Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65497 products of "Quinazoline and Quinoline Derivatives"
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Vadadustat
CAS:<p>Applications Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.<br>References Pergola, P., et al.: Kidney Int., 90, 1115 (2016);<br></p>Formula:C14H11ClN2O4Color and Shape:BeigeMolecular weight:306.703-Dehydroxy Salbutamol
CAS:Controlled Product<p>Impurity Levalbuterol USP Related Compound B; Salbutamol EP Impurity C<br>Applications 3-Dehydroxy Salbutamol (Levalbuterol USP Related Compound B; Salbutamol EP Impurity C) is an isoprenaline based selective stimulants of β-adrenergic receptors in bronchial muscles.<br>References Hartley, D., et al.: Nature., 219, 5156 (1968);<br></p>Formula:C13H21NO2Color and Shape:NeatMolecular weight:223.313-(3,4-dimethylphenyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one
CAS:Purity:98%Molecular weight:282.3599853515625Lansoprazole
CAS:<p>Applications Used as a gastric proton pump inhibitor. An antiulcerative. May limit the severity of tuberculosis (see Chem. and Eng. News. p. 28 July 20 (2018)).<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006), Chem. and Eng. News. p. 28 July 20 (2018)<br></p>Formula:C16H14F3N3O2SColor and Shape:White To Light BeigeMolecular weight:369.365-Aminoimidazole-4-carboxamide Lactose Adduct
Controlled Product<p>Stability Hygroscopic<br>Applications 5-Aminoimidazole-4-carboxamide Lactose Adduct is a lactose adduct of 5-Aminoimidazole-4-carboxamide (A611690), a metabolite of Temozolomide (T017775).<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999)<br></p>Formula:C16H26N4O11Color and Shape:NeatMolecular weight:450.44-Cyanopyridine
CAS:Controlled Product<p>Applications 4-Cyanopyridine is a reagent for the synthesis of 1-tolyl-5-benzylthiotetrazole and 2-hexylthio-4-pyridinecarbonitrile, an antituberculotics. Preparation of the antihypertensive agent Pinacidil using the chemoselective and green oxidative rearrangement of an amidine and addition of an amine to a guanidine as the key step. Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Human L-xylulose reductase (XR) is an enzyme of the glucuronic acid/uronate cycle of glucose metabolism with the possible target for treatment of the long-term complications of diabetes.<br>References Waisser, K., et al.: Folia Pharmaceutica Universitatis Carolinae, 18, 31 (1995); Carbone, V., et al.: Bioorg. Med. Chem., 13, 301 (2004); Baeten, M., et al.: Adv. Synth. Catal., 358, 826 (2016)<br></p>Formula:C6H4N2Color and Shape:WhiteMolecular weight:104.11Methyl 2-Methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate
CAS:<p>Applications Methyl 2-Methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate is a nicardipine impurity. Also, it is derived from Methyl Acetoacetate (O848425), which is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Vaghela, B. K., et al.: J. Liq. Chromatogr. Related Technol., 36, 2166-2181 (2013);<br></p>Formula:C15H15NO5·C16H17NO5Color and Shape:NeatMolecular weight:592.59Ticagrelor Epimer
Controlled Product<p>Applications Ticagrelor Epimer is an epimer impurity of Ticagrelor (T437700). Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Formula:C23H28F2N6O4SColor and Shape:NeatMolecular weight:522.576-chloro-4-methyl-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:289.7799987792969Afatinib-d6
CAS:Controlled ProductFormula:C24H19D6ClFN5O3Color and Shape:Light Yellow SolidMolecular weight:491.98rac-Hesperetin 7-O-Sulfate Sodium Salt
CAS:<p>Applications rac-Hesperetin 7-O-Sulfate Sodium Salt is a metabolite of rac-Hesperetin (H289501); a derivative of Hesperidine (H281185) with potential antihyperglycemic activity.<br>References Zhang, B., et al.: Bioorg. Med. Chem. Lett., 22, 7194 (2012)<br></p>Formula:C16H13NaO9SColor and Shape:NeatMolecular weight:404.326-Allyl-8b-carboxyergoline
CAS:<p>Impurity Cabergoline EP Impurity A<br>Applications 6-Allyl-8β-carboxyergoline is a metabolite of cabergoline (C050000) which is a dopamine D2-receptor agonist.<br>References Brambilla, E., et al.: Eur. J. Med. Chem., 24, 421 (1989), Ferrari, C., et al.: J. Clin. Endocrinol. Metab., 68, 1201 (1989), Hutton, J.T., et al.: Neurology, 46, 1062 (1996)<br></p>Formula:C18H20N2O2Color and Shape:Light Beige SolidMolecular weight:296.3636(4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
CAS:Controlled Product<p>Applications A HMG-CoA reductase inhibitor intermediate.<br>References Hummel, W., et al.: J. Microbiol. Methods, 9, 201 (1989), Jendralla, H., et al.: J. Med. Chem., 34, 2962 (1991), Vicenzi, J., et al.: Enzyme Microb. Technol., 20, 494 ( 1997),<br></p>Formula:C13H23ClO4Color and Shape:NeatMolecular weight:278.77Etoricoxib
CAS:Controlled ProductFormula:C18H15ClN2O2SColor and Shape:Off-WhiteMolecular weight:358.84Tebufenozide
CAS:Controlled Product<p>Applications Tebufenozide is a synthetic nonsteroidal ecdysone agonist used in pesticide formulations (1) that causes premature molting; novel insect growth regulator (2,3,4) specific to lepidopteran species. Drinking water Contaminant Candidate List 3 (CCL3) as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Jordan T, et al.: Anal Bioanal Chem. 2009 Aug;394(8):2257-66 2. Vianna U. Et al.: Ecotoxicology. 2009 Feb;18(2):180-6. 3. Rose, G. et al. Food. Chem. 2009 Dec;117(4) pp634-6404. Wang, J. et al.: J. Agric. Food Chem. 2009 Mar 25;57(6):2162-73.<br></p>Formula:C22H28N2O2Color and Shape:Off-WhiteMolecular weight:352.47MDV 3100 (Enzalutamide)
CAS:Controlled Product<p>Applications MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.<br>References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011);<br></p>Formula:C21H16F4N4O2SColor and Shape:WhiteMolecular weight:464.44N-(5-IODO-PYRIDIN-2-YL)-4-METHYL-BENZENESULFONAMIDE
CAS:Purity:95.0%Molecular weight:374.200012207031255-(4-CYCLOPROPYL-4H-1,2,4-TRIAZOL-3-YL)THIOPHEN-3-AMINE
CAS:Purity:95.0%Molecular weight:206.270004272460944-Hydroxy Omeprazole Preparation Kit
CAS:Controlled ProductFormula:C16H17N3O3SColor and Shape:Off White SolidMolecular weight:331.391-Phenyl-2-pyrazin-2-yl ethanol
CAS:Formula:C12H12N2OPurity:95.0%Color and Shape:SolidMolecular weight:200.2413-Ethyl-2-imine Meloxicam
CAS:Controlled Product<p>Applications Meloxicam (M216100) impurity.<br></p>Formula:C16H17N3O4S2Color and Shape:Light YellowMolecular weight:379.45Nitisinone
CAS:<p>Applications Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.<br>References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),<br></p>Formula:C14H10F3NO5Color and Shape:NeatMolecular weight:329.23Oxcarbazepine-D4 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.Only available as a mixture of deuterated material:d-1: 1%d-2: 9%d-3: 35%d-4: 55%<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),<br></p>Formula:C152H4H8N2O2Color and Shape:Light Orange Colour PowderMolecular weight:256.29Famotidine Amide Impurity Hydrochloride
CAS:<p>Applications Famotidine impurity.<br>References Junnarkar, G., et al.: Pharm. Res., 12, 599 (1995), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Formula:C8H14ClN5OS2Color and Shape:White SolidMolecular weight:295.81Risperidone Z-Oxime Impurity
CAS:Controlled Product<p>Impurity Risperidone EP Impurity B<br>Applications Risperidone Z-Oxime (Risperidone EP Impurity B) is an impurity of Risperidone (R525000). Risperidone impurity per USP.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Formula:C23H28F2N4O2Color and Shape:NeatMolecular weight:430.49Retigabine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A new experimental anticonvulsant drug. Anxiolytic.<br>References Dailey, J.W.; et al.: Neuroscience Lett., 195, 77 (1995), Korsgaard, M.P.G., et al.: J. Pharmacol. Exp. Ther., 314, 1, 282 (2005),<br></p>Formula:C16H18FN3O2Color and Shape:NeatMolecular weight:303.33N-Nitroso Clonidine
CAS:Controlled ProductFormula:C9H8Cl2N4OColor and Shape:NeatMolecular weight:259.09Raltegravir β-D-Glucuronide
CAS:<p>Applications A metabolite of Raltegravir.<br>References Bosma, P., et al.: J. Biol. Chem., 269, 17960 (1994), Richman, D., et al.: Nature, 410, 995 (2001), Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (2004), Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (2006),<br></p>Formula:C26H29FN6O11Color and Shape:NeatMolecular weight:620.54(6-Trifluoromethyl-pyridin-3-yl)-carbamic acid tert-butyl ester
CAS:Purity:95.0%Molecular weight:262.231994628906254-[2-(4-quinolinyl)vinyl]phenol
CAS:Purity:95.0%Color and Shape:Solid, Yellow powderMolecular weight:247.2969970703125Bunitrolol
CAS:<p>Applications Bunitrolol is a beta adrenoceptor antagonist that is used as an antihypertensive and antianginal agent.<br>References Narimatsu, S., et al.: Chirality, 11, 1 (1999); Tsuchihashi, H., et al.: Jpn. J. Pharmacol., 45, 349 (1987)<br></p>Formula:C14H20N2O2Color and Shape:Colourless To Light YellowMolecular weight:248.324,5-Desisopropylidene Topiramate
CAS:Controlled Product<p>Impurity Topiramate Impurity B<br>Applications A metabolite of Topiramate.<br>References Maryanoff, B., et al.: J. Med. Chem., 30, 880 (1987), Shank, R., et al.: Epilepsia, 35, 450 (1994), Streeter, A., et al.: Drug Metab. Disp., 23, 90 (1995),<br></p>Formula:C9H17NO8SColor and Shape:WhiteMolecular weight:299.306-Fluoro-3-[1-bis-[2-(methyl-6,7,8,9-tetrahydropyridol[1,2,a]pyrimidin-4-one-3-yl)ethyl]piperidinium]benzisoxazole Iodide
Controlled ProductFormula:C34H42FIN6O3Color and Shape:NeatMolecular weight:728.641-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine
CAS:Controlled ProductFormula:C19H29NO2Color and Shape:WhiteMolecular weight:303.44Tianeptine-d12
CAS:Controlled Product<p>Applications Labelled tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.<br>References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991),<br></p>Formula:C21H13D12ClN2O4SColor and Shape:NeatMolecular weight:449.03Pitofenone Hydrochloride
CAS:Controlled Product<p>Applications Diclofenac and its combination with Pitofenone and Fenpiverinium shows antispasmodic activity.<br>References Lundstam, S., et al.: Lancet, 1, 1096 (1982), Thompson, J., et al.: Br. Med. J., 299, 1140 (1989), Marthak, K., et al.: Curr. Med. Res. Opi.,12, 366 (1991),<br></p>Formula:C22H25NO4·ClHColor and Shape:NeatMolecular weight:403.90Methyl 4-((6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)oxy)benzoate
CAS:Purity:97.0%Molecular weight:324.33999633789062-[1-Methyl-5-(trifluoromethyl)pyrazol-3-yl]-thiophene-5-carboxaldehyde
CAS:Formula:C10H7F3N2OSColor and Shape:SolidMolecular weight:260.236-ethyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.36999511718751,2,3,9-Tetrahydro-9-methyl-4H-carbazol-4-one
CAS:<p>Impurity Ondansetron EP Impurity C<br>Applications 1,2,3,9-Tetrahydro-9-(methyl-d3)-4H-carbazol-4-one (Ondansetron EP Impurity C) is used in the preparation of 5-HT3 modulators useful in the treatment and prevention of 5-HT3 receptor-mediated diseases. 1,2,3,9-Tetrahydro-9-methyl-4H-carbazol-4-one is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Huang, W. et al.: Zhong. Yao. Dax. Xueb., 30, 1 (1999); Kim, M. et al.: Heterocycles, 45, 2041 (1997); Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011);<br></p>Formula:C13H13NOColor and Shape:Off-WhiteMolecular weight:199.255,6,7,8-Tetradehydro Risperidone
CAS:Controlled Product<p>Applications 5,6,7,8-Tetradehydro Risperidone is an impurity of risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Formula:C23H23FN4O2Color and Shape:NeatMolecular weight:406.45rac 8,14-Dihydroxy Efavirenz
CAS:Controlled ProductFormula:C14H9ClF3NO4Color and Shape:NeatMolecular weight:347.67Altretamine
CAS:Controlled Product<p>Applications An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic.<br>References Chang, S.C., et al.: Science, 144, 57 (1964), Ames, M.M., et al.: Cancer Res., 39, 5016 (1979), D’Incalci, M., et al.: Br. J. Cancer, 41, 630 (1980),<br></p>Formula:C9H18N6Color and Shape:White Crystalline PowderMolecular weight:210.282-(5-Amino-3-phenylpyrazol-1-yl)ethanol
CAS:Purity:95.0%Color and Shape:Solid, Off-white solidMolecular weight:203.24499511718754-(Methylsulfonyl)phenylacetic Acid
CAS:Controlled Product<p>Applications 4-(Methylsulfonyl)phenylacetic Acid is an intermediate used to prepare heterocyclic diaryl compounds as selective COX-2 inhibitors. It is also used to synthesize hydroxyfuranones as antioxidants and antiinflammatory agents.<br>References Eren, G., et al.: Bioorg. Med. Chem., 18, 6467 (2010); Weber, V., et al.: Bioorg. Med. Chem., 13, 4552 (2005)<br></p>Formula:C9H10O4SColor and Shape:NeatMolecular weight:214.247-Hydroxy Granisetron-d3 Hydrochloride
CAS:Controlled Product<p>Applications 7-Hydroxy Granisetron-d3 Hydrochloride is a labelled Granisetron (G780000) metabolite.<br>References Bloomer, J., et al.: Brit. J. Clin. Pharmacol., 38, 557 (1994), Vernekar, S.,e t al.: J. Med. Chem., 53, 2324 (2010),<br></p>Formula:C182H3H21N4O2·ClHColor and Shape:NeatMolecular weight:367.891-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,6-diol
CAS:Controlled Product<p>Applications 1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine.<br>References Dousa, M. et al.: J. Pharm. Biomed. Anal., 55, 949 (2011);<br></p>Formula:C15H17NO4Color and Shape:NeatMolecular weight:275.301-Amino-3-adamantanol
CAS:Controlled Product<p>Applications Reagent used in the preparation of Vildagliptin.<br>References Fukushima, H., et al.: Bioorg. Med. Chem., 16, 4093 (2008), Anand, R., et al.: J. Med. Chem., 52, 1602 (2009),<br></p>Formula:C10H17NOColor and Shape:NeatMolecular weight:167.25Iloperidone-d3
CAS:Controlled Product<p>Applications Labelled Iloperidone. Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995), Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995), Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996)<br></p>Formula:C24H24D3FN2O4Color and Shape:Light YellowMolecular weight:429.52-Chloro-2',4'-difluoroacetophenone
CAS:Controlled Product<p>Applications A α-haloacetophenone derivatives tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B.<br>References Taylor, S., et al.: Bioorg. Med. Chem., 6, 1457 (1998), Taing, M., et al.: Biochemistry, 38, 3793 (1999), Shen, K., et al.: J. Biol. Chem., 276, 47311 (2001),<br></p>Formula:C8H5ClF2OColor and Shape:NeatMolecular weight:190.57(2E)-1-(1H-1,2,3-Benzotriazol-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one
CAS:Molecular weight:255.3000030517578Carisoprodol-d3
CAS:Controlled Product<p>Applications Muscle relaxant (skeletal).<br>References Musso, D., et al.: J. Med. Chem. 46, 399 (2003), Newman, P., et al.: Eur. J. Clin. Pharm., 23, 31 (1982).<br></p>Formula:C122H3H21N2O4Color and Shape:White PowderMolecular weight:263.351-des(piperidin-3R-amino)-1-chloro-Alogliptin
CAS:Controlled Product<p>Impurity Alogliptin 6-Chloro Impurity<br>Applications Alogliptin (A575425) intermediate.<br></p>Formula:C13H10ClN3O2Color and Shape:NeatMolecular weight:275.69(Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)acetic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:356.41000366210945-Amino-1-cyclopropyl-6,7-difluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Purity:95+%Molecular weight:294.257995605468752,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Controlled Product<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Formula:C13H14F3N3OColor and Shape:NeatMolecular weight:285.26Methyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:253.61000061035156Tryptophol
CAS:Controlled Product<p>Applications Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.<br>References Cornford, E.M., et al.: J Clin Invest, 63, 1241-1248 (1979)<br></p>Formula:C10H11NOColor and Shape:NeatMolecular weight:161.2N-2 Trityl Olmesartan Medoxomil
CAS:<p>Impurity Olmesartan Medoxomil EP Impurity D<br>Applications Olmesartan medoxomil intermediate.<br>References Birkenhager, W., et al.: J. Hypertens, 17, 873 (1999), Whittaker, A., et al.: Br. J. Cardiol., 12, 125 (2005),<br></p>Formula:C48H44N6O6Color and Shape:White To Light YellowMolecular weight:800.906-ethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.3699951171875N-Formyl Oxcarbazepine
CAS:Controlled Product<p>Applications N-Formyl Oxcarbazepine is an impurity of the anticonvulsant Oxcarbazepine (O869250).<br></p>Formula:C16H12N2O3Color and Shape:NeatMolecular weight:280.28N-Methyl-O-(10H-phenothiazine-10-carbonyl)hydroxylamine hydrochloride
CAS:Purity:95%Molecular weight:308.7799987792969Tenoxicam-d4
CAS:Controlled Product<p>Applications Labelled Tenoxicam (T019500). Nonsteroidal anti-inflamatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bird, H.A., et al.: Curr. Med. Res. Opin., 8, 9 (1982), Gonzalez, J.P., et al.: Drugs, 34, 289 (1987), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs. Excip., 22, 431 (1993),<br></p>Formula:C13D4H7N3O4S2Color and Shape:Light YellowMolecular weight:341.399(R)-1-(2-Bromopyridin-4-yl)ethanamine dihydrochloride
CAS:Purity:97.0%Molecular weight:273.98001098632818-tert-butyl-4-(thiophene-2-carbonyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:351.4599914550781O-Methyl Meloxicam
CAS:<p>Applications O-Methyl Meloxicam is an impurity of Meloxicam (M216100).<br></p>Formula:C15H15N3O4S2Color and Shape:NeatMolecular weight:365.43(S)-Ketamine Hydrochloride
CAS:Controlled Product<p>Applications (S)-Ketamine is the more active enantiomer of the NMDA receptor antagonist and anesthetic agent Ketamine (K165300). Controlled Substance.<br>References Meliska, C.J. et al.: J. Pharmacol Exp. Therap., 212, 206 (1980); Smith, D.J. et al.: Neuropharmacology, 20, 391 (1981); Klockgether-Radke, A.P. et al.: Eur. J. Anaesthesiol., 22, 215 (2005);<br></p>Formula:C13H16ClNO·ClHColor and Shape:Off-WhiteMolecular weight:274.1862Felodipine-13C4, d3
CAS:Controlled Product<p>Applications Felodipine-13C4, d3 is the labeled analogue of Felodipine (F232375), a dihydropyridine calcium channel blocker.<br>References Berntsson, P.B., et al.: Acta Pharm. Suec., 18, 221 (1981); Kratochwil, N., et al.: Biochem. Pharmacol., 64, 1355 (2002); O'Brien, S., et al.: J. Med. Chem., 48, 1287 (2005); Castilho, M., et al.: Bioorg. Med. Chem., 14, 516 (2006)<br></p>Formula:C1413C4H16D3Cl2NO4Color and Shape:NeatMolecular weight:391.24Imazamox
CAS:Controlled Product<p>Applications Imazamox is an imidazolinone based acetolactate synthase inhibitor that is utilized as a herbicide for weed control.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Riar, D.S., et al.: Int. J. Agron., 8 (2012); Grey, T.L., et al.: Weed. Technol., 26, 405 (2012); Rousonelos, S.L., et al.: Weed. Sci., 60, 335 (2012);<br></p>Formula:C15H19N3O4Color and Shape:WhiteMolecular weight:305.337-chloro-4-methoxy-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:305.7799987792969Pentoxifylline
CAS:Controlled ProductFormula:C13H18N4O3Color and Shape:White To Off-WhiteMolecular weight:278.313',4'-Dihydroxyacetophenone
CAS:Controlled Product<p>Applications 3',4'-Dihydroxyacetophenone is an active constituent of Chinese medicine and also has antimelanogenic actiivity.<br>References Kim. Y., et al.: Biosci., Biotech., Biochem., 70, 532 (2006); Yang, D., et al.: Prostaglandins, 38, 497 (1989)<br></p>Formula:C8H8O3Color and Shape:NeatMolecular weight:152.15Lansoprazole Sulfone
CAS:<p>Impurity Lansoprazole USP Related Compound A<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor. Lansoprazole USP Related Compound A.<br>References De Morais, S., et al.: Mol. Pharmacol., 46, 594 (1994), Spencer, C., et al.: Drugs, 48, 404 (1994), Pearce, R., et al.: J. Pharmacol. Exp. Ther., 277, 805 (1996), Tassaneeyakul, W., et al.: Br. J. Clin. Pharmacol., 49, 139 (2000),<br></p>Formula:C16H14F3N3O3SColor and Shape:NeatMolecular weight:385.36(2-methoxyethyl)(2-thienylmethyl)amine hydrochloride
CAS:Formula:C8H14ClNOSColor and Shape:SolidMolecular weight:207.72Dipyridamole
CAS:Controlled Product<p>Applications Selective inhibitor of phosphodiesterase V (PDE 5); potent coronary vasodilator drug; adenosine transport inhibitor; inhibitor of platelet aggregation.<br>References Buchalter, M.B., et al.: Postgrad. Med. J., 66, 531 (1990), Sundaram, M., et al.: J. Biol. Chem., 273, 21519 (1998), Denis, D., et al.: Eur. J. Pharmacol., 367, 343 (1999),<br></p>Formula:C24H40N8O4Color and Shape:YellowMolecular weight:504.632-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine Dihydrochloride
CAS:Controlled Product<p>Applications 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine Dihydrochloride is an impurity of Chlorpromazine (C424750), which is used as an antiemetic; antipsychotic. 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine is also used in the synthesis of novel phenothiazine compounds with antimalarial activity.<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970); Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990); Kalkanidis, M., et. al.: Biochem. Pharmacol., 63, 833 (2002)<br></p>Formula:C21H28ClN3S•2HClColor and Shape:NeatMolecular weight:462.91Levetiracetam Carboxylic Acid
CAS:Controlled ProductFormula:C8H13NO3Color and Shape:White To Off-WhiteMolecular weight:171.192-Mercapto-N-methyl-benzamide
CAS:Controlled Product<p>Stability Air Sensitive<br>Applications 2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),<br></p>Formula:C8H9NOSColor and Shape:BeigeMolecular weight:167.228Zomepirac Acyl-O-β-D-glucuronide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An unstable metabolite of the nonsteroidal anti-inflammatory drug (NSAID) Zomepirac (Z675000) that is capable of reacting with endogenous proteins to form potentially toxic covalent ZP-protein adducts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References King, A.R. et al.: J. Phamacol. Toxicol. Meth., 36, 131 (1996); Olsen, J. et al.: Chem. Res. Toxicol., 18, 1729 (2005); O’Neill, P.J. et al.: J. Clin. Pharmacol., 22, 470 (1982);<br></p>Formula:C21H22ClNO9Color and Shape:BeigeMolecular weight:467.852-Chloro-10,11-dihydro-11-oxo-dibenzo[b,f][1,4]oxazepine
CAS:Controlled ProductFormula:C13H8ClNO2Color and Shape:NeatMolecular weight:245.66Vildagliptin Cyclo Imidamide
CAS:<p>Applications Vildagliptin Cyclo Imidamide Hydrochloride is an impurity of vildagliptin (V305000). Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. ASide from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C17H25N3O2Color and Shape:NeatMolecular weight:303.409,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid(RS-Ofloxacin Carboxylic Acid)
CAS:Formula:C13H9F2NO4Color and Shape:Off-WhiteMolecular weight:281.21Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (85%) (Famotidine Impurity)
CAS:Controlled ProductFormula:C10H14N8S4Color and Shape:Off-WhiteMolecular weight:374.53
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