Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10355 products of "Benzimidazole and Imidazole Derivatives"
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Carbendazim
CAS:<p>Carbendazim is a fungicide that inhibits the growth of fungi and bacteria. It has been shown to be potent inducers of polymerase chain reaction (PCR) amplification, with a rate constant of 0.0103 per minute. Carbendazim also has a significant effect on electrochemical impedance spectroscopy (EIS). The EIS analysis was used to compare carbendazim-treated cells with untreated cells, which showed that carbendazim causes an increase in the resistance across the cell membrane. This research suggests that carbendazim may be genotoxic, as it increased the amount of DNA damage observed in wild-type strains and altered the optical properties of DNA. Carbendazim is also an effective inhibitor of nitrite ion oxidation and colloidal gold deposition, which has led to its use as a water vapor control agent for plants.</p>Formula:C9H9N3O2Purity:Min. 95%Color and Shape:PowderMolecular weight:191.19 g/mol6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
CAS:<p>6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is a metabolite that can be found in the urine and blood of humans. It has been shown to have cytotoxic effects on human lymphocytes and erythrocytes. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is used as an impurity standard for HPLC analysis and as a reference compound for pharmacopoeia. This chemical is also used in the synthesis of some drugs. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is not listed in any pharmacopoeia or natural product database.</p>Formula:C9H7Cl2N5Purity:Min. 95%Color and Shape:White PowderMolecular weight:256.09 g/mol1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine
CAS:<p>1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine is an analytical standard and a drug product. It is a synthetic compound that has been shown to have pharmacological effects similar to those of the analgesic or opioid drugs. 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine can be used as an impurity standard for HPLC analyses as well as metabolic studies. This compound is also known to have potential interactions with other drugs.</p>Formula:C24H27NO3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:377.48 g/mol5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity)
CAS:<p>5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity) is an analytical standard used as a reference in HPLC assays for donepezil. It is also a metabolite of donepezil and has been found to have pharmacological activity similar to that of the parent compound. This impurity is present in donepezil drug products at levels up to 0.5%.</p>Formula:C17H21NO3Purity:Min. 95%Molecular weight:287.35 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide is a cyclic sulfoxide that has shown to be a potent inhibitor of gastric acid secretion. It is an important intermediate in the synthesis of esomeprazole magnesium, a proton pump inhibitor used to treat gastroesophageal reflux disease and other gastrointestinal disorders. 5-Methoxy-2-[(4-methoxy 3,5 dimethyl 2 pyridinyl) methyl] sulphonyl]-1H benzimidazole N oxide is also known as (RS)-N-[4-(4′ methoxyphenyl)-3,5 dimethylpyrazol -2 - ylmethyl] methanesulfonamide. This compound has been shown to have a polymorphic form with two different</p>Formula:C17H19N3O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:377.42 g/mol4-Desmethoxy omeprazole sulfide
CAS:<p>4-Desmethoxy omeprazole sulfide is a metabolite of omeprazole, a drug that is used to treat ulcers and gastroesophageal reflux disease. 4-Desmethoxy omeprazole sulfide is not an impurity in the production of omeprazole, but is present as a natural component of omeprazole. This compound has been shown to be an impurity standard for HPLC analysis. The pharmacopoeia defines 4-desmethoxy omeprazole sulfide as an API impurity in drug products. It is also being studied for its potential use in drug development and research and development.</p>Formula:C16H17N3OSPurity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:299.39 g/molN-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide
CAS:<p>N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide is a pharmaceutical dosage form that is titrated to achieve the desired therapeutic effect. It is used to treat epilepsy and bipolar disorder. Lamotrigine binds to sodium channels in nerve cells and blocks their opening. This prevents the influx of sodium ions that are necessary for neuronal transmission. Lamotrigine has been shown to have an anticonvulsant effect by reducing the frequency of seizures in patients with epilepsy.</p>Formula:C16H9Cl4N5OPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:429.09 g/molMethyl 2,2-dithienylglycolate
CAS:<p>Intermediate for tiotropium bromide synthesis</p>Formula:C11H10O3S2Purity:Min. 95%Color and Shape:White PowderMolecular weight:254.33 g/molN-(2-Phenethyl)benzamide
CAS:<p>N-(2-Phenethyl)benzamide (NPEB) is a molecule that belongs to the group of reactive molecules. It has been shown to be toxic to gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, but not gram-negative bacteria such as Escherichia coli. NPEB also has been shown to have locomotor activity in animals, which may be due to its ability to inhibit the mitochondrial electron transport chain and inhibit ATP production. NPEB's biological properties are well characterized. FTIR spectroscopy showed that this molecule has an amide functional group and is a small molecule with a molecular weight of 176.4 g/mol. This molecule was also found to be able to bind to mitochondria in animals.</p>Formula:C15H15NOPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:225.29 g/molAlbendazole sulfoxide
CAS:<p>Albendazole sulfoxide is a sulfoxide of albendazole. The molecular docking analysis of the two molecules showed that the sulfoxide group is located in the same position as the hydroxyl group on albendazole. It has been shown that this replacement of hydroxyl with a sulfoxide group increases the solubility and stability of albendazole, which may be due to hydrogen bonding interactions between these groups. Albendazole sulfoxide has been shown to be an effective treatment for infections caused by parasites such as helminths. However, it should not be used in combination with drugs that are metabolized by cytochrome P450 enzymes because it can inhibit their activity.</p>Formula:C12H15N3O3SPurity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:281.33 g/molDihydroxy diketo atorvastatin impurity
CAS:<p>Dihydroxy diketo atorvastatin impurity is a synthetic impurity that is generated by the metabolism of atorvastatin. This drug product is an analytical standard for the determination of purity, and can also be used to develop high purity drugs.</p>Formula:C26H24FNO5Purity:Min. 95%Molecular weight:449.47 g/molLansoprazole N-oxide
CAS:<p>Lansoprazole N-oxide is a prodrug that is converted to lansoprazole sulfone in vivo. Lansoprazole N-oxide is used as a diluent in chromatographic experiments. It has been shown to be more sensitive than the parent compound, lansoprazole, for the diagnosis of reflux oesophagitis. Lansoprazole N-oxide also has a validation wavelength of 240 nm and can be detected by liquid chromatography. The active form of lansoprazole, lansoprazole sulfone, can be detected by gas chromatography mass spectrometry (GCMS).</p>Formula:C16H14F3N3O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:385.36 g/mol2-Hydroxybenzimidazole
CAS:<p>2-Hydroxybenzimidazole is a benzimidazole compound that is used in the treatment of nervous system diseases. It has been shown to have anti-inflammatory properties and can be used in the treatment of syncytial virus infection. 2-Hydroxybenzimidazole inhibits the production of reactive oxygen species and nitric oxide, which are involved in neurodegenerative disorders. The mechanism of action for 2-Hydroxybenzimidazole involves the formation of hydrogen bonds with hydroxyl groups on proteins. It also has been shown to reduce locomotor activity and increase sleep time in mice, which may be due to inhibition of acetylcholine release from cholinergic neurons.</p>Formula:C7H6N2OPurity:Min. 97.5 Area-%Color and Shape:Off-White PowderMolecular weight:134.14 g/mol10,11-Dihydroxy-d10 Carbamazepine
Controlled Product<p>10,11-Dihydroxy-d10 Carbamazepine is a drug product that is used as an analytical reference standard. It is natural and synthetic impurity in the API (active pharmaceutical ingredient) Carbamazepine. The CAS number for 10,11-Dihydroxy-d10 Carbamazepine is 513-81-5. This compound has been synthesized by custom synthesis and is an impurity standard for HPLC analysis of carbamazepine. 10,11-Dihydroxy-d10 Carbamazepine is also a research and development chemical for the drug development industry. It has been classified as a niche chemical due to its high purity and pharmacopoeia grade.</p>Purity:Min. 95%2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole
CAS:<p>2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole is a protonated sulfonamide that is used as an analytical method to detect the presence of other drugs in human liver tissue. It has been shown to inhibit the activity of cytochrome P450 3A4 (CYP3A4), one of the enzymes responsible for metabolizing many drugs. Bromoenol lactone and powder diffraction spectrum are two additional analytical methods that can be used to detect 2-[([(4-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole.</p>Formula:C18H21N3O4SPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:375.44 g/mol(R)-5-Hydroxymethyl tolterodine
CAS:<p>(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed to</p>Formula:C22H31NO2Purity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:341.49 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole
CAS:<p>Omeprazole is a drug that belongs to the class of benzimidazole compounds. It is an inhibitor of gastric acid secretion in the stomach, reducing the production of hydrochloric acid and pepsin. Omeprazole has been shown to have greater chemical stability than other proton pump inhibitors (PPIs), with a higher solubility in water and a longer shelf life. Omeprazole also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Omeprazole also exhibits pharmacokinetic properties that are different from other PPIs. Omeprazole is rapidly absorbed following oral administration and has a high bioavailability, which can be attributed to its hydroxyl group. This hydroxyl group allows for esomeprazole (a prodrug) to be formed by hydrolysis in the gut or liver, increasing omeprazole's absorption and bioavailability.</p>Formula:C17H19N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:329.42 g/mol2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS:<p>Rabeprazole is a proton pump inhibitor that is used to treat acid-related disorders such as gastroesophageal reflux disease and peptic ulcers. Rabeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium ATPase that is found in the parietal cells of the stomach. The main mechanism of action for rabeprazole is competitive inhibition of the proton pump, which leads to decreased gastric acid secretion. Rabeprazole can be administered orally or intravenously, with a half-life of about 2 hours. It has been shown to have an effect on human liver cytochrome P450s, but does not affect the activity of recombinant cytochrome P450 3A4 (CYP3A4). In clinical studies, rabeprazole was shown to have no adverse effects on CYP3A4 activity and may even increase it slightly.</p>Formula:C18H21N3O2SPurity:Min. 95%Color and Shape:White PowderMolecular weight:343.44 g/molPantoprazole N-oxide sodium
CAS:<p>Pantoprazole N-oxide sodium is a custom synthesis drug product that is being developed as an impurity standard in the synthesis of Pantoprazole. The compound is also used as a pharmacopoeia analytical standard and a HPLC standard.</p>Formula:C16H15F2N3O5S·NaPurity:Min. 95%Color and Shape:PowderMolecular weight:422.36 g/molVarenicline
CAS:<p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.26(S)-tert-Butyl 2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS:Formula:C12H19N3O2Purity:98%Molecular weight:237.3036-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS:Formula:C13H16BClN2O2Purity:97%Molecular weight:278.54Methyl 1H-indazole-4-carboxylate
CAS:Formula:C9H8N2O2Purity:98%Color and Shape:SolidMolecular weight:176.1756-Fluoro-1-methyl-1H-benzo[d]imidazole
CAS:Formula:C8H7FN2Purity:98%Color and Shape:SolidMolecular weight:150.1565-Hydroxy-1H-benzo[d]imidazole-4-carboxylic acid
CAS:Formula:C8H6N2O3Purity:97%Molecular weight:178.1475-Methoxy-1-methyl-1H-benzo[d]imidazole
CAS:Formula:C9H10N2OPurity:98%Color and Shape:SolidMolecular weight:162.1924-(1H-IMIDAZOL-1-YLMETHYL)BENZOIC ACID
CAS:Formula:C11H10N2O2Purity:97%Color and Shape:SolidMolecular weight:202.213Ref: 10-F672798
1g797.00€5g2,158.00€10g3,200.00€2.5g1,461.00€50mg210.00€100mg299.00€250mg414.00€500mg633.00€5-Bromo-3-methyl-1H-indazole
CAS:Formula:C8H7BrN2Purity:97%Color and Shape:Solid, Pink powderMolecular weight:209.979(5-Methoxy-1H-benzoimidazol-2-yl)-methanol
CAS:Formula:C9H10N2O2Purity:97%Color and Shape:SolidMolecular weight:178.1911-(4-Fluorophenyl)imidazoline-2-thione
CAS:Formula:C9H7FN2SPurity:95.0%Color and Shape:SolidMolecular weight:194.233-Bromo-1H-indazole-7-carboxylic acid
CAS:Formula:C8H5BrN2O2Purity:95%Color and Shape:Liquid, No data available.Molecular weight:241.0441-Propyl-1H-benzoimidazol-2-ylamine
CAS:Formula:C10H13N3Purity:96%Color and Shape:SolidMolecular weight:175.2351H-BENZIMIDAZOLE-1-CARBOXYLIC ACID, 4-(BROMOMETHYL)-6-CHLORO-, 1,1-DIMETHYLETHYL ESTER
CAS:Purity:98%Molecular weight:345.61999511-[(4S)-4-(1-Methylethyl)-2-thioxo-3-oxazolidinyl]-1-propanone
CAS:Purity:98%Color and Shape:SolidMolecular weight:201.27999881-Methyl-1H-imidazole-4-carboxylic acid
CAS:Formula:C5H6N2O2Purity:98%Color and Shape:SolidMolecular weight:126.1155-Chloro-3-iodo-1H-indazole
CAS:Formula:C7H4ClIN2Purity:96%Color and Shape:SolidMolecular weight:277.911(R)-4-Formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester
CAS:Formula:C11H19NO4Purity:95%Color and Shape:LiquidMolecular weight:229.2764,5,6,7-TETRABROMO-N,N-DIMETHYL-1H-BENZO[D]IMIDAZOL-2-AMINE
CAS:Purity:98%Molecular weight:476.79199221H-Benzimadazole-5-carboxylic acid
CAS:Formula:C8H6N2O2Purity:95%Color and Shape:SolidMolecular weight:162.1482-CHLORO-1,3-BIS(2,6-DIISOPROPYLPHENYL)-1H-IMIDAZOL-3-IUM CHLORIDE
CAS:Purity:95%Color and Shape:SolidMolecular weight:459.53-Butyl-1-methyl-1H-imidazol-3-ium bromide
CAS:Formula:C8H15BrN2Purity:95%Color and Shape:Solid, Crystalline Powder or LumpsMolecular weight:219.126Methyl 2-bromo-4-oxazolecarboxylate
CAS:Formula:C5H4BrNO3Purity:95%Color and Shape:Liquid, No data available.Molecular weight:205.9951-(3-Aminopropyl)imidazole
CAS:Formula:C6H11N3Purity:97%Color and Shape:Liquid, Clear LiquidMolecular weight:125.175Ref: 10-F779467
1g524.00€5g1,350.00€10g2,024.00€25g4,650.00€100g16,290.00€2.5g987.00€100mg156.00€250mg224.00€500mg401.00€6-(Trifluoromethyl)-1H-indazole-3-carbaldehyde
CAS:Formula:C9H5F3N2OPurity:97%Color and Shape:SolidMolecular weight:214.1471-(1H-benzimidazol-2-yl)ethanone
CAS:Formula:C9H8N2OPurity:97%Color and Shape:SolidMolecular weight:160.1765-Amino-2-mercaptobenzimidazole
CAS:Formula:C7H7N3SPurity:98%Color and Shape:SolidMolecular weight:165.211H-Imidazole hydrochloride
CAS:Formula:C3H5ClN2Purity:95%Color and Shape:Solid, White to off-white crystalline powderMolecular weight:104.54tert-Butyl 6-bromo-4-methoxy-1H-indazole-1-carboxylate
CAS:Formula:C13H15BrN2O3Purity:97%Molecular weight:327.1781-Butyl-2,3-dimethyl-1H-imidazol-3-ium chloride
CAS:Formula:C9H17ClN2Purity:98%Color and Shape:Liquid, No data available.Molecular weight:188.74-Bromo-6-fluoro-1H-indazole
CAS:Formula:C7H4BrFN2Purity:95%Color and Shape:SolidMolecular weight:215.025
![5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIM57920.webp&w=3840&q=75)
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![6-(Trifluoromethyl)-1H-benzo[d]imidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF329414.webp&w=3840&q=75)
![6-Fluoro-1-methyl-1H-benzo[d]imidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF209049.webp&w=3840&q=75)
![5-Hydroxy-1H-benzo[d]imidazole-4-carboxylic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF546081.webp&w=3840&q=75)
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![2-((6-Methyl-1H-benzo[d]imidazol-2-yl)thio)propanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF754873.webp&w=3840&q=75)
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