Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65615 products of "Quinazoline and Quinoline Derivatives"
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(R,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
CAS:Purity:99.0%Molecular weight:485.94000244140625(R)-1-(2-Bromopyridin-4-yl)ethanamine dihydrochloride
CAS:Purity:97.0%Molecular weight:273.9800109863281Terfenadine
CAS:Controlled Product<p>Applications Nonsedating-type histamine H1-receptor antagonist. Antihistaminic.<br>References Carr, A.A., et al.: Arzneim. Forsch., 32, 1157 (1982), Badwan, A.A., et al.: Anal. Profiles Drug Subs., 19, 627 (1990), Masheter, H.C., et al.: Clin. Rev. Allergy, 11, 5 (1993), Jurima-Romet, M., et al.: Drug Metab. Dispos., 22, 849 (1994),<br></p>Formula:C32H41NO2Color and Shape:White To Off-WhiteMolecular weight:471.674-phenyl-3-(2-thienyl)-1,2,4-triazoline-5-thione 98%
CAS:Purity:98.0%Molecular weight:259.3500061035156Relcovaptan
CAS:<p>Stability Hygroscopic<br>Applications Relcovaptan is a selective vasopressin-1a receptor antagonist that prevents cellular swelling and provides treatment for post-traumatic brain edema.<br>References Marmarou, C.R., et. al.: Brain Res., 1581, 89 (2014)<br></p>Formula:C28H27Cl2N3O7SColor and Shape:NeatMolecular weight:620.503-Chloro-4-(3-fluorobenzyloxy)aniline
CAS:<p>Applications 3-Chloro-4-(3-fluorobenzyloxy)aniline is an intermediate in the synthesis of Lapatinib (L175800).<br>References Petrov, K., et al.: Bioorg. Med. Chem. Lett., 16, 4686 (2006),<br></p>Formula:C13H11ClFNOColor and Shape:BrownMolecular weight:251.68rac trans-Loxoprofen Alcohol
CAS:<p>Applications The cis-alcohol metabolite of Loxoprofen (L472900).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Terada, A., et al.: J. Med. Chem., 27, 212 (1984), Sugimoto, M., et al.: Biochem. Pharmacol., 42, 2363 (1991), Riendeau, D., et al.: Bioorg. Med. Chem. Lett., 14, 1201 (2004),<br></p>Formula:C15H20O3Color and Shape:NeatMolecular weight:248.324-Methoxy-2-(((5-methoxy-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,5-dimethylpyridine 1-oxide
CAS:Purity:95.0%Molecular weight:361.42001342773441-Phenyl-2-pyrazin-2-yl ethanone
CAS:Formula:C12H10N2OPurity:95.0%Color and Shape:SolidMolecular weight:198.2257-Hydroxy-4-(3-pyridyl)coumarin
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:239.229995727539065-(1,3-Dioxolan-2-yl)-2-(4-nitrobenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:305.2999877929687510H-Phenothiazine
CAS:Purity:95.0%Color and Shape:Solid, Crystalline Powder or Flakes or Pellets or PowderMolecular weight:199.27000427246094Teneligliptin
CAS:<p>Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.</p>Formula:C22H30N6OSPurity:99.73%Color and Shape:SolidMolecular weight:426.581-Chloro-2-nitrobenzene
CAS:Controlled Product<p>Applications 1-Chloro-2-nitrobenzene is a useful synthetic intermediate. It was used in the synthesis of 1-hydroxybenzotriazole derivatives. Reaction of 1-chloro-2-nitrobenzene with dinitrogen pentoxide in dichloromethane is strongly catalysed by H-Faujasite-720.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fathalla, M., et al.: J. Chem. Soc. Pak., 33, 324 (2011); Claridge, R., et al.: J. Chem. Soc. Perkin Trans. II, 9, 1815, (1999)<br></p>Formula:C6H4ClNO2Color and Shape:NeatMolecular weight:157.552-(Chloromethyl)-6-methoxypyridine
CAS:Formula:C7H8ClNOPurity:95.0%Color and Shape:LiquidMolecular weight:157.6Desmethyl Ofloxacin
CAS:Controlled Product<p>Impurity Ofloxacin EP Impurity E<br>Applications Desmethyl Ofloxacin (Ofloxacin EP Impurity E) is a metabolite of Ofoxacin (O245750), a fluorinated quinolone antibacterial.<br>References Leysen, D., et al.: Antimicrob. Agents Chemother., 33, 1 (1989); Polk, R., et al.: J. Antimicrob. Chemother., 27, 17 (1991); Todo, Y., et al.: Chem. Pharm. Bull., 42, 2049 (1994); Furuhata, K., et al.: Biol. Pharm. Bull., 21, 456 (1998); Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Formula:C17H18FN3O4Color and Shape:White To Light BeigeMolecular weight:347.34N-Nitroso Iminostilbene
CAS:Controlled Product<p>Applications N-Nitroso Iminostilbene is derived from Iminostilbene (I445000), which is a metabolite of Carbamazepine (CBZ) (C175840).<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001)<br></p>Formula:C14H10N2OColor and Shape:NeatMolecular weight:222.242,6-Dimethoxypyridine-3,5-diamine hydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:205.639999389648443-[(pyridin-3-ylamino)carbonyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS:Purity:95.0%Molecular weight:258.27700805664061-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:295.242004394531252-(5-Amino-3-phenylpyrazol-1-yl)ethanol
CAS:Purity:95.0%Color and Shape:Solid, Off-white solidMolecular weight:203.24499511718756-Methyl-2-pyridin-4-yl-quinoline-4-carboxylic acid
CAS:Purity:90.0%Molecular weight:264.28399658203125N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-chloromethyl Benzamide
CAS:Controlled Product<p>Applications Gleevec Impurity<br></p>Formula:C24H20ClN5OColor and Shape:Off WhiteMolecular weight:429.901,1-Cyclohexanediacetic Acid
CAS:<p>Applications 1,1-Cyclohexanediacetic Acid (cas# 4355-11-7) is a compound useful in organic synthesis.<br></p>Formula:C10H16O4Color and Shape:NeatMolecular weight:200.23Desfluoro Risperidone
CAS:Controlled Product<p>Impurity Risperidone EP Impurity K<br>Applications Desfluoro Risperidone (Risperidone EP Impurity K) is a Risperidone (R525000) impurity, as antipsychotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C23H28N4O2Color and Shape:NeatMolecular weight:392.49Thioridazine-d3 Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Dopamine receptor blocker; parent compound of sulforidazine and mesoridazine. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Formula:C21D3H23N2S2·ClHColor and Shape:NeatMolecular weight:410.05Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:330.36300659179692'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4 is the isotope labelled analog of 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid (T308515); a transformation product of Valsartan (V095750) which is a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid.<br>References Noedler, K., et al.: Water Res., 47, 6650 (2013); Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Formula:C14H6D4N4O2Color and Shape:NeatMolecular weight:270.28(Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid is a stereoisomer of Epalrestat (E565300), an aldose reductase inhibitor. Used in the treatment of diabetic neuropathy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Terashima, H., et al.: J. Pharmacol. Exp. Ther., 229, 226 (1983), Kikkawa, R., et al.: Diabetologia, 24, 290 (1983), Kojima, K., et al.: Jpn. J. Ophthalmol., 29, 99 (1985), Qi, M. et al.: J. Beij, Inst. Tech., 13, 445 (2004);<br></p>Formula:C15H13NO3S2Color and Shape:Yellow-Red SolidMolecular weight:319.42-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol Hemisulfate Hydrate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol Hemisulfate Hydrate is a salt form of 2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-isoquinolinetriol (CAS 94120-05-5) which is used in analytical study of identification of degradation products and process impurities from terbutaline sulfate by UHPLC-Q-TOF-MS/MS and In silico toxicity prediction.<br>References Zhou, N., et al.: Chromatographia, 80, 793 (2017)<br></p>Formula:(C13H19NO3)•H2SO4•x(H2O)Color and Shape:NeatMolecular weight:2237.30980718024-Methyl-2-(4-methyl-2-pyridinyl)-1-(2-oxo-2-phenylethyl)pyridinium bromide
Molecular weight:383.28900146484375Potassium Phthalimide
CAS:Controlled Product<p>Applications Potassium Phthalimide is a green, solid-base organocatalys.<br>References Kiyani, H., Ghiasi, M.: Chinese Chem. Lett., 25, 313 (2014)<br></p>Formula:C8H4NO2·KColor and Shape:NeatMolecular weight:185.222-(1-phenyl-1H-pyrazol-4-yl)cyclopropane-1-carboxylic acid
CAS:Purity:95.0%Molecular weight:228.251007080078122-(1-Nitroso-4-piperidinyl)-1H-benzimidazole
CAS:Controlled ProductFormula:C12H14N4OColor and Shape:NeatMolecular weight:230.266(S)-(-)-4’-Hydroxyphenyl Carvedilol
CAS:Controlled Product<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formula:C24H26N2O5Color and Shape:NeatMolecular weight:422.47Urapidil Hydrochloride
CAS:<p>Applications α1-Adrenergic antagonist; derivative of Uracil (U801000). Antihypertensive.<br>References Eltze, M., et al.: Eur. J. Pharmacol., 59, 1 (1979), Barankay, A., et al.: Arzneim.-Forsch., 31, 849 (1981), Belz, G.G., et al.: Clin. Pharmacol. Ther., 37, 48 (1985),<br></p>Formula:C20H29N5O3·ClHColor and Shape:NeatMolecular weight:423.94Terbufoxon Sulfoxide
CAS:Controlled Product<p>Applications Terbufoxon Sulfoxide is a metabolite of Terbufoxon (T109075), a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rahman, Md. M. et al.: Food Chem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008); Polgar, L. et al.: J. Chrom. A., 1249, 83 (2012);<br></p>Formula:C9H21O4PS2Color and Shape:NeatMolecular weight:288.368-chloro-2-(2-methylphenyl)quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:297.7399902343755-BENZYLOXY-2-(5-CHLORO-PYRIDIN-3-YL)-4-METHOXY-PYRIMIDINE
CAS:Purity:95.0%Molecular weight:327.7699890136719L-Kynurenine-d4 [4-(2-aminophenyl-3,5-d2); 3,3-d2]
CAS:Controlled Product<p>Applications L-Kynurenine-d4 [4-(2-aminophenyl-3,5-d2); 3,3-d2] is a useful isotopically labeled compound of L-Kynurenine (K661005)<br></p>Formula:C10D4H8N2O3Color and Shape:NeatMolecular weight:212.24Iso Sildenafil
CAS:Controlled Product<p>Applications Iso Sildenafil is the isomer of Sildenafil methylated at N-2 position of the pyrazolo[4,3-d]pyrimidin-7-one nucleus.<br>References Sheldrick, G., et al.: Acta Crystallogr., A46, 467 (1990), Terrett, N., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996),<br></p>Formula:C22H30N6O4SColor and Shape:NeatMolecular weight:474.582-(4-t-Butylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Purity:97.0%Molecular weight:316.42001342773442-Chloro-5-fluoroquinoline
CAS:Formula:C9H5ClFNPurity:95%Color and Shape:SolidMolecular weight:181.592-Amino-4-thiazoleacetic Acid
CAS:Controlled ProductFormula:C5H6N2O2SColor and Shape:NeatMolecular weight:158.18Meclizine
CAS:<p>Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptors</p>Formula:C25H27ClN2Purity:99.55%Color and Shape:SolidMolecular weight:390.95Tolcapone-d4
CAS:Controlled Product<p>Applications Orally active inhibitor of central and peripheral catechol-O-methyltransferase (COMT). Antiparkinsonian.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dingemanse, J., et al.: Clin. Pharmacol. Ther., 57, 508 (1995), Keating, K.A., Drugs, 19, 165 (2005),<br></p>Formula:C14H7D4NO5Color and Shape:NeatMolecular weight:277.27Levomepromazine EP Impurity D
Controlled ProductFormula:C32H33N3O2S2Color and Shape:NeatMolecular weight:555.86-Methyl-5-((3-(2-(methylthio)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-amine
CAS:Purity:98%Molecular weight:374.45999145507811-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS:<p>Applications Used in the preparation of Mirtazapine (M365000) impurities.<br></p>Formula:C17H18N4Color and Shape:Light Yellow To BrownMolecular weight:278.351-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,6-diol
CAS:Controlled Product<p>Applications 1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine.<br>References Dousa, M. et al.: J. Pharm. Biomed. Anal., 55, 949 (2011);<br></p>Formula:C15H17NO4Color and Shape:NeatMolecular weight:275.302-[2-(Pyridin-4-yl)thiazol-4-yl]acetic acid
CAS:Formula:C10H8N2O2SColor and Shape:SolidMolecular weight:220.25(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin (V305000).<br>References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008);<br></p>Formula:C7H9ClN2OColor and Shape:NeatMolecular weight:172.61Moclobemide
CAS:Controlled Product<p>Applications A reversible monoamine oxidase inhibitor.<br>References Wiesel, F.A., et al.: Eur. J. Clin. Pharmacol., 28, 89 (1985), Burkard, W.P., et al.: J. Pharmacol. Exp. Ther., 248, 391 (1989)<br></p>Formula:C13H17ClN2O2Color and Shape:WhiteMolecular weight:268.746-Oxo-1-[4-(trifluoromethyl)benzyl]-1,6-dihydro-3-pyridinecarboxylic acid
CAS:Formula:C14H10F3NO3Color and Shape:SolidMolecular weight:297.233(4-Bromo-5-cyclopropyl-3-trifluoromethyl-pyrazol-1-yl)-acetic acid
CAS:Formula:C9H8BrF3N2O2Purity:95.0%Color and Shape:SolidMolecular weight:313.074(S)-Naproxen Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Naproxen.<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Jin, C., et al.: J. Pharmacol. Exp. Ther., 264, 475 (1993),King, C., et al.: Toxicol. Sci., 61, 49 (2001), Aresta, A., et al.: J. Pharm. Biomed. Anal., 39, 643 (2005),<br></p>Formula:C20H22O9Color and Shape:NeatMolecular weight:406.38(±)-Mianserin-d3 Hydrochloride (methyl-d3)
CAS:Controlled Product<p>Applications (±)-Mianserin-d3 HCl (methyl-d3) (CAS# 1219804-97-3) is a useful isotopically labeled research compound.<br></p>Formula:C18D3H17N2·ClHColor and Shape:NeatMolecular weight:303.8442Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)
CAS:Controlled Product<p>Impurity Levofloxacin USP Related Compound B<br>Applications Levofloxacin intermediate.<br>References Liu, Bo; Y., et al.: Bioorg. Med. Chem., 13, 2451 (2005), Lalitha D., et al.: J. Pharm. Biomed. Anal., 50, 710 (2009),<br></p>Formula:C13H9F2NO4Color and Shape:NeatMolecular weight:281.21Tazarotene
CAS:<p>Applications An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Formula:C21H21NO2SColor and Shape:Light YellowMolecular weight:351.461-(4-Chlorophenyl)-5-[6-[[4-[(4-chlorophenyl)amino]-6-[(1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl]-1,3,5-triazin-2-yl]amino]hexyl]biguanide D-Gluconic Acid
CAS:Controlled ProductFormula:C28H38Cl2N10O5•C6H12O7Color and Shape:NeatMolecular weight:665.5719616rac Phenylephrine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Phenylephrine is a selective α1-adrenergic receptor agonist used as a decongestant. Phenylephrine lowers intraocular pressure and is used as an agent to dilate the pupil.<br>References Lorenzetti, O.J. et al.: Exp. Eye Res., 12, 80 (1971); Ando, J. et al.: Nip. Yakur. Zas., 61, 471 (1965);<br></p>Formula:C9H14ClNO2Color and Shape:NeatMolecular weight:203.676-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one
CAS:Purity:98.0%Molecular weight:475.8500061035156Ref: 10-F549703
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire4’-O-Benzyloxy Ezetimibe
CAS:Controlled Product<p>Impurity Ezetimibe Benzyl Ether Impurity<br>Applications Protected Ezetimibe, used for the synthesis of related derivatives.<br>References Raman, B., et al.: J. Pharm. Biomed. Anal., 52, 73 (2010),<br></p>Formula:C31H27F2NO3Color and Shape:NeatMolecular weight:499.55N-Desmethyl Diphenhydramine Hydrochloride
CAS:<p>Applications N-Desmethyl Diphenhydramine is an impurity of Diphenhydramine (D486900) with antihistaminic activity.<br>References Nauta, W. T. et al.: Med. Chem., Spec. Contrib. Int. Symp., 3rd, 125 (1973);<br></p>Formula:C16H19NO·ClHColor and Shape:White To Light BeigeMolecular weight:277.79Vildagliptin-13C5,15N
CAS:Controlled ProductFormula:C1213C5H25N215NO2Color and Shape:NeatMolecular weight:309.362-{4-[4-(7-Hydroxy-naphthalen-1-yl)-piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione
Purity:95.0%Molecular weight:409.489990234375Iso Loratadine
CAS:Controlled Product<p>Impurity Loratadine EP Impurity E<br>Applications Iso Loratadine (Loratadine EP Impurity E) is a Loratadine (L469575) impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.<br>References Billah., et al.: Lipids, 26, 1172 (1991), Piwinski., et al.: J. Med. Chem., 34, 457 (1991),<br></p>Formula:C22H23ClN2O2Color and Shape:NeatMolecular weight:382.88Minoxidil Sulfate-d10
CAS:Controlled Product<p>Stability Light Sensitive - Protect from Light, Store in Freezer<br>Applications Labelled Minoxidil sulfate (M345100). Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14µM) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.<br>References Nakaya, Y., et al.: J. Dermatol. Sci., 7 (Suppl.), S104-S108 (1994), Ohtsuyama, M., et al.: J. Pharmacol. Exp. Ther., 269(2), 823 (1994), Andersson, K.E., et al.: Pharmacol. Toxicol., 70, 244 (1992), Bray, K.M., et al.: J. Biol. Chem., 267, 11689 (1992), Saitoh, M. et al.: Biochem. Biophys. Res. Commun., 140, 280 (1986)<br></p>Formula:C9H5D10N5O4SColor and Shape:NeatMolecular weight:299.371-Methyl-2-morpholin-4-yl-ethylamine
CAS:Formula:C7H16N2OPurity:95.0%Color and Shape:LiquidMolecular weight:144.218(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
CAS:<p>Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists such as Ticagrelor (T437700)for the prevention of thrombosis.<br>References Springthorpe, B. et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007);<br></p>Formula:C9H9F2N·C8H8O3Color and Shape:NeatMolecular weight:321.32cis-ent-Tadalafil
CAS:Controlled Product<p>Impurity Tadalafil EP Impurity C<br>Applications The (6S)-cis-enantiomer of Tadalafil (T004500). Tadalafil Impurity (6S,12aR)<br>References Aldridge, J., et al.: Br. Med. J., 318, 669 (1999), Daugan, A., et al.: J. Med. Chem., 46, 4533 (2003), Vredenbregt, M., et al.: J. Pharm. Biomed. Anal., 40, 840 (2006),<br></p>Formula:C22H19N3O4Color and Shape:White To Off-WhiteMolecular weight:389.40rac-Ruxolitinib-d9 (major)
CAS:Controlled Product<p>Applications Labelled racemic analogue of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.<br>References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);<br></p>Formula:C17H9D9N6Color and Shape:White To Light YellowMolecular weight:315.42Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride (90%)
CAS:<p>Applications Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride is an impurity of Imatinib Mesylate (G407000), a tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.<br>References Schindler, T., et al.: Science, 289, 1938 (2000); Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001)<br></p>Formula:C53H51ClN12O2Purity:90%Color and Shape:NeatMolecular weight:923.54-Amino-2,3,6-trifluoropyridine
CAS:Formula:C5H3F3N2Purity:95.0%Color and Shape:SolidMolecular weight:148.0885-chloro-4-methyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:289.7799987792969Prothioconazole
CAS:<p>Applications Prothioconazole is an antifungal metabolite used in agricultural fungicides and herbicides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aristimuno Ficoseco, M.E., et al.: Nat. Prod. Res (2016);<br></p>Formula:C14H15Cl2N3OSColor and Shape:NeatMolecular weight:344.26Bis-[Des(5-Chloro-2-carboxythienyl)] Rivaroxaban Phthalamide
CAS:Controlled ProductFormula:C36H36N6O10Color and Shape:NeatMolecular weight:712.71ETHYL 1-CYCLOPROPYL-6,7-DIFLUORO-8-METHOXY-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLATE
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:323.29598999023442-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4,6-diphenyl-1,3,5-triazine
CAS:Purity:95%Molecular weight:419.9100036621094Saccharin N-(2-Acetic Acid Isopropyl Ester)(Piroxicam Impurity F)
CAS:Controlled Product<p>Impurity Piroxicam EP Impurity F<br>Applications Piroxicam impurity F.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Formula:C12H13NO5SColor and Shape:NeatMolecular weight:283.30
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