Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,852 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,430 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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Anticancer agent 35
Compound 10, a sulfonylurea, inhibits A549, A431, PACA2 cells with IC50s: 18.1, 4.0, 18.9 μg/mL.Formula:C15H13N3O3S3Color and Shape:SolidMolecular weight:379.48E6201
CAS:E6201, a dual kinase inhibitor, blocks MEK1/FLT3 and has anti-tumor/psoriasis effects with low IC50s: ERK2 (5.2 nM), JNK (91 nM), p38 MAPK (19 nM).Formula:C21H27NO6Color and Shape:SolidMolecular weight:389.44SDM25N hydrochloride
CAS:δ receptor antagonistFormula:C26H27ClN2O3Purity:98%Color and Shape:SolidMolecular weight:450.96Antifungal agent 40
Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.Formula:C22H20Cl2N4SeColor and Shape:SolidMolecular weight:490.29NBTIs-IN-5
CAS:NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.Formula:C24H25F3N4O2Color and Shape:SolidMolecular weight:458.48DBCO-Sulfo-Link-biotin
CAS:DBCO-Sulfo-Link-biotin is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].Formula:C31H35N5O7S2Purity:98%Color and Shape:SolidMolecular weight:653.77MK-7128
CAS:MK-7128 is a CB1 receptor inverse agonist.Formula:C29H25ClF2N4O2Color and Shape:SolidMolecular weight:534.98NVP-CFC218
CAS:NVP-CFC218 is a novel potent and selective p53-HDM2 inhibitor.Formula:C37H45ClN4O4Color and Shape:SolidMolecular weight:645.23(-)-Adenophorine
CAS:(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.Formula:C8H17NO4Color and Shape:SolidMolecular weight:191.22CBR Agonist-1
CBR Agonist-1 targets CB1R and CB2R with Ki of 0.18 μM and 1.22 μM, useful for studying cannabinoid-related diseases.Formula:C27H27FN4OColor and Shape:SolidMolecular weight:442.53AM Toxin II
CAS:AM Toxin II is a Cyclic tetradepsipeptide isolated from Alternaria mali.Formula:C22H29N3O5Color and Shape:SolidMolecular weight:415.49SJF 8240
CAS:c-MET degrader with foretinib linked to VHL ligand; reduces c-MET in 6h, hampers AKT, halts GTL16 cells (IC50=66.7nM), acts on exon-14-less c-MET.
Formula:C58H65F2N7O11SColor and Shape:SolidMolecular weight:1106.25T01-1
CAS:T01-1, a derivative of camptothecin, is an anticancer agent demonstrating significant anti-proliferative activity.Formula:C26H29N3O6SColor and Shape:SolidMolecular weight:511.59MB-7133
CAS:MB-7133 is an inhibitor of DNA synthesis.Formula:C17H21N4O8PPurity:98%Color and Shape:SolidMolecular weight:440.34TP-6076
CAS:TP-6076 is a fluorocycline antibiotic, inhibiting bacterial protein synthesis, exhibiting great antimicrobial activity against carbapenem-resistant A.Formula:C28H32F3N3O7Color and Shape:SolidMolecular weight:579.56CEP-2563
CAS:CEP-2563 is a prodrug of CEP-751. It also used as an antitumor agent, inhibiting protein kinases.Formula:C36H41ClN6O6Purity:98%Color and Shape:SolidMolecular weight:689.20NNC 55-0396
CAS:NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.Formula:C30H40Cl2FN3O2Purity:99.00%Color and Shape:SolidMolecular weight:564.56Ref: TM-T12238
1mg63.00€5mg119.00€10mg192.00€25mg335.00€50mg520.00€100mg745.00€1mL*10mM (DMSO)152.00€CS-003 Free base
CAS:CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.Formula:C34H38Cl2N2O6SPurity:98%Color and Shape:SolidMolecular weight:673.65MCTR3
CAS:MCTR3, derived from DHA via maresin 1 in macrophages, hastens tissue healing and reduces inflammation and eicosanoids post-E. coli infection in mice.Formula:C25H37NO5SColor and Shape:SolidMolecular weight:463.63SG3199
CAS:SG3199, a PBD dimer, binds DNA's minor groove, forms covalent cross-links, and is cytotoxic to various human cancer cells.Formula:C33H36N4O6Color and Shape:SolidMolecular weight:584.66Triphen diol
CAS:Triphen diol, a phenol diol, fights pancreatic cancer & cholangiocarcinoma, inducing apoptosis via caspase-dependent & -independent paths.Formula:C22H20O4Color and Shape:SolidMolecular weight:348.39Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Formula:C24H28FN5O8Color and Shape:SolidMolecular weight:533.515(S),6(S)-DiHETE
CAS:5(S),6(S)-DiHETE: a 5,6-dihydroxy acid from LTA4 hydrolysis, lacks leukotriene activity.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47GDC-6036-NH
CAS:GDC-6036-NH is a precursor of compound 17a /b, which is a RAS inhibitor that can be used in cancer research.Formula:C26H30ClF4N7OPurity:99.84%Color and Shape:SolidMolecular weight:568.01Tabimorelin hemifumarate
CAS:orally active ghrelin receptor (GHS-R1a) agonistFormula:C32H40N403C4H404Purity:98%Color and Shape:SolidMolecular weight:586.72Balanol
CAS:Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.Formula:C28H26N2O10Color and Shape:SolidMolecular weight:550.51MEN-10354
CAS:MEN-10354 is a less potent and less selective NK-2 tachykinin receptor antagonist compared to the linear analog, R 396.Formula:C37H46N8O9Color and Shape:SolidMolecular weight:746.813-IN-PP1
CAS:3-IN-PP1: PKD inhibitor (IC50: 94-108 nM for PKD1/2/3), broad anticancer agent for research.Formula:C17H18N6Color and Shape:SolidMolecular weight:306.36NK-1 Antagonist 1
CAS:NK-1 Antagonist 1 is a NK-1 receptor antagonist.Formula:C25H23F6N5O2Purity:98%Color and Shape:SolidMolecular weight:539.47sEH inhibitor-1
TCPU (sEH inhibitor-1) is a potent oral human sEH blocker with IC50s of 0.4 nM (human) and 5.3 nM (mouse).
Color and Shape:SolidAM-3189
CAS:AM-3189: potent, selective GPR40 agonist with low CNS penetration, good pharmacokinetics, and efficacy mirroring AMG 837.Formula:C27H25ClN2O3Color and Shape:SolidMolecular weight:460.95GLS-1-IN-1
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.Formula:C26H25FN4OSColor and Shape:SolidMolecular weight:460.57PS-519
CAS:PS-519 is a human tissue plasminogen activator and proteasome inhibitor.Formula:C12H19NO4Color and Shape:SolidMolecular weight:241.28CHK1 inhibitor
CAS:CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.Formula:C17H21BrN4OPurity:98%Color and Shape:SolidMolecular weight:377.28Aurora inhibitor 1
CAS:Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).Formula:C23H25N9SPurity:98%Color and Shape:SolidMolecular weight:459.57KRAS G12D inhibitor 11
CAS:KRAS G12D inhibitor 11 targets KRAS G12D in cancer research (patent WO2021108683A1, compound 52).Formula:C29H38BN5O3Color and Shape:SolidMolecular weight:515.45NLRP3-IN-4
NLRP3-IN-4 is an effective, oral NLRP3 inflammasome inhibitor with potent anti-inflammatory effects on colitis.Formula:C22H22N2O5Color and Shape:SolidMolecular weight:394.42HBV-IN-12
CAS:HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)Formula:C23H27NO8Color and Shape:SolidMolecular weight:445.46Antitumor agent-76
CAS:Antitumor agent-76 is a water-soluble, orally active, rapid-release prodrug of Triptolide that exhibits anticancer effects.Formula:C28H36ClNO10Color and Shape:SolidMolecular weight:582.04AZ12971554
AZ12971554: Human thrombin inhibitor, Ki=0.3nM; APTT IC50=0.68µM; ECT IC50=0.16µM.Formula:C20H17ClFN7O3Color and Shape:SolidMolecular weight:457.85EB-0176
EB-0176: A valerian derivative; broad-spectrum antiviral; potent ER α-glucosidase I/II inhibitor; IC50s: 0.6439/0.0011 μM.Formula:C23H33N5O7Color and Shape:SolidMolecular weight:491.54A-9758
CAS:A-9758: RORγt selective inverse agonist, IC50 5nM, inhibits IL-17A, Th17, and treats psoriasis.Formula:C25H23Cl2F3N2O3Purity:98%Color and Shape:SolidMolecular weight:527.36Amicoumacin A
CAS:Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.Formula:C20H29N3O7Purity:98%Color and Shape:SolidMolecular weight:423.46AVE 0991
CAS:AVE 0991 is a nonpeptide analog of angiotensin-(1-7), a Mas agonist with inhibitory effects on [125I]-Ang-(1-7) and on neuroinflammation in Alzheimer's disease.Formula:C29H32N4O5S2Purity:99.73%Color and Shape:SolidMolecular weight:580.72GS-9822
CAS:GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.Formula:C36H39ClN4O4SColor and Shape:SolidMolecular weight:659.24Dyrk1A/α-synuclein-IN-1
Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual inhibitor of Dyrk1A (IC50: 177 nM) and α-synuclein aggregation (IC50: 10.5 μM).Formula:C20H21N5O3SColor and Shape:SolidMolecular weight:411.48PF1070A
CAS:PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothioneinFormula:C31H44N4O6Color and Shape:SolidMolecular weight:568.7BI-685509
CAS:BI-685509: potent, oral sGC activator, boosts cGMP, enhances NO pathways, for CKD/DKD research.Formula:C34H38N4O5Color and Shape:SolidMolecular weight:582.69Homopteroic Acid
CAS:Homopteroic Acid, a precursor to Homofolic Acid, inhibits L1210 mouse leukemia growth by targeting folate uptake.Formula:C15H14N6O3Color and Shape:SolidMolecular weight:326.31FAK-IN-2
FAK-IN-2: potent oral FAK inhibitor, IC50 35 nM, reduces tumor growth, migration, and induces cell death.Formula:C28H31ClN8O3Color and Shape:SolidMolecular weight:563.05
