Inhibitors

Mouse IgG3 kappa Isotype Control is a monoclonal antibody serving as an isotype control specifically for mouse IgG3κ antibodies.

PROTAC BRD4 Degrader-16 is a potent degrader of BRD4, exhibiting IC50 values of 34.58 nM for BRD4 (BD1) and 40.23 nM for BRD4 (BD2).

Spiratisanin A is a natural product from Spiraea japonica.

MCAAD-3, a near-infrared Aβ imaging probe, exhibits blood-brain barrier permeability and strong affinity for Aβ polymers (Ki >106 nM).

IDO1-IN-20 is an enzyme that catalyzes the oxidative metabolism of tryptophan. It can immunosuppress tumors in the tumor microenvironment.

KHS 101 hydrochloride is a neuronal differentiation inducer

m-PEG11-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

C.I. Pigment Yellow 14 is a yellow dye.

PROTAC MDM2 Degrader-2: A potent MDM2-targeting compound with PROTAC tech for E3 ligase-mediated degradation.

Darobactin is an antibiotic effective against critical Gram-negative pathogens, demonstrating activity both in vitro and in animal infection models [1].

GEM-5, a gemcitabine conjugate with HIF-1α inhibitor YC-1 (IC50=30 nM), down-regulates HIF-1α, up-regulates p53, and induces A2780 cell apoptosis.

Trk-IN-6 shows excellent in vitro potency on a panel of TRK mutants ( IC 50 = 0.2-0.7 nM).

1-Hydroxybisabola-2,10-dien-4-one is a natural product for research related to life sciences. The catalog number is TN5398 and the CAS number is 124898-71-1.

Cap-dependent endonuclease-IN-12 (EXP-35) is a potent inhibitor with low toxicity, active against H1N1.

Compound 32a: PROTAC BRD4 Degrader-6, IC50 = 2.7 nM, degrades BRD4, halts BxPC3 pancreatic cancer cell growth, induces apoptosis for research.

PROTAC eEF2K degrader-1 (11l) targets eEF2K, induces apoptosis in MDA-MB-231 cells, and degrades eEF2K.

PROTAC MDM2 Degrader-3 uses PROTAC tech to efficiently break down MDM2 with a potent inhibitor and E3 ligase ligand.

HJM-561 is a potent and selective EGFR PROTAC with oral bioavailability, capable of overcoming osimertinib-resistant EGFR triple mutations and demonstrating

NT 2 Toxin is a useful organic compound for research related to life sciences. The catalog number is T124258 and the CAS number is 76348-84-0.

Elamipretide TFA (RX-31 TFA) is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide[1].

PROTAC BTK Degrader-3 is a potent degrader of Bruton's tyrosine kinase (BTK), exhibiting a DC50 (median degradation concentration) of 10.9 nM in Mino cells.

Lupinine hydrochloride is a bioactive chemical.

1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.

CAY10735: Anticancer agent; inhibits growth/migration in various cancer cells; reduces tumor in mouse models. IC50=0.674-11.56μM.

Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.

Yimitasvir, an oral NS5A inhibitor, treats chronic hepatitis C. Used for research.

Questiomycin A derivatives 20 is a Questiomycin A derivative.

α-conotoxin GI, a conopeptide isolated from the venom of the cone snail Conus geographus, is a competitive antagonist of the muscle-type nicotinic acetylcholine

Oroxin A, a partial PPARγ agonist, activates PPARγ, inhibits α-glucosidase, and has antioxidant properties.

(5R)-Platyphyllone has a wide range of applications in life science related research.