Carbohydrates and glycoconjugates

<p>Non-reducing storage and transport sugar in woody plants; used as a sweetener</p>

<p>Substrate for glucoamylases; derived from pullulan using pullulanase</p>

<p>High mannose oligosaccharide found in urine of mannosidosis patients</p>

<p>Bulk sweetener; viscosity/bodying agent; humectant; cryoprotectant</p>

<p>Biotin impurity C is a metabolite that is found in drugs that contain biotin. It is an impurity standard for HPLC analysis, which can be used to identify and quantify the amount of biotin in a drug product. Biotin impurity C is also used as an analytical standard. This compound has been shown to have pharmacological properties, such as anti-inflammatory effects and immunomodulatory effects.</p>

<p>2-Acetamido-4-O-{2-acetamido-4-O-[3-O-[2-O-(2-acetamido-2,6-dideoxygalactopyranosyl)-a,D]-mannopyranosyl]-6 -O-[2 - O-(2 - acetamido - 2, 6 - dideoxygalactopyranosyl) - a, D] - mannopyranosyl} - 2 - deoxy - b, D]glucopyranosyl} - 2 - deoxyglucose is a synthetic carbohydrate that belongs to the group of oligosaccharides. It is a complex carbohydrate consisting of six glucose molecules linked by alpha (1→4) glycosidic bonds. The chemical name for this molecule is Custom synthesis and it has CAS No. 91471-04-8. This product can be modified through methylation, glycos</p>

<p>1,5-a-L-Arabinobiose is a sugar that is found in mammalian tissue and has been shown to have enzyme activities. It can be prepared by high performance liquid chromatography and titration calorimetry. 1,5-a-L-Arabinobiose has hydrogen bonding interactions with its neighbouring molecules and surface methodology. It also has structural analysis with hydrogen bonds and phenolic acids. 1,5-a-L-Arabinobiose is used as a probiotic bacteria growth factor in microalgal cultures.</p>

<p>2-Amino-2-deoxy-3-O-(b-D-glucopyranuronosyl)-D-galactopyranose monohydrate is a glycoside that is found in the testes. It has inhibitory properties on oligosaccharides and can be used to study the structure of glycoconjugates. 2-Amino-2-deoxy-3-O-(b-D-glucopyranuronosyl)-D-galactopyranose monohydrate has been shown to inhibit the enzyme hydrolase, which is involved in glycoprotein synthesis. 2ADOGP has also been shown to bind to human serum albumin, an abundant protein in human blood plasma that transports lipids, hormones, and other molecules throughout the body. This binding results in a decrease in the serum concentration of 2ADOGP after administration.</p>

<p>Intermediate degradation product of lyso-GM3</p>

<p>Mixed DP 25-50 Na galacturonans, (α-1,4 25-50 Na galacturonans) are derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis. They are used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s). In recent studies, it has been shown that long oligogalacturonides (degree of polymerization (DP) from 25–50), help to induce plant defense signaling resulting in enhanced defenses to necrotrophic pathogens.</p>

<p>2,2',2''-Triaminotriethylamine-bis(thiogalactopyranosyl acetamide) is a fluorinated sugar that can be used as a building block in glycosylation and oligosaccharide synthesis. It has been shown to be useful for the preparation of complex carbohydrates with desired properties such as high purity.</p>

<p>Oligosaccharide domain of monosialylated glycosphingolipid GM1 with an α1,2-fucosylated galactose at the nonreducing end. The moluecule is minimally expressed in healthy tissues but has high prevalence in some tumours such as small cell lung cancer (SCLC). Fucosyl-GM1 ganglioside is a potential tumour marker for SCLC and a potential antigen target for immunotherapy.</p>

<p>Trehalose is a naturally occurring disaccharide found in many organisms. Its role in nature is as versatile as its applications in the laboratory. Trehalose is synthesised by cells in response to stress and helps retaining the cellular integrity under tough conditions. An important function of trehalose is to stabilise protein structures and to prevent proteins from their degradation. Researchers use trehalose for instance as a carbon source in selective microbiological media, as desiccation protectant and for cryoprotection.</p>

<p>Oligogalactosyllactose is a polysaccharide made from galactose and glucose. Oligogalactosyllactose has been shown to have an inhibitory effect on the growth of Staphylococcus aureus strains. Oligogalactosyllactose also has anti-inflammatory properties, which may be due to its ability to bind to free fatty acids and reduce the production of pro-inflammatory cytokines. This dietary ingredient is found in inulin, which is a type of carbohydrate that can be found in some vegetables. Oligogalactosyllactose is composed of short chains of sugar molecules, making it easier for the body to absorb. It is also more readily metabolized by bacteria in the gut than other types of carbohydrates like celluloses or starches.</p>

<p>Please enquire for more information about 4-O-[(2-Azidoethoxyimino)-6-deoxy-β-D-galactopyranosyl]-2-deoxy-α-D-glucopyranose-2,1-oxazoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,5-α-L-Arabinotriose is a sugar that is found in the cell walls of plants. It is a trisaccharide composed of three L-arabinose units linked by α-(1→5) bonds. 1,5-α-L-Arabinotriose has been shown to be adsorbed on cellulose acetate and can be used to measure the molecular weight of the adsorbate. This sugar also undergoes optical rotations when it interacts with some dyes such as germanium tetrachloride. 1,5-α-L-Arabinotriose has many uses including: as a solute in chloride ion chromatography; as an absorbent in filtration experiments; and as a parameter for calculating thermodynamics for reactions involving hydrogen transfer.</p>

<p>Sialylated tetrasaccharide found in human milk, possible health benefits for the neonate by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.</p>

<p>A2G1 Glycan, 2-AB labelled is a monosaccharide which is modified with fluorine. A2G1 Glycan, 2-AB labelled is used in the synthesis of complex carbohydrate structures. It has been shown to be useful for click modification, methylation and polysaccharide synthesis. This compound can also be custom synthesized to order. The purity of this product is high and it is available in a range of CAS numbers.</p>

<p>Benzyl 4- O- b- D- glucuronyl-b- D- xylopyranoside is a synthetic derivative of benzyl 4- O- b- D- glucuronylxylose. It has been shown to be a good substrate for glycosylation, click modification and fluorination. This product has been custom synthesized for the synthesis of complex carbohydrate, which is an oligosaccharide. It is also used in methylation reactions.</p>

<p>This is a custom synthesis of a complex carbohydrate. The CAS number is not available and the polysaccharide has been modified. It has been glycosylated, methylated, and fluorinated. It is high purity and the sugar sequence is a custom synthesis.</p>

<p>Sucrose-6-phosphate sodium is a transcriptional regulator that belongs to the group of sugar phosphate ions. Sucrose-6-phosphate sodium regulates the transcription of genes involved in the synthesis of polysaccharides, such as sucrose and starch. This compound plays an important role in the metabolism of plants and has been shown to regulate hydrogen bond formation, photosynthetic activity, glycosidic bond formation, polymerase chain reactions, and regulatory sequences. The optimum pH for this compound is 7.0, with enzyme activities between pH 6.0 and 8.5. Sucrose-6-phosphate sodium also has been shown to regulate root formation and phosphorus pentoxide production in corynebacterium glutamicum.</p>

<p>GD1a ganglioside is one of the major gangliosides in neuronal and glial membranes. It has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acids linked α2,3/α2,8 to the inner galactose residue, α2,3 to the outer galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD1a ganglioside interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GD1a ganglioside plays a role in viral infection as it is a receptor for viral glycoproteins in rotavirus and paramyxovirus 1. The hexasaccharide GD1a moiety was also found on a glycoprotein that acts as a receptor for adenovirus type 37. GD1a ganglioside also interacts with botulinum neurotoxin (BoNT) and is crucial for its entry into cells (Kolter, 2012). The functional significance of ammonia in the brain is not fully understood see: (Modi, 1994).</p>

<p>N,N',N''-Triacetylchitotriose is a chiral compound that is formed from the acetylation of chitin. It has been shown to be an antigen for monoclonal antibodies and a model system for exploring the enzymatic hydrolysis of chitin. N,N',N''-Triacetylchitotriose can be used to investigate the catalytic mechanism of chitinase enzymes, which are involved in breaking down the polysaccharide chitin. It has also been shown to have bioactive properties, such as inhibiting lectins and binding with mannose receptors.</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>Melezitose is a non-reducing trisaccharide that is produced by many plant sap-consuming insects, such as aphids (e.g. Cinara pilicornis).  Melezitose is a component of honeydew which acts as an attractant for ants and also as food for bees. Partial hydrolysis of melizitose releases glucose and turanose, an isomer of sucrose.</p>

<p>4-Aminophenyl 1,3-a-1,6-a-D-mannotriose is a custom synthesis of the complex carbohydrate Oligosaccharide. It belongs to the group of saccharides and has a CAS number. This product is modified with methylation and glycosylation and is made up of a series of monosaccharides linked by alpha (1,4) or beta (1,2) glycosidic bonds. 4-Aminophenyl 1,3-a-1,6-a-D-mannotriose may be fluorinated during its synthesis using an electrophilic substitution reaction. This product is synthetic and has high purity.</p>

<p>1,4-β-D-Xylotriose is a pentose sugar that is the main component of hemicellulose. It is found in plant cell walls and has been studied using surface methodology to determine the covalent linkages and structure of 1,4-β-D-Xylotriose. Xylotrioses are also used as a substrate for enzyme reactions and have shown to have a number of enzymatic activities, including glycosidases, cellulases, xylanases, and arabinofuranosidases. Xylotrioses are also part of complex enzyme models that can be used to study disulfide bonds. Xylotrioses are polymers that are important for structural analysis due to the presence of β-1,4 links. The genome DNA has been found to contain many genes coding for xylanase enzymes.</p>

<p>N-Acetylallolactosamine is a lectin that has been shown to have an acceptor for the oligosaccharide, n-acetylllactosamine. It is synthesized by alkaline hydrolysis of allolactose, which is a lactose metabolite. N-Acetylallolactosamine can be used as a growth factor in the treatment of wounds and burns. This protein can also be used as a diagnostic tool to detect different types of cells in the blood stream.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose, with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarobiose is reported to exhibit skin moisturising and whitening properties.</p>

<p>Mannotetraose squarate is a modified oligosaccharide that is synthesized from mannose and tetraose. It has high purity, which is an advantage over natural oligosaccharides, and can be used in the synthesis of other carbohydrates. Mannotetraose squarate has a CAS number of 385842-90-0, which can be found on the ChemSpider database.</p>

<p>Paromamine is a chemical compound that inhibits protein synthesis by enzymatic inactivation. It has been shown to have a broad spectrum of antibacterial activity against Gram-positive and Gram-negative bacteria. Paromamine also has the ability to inhibit bacterial growth at high salt concentrations, making it an attractive candidate for development as an oral antibiotic drug. Paromamine is synthesized from natural products, such as salicylaldehyde or phenylhydrazine, which are readily available and inexpensive. The reaction mechanism for the formation of paromamine starts with dehydration of the hydroxyl group on the hydrazine to form a carbonyl group. This carbonyl group reacts with sephadex g-100 to form a cyanohydrin. The cyanohydrin reacts with ammonia to form an amide bond between the two nitrogen atoms in the molecule, which forms paromamine.</p>

<p>The "tallowate"€™ esters are probably the best known derivatives of sucrose and many attempts have been made to commercialise them in order to exploit their excellent surfactant functionalities.  The most functional products are the mono- and diesters of the tallow acids (stearic, palmitic, oleic) with hydrophile-lipophile balance (HLB) values that lend themselves to surfactant applications in foods and cosmetics.  They also have other uses, for example in coating fruits with a semipermeable membrane that acts as a preservative.  Manufacturing economics have prevented these products from mass production and they remain in niche applications.</p>

<p>An α-anomer, obtained by crystallization at low temperature, can be dehydrated to stable form above 130°C or an unstable (hygroscopic) form at lower temperatures. An example of the applications for α-Lactose monohydrate is in dry powder inhalers.  These are devices that deliver medication to the lung in the form of a dry powder generating an aerosol directly from the drug powder or mixture, using an excipient such as lactose monohydrate.</p>

<p>D-Cellopentose heptadecaacetate is a fluorinated, monosaccharide that is synthesized from the sugar cellobiose. It is an oligosaccharide and a complex carbohydrate with one of its glycosidic bonds modified by methylation. D-Cellopentose heptadecaacetate has been shown to be effective in inhibiting glycosylation reactions and can be used as a sugar substitute or for custom synthesis. This product has been shown to have high purity and is available at CAS No. 83058-38-2.</p>

<p>GD2 (shown as sodium salt) has a core trisaccharide structure (GalNAc-b-1,4-Gal-b-1,4-Glc) with its two sialic acids linked b-2,3/b-2,8 to the inner galactose residue and ceramide linked to position 1 on the reducing terminal glucose residue. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities.  It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>Kestoheptaose is a long-chain inulin with a molecular weight of 1,000 Da. It is found in the plant family Asteraceae and is the only natural polysaccharide with seven glucose units. Kestoheptaose has been shown to be involved in the regulation of muscle glycogen levels and can be used as a supplement for athletes or those who are active. The biochemical functions of Kestoheptaose have been validated using an oral ethanol extract, which was shown to increase muscle glycogen levels by up to 132%. This extract also decreased malondialdehyde concentrations by up to 41% and increased urea nitrogen levels by up to 89%.</p>

<p>A antigen pentasaccharide Type I, possible use in antiviral development</p>

<p>NGA2F Glycan is a complex carbohydrate that is synthesized by the enzymatic transfer of an N-acetylgalactosamine (GalNAc) residue to a serine or threonine residue on protein. It is modified with methylation, Click modification, and fluorination. NGA2F Glycan has two binding sites for 2-AB labelled monosaccharides. The glycosylation site is located at the non-reducing end of the molecule, while the oligosaccharide site is located at the reducing end of the molecule.</p>

<p>Galactofuranose pentasaccharide PEG6-NH-sp-biotin is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Galactofuranose pentasaccharide PEG6-NH-sp-biotin is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>N-Glycolylneuraminic acid dimer sodium salt is a synthetic sugar that is a glycosylat of N-glycolylneuraminic acid. It is soluble in water and has a CAS number of 1114-12-3. The product has been modified with methyl groups and is available for custom synthesis. It can be used as an intermediate for the synthesis of oligosaccharides, or it can be modified to form complex carbohydrates. This product has been fluorinated and is high purity, making it ideal for use in Click chemistry applications.</p>

<p>Neutral difuco hexasasaccharide naturally present in human breast milk</p>

<p>Anhydro maltose found in the pyrolysis products of cellulose</p>

<p>Sucrose dodecanoate is a sugar ester that has been shown to be a 5-HT agonist. It is used as an absorption enhancer for the treatment of choroidal neovascularization. Sucrose dodecanoate was also found to have trypsin-like protease activity and cyclic peptide properties. This drug has been shown to increase insulin sensitivity and growth factor levels in animal models, which may be due to its effects on serine proteases. Sucrose dodecanoate is available as a pharmaceutical dosage form containing fatty acid esters at a concentration of 10%. It has a viscosity of approximately 100 cP, which is expected to provide good bioavailability.</p>

<p>Chondroitin disaccharide Δdi-4S disodium salt (α-ΔUA-[1→3]-GalNAc-4S) comprises a sulfated N-acetylgalactosamine (GalNAc) and a dehydro glucuronic acid (GlcA) unit by the [1→3] linkage . It can used as a substrate for the identification and characterization of enzymes such as Clostridium perfringens unsaturated glucuronyl hydrolase.</p>

<p>Used to differentiate microorganisms based on their metabolic properties.</p>

<p>5-O-(a-D-[6,6'-2H2]Glucopyranosyl)-D-fructopyranose is a custom synthesis carbohydrate that is an oligosaccharide. It is a saccharide with a general formula of C6H10O5. One of its modifications is methylation. This product has been fluorinated and modified with the click reaction to create a glycosylated sugar. 5-O-(a-D-[6,6'-2H2]Glucopyranosyl)-D-fructopyranose is not radioactive and has high purity. It is also a polysaccharide that contains glucose monomers that are linked by glycosidic bonds to form branched chains of 10 or more units. The product has an appearance of white powder, and it can be used as an additive for pharmaceuticals, food products, and cosmetics.</p>

<p>Please enquire for more information about 4-O-{[(6-Azidoethoxy)ethoxy]ethyl}-β-D-galactopyranosyl-2-deoxy-α-D-glucopyranose-2,1-oxazoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-a-D-galactopyranoside is a lectin that binds to the terminal galactose of b-D-galactopyranosides. It has been shown to be a potent inhibitor of cellular death and is able to bind to the surface of cells, preventing their destruction by the immune system or other natural factors. The binding site for MGA is found on cell membranes, and it can also act as an antiinflammatory agent. MGA has also been shown to inhibit interactions between proteins, which may lead to changes in protein synthesis and regulation. Lectins are proteins that bind to specific carbohydrates on the surfaces of cells. They are part of a group called glycoproteins and are often used as probes in techniques such as lectin histochemistry and immunohistochemistry.</p>

<p>4-Methoxyphenyl 4-O-[2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3,6-di-O-(3,4,6,-tri -O acetyl 2 deoxy 2 phthalimido b D glucopyranosyl) b D mannopyranosyl] 3,6 di O benzyl 2 deoxy 2 phthalimido b D glucopyranoside (MPP) is a carbohydrate that belongs to the group of saccharides. It is an oligosaccharide sugar with a molecular weight of 1029.5 Da. This compound has been custom synthesized and is available in high purity. MPP is an ester of 4 methoxyphenol and 4 O-[2 O-(3,4,6 tri O acetyl 2 deoxy</p>

<p>1,2,3-Tri-O-acetyl-5-O-benzoyl-4-C-fluoromethyl-D-ribofuranose is an organic compound. It is a triacetate of 5'-O-(4,6'-dichloroacetyl)-1,2,3:5',6'-tetraethylideneuridine and a fluorinated derivative of ribofuranose. The chemical formula for 1,2,3:5',6'-tetraethylideneuridine is C9H14F8N2O8 and the molecular weight is 498.17 g/mol.</p>

<p>Ganglioside GM1 has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue, ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009), and is abundant in all mammalian brains, where it covers 10%-20% of the total ganglioside mixture. Ganglioside GM1 is found in epithelial membranes and is a key element for the detection of bacterial toxicity and viral infection. It is the intestinal receptor for cholera toxin, the B-subunits of heat-labile toxin (LTB) from E.coli, for rotavirus, and simian virus 40. GM1 functions as a neurotrophic and neuroprotective compound and has been used therapeutically for diabetic and peripheral neuropathies. It also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>

<p>Ganglioside GM3 (sodium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as: lung, brain and melanomas, where it is over expressed. It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function and immune disorders (e.g., allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>Produced from high maltose syrup by treatment with transglucosidase</p>

<p>Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. The potential clinical utility of galactosyllactose warrants investigation.</p>

<p>1,4-beta-D-xylohexaose is a sugar that belongs to the group of xylooligosaccharides. It is an enzymatic inactivator that binds to the enzyme hydrolase family. Xylooligosaccharides are found in plant cell walls, where they can be used as a carbon source by termites. 1,4-beta-D-xylohexaose has been shown to be most active against neutral ph, but it is not active against acidic ph. The enzyme hydrolase family is inhibited by binding with 1,4-beta-D-xylohexaose and this prevents hydrolysis of carbohydrates, which includes glycosidic bonds.br&gt;br&gt;<br>1,4-beta-D-xylohexaose has also been shown to be beneficial for sustainable agriculture practices as it inhibits enzymes that break down xylooligosaccharides</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>4-Methoxyphenyl 4-O-(3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3,6-di-O-benzyl-2-deoxy -2 -phthalimido -b -D -glucopyrano side is a custom synthesis of a complex carbohydrate. It has a CAS number of 140615‑82‑3 and can be found in glycosylations, carbohydrates, methylation, sugar, fluorination. It is high purity with a lot of modifications.</p>

<p>Produced from starch by partial hydrolysis. White hygroscopic spray-dried powder, easily digestible, either moderately sweet or almost flavorless (depending on the degree of polymerisation).</p>

<p>Mainly a mixture of Lacto-N-tetraose, Lacto-N-neo-tetraose, Lactodifucotetraose</p>

<p>Disaccharide; substrate for glucanases and laminaribiose phosphorylase</p>

<p>Alpha-1,4-glucopentasaccharide derived from starch by hydrolysis and chromatography</p>

<p>Blood group antigen with spacer arm</p>

<p>4-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is a methylated, custom synthesized monosaccharide with an Oligosaccharide and Polysaccharide. It is a Carbohydrate with Fluorination and complex carbohydrate. The chemical modification of this molecule includes Click modification and Monosaccharide. This molecule is synthesized using the methylation, Custom synthesis, Click modification, CAS No., Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate, High purity and Modification methods.</p>

<p>Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. This product has a 13C heavy-label and so can be used in applications such as metabolic tracing and quantitative mass spectrometry.</p>

<p>Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification.<br>Oligosaccharide. Saccharide. CAS No. Polysaccharide. Glycosylation. Sugar. Carbohydrate complex carbohydrate<br>Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide Synthetic Click modification Oligosaccharide saccharide CAS No Polysaccharide Glycosylation sugar Carbohydrate complex carbohydrate</p>

<p>Thiodiglucoside is a plant glycoside that is used as a preparative agent for the isolation of active substances from lymphocytes. It can be used in chromatographic and inhibition studies to determine the binding sites on lymphocytes. Thiodiglucoside has been shown to bind to lectins and inhibit protein synthesis in activated lymphocytes. This glycoside also inhibits the constriction of smooth muscle cells, which may be due to its inhibition of protein synthesis. The physiological function of thiodiglucoside is not yet fully understood; however, it is known that this compound binds to macropores and affects subunits within the cell membrane.</p>

<p>Immobilised on Fractogel with glycosylamine formation of the monosaccharide</p>

<p>Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. This product has a 13C heavy-label and so can be used in applications such as metabolic tracing and quantitative mass spectrometry.</p>

<p>6-Deoxy-D-lactosylamine (6DLA) is a carbohydrate that belongs to the group of oligosaccharides. It is an N-substituted glycosylated sugar with a methyl ester at the 6 position. The chemical name for 6DLA is 6-deoxy-N,N′,N″-(2,3,4,6-tetra-O-acetyl)-β--galactopyranosyl-(1→4)-β--glucopyranoside and it has CAS number 59225-12-5. This product can be custom synthesized and offers high purity. It can also be modified in different ways to create new products such as fluorination or methylation.</p>

<p>4-Aminophenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-b-D-thioglucopyranoside is a custom synthesis that has been fluorinated and methylated. This modified saccharide has been synthesized from a monosaccharide and an oligosaccharide with the help of click chemistry.<br>The CAS number for this product is 60515-61-9.</p>

<p>3'-Sialylgalacto-N-biose sodium salt is a high purity synthetic glycosaminoglycan with a single sugar residue. This product has been custom synthesized for research purposes and may be used as a control in experiments. The chemical name of this product is 3'-sialylgalacto-N-biose sodium salt, and it has CAS number 1370359-76-4. It is important to note that this product is not available for sale at this time.</p>

<p>a1,3-Galactobiosyl b-methyl glycoside is a fluorinated saccharide that possesses the same chemical structure as N-acetylgalactosamine. It has been synthesized by click modification with methyl iodide and methyl bromoacetate. The synthesis of this compound was achieved by glycosylation of galactose with 1,3-diiodo-2,2'-bithiopropane followed by methylation of the resulting glycosylation product with methyl bromoacetate to form the desired compound. This carbohydrate can be used in a variety of applications including anti-inflammatory drugs, antibiotics, and cancer treatments.</p>

<p>1,4-D-Xylobiose, also called 4-O-(b-D-Xylopyranosyl)-D-xylopyranose, is a beta 1-4 linked disaccharide made of 2 xylose monomers. 1,4-D-Xylobiose is a low-calories sweetener that can be used as an alternative or additive to sucrose. Supplementing a high fat diet with 1,4-D-xylobiose has been shown to prevent and treat obesity in mice.</p>

<p>Kojitriose is a disaccharide composed of two glucose molecules. It has been shown to have insulin-sensitizing effects in animals and humans. Kojitriose binds to the surface of Streptococcus faecalis and prevents the growth of this bacteria. Kojitriose also has an inhibitory effect on mesenteroides, which are a type of bacterium found in the human gut. This disaccharide is enzymatically hydrolyzed to produce hydrogen fluoride, which inhibits the growth of Streptococcus faecalis and mesenteroides. The enzyme trehalase is responsible for this hydrolysis reaction, while hydroxyl groups act as nucleophiles that react with chloride ions to form hydrogen fluoride.</p>

<p>Ex starch-partial hydrolysis,food ingredient, moderatly sweet, easily digested</p>

<p>Detergent used for the solubilization of membrane proteins.  Important for the solubilization is the detergent-to-protein ratio. At low ratios (1:10) the membranes are lysed and large complexes of are formed containing protein, detergent, and membrane lipids. With progressively larger ratios smaller complexes are obtained. Finally, at ratios of 10:1 to 20:1 individual detergent-protein complexes are formed free of membrane lipids. To determine the optimal conditions it is important to vary both the detergent and the protein concentration (EMBL).</p>

<p>4-Methoxyphenyl 4-O-{2-O-acetyl-4-O-[2,4-di-O-(3,4,6-tri-O-acetyl-2,3,5,6 -tetra-O-[(triisopropylsilyl)oxy]-2,5 -dideoxyglucan]-b-(D)-glucopyranosyl)-3,4di O-[benzyl]-a-(D)-mannopyranosyl}b-(D)-mannopyranoside is a high purity custom synthesis sugar. It can be fluorinated and glycosylated with methylation and modification. This compound is an oligosaccharide that can be used as a monosaccharide or complex carbohydrate.</p>

<p>Allyl 2,4,6-tri-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3-O-benzyl a -D -mannopyranoside is a glycosylated oligosaccharide. It is synthesized from 3,4,6 tri O acetyl 2 deoxy 2 phthalimido b D glucopyranosyl chloride and allyl alcohol by the click reaction with sodium azide in the presence of palladium catalysis. This product has been fluorinated at the 6 position of allose. The purity of this product is high and it has been modified on the saccharide chain with methyl groups at the C1 and C2 positions of glucose. Allyl 2,4,6 tri O (3 4 6 tri O acetyl 2 deoxy 2 phthalimido b D gluc</p>

<p>2-O-b-D-Galactosylsucrose is a synthetic, fluorinated sugar that has been custom synthesized for your needs. It is a complex carbohydrate that has been modified with methylation and click chemistry. 2-O-b-D-Galactosylsucrose is a monosaccharide, polysaccharide, and saccharide that is soluble in water. It can be used as a research tool for glycobiology and glycosylation, or as an ingredient in industrial applications such as food processing and pharmaceuticals.</p>

<p>Used for studies of the D-lactose pathway by non-invasive techniques using ¹â¹F-NMR spectroscopy or positron emission from the ¹âžF-labeled compound.</p>

<p>GD3 ganglioside (shown as sodium salt) has a core disaccharide structure (Gal-1,4-Glc) with two sialic acids linked to the non-reducing galactose residue, and ceramide linked to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD3 ganglioside is a minor ganglioside in most normal tissues but plays a crucial role in the development of the brain; its presence is significantly reduced in adults. However, expression of GD3 ganglioside is increased in pathological conditions, such as, cancers and neurodegenerative disorders (Malisan, 2002). GD3 ganglioside was the first cancer-associated ganglioside discovered, that promotes adhesion and invasion of cancers. GD3 ganglioside and GD2 ganglioside are highly expressed in a various malignant cancers and have become potential targets for next-generation cancer therapy (Liu, 2018).</p>

<p>Man-1-Fuc is a fluorinated sugar with a mannose backbone. This compound can be custom synthesized and modified to meet your specific needs. It is used in research as an oligosaccharide, polysaccharide, saccharide, or carbohydrate. Man-1-Fuc has a high purity and is available at low cost. It can be used for complex carbohydrate synthesis or modification. The chemical name of this compound is methyl 1,6-diacetoxylidene-2,3-dihydroxypropane fucopentaose.</p>

<p>Trehalose is a naturally occurring disaccharide found in many organisms.Its role in nature is as versatile as its applications in the laboratory. Trehalose is synthesized by cells in response to stress and helps retaining the cellular integrity under tough conditions: An important function of Trehalose is to stabilize protein structures and to prevent proteins from their degradation. Researchers use Trehalosefor instance as a carbon source in selective microbiological media, as desiccation protectant and for cryoprotection.</p>

<p>Isolated from partial acetolysate of ivory-nut (Phytelephas macrocarpa) mannan</p>

<p>Tetra-mannuronic acid sodium salt (β-1,4-linked sodium mannuronotetraose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.  Oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

<p>PAA is poly[N-(2-hydroxyethyl)acrylamide], flexible polymer chain serves as an additional spacer. Mr approx. 30 kDa (according to gel-filtration, proteins as Mr markers). Carbohydrate content is 20% mol.</p>

<p>2-O-(β-D-galactopyranosyl)-D-glucose is a sugar that can be custom synthesized to meet your needs. It is an oligosaccharide, polysaccharide, and carbohydrate that has been modified with methylation, glycosylation, and carbonylation. This product is available in high purity and fluorination.</p>

<p>Please enquire for more information about 2-O-(a-D-Galactopyranosyl)-a-L-fucopyranosyl propylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Disialylated tetrasaccharide naturally present in human breast milk that has been identified as one of the binding sites of the C fragment of the clostridial tetanus toxin.</p>

<p>This comound is generally known as sucralfates and are medications primarily taken to treat active duodenal ulcers. They are also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers.  Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus. It also promotes bicarbonate production and acts like an acid buffer with cytoprotective properties.</p>

<p>The blood group H disaccharide is a custom synthesis, complex carbohydrate with an Oligosaccharide and CAS No. It is a Polysaccharide that can be modified by methylation or glycosylation. The blood group H disaccharide has a saccharide with a high purity and high purity. It is fluorinated at the 2' position of the sugar moiety in the backbone. The blood group H disaccharide can be synthesized using Click chemistry which involves coupling of two molecules in a single step. This process uses an azide-alkyne cycloaddition to covalently link two molecules together.</p>

<p>GA2-ganglioside is a ganglioside that is found in the membranes of cells. GA2-Ganglioside has been shown to inhibit the growth of tumors by binding to macrophages and T cells, which are two types of white blood cells. It has also been shown that GA2-Ganglioside can be used as a target for an antibody response against human HL-60 tumor cells. The antibody response induces cell lysis and reduces the size of the tumor. GA2-Ganglioside has also been shown to have anti-inflammatory properties, which may be due to its ability to bind to α subunits on bowel disease and infectious diseases, such as murine sarcoma virus, causing an antibody response that causes cell lysis and prevents replication of these viruses.</p>

<p>Man-4 N-glycan is an oligosaccharide that is modified with a methyl group at the 4th carbon atom. It has been synthesized in our laboratory, and can be customized according to your specifications. Man-4 N-glycan is highly pure and has a purity of 98% or higher. This product also has undergone click modification, which is a reaction between two molecules containing an azide and an alkyne. The resulting product contains a fluorine atom on the 4th carbon atom. Contact us for more information about this product.</p>

<p>3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-mannopyranose is a disaccharide that is part of the glycosaminoglycan family. It has an antigenic epitope that is recognized by antibodies, which are found in patients with rheumatoid arthritis and other autoimmune diseases. 3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-mannopyranose is also known as glucosamine.</p>