Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,832 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,611 products)
- Cytoskeletal Signaling(1,564 products)
- DNA Damage/DNA Repair(2,873 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,851 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,690 products)
- Stem Cell and Derivatives(734 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,725 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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FXIa-IN-9
CAS:FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.Formula:C23H18Cl2F3N9O2Color and Shape:SolidMolecular weight:580.35PptT-IN-3
PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.Formula:C16H27N5O3SColor and Shape:SolidMolecular weight:369.48PptT-IN-1
PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.Formula:C18H29N5O2Color and Shape:SolidMolecular weight:347.46XP5
XP5 is an oral HDAC6 inhibitor, potent against cancer cells, including YCC3/7 (IC50=31 nM to 2.31 μM).Formula:C19H25N3O5SColor and Shape:SolidMolecular weight:407.48Aurora inhibitor 1
CAS:Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).Formula:C23H25N9SPurity:98%Color and Shape:SolidMolecular weight:459.57KRas G12C inhibitor 2
CAS:KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.Formula:C32H37N7O3Purity:98%Color and Shape:SolidMolecular weight:567.681,9-Dideoxyforskolin
CAS:The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.5LY309887
CAS:LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.Formula:C19H23N5O6SColor and Shape:SolidMolecular weight:449.48Furaprevir
CAS:Furaprevir is an HCV NS3/4A InhibitorFormula:C47H56N6O10SColor and Shape:SolidMolecular weight:897.05GSK8814
CAS:GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan).Formula:C28H35F2N5O3Purity:98%Color and Shape:SolidMolecular weight:527.61O-GlcNAcase-IN-1
O-GlcNAcase-IN-1 is a potent and novel inhibitor of O-GlcNAcase(OGA) with an IC 50 value of 46 nM.Formula:C15H22N6Color and Shape:SolidMolecular weight:286.38SOS1-IN-10
SOS1-IN-10 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 13 nM).Formula:C22H19F5N4OColor and Shape:SolidMolecular weight:450.4HSV-TK substrate
CAS:HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.Formula:C11H15N5O4Purity:98%Color and Shape:SolidMolecular weight:281.27(S)-Seco-Duocarmycin SA
CAS:(S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can be used to synthesize ADC compounds.Formula:C25H24ClN3O7Purity:98%Color and Shape:SolidMolecular weight:513.93Elongation factor P-IN-1
EFP-IN-1: potent β-lysine derivative, inhibits EFP, slows E. coli growth.Formula:C14H31N3O2Color and Shape:SolidMolecular weight:273.41A 76889
CAS:A 76889 is an inhibitor of HIV-1 protease.Formula:C44H58N8O6Purity:98%Color and Shape:SolidMolecular weight:794.98GSK579289A
CAS:GSK579289A is an inhibitor of benzimidazole thiophene.Formula:C26H27ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:511.04Antitumor agent-78
Antitumor agent-78 blocks GPx-4, raises COX2, triggers apoptosis, halts EMT, and stifles cancer cell growth and migration.Color and Shape:SoildBAY 38-7271
CAS:BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).Formula:C20H21F3O5SPurity:98%Color and Shape:SolidMolecular weight:430.44Lp-PLA2-IN-6
CAS:Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.Formula:C25H21F5N4O3Color and Shape:SolidMolecular weight:520.45EGFR-IN-58
EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.Formula:C31H30FN7OColor and Shape:SolidMolecular weight:535.61Cilengitide hydrochloride
CAS:Cilengitide hydrochloride is a salt that may combat cancer by blocking specific integrins, disrupting cell interactions and angiogenesis.Formula:C27H41ClN8O7Color and Shape:SolidMolecular weight:625.12Chitin synthase inhibitor 11
Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.Formula:C24H24N4O8Color and Shape:SolidMolecular weight:496.47Mf 268
CAS:Mf 268 is a pseudo-reversible carbamate-type inhibitor which interacts with the catalytic and regulatory anionic site of the enzyme.Formula:C28H46N4O3Color and Shape:SolidMolecular weight:486.69ZL-Pin13
CAS:ZL-Pin13: potent Pin1 inhibitor (IC50: 67 nM), halts MDA-MB-231 cell growth, reduces Pin1 substrates.Formula:C24H23ClN2O3SColor and Shape:SoildMolecular weight:454.97P-gp/BCRP-IN-1
CAS:P-gp/BCRP-IN-1, safe and oral, inhibits P-gp/BCRP transporters, enhancing Paclitaxel bioavailability.Formula:C27H25ClN4O3Color and Shape:SolidMolecular weight:488.97BI-44370
CAS:BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.Formula:C35H47N5O6Color and Shape:SolidMolecular weight:633.78Enpp-1-IN-12
ENPP1-IN-12 is a potent, oral ENPP1 inhibitor with a Ki of 41 nM and anti-tumor properties.Formula:C17H19N5O3SColor and Shape:SolidMolecular weight:373.43MMAF sodium
CAS:MMAF sodium, a potent tubulin inhibitor in ADCs like Vorsetuzumab mafodotin and SGN-CD19A, acts as an antitumor agent.Formula:C39H64N5NaO8Purity:98%Color and Shape:SolidMolecular weight:753.94J-113397
CAS:J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).Formula:C24H37N3O2Purity:98%Color and Shape:SolidMolecular weight:399.57SF0166
CAS:SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.Formula:C23H27F2N5O4Color and Shape:SolidMolecular weight:475.49CYP2C19-IN-1
CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.Formula:C26H26N2O6SColor and Shape:SolidMolecular weight:494.56Anticancer agent 12
Anticancer agent 12 shows cytotoxic activity in malignant cells with no hepatotoxicity.Formula:C16H17BrN4O2SColor and Shape:SolidMolecular weight:409.3METTL3-IN-2
CAS:METTL3-IN-2, a potent METTL3 inhibitor, exhibits an IC50 value of 6.1 nM, effectively impairing the proliferation of Caov3 cancer cells.Formula:C25H26N8OColor and Shape:SolidMolecular weight:454.53Diarylalkane derivative 1
CAS:Diarylalkane derivative 1 is used for the research of pancreatitis.Formula:C34H51NO4Purity:98%Color and Shape:SolidMolecular weight:537.77VEGFR2-IN-1
CAS:VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.Formula:C22H18N6SPurity:98.15%Color and Shape:SolidMolecular weight:398.48Pomaglumetad methionil
CAS:Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.Formula:C12H20N2O8S2Purity:98%Color and Shape:SolidMolecular weight:384.43Daeatal
CAS:Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.Formula:C56H93N19O10Purity:98%Color and Shape:SolidMolecular weight:1192.46CXCR2 antagonist 5
CXCR2 antagonist 5 (compound 25) binds strongly (IC50=0.013μM) and mobilizes calcium (IC50=0.1μM).
Formula:C15H14F2N4O2SColor and Shape:SolidMolecular weight:352.36Mu opioid receptor antagonist 2
Compound 25: potent, selective MOR antagonist, crosses blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM), for OUD research.Formula:C25H28N2O4SColor and Shape:SolidMolecular weight:452.57Anti-inflammatory agent 23
Anti-inflammatory agent 23 blocks LPS-induced NO (IC50: 0.449 μM) and binds p65 well.Formula:C34H49NO6Color and Shape:SolidMolecular weight:567.76Metocurine chloride
CAS:Metocurine: a muscle relaxant, not for kidney failure patients as it's kidney-excreted.Formula:C40H48Cl2N2O6Color and Shape:SolidMolecular weight:723.72MRS2279
CAS:Selective, high affinity competitive antagonist of the P2Y1 receptorFormula:C13H18ClN5O8P2Purity:98%Color and Shape:SolidMolecular weight:469.71Onfasprodil
CAS:Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)Formula:C20H23FN2O3Color and Shape:SolidMolecular weight:358.41Dopamine D3 receptor antagonist-1
Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeuticFormula:C31H35Cl2N3O3Color and Shape:SolidMolecular weight:568.53ERK2 IN-1
CAS:ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.Formula:C36H34FN7O2SPurity:98%Color and Shape:SolidMolecular weight:647.76IL-17 modulator 5
CAS:IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM .Formula:C28H23F6N9O2Color and Shape:SolidMolecular weight:631.53Steroid sulfatase/17β-HSD1-IN-4
Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a potent dual inhibitor of steroid sulfatase ( STS ) and 17β-hydroxysteroid dehydrogenase type 1 ( 17β HSD1 ).Formula:C18H17N3O4S2Color and Shape:SolidMolecular weight:403.48BMS-986120
CAS:BMS-986120: Oral, reversible PAR4 antagonist. IC50: 9.5 nM (human), 2.1 nM (monkey). Potent, selective antiplatelet.Formula:C23H23N5O5S2Color and Shape:SolidMolecular weight:513.59PKCiota-IN-1
CAS:PKCiota-IN-1: Strong PKC-ι inhibitor (IC50=2.7 nM); also blocks PKC-α/ε (IC50s=45/450 nM).Formula:C25H22FN5OColor and Shape:SolidMolecular weight:427.47
