Sulfonamides and Derivatives
Sulphonamides are compounds that contain a sulphonamide functional group (-SO₂NH₂), where a sulphur atom is bonded to an amino group. They were among the first synthetic antibiotics used in medicine, inhibiting folic acid synthesis in bacteria, which gives them antimicrobial properties. They are mainly used to treat bacterial infections, although their use has declined due to antimicrobial resistance. In addition to their use as antibiotics, sulphonamides also have applications in the treatment of diseases such as malaria and inflammatory bowel diseases.
At CymitQuimica, we offer high-purity sulphonamides and their derivatives for research in microbiology and pharmaceutical development.
Found 2587 products of "Sulfonamides and Derivatives"
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rac 2-Hydroxy Ibuprofen
CAS:Controlled Product<p>Applications A human metabolite of Ibuprofen.<br>References Bales, J., et al.: Clin. Chem., 31, 757 (1985), Maurer, H., et al.: J. Anal. Toxicol., 25, 237 (2001), Zwiener, C., et al.: Anal. Bioanal. Chem., 372, 569 ( 2002), de Bernardi, B., et al.: J. Clin. Oncol., 21, 1592 (2003),<br></p>Formula:C13H18O3Color and Shape:Off-WhiteMolecular weight:222.284,4'-Bis(4-aminobenzenesulfonyl)hydrazobenzene
<p>Stability Light Sensitive<br>Applications 4,4'-Bis(4-aminobenzenesulfonyl)hydrazobenzene is a dimer impurity of Dapsone (D193250); an antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950); Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009); Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009); Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)<br></p>Formula:C24H22N4O4S2Color and Shape:Off WhiteMolecular weight:494.59Brinzolamide Hydrochloride
CAS:Controlled Product<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Formula:C12H21N3O5S3·ClHColor and Shape:NeatMolecular weight:419.97Hydrochlorothiazide
CAS:Formula:C7H8ClN3O4S2Color and Shape:White Crystalline PowderMolecular weight:297.74Methazolamide
CAS:Controlled Product<p>Applications Methazolamide is a carbonic anhydrase inhibitor. Methazolamide is used in the treatment of glaucoma.<br>References Iyer, G.R. et al.: J. Pharmac. Biomed. Anal., 16, 1021 (1998); Maren, T. H. et al.: Invest. Ophthamol. Vis. Sci., 16, 730 (1977);<br></p>Formula:C5H8N4O3S2Color and Shape:NeatMolecular weight:236.277-Ethyltryptophol
CAS:<p>Impurity Etodolac EP Impurity H<br>Applications 7-Ethyltryptophol (Etodolac EP Impurity H) is a key intermediate in the preparation of the non-steroidal anti-inflammatory drug Etodolac.<br>References El Kousy, N., et al.: J. Pharm. Biomed. Anal., 20, 185 (1999),<br></p>Formula:C12H15NOColor and Shape:WhiteMolecular weight:189.25Tolnaftate
CAS:Controlled Product<p>Applications Antifungal.<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Formula:C19H17NOSColor and Shape:NeatMolecular weight:307.41Sulfachloropyridazine
CAS:<p>Applications Sulfachloropyridazine is an antibacterial compound.This compound is a contaminant of emerging concern (CECs).<br>References Wammer, K.: Environ. Toxicol. Chem. 25, 1480 (2006);<br></p>Formula:C10H9ClN4O2SColor and Shape:WhiteMolecular weight:284.72N-Acetyl Sulfadiazine-d4 (Major)
CAS:Controlled Product<p>Applications A major labelled metabolite of Sulfadiazine.<br>References Woolley, J., et al.: Drug Metab. Dispos., 7, 94 (1979), Nielsen, P., et al.: Biochem. Pharmacol., 35, 2509 (1986), Anari, M., et al.: Anal. Chem., 76, 823 (2004), Edlund, P., et al.: J. Pharm. Biomed. Anal., 34, 1079 (2004),<br></p>Formula:C12H8D4N4O3SColor and Shape:NeatMolecular weight:296.345-(Acetylamino)-1,3,4-thiadiazole-2-sulfonic Acid Potassium Salt
CAS:Controlled Product<p>Impurity Acetazolamide EP Impurity E<br>Applications 5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonic Acid is an impurity of Acetazolamide (A161500). (Acetazolamide EP impurity E)<br>References Zarghi, A., et al.: J. Pharm. Biomed. Anal., 28, 169 (2002), Subbarao, D., et al.: J. Chromatogr., 67, 841 (2008),<br></p>Formula:C4H4KN3O4S2Color and Shape:NeatMolecular weight:261.32p-Ethylhydratropic Acid
CAS:<p>Impurity Ibuprofen EP Impurity N<br>Applications p-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).<br></p>Formula:C11H14O2Color and Shape:WhiteMolecular weight:178.233-(4-Isobutylphenyl)propanoic Acid
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity F<br>Applications 3-(4-Isobutylphenyl)propanoic acid (Ibuprofen EP Impurity F) is an impurity of Ibuprofen (I140000). Ibuprofen impurity F as per EP.<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),<br></p>Formula:C13H18O2Color and Shape:NeatMolecular weight:206.285-Oxomefruside
CAS:<p>Applications 5-Oxomefruside is a lactone metabolite and impurity of the drug Mefruside (M205150).<br>References Puetter, J., et al.: Biochimica et Biophysica Acta, General Subjects, 286, 186 (1972).<br></p>Formula:C13H17ClN2O6S2Color and Shape:NeatMolecular weight:396.87Bumetanide 3-(Butyl(nitroso)amino)
CAS:Controlled Product<p>Impurity Bumetanide Impurity<br>Applications Bumetanide 3-(Butyl(nitroso)amino) is an impurity of Bumetanide(B689550). Bumetanide is a diuretic.<br>References Ward, A., et al.: Drugs, 28, 426 (1984), Gradeen, C.Y, et al.: J. Anal. Toxicol., 14, 123 (1990), Tata, P.N.V., et al.: Anal. Profiles Drug Subs. Excip., 22, 107 (1993),<br></p>Formula:C17H19N3O6SColor and Shape:NeatMolecular weight:393.41(±)-Ibuprofen Methyl Ester
CAS:Controlled Product<p>Applications (±)-Ibuprofen Methyl Ester is a phototoxic, photoproduct of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen is also used as an anti-inflammatory drug.<br>References Miranda, M.A., et. al.: Toxicol. In Vitro, 5, 451 (1991); Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Formula:C14H20O2Color and Shape:ColourlessMolecular weight:220.315-Aminosalicylic Acid-13C6 Hydrochloride (Mesalazine-13C6 Hydrochloride)
CAS:Controlled ProductFormula:C13C6H7NO3·HClColor and Shape:NeatMolecular weight:195.55Quininone
CAS:<p>Applications Quininone has been shown to have antimalarial activity in mice. Quininone has been shown to aid the binding of drug-induced antibodies to human platelets.<br>References Klayman, D.L., et. al.: J. Med. Chem., 16, 1042 (1973); Christie, D.J., et. al.: J. Lab. Clin. Med., 104, 730 (1984)<br></p>Formula:C20H22N2O2Color and Shape:White To Light BeigeMolecular weight:322.40Acetaminophen (1 mg/mL in Methanol)
CAS:Controlled ProductFormula:C8H9NO2Color and Shape:Single SolutionMolecular weight:151.16Aceclofenac Ethyl Ester
CAS:Controlled Product<p>Impurity Aceclofenac EP Impurity E<br>Applications Aceclofenac Ethyl Ester is a 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative used as an anti-inflammmatory and analgesic agent. Aceclofenac EP Impurity E.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yscla, A., et al.: Drugs Exp. Clin. Res., 14, 491 (1988), Ballesteros, R., et al.: Clin. Trials J., 27, 12 (1990)<br></p>Formula:C18H17Cl2NO4Color and Shape:White To Light YellowMolecular weight:382.24Isosulfamethoxazole
CAS:<p>Applications Isosulfamethoxazole is an impurity of the antibacterial drug Sulfamethoxazole (S699086). It is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 467 (1973), Wormser, G.P., et al.: Drugs, 24, 459 (1982), Wharton, M., et al.: Ann. Intern. Med., 105, 37 (1986),<br></p>Formula:C10H11N3O3SColor and Shape:NeatMolecular weight:253.283-(N-Acetyl-L-cystein-S-yl) Acetaminophen
CAS:Controlled Product<p>Stability Very Hygroscopic<br>Applications Paracetamol Mercapturate is a metabolite of Acetaminophen (A161220) (1,2). Acetaminophen is a widely used analgesic and antipyretic drug. It can also be used in biological study of urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation.<br>References (1) Trettin, A., et al.: J. Chromatogr. B., 963, 105 (2014) (2) Pickering, G., et al.: Clin. Pharmacol. Ther., 90, 707 (2011)<br></p>Formula:C13H16N2O5SColor and Shape:NeatMolecular weight:312.342,4-Disulfamyl-5-trifluoromethylaniline
CAS:Formula:C7H8F3N3O4S2Color and Shape:White To Off-WhiteMolecular weight:319.28Oxyclozanide
CAS:<p>Applications Oxyclozanide, an anthelmintic drug displays strong in vivo and vitro activity against methicillin resistant S. aureus and Gram-positive bacteria Enterococcus faecium.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rajamuthiah, R., et al.: PLOS ONE, 10, 1-19 (2015)<br></p>Formula:C13H6Cl5NO3Color and Shape:NeatMolecular weight:401.466-Hydroxy Etodolac
CAS:Controlled Product<p>Applications 6-Hydroxy Etodolac is an Etodolac (E933100) metabolite.<br>References Humber, L., et al.: J. Med. Chem., 32, 2582 (1989), Koupai-Abyazani, M., et al.: J. Anal. Toxicol., 23, 200 (1999),<br></p>Formula:C17H21NO4Color and Shape:NeatMolecular weight:303.35(-)-(3S)-3-Hydroxy Quinine
CAS:Controlled ProductFormula:C20H24N2O3Color and Shape:NeatMolecular weight:340.42Triflusulfuron-methyl
CAS:Controlled Product<p>Applications Triflusulfuron-methyl, is a widely used sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, N., et al.: Huanjing Kexue, 33, 4400 (2012);<br></p>Formula:C17H19F3N6O6SColor and Shape:WhiteMolecular weight:492.43Acetaminophen Dimer-d6
CAS:Controlled Product<p>Applications Acetaminophen Dimer-d6 is deuterium labeled Acetaminophen Dimer (A161235). Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)(3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Formula:C16H10D6N2O4Color and Shape:NeatMolecular weight:306.35O,O-Di-2-Naphthalenyl Ester Carbonothioic Acid
CAS:Formula:C21H14O2SColor and Shape:NeatMolecular weight:330.4rac-Ibuprofen Amide
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity C<br>Applications An impurity of Ibuprofen (I140000).<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Sochor, J., et al.: J. Pharm. Biomed. Anal., 13, 899 (1995),<br></p>Formula:C13H19NOColor and Shape:WhiteMolecular weight:205.30ortho Gliclazide
CAS:<p>Applications Impurity of Gliclazide (G409875).<br>References Hisashi, M., et al.: Eur. J. Drug Metab. Pharmacokinet., 8, 117 (1983),<br></p>Formula:C15H21N3O3SColor and Shape:WhiteMolecular weight:323.41Sulfadoxine-d4
CAS:Controlled Product<p>Applications Labelled Sulfadoxine (S699070). Used as an antibacterial.<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs., 17, 571 (1988)<br></p>Formula:C12D4H10N4O4SColor and Shape:NeatMolecular weight:314.35Ibuprofen-13C,d3
CAS:Controlled ProductFormula:C1213CH15D3O2Color and Shape:NeatMolecular weight:210.294',6'-Dinitro-2'-phenoxymethanesulfonanilide
CAS:<p>Impurity Nimesulide EP Impurity A<br>Applications 4',6'-Dinitro-2'-phenoxymethanesulfonanilide, is an impurity of the drug Nimesulide (N477500), which is an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)<br></p>Formula:C13H11N3O7SColor and Shape:NeatMolecular weight:353.31rac α-Hydroxy Ibuprofen
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity M<br>Applications A potential precursor of Ibuprofen and Naproxen. Antiinflammatory agent.<br>References Williams, K., et al.: Pharm. Ther., 46, 273 (1990), Evans, A., et al.: Eur. J. Clin. Pharmacol., 42, 237 (1992), Tucker, G., et al.: Lancet, 355, 1085 (2000), Tan, S., et al.: Xenobiotica, 32, 683 (2002), Fura, A., et al.: J. Pharm. Biomed. Anal., 32, 513 (2003),<br></p>Formula:C13H18O3Color and Shape:White To Off-WhiteMolecular weight:222.283-Desmethoxy-3-bromo Trimethoprim
CAS:Controlled Product<p>Applications An impurity of Trimethoprim (T795615) with inhibitory effects on the enzyme dihydrofolate reductase.<br>References Kompis, I. et al.: Enzyme Inhib. Proc. Meet., 177 (1980); Hess, S. et al.: J. Pharmac. Biomed. Anal., 25, 531 (2001);<br></p>Formula:C13H15BrN4O2Color and Shape:NeatMolecular weight:339.19N-Desbutyl-N-(2-ethylhexyl) Bumetanide (~90% Purity)
CAS:<p>Applications N-Desbutyl-N-(2-ethylhexyl) Bumetanide is an analogue of the diuretic, Bumetanide (B689550).<br>References Petzinger, E. et al.: Am. J. Physiol., 265, G942 (1993);<br></p>Formula:C21H28N2O5SPurity:~90%Color and Shape:NeatMolecular weight:420.5224Ibuprofen Isopropyl Ester
CAS:Controlled Product<p>Applications Ibuprofen Isopropyl Ester is a prodrug of Ibuprofen (I140000). It might improve topical delivery of ibuprofen.<br>References Bansal, A., et al.: Drug Dev. Ind. Pharm., 20, 2025 (1994); Bansal, A., et al.: Indian J. Exp. Bio., 39, 280 (2001)<br></p>Formula:C16H24O2Color and Shape:NeatMolecular weight:248.36Piroxicam-d3
CAS:Controlled Product<p>Applications Non-steroidal anti-inflammatory with long half-life. Cyclooxygenase inhibitor. Clinically useful NSAID.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carty, T.J., et al.: Prostaglandins, 47, 55 (1980), Brogden, R.N., et al.: Drugs, 22, 165 (1981), Mihalic, M., et al.: Anal. Profiles Drug Subs., 15, 509 (1986), Laneauville., O., et al.: J. Pharmacol. Exp. Ther., 271, 927 (1994),<br></p>Formula:C152H3H10N3O4SColor and Shape:NeatMolecular weight:334.36Gliquidone
CAS:Controlled Product<p>Applications Gliquidone is an anti diabetic agent used in the treatment of hypoglycemia which leads to an increased risk in diabetic cardiovascular disease. Also used in the treatment diabetic nephropathy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tan, Z. et al.: Chinese Med. J., 127, 1298 (2014); Ke, J, et al.: J. Endocrinol., 220, 129 (2014);<br></p>Formula:C27H33N3O6SColor and Shape:NeatMolecular weight:527.632,4-Dichlorobenzoic Acid
CAS:Controlled Product<p>Impurity Furosemide EP Impurity E<br>Applications 2,4-Dichlorobenzoic Acid (Furosemide EP Impurity E) is a di-halogenated benzoic acid derivative and an intermediate in the synthesis of spirodiclofen (S682990), a tetronic acid acaricide fungicide used in controlling red mites.<br>References Cho, Y.C., et al.: FEMS. MIcrobiol. Ecol., 42, 51 (2002); Corbella, M.E., et al.: Biodegradation., 12, 149 (2001);<br></p>Formula:C7H4Cl2O2Color and Shape:White To Off-WhiteMolecular weight:191.013-Methoxy Acetaminophen
CAS:<p>Applications 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C9H11NO3Color and Shape:NeatMolecular weight:181.192-[4-(2-Methylpropenyl)phenyl]propionic Acid
CAS:<p>Applications 2-[4-(2-Methylpropenyl)phenyl]propionic Acid is a byproduct of Ibuprofen (I140000(P)), which is an anti-inflammatory drug.<br>References Sharma, K., et al.: Int. J. Environ. Sci. Tech., 16, 8315 (2019)<br></p>Formula:C13H16O2Color and Shape:Light YellowMolecular weight:204.262-Amino-4-methylamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
CAS:Controlled ProductFormula:C15H20N4O3Color and Shape:NeatMolecular weight:304.34Nicosulfuron-d6
CAS:Controlled Product<p>Applications Post-emergence sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gubbiga, N.G., et al.: Weed Technol., 9, 574 (1995), Ukrainczyk, L., et al.: J. Agric. Food Chem., 43, 855 (1995)<br></p>Formula:C152H6H12N6O6SColor and Shape:NeatMolecular weight:416.44cis-Glimepiride
CAS:Controlled Product<p>Impurity Glimepiride EP Impurity A<br>Applications cis-Glimepiride (Glimepiride EP Impurity A) is the cis-isomer of Glimepiride found in a bulk drug substance.<br>References Drummer, O., et al.: Anal. Toxicol., 17, 225 (1993), Magni, F., et al.: Anal. Biochem., 282, 136 (2000), Khan, M., et al.: J. Pharma. Biomed. Anal., 39, 928 (2005),<br></p>Formula:C24H34N4O5SColor and Shape:NeatMolecular weight:490.624-Hydroxy Triamterene
CAS:Controlled Product<p>Applications A metabolite of Triamterne, a diuretic agent.<br>References Vollmer, G., et al.: Arzneim.-Forsch., 31, 529 (1981), Gilfrich, H.J., et al.: Eur. J. Clin. Pharmacol., 25, 237 (1983),<br></p>Formula:C12H11N7OColor and Shape:NeatMolecular weight:269.26trans-Hydroxy Glimepiride
CAS:Controlled Product<p>Applications An active metabolite of Glimepiride.<br>References Muller, G., et al.: Diabetes, 42, 1852 (1993), Kramer, W., et al.: Biochem. Biophys. Acta, 119, 278 (1994),<br></p>Formula:C24H34N4O6SColor and Shape:NeatMolecular weight:506.62Tolbutamide
CAS:Controlled ProductFormula:C12H18N2O3SColor and Shape:Off-WhiteMolecular weight:270.352-(4-Isobutylphenyl)propanal
CAS:<p>Stability Hygroscopic<br>Applications 2-(4-Isobutylphenyl)propanal is an impurity of the drug Ibuprofen (I140000), a selective cyclooxygenase inhibitor that also inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016)<br></p>Formula:C13H18OColor and Shape:NeatMolecular weight:190.28Gliclazide
CAS:<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972), Holmes, B., et al.: Drugs, 27, 301 (1984),<br></p>Formula:C15H21N3O3SColor and Shape:NeatMolecular weight:323.415-Hydroxy Indapamide
CAS:Controlled Product<p>Applications 5-Hydroxy Indapamide is a major metabolite of Indapamide (I500100), and possesses similar antihypertensive and diuretic properties.<br>References Slater, T., et al.: Biochem. J., 222, 1 (1984), Josephson, R., et al.: J. Biol. Chem., 266, 2354 (1991), Del Rio, M., et al.: Eur. J. Pharm., 250, 133 (1993), Calder, J., et al.: Eur. J. Pharma., 256, 185 (1994),<br></p>Formula:C16H16ClN3O4SColor and Shape:NeatMolecular weight:381.83Sulfadimethoxine
CAS:Controlled Product<p>Applications Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Seki, et al.: Arzneim.-Forsch., 15, 1441 (1965), Bohni, et al.: Chemotherapy, 14, 195 (1969),<br></p>Formula:C12H14N4O4SColor and Shape:Off-WhiteMolecular weight:310.33Saccharin-d4
CAS:Controlled Product<p>Applications Labelled Saccharin (S080800). It is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing.<br>References Taylor, J.D., et al.: Food Cosmet. Toxicol., 6, 313 (1968), Arnold, D.L., et al.: Fundam. Appl. Toxicol., 4, 674 (1984), Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds<br></p>Formula:C72H4HNO3SColor and Shape:White To Off-WhiteMolecular weight:187.21Metribuzin DK
CAS:Controlled Product<p>Applications Metribuzin DK is a selective triazine herbicide used in the control of broadleaf weeds. Used in the protection of vegetable and fruit crops. Pesticide.<br>References Xie, Y. et al.: Microchem. J., 133, 468 (2017);<br></p>Formula:C7H12N4O2Color and Shape:NeatMolecular weight:184.201-[4-(1-Hydroxy-2-methylpropyl)phenyl]ethanone
CAS:Formula:C12H16O2Color and Shape:Light BrownMolecular weight:192.254Xipamide
CAS:Controlled Product<p>Applications Xipamide is a diuretic and antihypertensive agent.<br>References Wagieh, N., et al.: Drug Test. Anal., 2, 113 (2010), Prado-Prado, F., et al.: Bioorg. Med. Chem., 18, 2225 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Formula:C15H15ClN2O4SColor and Shape:NeatMolecular weight:354.81Cantrodifene
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications 4-Isothiocyanato-4'-nitrodiphenyl ether (cas# 19881-18-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C13H8N2O3SColor and Shape:NeatMolecular weight:272.27N-(2-Pyridyl)oxamic Acid
CAS:Controlled Product<p>Applications A metabolite of Tenoxicam (T019500). A degradation product and pathway of Lornoxicam.<br>References Tsuchiya, S., et al.: Cancer Res., 42, 1530 (1982), Talanian, R., et al.: J. Med. Chem., 43, 3351 (2000), Fuentes-Prior, P., et al.: Biochem. J., 384, 201 (2004), Han, Y., et al.: Bioorg. Med. Chem. Lett., 15, 1173 (2005),<br></p>Formula:C7H6N2O3Color and Shape:WhiteMolecular weight:166.13Nimesulide
CAS:<p>Applications Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)<br></p>Formula:C13H12N2O5SColor and Shape:Light YellowMolecular weight:308.31N-Methyl Metribuzin
CAS:Controlled ProductFormula:C9H16N4OSColor and Shape:NeatMolecular weight:228.31Mesosulfuron-methyl
CAS:<p>Stability Unstable in Solution<br>Applications Mesosulfuron-methyl can be used in biological study of targeted screening and safety evaluation of 276 agrochemical residues in raisins using buffered ethyl acetate extraction and liquid chromatography-tandem mass spectrometry analysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shabeer, T. P. A., et al.: Chemosphere, 184, 1036 (2017)<br></p>Formula:C17H21N5O9S2Color and Shape:NeatMolecular weight:503.51Bis(4-hydroxyphenyl) Sulfone
CAS:Controlled Product<p>Applications Bis(4-hydroxyphenyl) Sulfone is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.<br>References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012);<br></p>Formula:C12H10O4SColor and Shape:WhiteMolecular weight:250.27N-Nitroso Furosemide ( >80%)
CAS:Formula:C12H10ClN3O6SPurity:>80%Color and Shape:Light Orange To Dark Orange4-Acetamidobenzenesulfonic Acid
CAS:Controlled Product<p>Impurity Sulfadimethoxine EP Impurity C<br>Stability Hygroscopic<br>Applications 4-Acetamidobenzenesulfonic Acid (Sulfadimethoxine EP Impurity C) is a metabolite of Sulfanilic acid.<br>References Saab, N., et al.: Eur. J. Med. Chem., 34, 745 (1999), Kim, H., et al.: J. Pharm. Biomed. Anal., 27, 51 (2002), Santelli-Rouvier, C., et al.: Eur. J. Med. Chem., 39, 735 (2004),<br></p>Formula:C8H9NO4SColor and Shape:NeatMolecular weight:215.23Acetanilide (Acetylaniline)
CAS:Controlled Product<p>Impurity Paracetamol EP Impurity D<br>Applications Acetanilide (Acetylaniline) the first aniline derivative found to possess analgesic and antipyretic properties (1,2). It is also an impurity of Acetaminophen (A161220).<br>References (1) Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010) (2) Chang, C., et al.: J. Nat. Prod., 73, 229 (2010)<br></p>Formula:C8H9NOColor and Shape:White To Light BrownMolecular weight:135.163-Desmethyl Trimethoprim
CAS:Controlled Product<p>Applications 3-Desmethyl Trimethoprim is a metabolite of Trimethoprim (T795615); an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 3-Desmethyl Trimethoprim gets excreted in the urine of rats, dogs, and man in the form of glucuronides.<br>References Roth, B., et al.: J. Med. Chem., 24, 933 (1981); Liu, Z., et al.: Biomed. Chromatogr., 26, 1101 (2012); Schwartz, D. E., Arzneimittel-Forsch., 20, 1867 (1970)<br></p>Formula:C13H16N4O3Color and Shape:White To Light BrownMolecular weight:276.296,6'-Oxybis-2-naphthalenesulfonic Acid Disodium Salt (>85%)
CAS:Controlled Product<p>Applications An impurity contained in the commercial food Yellow No.5 (Sunset Yellow FCF) which has a potent mutagenicity effect.<br>References Yamada, M., et al.: Chem. Pharm. Bull., 44, 1624 (1996), Yamada, M., et al.: J. Food Chem., 3, 151 (1996),<br></p>Formula:C20H12O7S2·2NaPurity:>90%Color and Shape:White To Light GreyMolecular weight:474.415-Amino-1,3,4-thiadiazole-2-sulfonamide Hydrochloride Salt
CAS:Controlled Product<p>Impurity Acetazolamide EP Impurity D Hydrochloride<br>Applications Acetazolamide intermediate. (Acetazolamide EP Impurity D Hydrochloride)<br>References Carta, F., et al.: Bioorg. Med. Chem. Lett., 19, 6649 (2009), Joseph, P., et al.: J. Med. Chem., 53, 2277 (2010), Srinivasu, P., et al.: J. Pharm. Biomed. Anal., 52, 142 (2010),<br></p>Formula:C2H5ClN4O2S2Color and Shape:NeatMolecular weight:216.673-Hydroxyacetaminophen
CAS:Controlled Product<p>Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Formula:C8H9NO3Color and Shape:NeatMolecular weight:167.16Dimethyl n-methylsulfamide
CAS:Purity:97.0%Color and Shape:Liquid, ClearMolecular weight:138.19000244140625Terizidone-15N2,d6 (Major)
CAS:Controlled Product<p>Applications A drug used to treat tuberculosis.<br>References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005),<br></p>Formula:C14H8D6N215N2O4Purity:>80%Color and Shape:NeatMolecular weight:310.31(S)-(+)-Ibuprofen
CAS:<p>(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).</p>Formula:C13H18O2Purity:99.51% - 99.86%Color and Shape:Colourless Crystalline SolidMolecular weight:206.28α-Methyl-2-(2-methylpropyl)benzeneacetic Acid
CAS:Controlled Product<p>Applications α-Methyl-2-(2-methylpropyl)benzeneacetic Acid is used in pharmaceutical analysis, and also a constituent of major drug tablets.<br>References Asmus, P.A., et al.: J. Chromatogr., 331, 169 (1985)<br></p>Formula:C13H18O2Color and Shape:NeatMolecular weight:206.281Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers)
CAS:<p>Stability Hygroscopic, Not stable in aqueous solutions.<br>Applications Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers) (cas# 115075-59-7) is a compound useful in organic synthesis.<br></p>Formula:C19H26O8Color and Shape:NeatMolecular weight:382.40α-(4-Isobutylphenyl)ethanol
CAS:<p>Applications The photodegradation product of Ibuprofen (I140000). Shows cytotoxicity activity.<br>References Kobayashi, S., et al.: Biochemistry, 23, 4589 (1984), Karthein, R., et al.: Eur. J. Biochem., 171, 313 (1988), Maranon, M., et al.: Phytochem., 37, 1217 (1994),<br></p>Formula:C12H18OColor and Shape:Colourless LiquidMolecular weight:178.27Furosemide-d5
CAS:Controlled Product<p>Applications Labelled Furosemide (F865000). Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979)<br></p>Formula:C12D5H6ClN2O5SColor and Shape:WhiteMolecular weight:335.774'-Isobutylacetophenone
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Formula:C12H16OColor and Shape:Colourless To Light YellowMolecular weight:176.25Sulfacetamide-d4
CAS:Controlled Product<p>Applications Sulfacetamide-d4 is the isotope labelled analog of Sulfacetamide. Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties<br>References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);<br></p>Formula:C8H6D4N2O3SColor and Shape:NeatMolecular weight:218.274-Amino-6-chloro-1,3-benzenedisulfonamide
CAS:Controlled Product<p>Impurity Hydrochlorothiazide EP Impurity B<br>Applications Diuretic. Hydrochlorothiazide EP Impurity B.<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Joshi, S., et al.: J. Pharm. Biomed. Anal., 52, 362 (2010), Castillo-Garit, J., et al.: Eur. J. Pharm. Sci., 39, 30 (2010),<br></p>Formula:C6H8ClN3O4S2Color and Shape:White To Light BrownMolecular weight:285.734’-Hydroxyacetophenone Oxime
CAS:Controlled Product<p>Impurity Paracetamol EP Impurity G<br>Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Formula:C8H9NO2Color and Shape:NeatMolecular weight:151.16rac cis-3-Hydroxy Glyburide
CAS:Controlled Product<p>Applications rac cis-3-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic (MII-metabolite).<br>References Heptner, W., et al.: Pharmaceut. Res., 5, 215 (1984), Rydberg, T., et al.: Br. J. Clin. Pharm., 43, 373 (1997),<br></p>Formula:C23H28ClN3O6SColor and Shape:NeatMolecular weight:510.004-Deschloro-4-(2-furanylmethyl)amino Furosemide
CAS:<p>Impurity Furosemide EP Impurity D<br>Applications 4-Deschloro-4-(2-furanylmethyl)amino Furosemide (Furosemide EP Impurity D) is a Furosemide (F865000) Impurity.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979)<br></p>Formula:C17H17N3O6SColor and Shape:White To Dark BrownMolecular weight:391.404-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride
CAS:<p>Applications 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.<br>References Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)<br></p>Formula:C14H13ClN2O2·HClColor and Shape:NeatMolecular weight:313.18Hydrochlorothiazide Dimer
CAS:<p>Impurity Hydrochlorothiazide EP Impurity C<br>Applications N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide (Hydrochlorothiazide EP Impurity C) is an impurity in bulk Hydrochlorothiazide. Dimer Impurity C.<br>References Daniels, S.L., et al.: J. Pharm. Sci., 70, 211 (1981), Fang, X., et al.: Pharm. Res., 14, 691 (1997),<br></p>Formula:C15H16Cl2N6O8S4Color and Shape:Off-WhiteMolecular weight:607.49Sulfadimethoxine-d4
CAS:Controlled Product<p>Applications Sulfadimethoxine-d4 is a isotope labeled version of Sulfadimethoxine (S699060), a sulfonamide antibiotic.<br>References Seki, et al.: Arzneim.-Forsch., 15, 1441 (1965), Bohni, et al.: Chemotherapy, 14, 195 (1969),<br></p>Formula:C12H10D4N4O4SColor and Shape:NeatMolecular weight:314.35Ibuprofen Related Compound (2,3-Dihydroxypropyl 2-(4-Isobutylphenyl)Propanoate)
CAS:Controlled Product<p>Applications Ibuprofen Related Compound is used for research purposes on Ibuprofen soft capsules for the investigation of unknown impurities.<br>References Bao, S., et al.: Yaowu Fenxi Zazhi, 35, 97 (2015)<br></p>Formula:C16H24O4Color and Shape:ColourlessMolecular weight:280.36Limaprost-d3 (>90%)
CAS:Controlled Product<p>Applications Labelled Limaprost (L461500). Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Formula:C22H33D3O5Purity:>90%Color and Shape:NeatMolecular weight:383.544-Nitroso Sulfamethoxazole, > 90%
CAS:Controlled Product<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Formula:C10H9N3O4SPurity:>90%Color and Shape:NeatMolecular weight:267.26Sulfachlorpyridazine-d4
CAS:Controlled Product<p>Applications Labelled analogue of Sulfachlorpyridazine, an antibacterial compound.<br>References Wammer, K.: Environ. Toxicol. Chem. 25, 1480 (2006);<br></p>Formula:C10H5D4ClN4O2SColor and Shape:NeatMolecular weight:288.75Mefenamic Acid-d3 (major)
CAS:Controlled ProductFormula:C15H12D3NO2Color and Shape:Light YellowMolecular weight:244.35-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine
CAS:<p>Stability Hygroscopic<br>Applications 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, is a derivative of Trimethoprim (T795615), an antibacterial agent. 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, is a possible potent and selective inhibitor targeting dihydrofolate reductase of C. hominis, used for the treatment of Cryptosporidiosis.<br>References Popov, V. M., et al.: Bioorg. Med. Chem. Lett., 16, 4366 (2006); Brogden, R.N., et al.: Drugs, 23, 405 (1982);<br></p>Formula:C14H16N4O4Color and Shape:Light Yellow To OrangeMolecular weight:304.30Zonisamide N,N-Dimethylformimidamide
CAS:<p>Applications Zonisamide related compound C.<br></p>Formula:C11H13N3O3SColor and Shape:White To Off-WhiteMolecular weight:267.30N-(2,3-Dimethylphenyl) Mefenamic Acid Carboxamide
CAS:Controlled Product<p>Impurity Mefeneic Acid EP Impurity B<br>Applications N-(2,3-Dimethylphenyl) Mefenamic Acid Carboxamide is a derivative of Mefenamic Acid (M205050); an anti-inflammatory agent and analgesic.<br>References Winder, C.V., J. Pharmacol. Exp. Ther., 138, 405 (1962)<br></p>Formula:C23H24N2OColor and Shape:NeatMolecular weight:344.45
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