-1-IN-11
Enpp-1-IN-11 inhibits ENPP1 with a 45 nM Ki, is plasma stable, and has low clearance in human/mouse livers, potentially aiding cancer research.Formula:C15H15N5O3SColor and Shape:SolidMolecular weight:345.38Mu opioid receptor antagonist 3
Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.Formula:C25H28N2O4SColor and Shape:SolidMolecular weight:452.57Carnostatine
Carnostatine (SAN9812), a potent CN1 inhibitor with 11 nM K i, may boost renal carnosine to treat DN.Formula:C10H16N4O4Purity:98%Color and Shape:SolidMolecular weight:256.26Estrogen receptor antagonist 6
CAS:Estrogen receptor antagonist 6 is a potent blocker of estrogen signaling, regulating various biological effects. (Compound 166)Formula:C25H31F3N2O3Color and Shape:SolidMolecular weight:464.52BPN-15606 besylate
BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).Formula:C29H29FN6O4SColor and Shape:SolidMolecular weight:576.64TA-316
CAS:Agent induces megakaryocytes/platelets from stem cells to treat thrombopenia.Formula:C28H25BrN4O5S2Purity:98%Color and Shape:SolidMolecular weight:641.56ZLWT-37
ZLWT-37: Oral CDK inhibitor, CDK9 IC50=0.002 µM, CDK2 IC50=0.054 µM; halts HCT116 cells at G2/M, induces apoptosis.Formula:C26H30ClN5OColor and Shape:SolidMolecular weight:464GT-055
GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.Formula:C13H20F3N5O8SColor and Shape:SolidMolecular weight:463.39Squalestatin 3
CAS:Squalestatin 3 is an inhibitor of squalene synthase.Formula:C25H30O13Purity:98%Color and Shape:SolidMolecular weight:538.5Chitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFormula:C23H23N3O5Color and Shape:SolidMolecular weight:421.45MtMetAP1-IN-1
MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.Formula:C15H10BrN5O2SColor and Shape:SolidMolecular weight:404.24Suloctidil HCl
CAS:Suloctidil HCl is a peripheral vascular dilator.Formula:C20H36ClNOSColor and Shape:SolidMolecular weight:374.02PD-1/PD-L1-IN-13
PD-1/PD-L1-IN-13 is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM for PD-1/PD- L1 interaction.PD-1/PD-L1-IN-13 promotes CD8+ T-Formula:C36H34ClF2N3O9Color and Shape:SolidMolecular weight:726.12Anticancer agent 27
Anticancer agent 27 is a promising candidate for the treatment of cancer and deserves further development.Formula:C28H31NO6Color and Shape:SolidMolecular weight:477.55CLR01 sodium
CAS:CLR01 is a tweezer reducing α-synuclein in MSA, inhibits SOD1 in ALS, blocks Ebola/Zika, stabilizes proteins, and lessens mutant p53 toxicity.Formula:C42H30Na2O8P2Color and Shape:SolidMolecular weight:770.6211AY 17,605
CAS:AY 17,605 is an inhibitor of bovine heart and rat brain nucleoside-3',5'- monophosphate phosphodiesterase.Formula:C25H36O5Color and Shape:SolidMolecular weight:416.5520S Proteasome-IN-4
CAS:20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.Formula:C20H18ClF2N3O3Color and Shape:SolidMolecular weight:421.83FTI-2148
CAS:FTI-2148 blocks RAS-related FT-1 & GGT-1; IC50: 1.4 nM & 1.7 μM.Formula:C24H28N4O3SPurity:98%Color and Shape:SolidMolecular weight:452.57A1/A3 AR antagonist 1
Compound 10 is a potent dual A1/A3 AR antagonist, with Ki values of 37.6 nM (hA1), 25.4 nM (hA3), and 1.47 nM (rA1), studied in renal, lung, and Alzheimer's.Formula:C24H18N2O3SColor and Shape:SolidMolecular weight:414.48DS89002333
DS89002333: oral PRKACA inhibitor with 0.3 nM IC50, effective against FL-HCC with DNAJB1-PRKACA fusion in xenografts.Formula:C22H20ClF2N3O3Color and Shape:SolidMolecular weight:447.86Galidesivir
CAS:Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.Formula:C11H15N5O3Purity:96.73% - 99.13%Color and Shape:SolidMolecular weight:265.27RET-IN-10
CAS:RET-IN-10: Potent RET inhibitor, may treat congenital megacolon and tumors (Patent WO2021135938A1, compound 18).Formula:C29H28N8OSColor and Shape:SolidMolecular weight:536.65JAK3-IN-11
CAS:JAK3-IN-11: potent oral JAK3 inhibitor (IC50=1.7 nM), noncytotoxic, >588-fold selectivity, blocks T-cell growth; useful in autoimmune research.Formula:C23H23N5O2Color and Shape:SolidMolecular weight:401.46Gepotidacin hydrochloride
CAS:Gepotidacin (GSK-2140944) is a potent DNA topoisomerase inhibitor, a novel antibacterial efficacious against various anaerobes.Formula:C24H29ClN6O3Color and Shape:SolidMolecular weight:484.98Anti-MRSA agent 2
CAS:Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.Formula:C18H10Br2N2OColor and Shape:SolidMolecular weight:430.09Antitumor agent-50
Antitumor agent-50 (compound 1a) is a thiazolidinone.Formula:C17H14FNO3SColor and Shape:SolidMolecular weight:331.36Nenocorilant
CAS:Nenocorilant (Relacorilant) is an orally active glucocorticoid receptor (GR) antagonist (Ki: 0.15 nM). Nenocorilant can be used to study tumours.Formula:C26H21F4N7O3SColor and Shape:SolidMolecular weight:587.55G108
CAS:G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.Formula:C16H14Cl2N4O2Purity:99.13% - 99.75%Color and Shape:SolidMolecular weight:365.21Factor B-IN-4
CAS:Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.Formula:C27H32N2O4Color and Shape:SolidMolecular weight:448.55DNA gyrase B-IN-1
DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.Formula:C23H18ClF3N6O4SColor and Shape:SolidMolecular weight:566.94sEH inhibitor-2
SEH inhibitor-2 is an orally active sEH blocker (IC50=0.9 nM) with predicted 71.2-88.4% absorption, potentially aiding cardiovascular health.Formula:C23H18N4O3Color and Shape:SolidMolecular weight:398.41
