Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Found 79382 products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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Amlodipine EP Impurity D (Fumarate salt)
CAS:Formula:C20H23ClN2O5C4H4O4Molecular weight:406.9 : 116.14-(2-Aminophenyl)-3-morpholinone
CAS:<p>Applications 4-(2-Aminophenyl)-3-morpholinone is a reagent used in the preparation of various Morpholine based pharmaceuticals.<br>References Mederski, W., et al.: Bioorg. Med. Chem. Lett., 14, 3763 (2004), Roehrig, S., et al.: J. Med. Chem., 48, 5900 (2005),<br></p>Formula:C10H12N2O2Color and Shape:Off White SolidMolecular weight:192.214Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Formula:C31H38ClN7O7S2•xH2OColor and Shape:White To Off-WhiteMolecular weight:720.26Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate
CAS:<p>Applications Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is used in the synthesis of the major metabolites of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Li, X., et. al.: Lett. Org. Chem., 12, 217 (2015); Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C13H13NO3SColor and Shape:NeatMolecular weight:263.312-(2-Aminoethylamino)ethanol
CAS:Controlled Product<p>Applications 2-(2-Aminoethylamino)ethanol is a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Its used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013);<br></p>Formula:C4H12N2OColor and Shape:NeatMolecular weight:104.1509Methylamine Hydrochloride
CAS:Controlled Product<p>Applications Methanamine Hydrochloride is used in the synthesis of betaine-homocysteine S-methyltransferase. Also used in the synthesis of novel oxazinones as polymerase inhibitors.<br>References Picha, J. et al.: Eur. J. Med. Chem., 65, 256 (2013); Gangloff, A. et al.: Bioorg. Med. Chem. Lett., 23, 4501 (2013);<br></p>Formula:CH5N·HClColor and Shape:White To Off-WhiteMolecular weight:67.518Riluzole Dimer Impurity
Controlled Product<p>Applications Riluzole Dimer Impurity is an impurity of Rifuzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Formula:C17H10F6N4O2S2Color and Shape:NeatMolecular weight:480.415-Chloro-2-Thiophenecarboxylic Acid 4-Nitrophenyl Ester
CAS:Controlled ProductFormula:C11H6ClNO4SColor and Shape:NeatMolecular weight:283.69Tacrolimus (FK506)
CAS:<p>Applications An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Asano, K., et al.: In Vivo, 10, 537 (1996), McCall, E., et al.: Circ. Res., 79, 1110 (1996), Raufman, J.P., et al.: J. Biol. Chem., 271, 19877 (1996), Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318, 1104 (1999)<br></p>Formula:C44H69NO12Color and Shape:NeatMolecular weight:804.02Diclofenac-13C6
CAS:<p>Applications Diclofenac-13C6 is a labelled analogue of Diclofenac Acid (D436465), which is a nonsteroidal anti-inflammatory compound and decycloxygenase (COX) inhibitor. Diclofenac-13C6 is also an intermediate in synthesizing Diclofenac-13C6 Sodium Salt (D436453), which is a labelled analogue of Diclofenac Sodium Salt (D436450).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yagi, K., et. al.: Biol. Pharm. Bull., 37, 1234 (2014); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004); Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004), Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009)<br></p>Formula:C813C6H11Cl2NO2Color and Shape:NeatMolecular weight:302.1
