Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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Cenicriviroc
CAS:<p>Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.</p>Formula:C41H52N4O4SPurity:97.87%Color and Shape:SolidMolecular weight:696.94Dotinurad
CAS:<p>Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).</p>Formula:C14H9Cl2NO4SPurity:97.43% - 98.04%Color and Shape:SolidMolecular weight:358.2Clomazone
CAS:<p>Clomazone, an herbicide, hinders chlorophyll production; it's a 2-chlorobenzyl and isoxazole compound.</p>Formula:C12H14ClNO2Purity:98.76% - 99.26%Color and Shape:SolidMolecular weight:239.7Simeprevir sodium
CAS:<p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>Formula:C38H46N5NaO7S2Purity:98%Color and Shape:SolidMolecular weight:771.92Benazepril EP Impurity F (Benazepril USP Related Compound F)
CAS:Formula:C16H22N2O3Molecular weight:290.37Baricitinib phosphate
CAS:<p>Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.</p>Formula:C16H20N7O6PSPurity:99.4% - 99.82%Color and Shape:SolidMolecular weight:469.41Indacaterol
CAS:<p>Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.</p>Formula:C24H28N2O3Purity:99.96%Color and Shape:SolidMolecular weight:392.49Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Formula:C22H28FN4O6PPurity:98.56%Color and Shape:SolidMolecular weight:494.45Ilaprazole
CAS:<p>Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.</p>Formula:C19H18N4O2SPurity:99.91%Color and Shape:SolidMolecular weight:366.44DNQX disodium salt
CAS:<p>DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptor</p>Formula:C8H2N4Na2O6Purity:98.93%Color and Shape:SolidMolecular weight:296.1Asciminib
CAS:<p>Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5–0.8nM).</p>Formula:C20H18ClF2N5O3Purity:98.82% - 99.70%Color and Shape:SolidMolecular weight:449.84Iproniazid
CAS:<p>Iproniazid is an irreversible monoamine oxidase inhibitor. It is used as an antidepressive agent.</p>Formula:C9H13N3OPurity:98%Color and Shape:SolidMolecular weight:179.22Azilsartan trimethylethanolamine
CAS:<p>Azilsartan, by Takeda, is an angiotensin II blocker used to treat hypertension.</p>Formula:C55H53N9O11Color and Shape:SolidMolecular weight:1016.081Solifenacin
CAS:Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,Formula:C23H26N2O2Purity:99.87%Color and Shape:SolidMolecular weight:362.46Cerdulatinib
CAS:<p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.54Bepridil hydrochloride
CAS:<p>Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels</p>Formula:C24H35ClN2OPurity:99.45% - 99.68%Color and Shape:SolidMolecular weight:403ABT530
CAS:<p>ABT530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6.</p>Formula:C57H65F5N10O8Purity:99.15% - 99.93%Color and Shape:SolidMolecular weight:1113.18Montelukast
CAS:<p>Montelukast (Singular), oral asthma med, linked to rare liver injury.</p>Formula:C35H36ClNO3SPurity:98.56% - >99.99%Color and Shape:SolidMolecular weight:586.18Betaxolol
CAS:<p>Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.</p>Formula:C18H29NO3Purity:99.01%Color and Shape:White Crystalline SolidMolecular weight:307.43Fasiglifam
CAS:<p>Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist.</p>Formula:C29H32O7SPurity:99.82% - 99.9%Color and Shape:SolidMolecular weight:524.63Pralsetinib
CAS:<p>Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T</p>Formula:C27H32FN9O2Purity:97.88% - 99.8%Color and Shape:SolidMolecular weight:533.6Tazarotene
CAS:<p>Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.</p>Formula:C21H21NO2SPurity:97.01% - 99.14%Color and Shape:White SolidMolecular weight:351.46Revefenacin
CAS:<p>Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.</p>Formula:C35H43N5O4Purity:98.12%Color and Shape:SolidMolecular weight:597.75Fenoprofen Calcium
CAS:<p>Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.</p>Formula:C30H26CaO6Purity:99.24% - 99.66%Color and Shape:SolidMolecular weight:522.6Torcetrapib
CAS:<p>Torcetrapib (CP-529414), a CETP inhibitor, curbs cholesteryl ester movement from HDL to LDL/VLDL; failed Phase III trials due to mortality increase.</p>Formula:C26H25F9N2O4Purity:98% - 99.59%Color and Shape:LipidMolecular weight:600.47Glycopyrrolate
CAS:<p>Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.</p>Formula:C19H28BrNO3Purity:99.41% - 99.64%Color and Shape:SolidMolecular weight:398.33GW280264X
CAS:<p>GW280264X (Carbamic acid) is an inhibitor of ADAM17 .</p>Formula:C28H41N5O6SPurity:99.51%Color and Shape:SolidMolecular weight:575.72Crizotinib
CAS:<p>Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.</p>Formula:C21H22Cl2FN5OPurity:99% - 99.87%Color and Shape:SolidMolecular weight:450.34Aprepitant
CAS:<p>Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist.</p>Formula:C23H21F7N4O3Purity:98% - 99.68%Color and Shape:Off-White To Light Yellow Cyrstalline SolidMolecular weight:534.43Binimetinib
CAS:<p>Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C17H15BrF2N4O3Purity:98.03% - >99.99%Color and Shape:SolidMolecular weight:441.23Zaltoprofen
CAS:<p>Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.</p>Formula:C17H14O3SPurity:99.72%Color and Shape:Off-White To Pale Yellow Crystalline SolidMolecular weight:298.36Tianeptine sodium salt
CAS:<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Formula:C21H24ClN2NaO4SPurity:99.82%Color and Shape:SolidMolecular weight:458.93Alobresib
CAS:<p>Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.</p>Formula:C26H23N5O2Purity:97.63%Color and Shape:SolidMolecular weight:437.49Varenicline dihydrochloride
CAS:<p>Varenicline dihydrochloride is a Selective α4β2 nicotinic acetylcholine receptor partial agonist.</p>Formula:C13H15Cl2N3Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:284.18Alectinib
CAS:<p>Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C30H34N4O2Purity:98% - 99.38%Color and Shape:SolidMolecular weight:482.62Isoxsuprine Free Base
CAS:<p>Isoxsuprine Free Base relaxes uterine/vascular muscles, dilates arteries, treats peripheral vascular disease, and premature labor.</p>Formula:C18H23NO3Color and Shape:SolidMolecular weight:301.38Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61Dofetilide
CAS:<p>Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.</p>Formula:C19H27N3O5S2Purity:97.85% - 99.06%Color and Shape:Off-White Or Yellowish Crystalline PowderMolecular weight:441.56Lercanidipine hydrochloride
CAS:<p>Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.</p>Formula:C36H41N3O6·HClPurity:99.86% - 99.91%Color and Shape:Pale-Yellow PowderMolecular weight:648.19Ivabradine hydrochloride
CAS:<p>Ivabradine HCl (S 16257-2) is an If inhibitor (IC50: 2.9 μM) and SA node HCN channel blocker that slows heart rate.</p>Formula:C27H37ClN2O5Purity:99% - 99.73%Color and Shape:SolidMolecular weight:505.05Fosaprepitant dimeglumine
CAS:<p>Fosaprepitant dimeglumine (MK-0517) is a soluble prodrug of aprepitant, which prevents nausea by blocking NK1 receptors.</p>Formula:C37H56F7N6O16PPurity:98% - 99.03%Color and Shape:SolidMolecular weight:1004.83JNJ-31020028
CAS:<p>JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity (pIC50=8.07, human; pIC50=8.22, rat).</p>Formula:C34H36FN5O2Purity:95.92% - 99.65%Color and Shape:SolidMolecular weight:565.68Pyraclostrobin
CAS:<p>Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.</p>Formula:C19H18ClN3O4Purity:99.89%Color and Shape:SolidMolecular weight:387.82Perospirone
CAS:<p>Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors.</p>Formula:C23H30N4O2SPurity:99.23%Color and Shape:White PowderMolecular weight:426.57Flumatinib mesylate
CAS:<p>Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.</p>Formula:C30H33F3N8O4SPurity:99.82%Color and Shape:SolidMolecular weight:658.69Enalapril Maleate
CAS:<p>Enalapril Maleate (MK-421 Maleate), an ACE inhibitor, is utilized in the treatment of hypertension, chronic heart failure, and diabetic nephropathy.</p>Formula:C20H28N2O5·C4H4O4Purity:99.02% - ≥95%Color and Shape:White To Off-White Crystalline Powder SolidMolecular weight:492.52Bepotastine Besilate
CAS:<p>Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).</p>Formula:C21H25ClN2O3·C6H6O3SPurity:99.83% - 99.9%Color and Shape:Brown Viscous LiquidMolecular weight:547.06Maraviroc
CAS:<p>Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.</p>Formula:C29H41F2N5OPurity:97.13% - 99.59%Color and Shape:Brown SolidMolecular weight:513.67Melitracen hydrochloride
CAS:Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Formula:C21H26ClNPurity:99.99%Color and Shape:Crystalline SolidMolecular weight:327.90Filgotinib
CAS:<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.5Benzyl butyl phthalate
CAS:<p>Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.</p>Formula:C19H20O4Purity:99.02%Color and Shape:Colourless Liquid Oily LiquidMolecular weight:312.363,4-Dimethoxybenzamide
CAS:<p>3,4-Dimethoxybenzamide from Streptoverticillium morookaense is used to synthesize Itopride hydrochloride.</p>Formula:C9H11NO3Purity:99.5%Color and Shape:SolidMolecular weight:181.19Flupirtine
CAS:<p>Flupirtine(D 9998) is a selective neuronal potassium channel opener as well as shows properties of NMDA receptor antagonist.</p>Formula:C15H17FN4O2Color and Shape:SolidMolecular weight:304.32Isopropamide Iodide
CAS:<p>Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.</p>Formula:C23H33IN2OPurity:99.67%Color and Shape:SolidMolecular weight:480.43Bepotastine
CAS:<p>Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis.</p>Formula:C21H25ClN2O3Purity:99.75%Color and Shape:SolidMolecular weight:388.89Benzetimide hydrochloride
CAS:<p>Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.</p>Formula:C23H27ClN2O2Purity:99.32%Color and Shape:Off-White PowderMolecular weight:398.93
