Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,852 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,430 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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TT15
CAS:TT15 is an agonist of the GLP-1R.Formula:C51H44Cl2N4O6Color and Shape:SolidMolecular weight:879.82Antibacterial agent 88
Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.Formula:C31H44N2O6SColor and Shape:SolidMolecular weight:572.76Desacetylravidomycin
CAS:Desacetylravidomycin is a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp. WK-6326.Formula:C29H31NO8Color and Shape:SolidMolecular weight:521.56Tubulin inhibitor 15
Tubulin inhibitor 15 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 15 exhibits cytotoxicity in HepG2 cells [1].Formula:C16H12FNO2Color and Shape:SolidMolecular weight:269.27KRAS G12C inhibitor 50
CAS:KRAS G12C inhibitor 50 is a KRAS G12C inhibitor (IC50: 46.7 nM).Formula:C31H34N8O2Color and Shape:SolidMolecular weight:550.65GLS-1-IN-1
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.Formula:C26H25FN4OSColor and Shape:SolidMolecular weight:460.57TP-6076
CAS:TP-6076 is a fluorocycline antibiotic, inhibiting bacterial protein synthesis, exhibiting great antimicrobial activity against carbapenem-resistant A.Formula:C28H32F3N3O7Color and Shape:SolidMolecular weight:579.56BTK-IN-16
CAS:BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to study various autoimmune diseases and cancers caused by BTK.Formula:C15H14N4O2Purity:99.04%Color and Shape:SoildMolecular weight:282.3MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Formula:C22H24N4O3Color and Shape:SolidMolecular weight:392.45GDC-6036-NH
CAS:GDC-6036-NH is a precursor of compound 17a /b, which is a RAS inhibitor that can be used in cancer research.Formula:C26H30ClF4N7OPurity:99.84%Color and Shape:SolidMolecular weight:568.01DN-F01
DN-F01 exhibits a potent calcium-dependent inhibitory effect on cardiac myofibrillar ATPase activity, with an IC50 of 11 ± 4 nmol/L.Formula:C22H16N2O2Color and Shape:SolidMolecular weight:340.37Cyclic-di-GMP sodium
c-di-GMP sodium: STING activator, regulates bacteria biofilm, motility, virulence.Formula:C20H24N10NaO14P2Color and Shape:SolidMolecular weight:713.08464RORγt/DHODH-IN-3
RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 hasFormula:C24H26ClF6N3O3SColor and Shape:SolidMolecular weight:585.99H3R antagonist 2
Compound 23: H3R antagonist with 170 nM Ki; inhibits AChE, BChE, hMAO B; IC50s: 180, 880, 775 nM; anti-pain, memory boost; crosses BBB. [1]Formula:C24H29NO3Color and Shape:SolidMolecular weight:379.49BRD4 D1-IN-1
BRD4 D1-IN-1 selectively inhibits BRD4 D1 (IC50 <0.092 μM, Kd 18 nM) with >500-fold specificity versus D2.Formula:C32H37F3N6OColor and Shape:SolidMolecular weight:578.67ZD6021
CAS:ZD6021 is an antagonist of neurokinin 1 receptor.Formula:C35H35Cl2N3O2SPurity:98%Color and Shape:SolidMolecular weight:632.64PI3K-IN-26
CAS:PI3K-IN-26 is an effective PI3K inhibitor. PI3K-IN-26 inhibits the proliferation of SU-DHL-6 cells, IC50= 36 nM.Formula:C21H18N6OSColor and Shape:SolidMolecular weight:402.47PDHK-IN-3
PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].Formula:C17H16N2O2Color and Shape:SolidMolecular weight:280.32Musettamycin
CAS:Musettamycin triggers erythroid differentiation in blood cells, acts like anthracycline antibiotics, but only inhibits gram-positive bacteria.Formula:C36H45NO14Color and Shape:SolidMolecular weight:715.74AAK1-IN-2 TFA
AAK1-IN-2 TFA (compound (S)-31) is a selective and potent AAK1 inhibitor (IC50: 5.8 nM) that can cross the blood-brain barrier.Formula:C24H22F6N4O4Color and Shape:SolidMolecular weight:544.45Peridinin
CAS:Peridinin is an exceptionally potent and membrane-embedded inhibitor of bilayer lipid peroxidation.Formula:C39H50O7Color and Shape:SolidMolecular weight:630.81TLR7/8 antagonist 2
TLR7/8 antagonist 2: potent, orally active, IC50: 4.9 nM (TLR7), 0.6 nM (TLR8); potential for lupus therapy research.Formula:C22H26FN5Color and Shape:SolidMolecular weight:379.47Butaprost
CAS:Butaprost: EP2 receptor agonist, EC50=33 nM, Ki=2.4 μM (murine), reduces fibrosis via TGF-β/Smad2.Formula:C24H40O5Purity:98%Color and Shape:SolidMolecular weight:408.57Cap-dependent endonuclease-IN-25
CAS:Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48Calpain Inhibitor-2
CAS:Calpain Inhibitor-2: Lipophilic, moderates growth of A-375, B-16F1, PC-3 cancers, and hinders 80% DU-145 cell invasion.Formula:C26H33N3O5SColor and Shape:SolidMolecular weight:499.62Cap-dependent endonuclease-IN-17
CAS:CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.Formula:C24H20F2N3O7PSColor and Shape:SolidMolecular weight:563.47AChE/BuChE-IN-3
CAS:AChE/BuChE-IN-3 inhibits AChE (IC50: 0.65 μM), BuChE (IC50: 5.77 μM), crosses BBB, and hinders Aβ1-42 aggregation for Alzheimer's research.Formula:C30H30F3N3O6Color and Shape:SolidMolecular weight:585.57Aristoforin
CAS:Aristoforin is a SIRT1 and SIRT2 inhibitor that induces cell cycle arrest, shows potent antitumor effects, and inhibits lymphangiogenesis in vivo.Formula:C37H54O6Color and Shape:SolidMolecular weight:594.82HDAC/Top-IN-1
CAS:HDAC/Top-IN-1, an oral HDAC/Top inhibitor, targets HDAC1-3,6,8 with low IC50s; blocks S-phase & induces apoptosis in HEL cells.Formula:C29H25FN4O4Color and Shape:SolidMolecular weight:512.53U 75875
CAS:U 75875 is a protease inhibitor.Formula:C45H61N7O7Color and Shape:SolidMolecular weight:812.01β-N-Acetyl-D-hexosaminidase-IN-1
β-N-Acetyl-D-hexosaminidase-IN-1 is a newly discovered chemical compound that acts as an inhibitor for β-N-acetyl-D-hexosaminidase.Formula:C18H13F2NO2SColor and Shape:SolidMolecular weight:345.36HBV-IN-31
CAS:HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.Formula:C23H18ClNO6Color and Shape:SolidMolecular weight:439.85Gallinamide A
CAS:Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.Formula:C31H52N4O7Color and Shape:SolidMolecular weight:592.77Xylarianaphthol-1
CAS:Xylarianaphthol-1 is an activator of p21 promoter in a p53-independent manner.Formula:C16H20BrFN2O2Color and Shape:SolidMolecular weight:371.24Tonantzitlolone
CAS:Tonantzitlolone activates TRPC1/4/5 channels, PKCα/θ, inhibits IRS1/PI3K/AKT, and triggers HSF1 to induce glucose dependence.Formula:C26H40O7Color and Shape:SolidMolecular weight:464.59MraY-IN-2
MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.Formula:C16H23N3O9Color and Shape:SolidMolecular weight:401.37RF9 hydrochloride
RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).Formula:C26H39ClN6O3Color and Shape:SolidMolecular weight:519.08HDAC-IN-47
HDAC-IN-47: Oral HDAC inhibitor (IC50: 19.75-302.73 nM for HDAC1-8), blocks G2/M, inhibits autophagy, triggers apoptosis, anti-cancer in vivo.Formula:C17H20BrN3O4Color and Shape:SolidMolecular weight:410.26Cap-dependent endonuclease-IN-14
CAS:Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).Formula:C30H23FN2O6SColor and Shape:SolidMolecular weight:558.58Chitin synthase inhibitor 11
Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.Formula:C24H24N4O8Color and Shape:SolidMolecular weight:496.47Chitinase-IN-5
Chitinase-IN-5 (8i) blocks OfChi-h (IC50: 0.051 μM), has insecticidal qualities, useful for eco-friendly pest control.Formula:C20H21ClFN7Color and Shape:SolidMolecular weight:413.88MtMetAP1-IN-1
MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.Formula:C15H10BrN5O2SColor and Shape:SolidMolecular weight:404.248(S),15(S)-DiHETE
CAS:8(S),15(S)-DiHETE, from 15(S)-HETE's oxidation by 15-LO, triggers eosinophil movement at 1.5 μM; it counteracts pain and LTB4 effects.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47nAChR antagonist 1
CAS:Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.Formula:C19H22N4O2Color and Shape:SolidMolecular weight:338.4CS-003 Free base
CAS:CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.Formula:C34H38Cl2N2O6SPurity:98%Color and Shape:SolidMolecular weight:673.65S1P1 agonist 4
CAS:S1P1 agonist 4 exhibits enhanced potency with an EC 50 value of less than 0.05 mg/kg and a predicted human half-life (t1/2) of approximately 5 days, indicatingFormula:C24H31NO3Color and Shape:SolidMolecular weight:381.51Anticancer agent 78
Anticancer agent 78: anti-aromatase (IC50=0.9 μM), cytotoxic, potential in breast cancer research.Formula:C19H14BrNO4Color and Shape:SolidMolecular weight:400.22DAD dichloride
DAD dichloride is a 3rd-gen photoelectric switch, blocks K+ channels, and helps in visual function research.Formula:C26H42Cl2N6OColor and Shape:SolidMolecular weight:525.56VU0463271 quarterhydrate
VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].Formula:C19H20N4O2S2Color and Shape:SolidMolecular weight:38716,16-Dimethyl prostaglandin E2
CAS:16,16-Dimethyl prostaglandin E2 regulates hematopoietic stem cells via EP2/EP4 and Wnt, taken orally.Formula:C22H36O5Purity:98%Color and Shape:SolidMolecular weight:380.52
