Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,852 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,430 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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Cap-dependent endonuclease-IN-17
CAS:CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.Formula:C24H20F2N3O7PSColor and Shape:SolidMolecular weight:563.47IAB15
CAS:IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Formula:C15H14F3NO2Color and Shape:SolidMolecular weight:297.27Neuraminidase-IN-11
Neuraminidase-IN-11 (15e) inhibits H1N1 (IC50: 4.7nM), H5N1 (8.46nM), H5N8 viruses (1.5nM) selectively & potently.
Color and Shape:SolidMetRS-IN-1
CAS:MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Formula:C15H13N3O4SColor and Shape:SolidMolecular weight:331.35RET-IN-11
RET-IN-11 selectively inhibits RET (IC50: 6.20 nM), promotes apoptosis, and hinders cell proliferation and migration.Formula:C27H30FN9OColor and Shape:SolidMolecular weight:515.59AD012
AD012, a dual cACE/NEP inhibitor, leverages lenopril-tryptophan for potential anti-hypertensive and cardioprotective benefits.Formula:C25H32N2O6Color and Shape:SolidMolecular weight:456.53HDAC-IN-27
HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3).Formula:C20H22N4O2Color and Shape:SolidMolecular weight:350.41EGFR/HER2-IN-6
EGFR/HER2-IN-6 is a dual inhibitor of EGFR, HER2, and DHFR with IC50s: 0.122, 0.078, and 0.585 μM, showing anticancer potential and selectivity.Formula:C18H21N5O3SColor and Shape:SolidMolecular weight:387.46L 156903
CAS:L 156903 is a bioactive chemical. It also inhibits the binding of neurotensin to brain tissue.Formula:C35H41N7O5SColor and Shape:SolidMolecular weight:671.81PI3Kα-IN-8
PI3Kα-IN-8 is a selective inhibitor of PI3Kα (IC50: 0.012 μM).Formula:C26H27BrN4O2Color and Shape:SolidMolecular weight:507.42Revamilast
CAS:Revamilast, also known as GRC4039, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritisFormula:C18H9Cl2F2N3O4Color and Shape:SolidMolecular weight:440.18ONO-AE1-259 lysine
CAS:ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)Formula:C28H49ClN2O6Color and Shape:SolidMolecular weight:545.15ONO-5334
CAS:ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).Formula:C21H34N4O4SPurity:98.22% - 99.60%Color and Shape:SolidMolecular weight:438.58HBV-IN-11
CAS:HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).Formula:C21H24ClNO6Color and Shape:SolidMolecular weight:421.87SLC4101431
SLC4101431 is a potent SphK2 inhibitor with Ki value of 90 nM.Formula:C29H28ClN7OSColor and Shape:SolidMolecular weight:558.1URAT1 inhibitor 3
URAT1 inhibitor 3: potent oral URAT1 blocker, IC50=0.8 nM, for gout/hyperuricemia study.Formula:C14H8Cl2N2O2Color and Shape:SolidMolecular weight:307.13AZD-3199 dihydrobromide
CAS:AZD-3199 dihydrobromide is a β2 adrenergic receptor agonist potentially for the treatment of asthma and chronic obstructive.Formula:C32H44Br2N4O4SColor and Shape:SolidMolecular weight:740.59ACT-281959
CAS:ACT-281959, a prodrug of ACT-246475, is a potent P2Y12 antagonist, better than Clopidogrel, effective orally, and in human trials.Formula:C38H55N6O14PColor and Shape:SolidMolecular weight:850.85Equisetin
CAS:Equisetin: a QSI from Fusarium equiseti, curbs P. aeruginosa virulence, fights Gram-positive bacteria & HIV-1 integrase; not antibacterial to Gram-negative.Formula:C22H31NO4Purity:98%Color and Shape:SolidMolecular weight:373.49RMS-07
CAS:RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.Formula:C35H40N8O2Color and Shape:SolidMolecular weight:604.74MA242
CAS:MA242 is a nuclear factor of activated T cells 1 (NFAT1) for Pancreatic Cancer Therapy and dual inhibitor of murine double minute 2 (MDM2).Formula:C26H21ClF3N3O5SPurity:98%Color and Shape:SolidMolecular weight:579.98Minnelide
CAS:Minnelide is a prodrug of triptolide,and shows potent antitumor activity in a number of tumor types.Formula:C21H25Na2O10PPurity:98.49% - 99.59%Color and Shape:SolidMolecular weight:514.37JAK3-IN-13
JAK3-IN-13: Oral JAK3 inhibitor, selective & potent. Acts on NK1, JNK2, JNK3, Tyk2. Anti-tumor. IC50: JNK3, 8 nM; Tyk2, 365 nM; JNK2, 2039 nM; NK1, 4728 nM.Formula:C25H33ClN6O5Color and Shape:SolidMolecular weight:533.02GNE684
CAS:GNE684 inhibits RIP1; Ki app: 21 nM (human), 189 nM (mouse), 691 nM (rat).Formula:C23H24N6O3Purity:98%Color and Shape:SolidMolecular weight:432.48Flusoxolol
CAS:Flusoxolol is a beta-adrenoceptor partial agonist.Formula:C22H30FNO4Color and Shape:SolidMolecular weight:391.48DC1SMe
CAS:DC1, a CC-1065-like ADC cytotoxin, is used in cancer-targeting antibody-drug conjugates. DC1Sme, a derivative, has IC50s: 22-250 pm in various cancer cells.Formula:C35H30ClN5O4S2Purity:98%Color and Shape:SolidMolecular weight:684.23(S)-3-Hydroxy Midostaurin
CAS:(S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).Formula:C35H30N4O5Purity:98%Color and Shape:SolidMolecular weight:586.64Dot1L-IN-1
CAS:The Ki value of DOT1L-in-1 is 2pm.It is a highly effective, selective and novel Dot1L inhibitor.Formula:C32H36ClN9O2SPurity:98%Color and Shape:SolidMolecular weight:646.21GSK699
CAS:GSK699 is a potent, cell penetrant PCAF/GCN5 PROTAC.
Formula:C45H51BrN8O7Color and Shape:SolidMolecular weight:895.84Antifungal agent 40
Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.Formula:C22H20Cl2N4SeColor and Shape:SolidMolecular weight:490.29Tubulin polymerization-IN-35
Tubulin-IN-35 inhibits oxazolylisoindole microtubule formation, targeting VL51 marginal zone lymphoma.Formula:C31H35N3O5Color and Shape:SolidMolecular weight:529.63Topoisomerase I/II inhibitor 4
Topoisomerase I/II inhibitor 4 halts cell growth and spread, induces apoptosis, and is used in liver cancer research.Formula:C27H21N5O6Color and Shape:SolidMolecular weight:511.49MC4355
MC4355 is a dual inhibitor of EZH2 and histone deacetylase (HDAC).Formula:C30H36N4O5Color and Shape:SolidMolecular weight:532.63PDHK-IN-5
PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.Formula:C30H31N5O2Color and Shape:SolidMolecular weight:493.6MDL-100240
CAS:MDL-100240 inhibits ACE/neprilysin, effective against hypertension-induced heart/vascular changes.Formula:C26H28N2O5SPurity:98%Color and Shape:SolidMolecular weight:480.58SC13
CAS:SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.Formula:C26H30N2O5Color and Shape:SolidMolecular weight:450.53Spliceostatin A
CAS:Spliceostatin A is an anticancer agent and splicing inhibitor that induces apoptosis by inducing cell cycle arrest in the G1 and G2/M phases.Formula:C28H43NO8Purity:94.66%Color and Shape:SolidMolecular weight:521.643BRD2879
CAS:BRD2879 is a potent and cell-active inhibitor of IDH1-R132H (IC50 = 50 nM).Formula:C30H38FN3O5SPurity:98%Color and Shape:SolidMolecular weight:571.70D18
CAS:D18: Dual agonist for TLR7/8, boosts PD-L1, aids tumor sensitivity to PD-1/PD-L1 inhibitors, and is a cytotoxin for ADC HE-S2.Formula:C21H28N6Color and Shape:SolidMolecular weight:364.49Ascofuranone
CAS:Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODHFormula:C23H29ClO5Color and Shape:SolidMolecular weight:420.93Ribocil-C R enantiomer
Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.Formula:C21H21N7OSPurity:98%Color and Shape:SolidMolecular weight:419.5hCAIX/XII-IN-1
hCAIX/XII-IN-1: potent CAIX inhibitor (KI=0.48μM), CAXII (KI=0.83μM), antiproliferative, induces apoptosis in MCF-7 cells.Formula:C19H11NO5S2Color and Shape:SolidMolecular weight:397.42LY 190388
CAS:LY 190388 is a penicillamine-containing enkephalin analog used as an mu receptor agonist with analgesia activity.Formula:C30H41N5O7SPurity:98%Color and Shape:SolidMolecular weight:615.74Rodatristat
CAS:Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).Formula:C27H27ClF3N5O3Purity:98%Color and Shape:SolidMolecular weight:561.98Cathepsin K inhibitor 2
CAS:Cathepsin K inhibitor 2 targets CTSK gene, may treat osteoporosis and osteoarthritis, detailed in patent WO2021147882A1.Formula:C30H33F4N5O3Color and Shape:SolidMolecular weight:587.61EP4 receptor antagonist 2
CAS:EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor (IC50: 7.8 nM) and has antitumour effects.Formula:C27H29N3O5Color and Shape:SolidMolecular weight:475.54CDK5-IN-2
CAS:CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor that acts on CDK5/p25 (IC50: 0.2 nM) and CDK2/CycA (IC50: 23 nM).Formula:C29H28FN5OColor and Shape:SolidMolecular weight:481.56BW A868C
CAS:BW A868C is a potent, selective PGD2 antagonist and a BW245C analogue, inert to other prostaglandin receptors.Formula:C25H37N3O5Color and Shape:SolidMolecular weight:459.58GNTI dihydrochloride
CAS:κ opioid receptor antagonistFormula:C27H30ClN5O3Purity:98%Color and Shape:SolidMolecular weight:508.01G247
G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.Formula:C24H19Cl2FO3Color and Shape:SolidMolecular weight:445.31
