
Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
At CymitQuimica, we offer high-purity benzimidazoles and imidazoles for research in medicinal chemistry, pharmacology, and biotechnology.
Found 10354 products of "Benzimidazole and Imidazole Derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
1-(2-Trifluoromethylphenyl)imidazole
CAS:Formula:C10H7F3N2Purity:98.0%Color and Shape:SolidMolecular weight:212.1753-(2-(6-(tert-Butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutanone hydrochloride
CAS:Purity:97.0%Molecular weight:306.8299865722656[3-(2H-tetrazol-2-yl)-1-adamantyl]amine hydrochloride hydrate
Purity:95.0%Molecular weight:273.7699890136719{5-[1-(benzylamino)cyclohexyl]-1H-tetrazol-1-yl}acetic acid
CAS:Purity:95.0%Molecular weight:315.377014160156255,6-DIMETHYL-2-(PYRIDIN-3-YL)-1H-BENZO[D]IMIDAZOLE
CAS:Purity:95.0%Molecular weight:223.27900695800784-(1H-Benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:201.188995361328122-(1H-benzimidazol-2-ylthio)-1-cyclopropylethanone
CAS:Purity:95.0%Molecular weight:232.3000030517578(E)-2-(4-(1H-Imidazol-4-yl)styryl)-1H-indene-1,3(2H)-dione
CAS:Purity:95.0%Molecular weight:314.3439941406252-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine, Hydrochloride
CAS:Controlled ProductFormula:C9H9ClF3NO·ClHColor and Shape:NeatMolecular weight:276.08(-)-Donepezil
CAS:Controlled Product<p>Applications (-)-Donepezil is an isomer of Donepezil (D531750), a nootropic, acting as an inhibitor of acetylcholinesterase.<br>References Ohnishi, A., et al.: J. Clin. Pharmacol., 33, 1086 (1993), Galli, A., et al.: Eur. J. Pharmacol., 270, 189 (1994)<br></p>Formula:C24H29NO3Color and Shape:NeatMolecular weight:379.49Itraconazole N,N-Dioxide
Controlled Product<p>Stability Hygroscopic<br>Applications Itraconazole N,N-Dioxide is a derivative of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C35H38Cl2N8O6Color and Shape:NeatMolecular weight:737.63Luliconazole
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Luliconazole is an azole antifungal drug.<br>References Uhida, K., et al.: J. Infect. Chemother., 10, 216 (2004); Niwano, ., et al.: Antimicro. Agents Chemother., 42, 967 (1998),<br></p>Formula:C14H9Cl2N3S2Color and Shape:Off-White To Light YellowMolecular weight:354.28Hydroxy Itraconazole
CAS:Controlled Product<p>Applications A metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It is a COVID19-related research product.<br>References Saag, M., et al.: Antimicrob. Agents Chemother., 32, 1 (1988), Haria, M., et al.: Drugs, 51, 585 (1996), Kousoulos, C., et al.: Anal. Bioanal. Chem., 384,199 (2006),<br></p>Formula:C35H40Cl2N8O4Color and Shape:WhiteMolecular weight:707.65Lansoprazole Sulfone-d4
CAS:Controlled ProductFormula:C16H10D4F3N3O3SColor and Shape:NeatMolecular weight:389.382-Methyl-5-nitroimidazole-1-acetic Acid
CAS:Controlled Product<p>Applications 2-Methyl-5-nitroimidazole-1-acetic Acid is a metabolite of metronidazole with mutagenic activity.<br>References Chacko, M., et al.: Indian J. Exp. Biol., 25, 240 (1987)<br></p>Formula:C6H7N3O4Color and Shape:Light YellowMolecular weight:185.14Fenbendazole-d3
CAS:Controlled Product<p>Applications Labelled Fenbendazole (F246750). An anthelmintic (Nematodes).<br>References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),<br></p>Formula:C15H10D3N3O2SColor and Shape:Off White SolidMolecular weight:302.37Carbamazepine 10,11-Epoxide
CAS:<p>Applications A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Johannessen, S., et al.: Ther. Drug. Monit., 27, 710 (2005), Bialer, M., et al.: Expert Opin. Invest. Drugs, 15, 637 (2006), Williams, J., et al.: J. Clin. Pharmacol., 46, 258 (2006),<br></p>Formula:C15H12N2O2Purity:>97% by HPLCColor and Shape:NeatMolecular weight:252.275-Hydroxy Thiabendazole-13C2,15N
CAS:Controlled Product<p>Applications Labelled 5-Hydroxy Thiabendazole (H961200). 5-Hydroxy Thiabendazole is the major metabolite of Thiabendazole (T344150).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujitani, T., et al.: Food Chem. Toxicol., 29, 265 (1991), Mizutani, T., et al.: Chem. Res. Toxicol., 6, 174 (1993), Dalvie, D., et al.: J. Agric. Food Chem., 42, 2964 (2006),<br></p>Formula:C813C2H7N215NOSColor and Shape:NeatMolecular weight:220.236-Bromo-5-(2-fluoro-4-nitrophenoxy)-1-methyl-1H-indazole
CAS:Purity:95.0%Molecular weight:366.14599609375Methyl 5-Hydroxy-2-benzimidazolecarbamate
CAS:Formula:C9H9N3O3Color and Shape:NeatMolecular weight:207.19Omeprazole-d3 Sulfone
CAS:Controlled ProductFormula:C17H16D3N3O4SColor and Shape:NeatMolecular weight:364.43Oxcarbazepine-D4 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.Only available as a mixture of deuterated material:d-1: 1%d-2: 9%d-3: 35%d-4: 55%<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),<br></p>Formula:C152H4H8N2O2Color and Shape:Light Orange Colour PowderMolecular weight:256.299-Hydroxy Propantheline Bromide
CAS:<p>Applications A major impurity of the antimuscarinic agent Propantheline Bromide (P760900).<br>References Ford, B.L. et al.: J. Assoc. Off. Anal. Chem., 67, 934 (1984); Mourier, P.A.: Analusis, 17, 67 (1989);<br></p>Formula:C23H30NO4·BrColor and Shape:NeatMolecular weight:464.39(R)-Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity D<br>Applications (R)-Rivastigmine (Rivastigmine EP Impurity D) is a carbamate inhibitor of acetylcholinesterase used as a treatment of Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lucangioli, S. E., et al.: J. Chromatogr. A, 1081, 31-35 (2005); Bar-On, P., et al.: Biochem., 41, 3555-3564 (2002);<br></p>Formula:C14H22N2O2·C4H6O6Color and Shape:NeatMolecular weight:400.424-Desmethoxypropoxyl-4-chloro Rabeprazole
CAS:Controlled Product<p>Impurity Rabeprazole EP Impurity H (Lansoprazole EP Impurity F)<br>Applications 4-Desmethoxypropoxyl-4-chloro Rabeprazole (Rabeprazole EP Impurity H (Lansoprazole EP Impurity F)) is a process impurity of Rabeprazole (R070500).<br></p>Formula:C14H12ClN3OSColor and Shape:NeatMolecular weight:305.78Metronidazole-d4
CAS:Controlled Product<p>Applications Metronidazole-d4 is a labelled analog of Metronidazole (M338880). Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.<br>References Carballo, M., et al.: J. App. Toxicol., 29, 248 (2009), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C62H4H5N3O3Color and Shape:Light YellowMolecular weight:175.18Carbamazepine-d2,15N
CAS:Controlled ProductFormula:C15H10D2N15NOColor and Shape:Off White SolidMolecular weight:239.27Lansoprazole-d4
CAS:Controlled ProductFormula:C162H4H10F3N3O2SColor and Shape:NeatMolecular weight:373.39Isobutylsuccinic Acid
CAS:Controlled Product<p>Applications Isobutylsuccinic Acid was used to synthesize succinimide derivatives as inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.<br>References Groutas, W., et al.: Bioorg. Med. Chem., 3, 375 (1995);<br></p>Formula:C8H14O4Color and Shape:NeatMolecular weight:174.193-Cyano-5-methylhexanoic Acid
CAS:Controlled Product<p>Applications 3-Cyano-5-methylhexanoic Acid, a derivative of rac-Pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Taylor, C. at al.: Epilepsy Res., 14, 11 (1993); Field, M. et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H13NO2Color and Shape:NeatMolecular weight:155.19Ilaprazole
CAS:Controlled Product<p>Applications Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.<br>References Cao, S., et al.: Acta Pharmacol. Sin., 33, 1095 (2012); Wang, L., et al.: J. Clin. Gastroenterol., 45, 322 (2011)<br></p>Formula:C19H18N4O2SColor and Shape:NeatMolecular weight:366.442-Cyclohexyl-2-hydroxy-phenylacetic Acid
CAS:Controlled Product<p>Impurity Oxybutynin USP Related Compound A<br>Applications An intermediate in the synthesis of oxybutynin (O868525). Oxybutynin USP Related Compound A.<br></p>Formula:C14H18O3Color and Shape:WhiteMolecular weight:234.292-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid
CAS:Purity:95.0%Color and Shape:Solid, White - Pale yellow powderMolecular weight:274.2900085449219O-Hydroxyethyl Metronidazole
CAS:Controlled Product<p>Applications O-Hydroxyethyl Metronidazole is the hydroxy ethyl analogue and impurity of the antiprotozoal agent Metronidazole (M338880). O-Hydroxyethyl Metronidazole as well as other 1-substituted-2-methyl-5-nitroimidazoles showed potential antitrichomonal activity.<br>References Kajfez, F. et al.: J. Med. Chem., 11, 167 (1968);<br></p>Formula:C8H13N3O4Color and Shape:Yellowish SolidMolecular weight:215.21(S)-Pregabalin-13C3
CAS:Controlled Product<p>Applications (S)-Pregabalin-13C3, is the labeled analogue of (S)-Pregabalin (P704790), a S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C513C3H17NO2Color and Shape:Off-WhiteMolecular weight:162.2rac 5,6-Dehydro Pregabalin
CAS:Controlled Product<p>Applications 5,6-Dehydropregabalin is an impurity of the anticonvulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Formula:C8H15NO2Color and Shape:Off-WhiteMolecular weight:157.2110,11-Dihydro-10-hydroxy Carbamazepine-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Oxcarbazepine (O869250).<br>References Burkhart, C., et al.: Clin. Exp. Allergy, 32, 1635 (2002), Pearce, R., et al.: Drug Metab. Dispos., 30, 1170 (2002), Naisbitt, D., et al.: Mol. Pharmacol., 63, 732 (2003), Farrell, J., et al.: Br. J. Clin. Pharmacol., 57, 690 (2004),<br></p>Formula:C152H3H11N2O2Color and Shape:Off WhiteMolecular weight:257.301’-Hydroxy Midazolam-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.<br>References Dundee, J., et al.: Drugs, 28, 519 (1984), Galetin, A., et al.: Drug Metab. Dispos., 30, 1512(2002), Uchaipichat, V., et al.: Drug Metab. Dispos., 34, 449(2006), Lewis, B., et al.: Biochem. Pharmacol., 73, 1463(2007), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C182H5H8ClFN3OColor and Shape:White To Off-WhiteMolecular weight:346.80Voriconazole N-Oxide
CAS:Controlled Product<p>Applications A metabolite of Voriconazole (V760000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997), Geist, M., et al.: Antimicrob. Agents. Chemother., 50, 3227 (2006), Yamazaki, H., et al.: Drug. Metab. Dispos., 34, 1803 (2006), Yamazaki, H., et al.: Xenobiotica, 36, 1201 (2006),<br></p>Formula:C16H14F3N5O2Color and Shape:WhiteMolecular weight:365.31Mebendazole
CAS:Controlled Product<p>Applications Mebendazole is an Anthelmintic (Nematodes).<br>References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 16, 291 (1987)<br></p>Formula:C16H13N3O3Color and Shape:NeatMolecular weight:295.29(R)-Lansoprazole
CAS:<p>Stability Hygroscopic<br>Applications The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColor and Shape:Off White To Dark BrownMolecular weight:369.362-Methoxy-4-nitroaniline
CAS:<p>Applications 2-Methoxy-4-nitroaniline is a derivative of 4-Nitroaniline (N491770), which is used in the synthesis of photorefractive polymers, as novel chromophores in analytical study. As well, due to the absorption spectrum associated with 4-Nitroaniline, it is used to determine catechol derivatives in syntheses.<br>References Nagaraja, P. et al.: J. Pharm. Biomed. Anal., 25, 417 (2001);<br></p>Formula:C7H8N2O3Color and Shape:YellowMolecular weight:168.153-Methoxy-temazepam
CAS:Controlled ProductFormula:C17H15ClN2O2Color and Shape:Off-White To Light YellowMolecular weight:314.77Triazolam
CAS:Controlled Product<p>Applications Sedative, hypnotic.Controlled substance (depressant).<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4Color and Shape:WhiteMolecular weight:343.21Triclabendazole Sulfoxide-D3
CAS:Controlled Product<p>Applications Triclabendazole Sulfoxide-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Formula:C14H6D3Cl3N2O2SColor and Shape:NeatMolecular weight:378.68Benzoylmetronidazole
CAS:Controlled Product<p>Applications Benzoylmetronildazole is a new class of antiglycation agents used to treat diabetes mellitus. Benzoylmetronildazole is also a derivative of Metronidazole (M338880), an antibacterial in the treatment of rosacea.<br>References Zeb, A., et al.: Med. Chem., 8, 846 (2012); Kumari, N., et al.: Curr. Drug. Deliv., 9, 74 (2012); Elosta, A., et al.: Curr. DIabetes. Rev., 8, 92 (2012);<br></p>Formula:C13H13N3O4Color and Shape:WhiteMolecular weight:275.26Itraconazole
CAS:Controlled Product<p>Applications Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993);<br></p>Formula:C35H38Cl2N8O4Color and Shape:White To Off-WhiteMolecular weight:705.634-Methylenepiperidine Hydrochloride
CAS:Controlled Product<p>Applications 4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.<br>References Vice, S., et al.: J. Org. Chem., 66, 2487 (2001);<br></p>Formula:C6H11N•(HCl)Color and Shape:NeatMolecular weight:97.1636465-Hydroxy Omeprazole-d3 Sodium Salt
CAS:Controlled ProductFormula:C17H15D3N3NaO4SColor and Shape:White To Light YellowMolecular weight:386.42N-methyl-1-(1-phenyl-1H-tetrazol-5-yl)cyclohexanamine
CAS:Purity:95.0%Molecular weight:257.34100341796875Lamotrigine
CAS:Controlled Product<p>Applications An anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C9H7Cl2N5Color and Shape:NeatMolecular weight:256.09Midazolam Maleate
CAS:Controlled ProductFormula:C18H13ClFN3·C4H4O4Color and Shape:White To Off-WhiteMolecular weight:441.841-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxylic Acid
CAS:Controlled Product<p>Applications 1-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxylic Acid is a metalobilite of Midazolam(M343000) which is a anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000),<br></p>Formula:C18H12ClFN2O3Color and Shape:NeatMolecular weight:358.75Albendazole-d7
CAS:Controlled Product<p>Applications Labelled Albendazole (A511610). An anthelmintic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C12H8D7N3O2SColor and Shape:NeatMolecular weight:272.37Efinaconazole-N-oxide
CAS:Controlled Product<p>Applications Efinaconazole-N-oxide is a degradation product and potentially a metabolite of the anti-fungal drug Efinaconazole (E435070).<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4O2Color and Shape:NeatMolecular weight:364.39Carbamazepine-d2 (Major)
CAS:Controlled Product<p>Applications Labelled Carbamazepine (C175840). Used in treatment of pain associated with trigeminal neuralgia. Anticonvulsant.<br>References Stenger, E.G., et al.: Med. Exp., 11, 191 (1964), Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979), Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Formula:C15H10D2N2OColor and Shape:NeatMolecular weight:238.28rac-Pregabalin
CAS:Controlled Product<p>Applications A GABA analogue used as an anticonvulsant.Controlled substance in the United States.Not controlled in Germany<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H17NO2Color and Shape:White SolidMolecular weight:159.23rac 5-Hydroxymethyl Tolterodine-d14
CAS:Controlled ProductFormula:C22H17D14NO2Purity:90%Color and Shape:NeatMolecular weight:355.57Rufinamide-15N,d2
CAS:Controlled Product<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N315NOColor and Shape:White SolidMolecular weight:241.2rac Desethyl Oxybutynin-d5 Hydrochloride
CAS:Controlled Product<p>Applications A labelled metabolite of the drug Oxybutynin (D289475). Used in the treatment of incontinence.<br>References Hughes, K., et al.: Xenobiotica, 22, 859 (1992), Oki, T., et al.: Biol. Pharm. Bull., 24, 491 (2001), Fetscher, C., et al.: Br. J. Pharmacol., 136, 64 (2002), Zobrist, R., et al.: Pharm. Res., 20, 103 (2003)<br></p>Formula:C20H22D5NO3·HClColor and Shape:White To Off-WhiteMolecular weight:334.47 + (36.46)Propantheline Bromide
CAS:Controlled Product<p>Applications Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.<br>References Levin, R. et al.: Neurol. Urodyn., 1, 221 (1982); Daniotti, S. et al.: Br. J. Pharmacol., 82, 305 (1984); Moller, J. et al .: Acta Med. Scand., 184, 201 (1968);<br></p>Formula:C23H30NO3·BrColor and Shape:White To Off-WhiteMolecular weight:448.39N-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl Lansoprazole
CAS:Controlled Product<p>Applications Lansoprazole (L175000) impurity.<br>References Wallmark, B., et al.: J. Gastroenterol., 20, 37 (1985), Barradell, L., et al.: Drugs, 44, 225 (1992), Reddy, K., et al.: Pharmazie, 65, 994 (2006),<br></p>Formula:C25H22F6N4O3SColor and Shape:Beige To Light BrownMolecular weight:572.52Cyanoacetamide
CAS:<p>Applications Cyanoacetamide has been used in photometric and fluorimetric postcolumn labeling.<br>References Honda S., et. al.: Anal. biochem., 134, 483(1983)<br></p>Formula:C3H4N2OColor and Shape:NeatMolecular weight:84.07676-Hydroxy-2-mercaptobenzimidazole
CAS:Controlled ProductFormula:C7H6N2OSColor and Shape:NeatMolecular weight:166.201'-Hydroxy Triazolam
CAS:Controlled Product<p>Applications A metabolite of Triazolam (T767380(M)), which is a sedative; a controlled substance (depressant).<br>References Boxenbaum, H., et al.: J. Pharm. Pharm. Sci., 2, 47 (1999), Perloff, M., et al.: J. Pharmacol. Exp. Ther., 292, 618 (2000), Patki, K., et al.: Drug Metab. Dispos., 31, 938 (2003),<br></p>Formula:C17H12Cl2N4OColor and Shape:Light GreenMolecular weight:359.21Modafinil Carboxylate Methyl Ester
CAS:Controlled Product<p>Impurity Modafinil EP Impurity C<br>Applications Modafinil Carboxylate Methyl Ester (Modafinil EP Impurity C) is a Modafinil derivative.<br>References Lehr, H., et al.: J. Med. Chem., 6, 136 (1963), Saikawa, I., et al.: Chem. Pharm. Bull., 33, 5534 (1985),<br></p>Formula:C16H16O3SColor and Shape:NeatMolecular weight:288.361-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
CAS:<p>Impurity Miconazole EP Impurity F<br>Applications 1-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole (Miconazole EP Impurity F) is an impurity of Miconazole (M342505), an antifungal (1,2) agent (topical).<br>References 1. Godefroi, E. et al.: J. Med. Chem. 1969 Sep;12(5):784-91.2. Brugmans, J. et al.: Arch Dermatol. 1970 Oct;102(4):428-32.<br></p>Formula:C18H14Cl4N2OColor and Shape:NeatMolecular weight:416.135-Hydroxy Omeprazole Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications The main metabolite of Omeprazole.<br>References Renberg, L., et al.: Drug Metab. Dispos., 17, 69 (1989), Calabresi, L., et al.: Pharmacol. Res., 49, 493 (2004), Yin, O., et al.: J. Clin. Pharmacol., 44, 582 (2004),<br></p>Formula:C17H18N3NaO4SColor and Shape:White To Light YellowMolecular weight:383.404-Isobutyl-2-pyrrolidinone (pregabalin lactam impurity)
CAS:<p>Impurity Pregabalin USP Related Compound C<br>Applications Pregabalin (P704800) intermediate. Pregabalin USP Related Compound C<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColor and Shape:Light YellowMolecular weight:141.21(R)-Pregabalin
CAS:Controlled Product<p>Impurity Pregabalin USP Related Compound A<br>Applications R-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia (less potent than the S-Enantiomer). Pregabalin USP Related Compound A.<br>References Field, M.J. et al.: Br. J. Pharmacol., 132, 1 (2001); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993);<br></p>Formula:C8H17NO2Color and Shape:WhiteMolecular weight:159.23Methyl Methanesulfonate
CAS:<p>Applications Methyl Methanesulfonate is used as a reagent in the synthesis of 2-Methyllamotrigine (M315350); an impurity of Lamotrigine (L173250) which is an anticonvulsant that inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Also used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986); Grunze, et al.: Neuropsychobiology, 38, 131 (1998); Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999)<br></p>Formula:C2H6O3SColor and Shape:Colourless LiquidMolecular weight:110.134-Methyl Mebendazole
CAS:Controlled Product<p>Applications Mebendazole (M200500) related compound as anthelmintic agent.<br>References Raeymaekers, A.H.M., et al.: Arzneim.-Forsch., 28, 586 (1978),<br></p>Formula:C17H15N3O3Color and Shape:NeatMolecular weight:309.32Voriconazole-d3
CAS:Controlled Product<p>Applications Labelled Vorizonazole (V760000), used as an antifungal (systemic). An Ergosterol Biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C162H3H11F3N5OColor and Shape:White To BeigeMolecular weight:352.33Modafinil-d5 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Labelled Modafinil (M482502). Modafinil is an α-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease.This is a controlled substance (stimulant).<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999)<br></p>Formula:C152H5H10NO2SColor and Shape:NeatMolecular weight:278.38Iminostilbene
CAS:Controlled Product<p>Impurity Carbamazepine EP Impurity D<br>Applications A metabolite of Carbamazepine (CBZ) (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001),<br></p>Formula:C14H11NColor and Shape:Yellow To Dark OrangeMolecular weight:193.24Omeprazole Sulfone N-Oxide
CAS:<p>Impurity Omeprazole EP Impurity I<br>Applications Omeprazole Sulfone N-Oxide (Omeprazole EP Impurity I) is a metabolite of Omeprazole. Impurity I.<br>References Stevens, C.M., et al.: J. Biol. Chem., 75, 182 (1950), Okamoto, S., et al.: Biochem. Biophys. Res. Commun., 101, 440 (1981)<br></p>Formula:C17H19N3O5SColor and Shape:NeatMolecular weight:377.412-((1,3-DIOXOISOINDOLIN-2-YL)METHYL)OXAZOLE-4-CARBOXYLIC ACID
CAS:Purity:95.0%Molecular weight:272.216003417968754'-Ethoxyacetophenone
CAS:<p>Applications 4'-Ethoxyacetophenone, is an acetophenone derivative that can be used as an antibacterial agent. It is a reagent for plymerization. It can also be used as a flavoring agent in fabricating cigarettes with flavored filter tips.<br>References Sivakumar, P., et al.: Chem. Bio. Drug Design, 72, 303 (2008); Mathis, D. E., Beitraege zur Tabakforschung Int., 12, 1 (1983);<br></p>Formula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.20Rivastigmine N-Oxide (Technical Grade)
CAS:Controlled Product<p>Applications Rivastigmine N-Oxide is an impurity of Rivastigmine (R541000, Tartrate Salt) which is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Formula:C14H22N2O3Color and Shape:Light Yellow LiquidMolecular weight:266.34para-Clotrimazole Isomer
CAS:Controlled Product<p>Impurity Clotrimazole EP Impurity B<br>Applications para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.<br>References Buechel, K.H. et al.: Drugs Made Ger., 15, 79 (1972); Bachmann, K. et al.: Pharmacol. Res., 50, 237 (2004);<br></p>Formula:C22H17ClN2Color and Shape:NeatMolecular weight:344.845-Desamino 5-Oxo-2,5-dihydro Lamotrigine
CAS:Controlled Product<p>Impurity Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C<br>Applications 5-Desamino 5-Oxo-2,5-dihydro Lamotrigine (Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C) is an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Formula:C9H6Cl2N4OColor and Shape:White SolidMolecular weight:257.08(2-Oxopyrrolidin-1-yl)acetic Acid
CAS:<p>Impurity Piracetam Impurity D<br>Applications (2-Oxopyrrolidin-1-yl)acetic acid is a reagent in the preparation of pyrazolopyridines as PDE4B inhibitors.<br>References Mitchell, C. J., et al.: Bioorg. Med. Chem. Lett., 20, 5803 (2010);<br></p>Formula:C6H9NO3Color and Shape:Off-WhiteMolecular weight:143.14Metronidazole
CAS:<p>Applications Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.<br>References Carballo, M., et al.: J. App. Toxicol., 29, 248 (2009), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C6H9N3O3Color and Shape:White To Off-WhiteMolecular weight:171.15Rufinamide
CAS:<p>Applications Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H8F2N4OColor and Shape:White To Off-WhiteMolecular weight:238.192,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
CAS:Controlled Product<p>Applications An intermediate in the synthesis of Itraconazole.<br></p>Formula:C22H27N5O2Color and Shape:NeatMolecular weight:393.48Fenbendazole Sulfoxide-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Fenbendazole (F246750).<br>References McKellar, Q., et al.: J. Vet. Pharmacol. Ther., 13, 223 (1990), De Ruyck, H., et al.: Food Control., 11, 165 (2000),<br></p>Formula:C152H3H10N3O3SColor and Shape:White To Off-WhiteMolecular weight:318.37Iso Letrozole
CAS:<p>Impurity Letrozole EP Impurity A; Letrozole USP Related Compound A<br>Applications Isoletrozole (Letrozole EP Impurity A) is an impurity of Letrozole (L330100). Letrozole impurity A as per USP.<br>References Fleming, F.F., et al.: J. Med. Chem., 53, 7902 (2010),<br></p>Formula:C17H11N5Color and Shape:NeatMolecular weight:285.30

